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Farida Ariani
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Journal : GANEC SWARA

 1 
PROTEIN RAS-LIKE PROTEINS FROM RAT BRAIN SEBAGAI TARGET PENGHAMBATAN PERKEMBANGAN SEL KANKER SUKANTY, NI MADE WIASTY; SAPUTRA, I PUTU BAYU AGUS; ARIANI, FARIDA; YUNITA, LINA; DEWI, NOVIANTI TYSMALA
GANEC SWARA Vol 17, No 4 (2023): Desember 2023
Publisher : Universitas Mahasaraswati K. Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35327/gara.v17i4.661

Abstract

Ras-like proteins from rat brain (Rab) is one of the crucial proteins in the process of intracellular transport. Rab plays a role in delivering vesicles from the donor membrane to the acceptor membrane. Vesicles contain various molecules that are important in cell growth and development. These molecules are generally involved in some signaling pathways. In carrying out its functions, Rab needs to be activated first. The activation process of Rab involves various proteins. Thus, Rab activation and deactivation control are critical to regulating the movement of the transferred molecules. In cancer, there is an uncontrolled activation and deactivation of Rab. Rab's involvement in various signaling pathways by providing molecules needed for growth and development is a basis for increasing the speed of growth and development of cancer cells. Although Rab is not the main factor causing cancer, it can help the development of cancer. So, it can be one of the keys to controlling the transfer of molecules involved in the growth and development of cancer cells. There are several methods related to the activation of Rab for molecular transport. Rab activation inhibition by Rab inhibitors and inhibitors of Rab activating proteins and the use of miRNAs can prevent molecule transport. Thus, control of Rab activation can be an alternative to suppress the growth and development of cancer cells.
Co-Authors , Novi Yanti Abdul Kadir Afnita, Nora Akmil Rahmi Alfian Hamsi Almi Syafroza Amlys, Amlys Syahputra Silalahi Amris, Firda Khairati Andrianto Andrianto Anisah Annanda, Yefri Arief Arafat Hankam Aulia Fitri Aulia Fitri, Aulia Azzahra Vidi Umaira Bayu Bresman P Siboro Bustami Syam Dahlan Tanjung Dardanila, Dardanila Darlan, Lalu Ahmad Dedy Suhendra Desimal, Iwan Dewi, Novianti Tysmala Dewi, Novianty Tysmala Dian M. Nasution Dwi Widayati, Dwi Eddy Sutadji Elisabeth Ginting Erin Ryantin Gunawan Erwin Erwin Eva Sartini Eva Sartini Bayu Eva, Eva Sartini Bayu Fachry Abda El Rahman Fahmi Bakrie Ananda Saragih Farel H. Napitupulu Fidia, Salsabila Nurul Firda Khairati Amris Fitria, Rahmayani Ginting, Elizabeth Habibullah, Makmur Hankam, Arief Arafat harfarici, Rici Gusti Hariadi , Hariadi Susilo Hasdari, Hasdari Helmi Rangkuti Hendrizal Hendrizal Hendrizal Hendrizal I Putu Bayu Agus Saputra Idris, Saufi Zahra Ikhsan Siregar Ikhwansyah Isranuri Indra N. T. Jauhari, M. Thontowi Juanda, Rizky Juanda Khalida Syahputri Laksmi Nur Fajriani Lina Yunita Lina Yunita M Tafsin M. Sabri Ma'ruf, Ma'ruf Tafsin Mahadi Makmur Habibullah Marragi M. Martin Kustati Martin Kustati Muhammad Ramadhan Muhsin, Lalu Busyairi MULYADI Nasution, Indriani Ni Made Wiasty Sukanty Ni Made Wiasty Sukanty Ningsih, Sri Wahyuni Ninsix, Retti Nora Afnita Novia Zuriatun Solehah Nur Cholis Nur’ainun Nurhasnah Nurhasnah Nurva Dillatul Vatin Pakpahan, Dion Peni Patriani Prinata, Fadhil Surya Pulungan, Bgd. Sinomba Pebi Nanda Raden Mohamad Herdian Bhakti Rahmadinur, Wisda Rahmi M Sari Ramadan, Prima Ramadhan, Muhammad Ramadhan Reflianto, Reflianto Retti Ninsix Rezki Amelia Rosliana Lubis Rozitawati, Mona Sabaniah, Nofetriani Saib Suwilo Saputra, Syahnan Sarjana Sembiring, Ferry Septiani, Liza Silalahi, Amlys Syahputra Suari, Muhammad Rayhan Suci N. Sandi Sukanty, Ni Made Wiasty Suprianto Suprianto Susanti, Baiq Indah Susilo, Hariadi Syahrul Abda Syamsuar Syamsuar, Syamsuar Syamsurizal - - Syarif, Abdul Azis Tafsih, Ma'Ruf Tafsin, Ma’ruf Terang UHS Ginting Tri Septian M. Tugiman Tugiman Tugiman Tulus Tulus B Sitorus Tulus Burhanuddin Sitorus Tulus Tulus Umaira, Azzahra Vidi Vatin, Nurva Dillatul Wahyuni, Dian Eka Mayasari Sri Wandi, Joni Indra Widani Darma Isasih Yunita, Lina Yunus Nasution, Ahmad Zein, Muhammad Zen, Zelhendri Zulhendri Zen Zulkifli Lubis