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All Journal International Journal of Public Health Science (IJPHS) HAYATI Journal of Biosciences Bioscience Jurnal Teknologi Pangan dan Gizi Pharmaciana: Jurnal Kefarmasian Media Farmasi : Jurnal Ilmu Farmasi (Journal Of Pharmaceutical Science) Indonesian Journal of Biotechnology Journal of Agromedicine and Medical Sciences Biota Bioeksperimen: Jurnal Penelitian Biologi JURNAL PENGABDIAN KEPADA MASYARAKAT Journal of Tropical Biodiversity and Biotechnology Medical Laboratory Technology Journal Jurnal Biodjati THE JOURNAL OF MUHAMMADIYAH MEDICAL LABORATORY TECHNOLOGIST JURNAL GALUNG TROPIKA Jurnal Biologi Tropis BIOEDUSAINS: Jurnal Pendidikan Biologi dan Sains Jurnal Ilmu Kefarmasian Indonesia Jurnal Pengabdian kepada Masyarakat Nusantara Nusantara Science and Technology Proceedings Jurnal Insan Farmasi Indonesia Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Livestock and Animal Research Journal of Biotechnology and Natural Science Jurnal Katalisator Medical Sains : Jurnal Ilmiah Kefarmasian
Maliza, Rita
Faculty Of Science And Applied Technology, Ahmad Dahlan University
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health Social Sciences Veterinary Other

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The Relationship between Sea Surface Temperature and Chlorophyll-a Concentration on Mackerel Fish (Rastrelliger kanagurta, Cuvier 1816) Catch Results on Sea Waters of Bengkulu City Ramadanti, Dhea; Nurdin, Jabang; Maliza, Rita
Jurnal Biologi Tropis Vol. 25 No. 4 (2025): Oktober-Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v25i4.9930

Abstract

This study investigates the relationship between sea surface temperature (SST) and chlorophyll-a concentration in relation to the catch results of mackerel fish (Rastrelliger kanagurta) in Pulau Tikus Beach, Bengkulu City. Remote sensing data from the Aqua MODIS satellite sensor were analyzed over a 12-month period (May-April 2025) to assess monthly fluctuations in SST and chlorophyll-a as indicators of marine productivity. SST values ranged from 28.9°C to 31.2°C, matching the optimal thermal range for mackerel spawning. Chlorophyll-a concentrations ranged from 0.5 to 3.4 mg/m³, indicating a high abundance of phytoplankton and biologically fertile waters. Fishing coordinate data showed that the highest mackerel catches occurred around Pulau Tikus, with Robin-type boats operating approximately 7-8 nautical miles offshore. The relationship between SST and chlorophyll-a revealed that increasing SST was associated with elevated chlorophyll-a levels at depths of 8-15 meters, thereby increasing the probability of mackerel presence.
Integration of genomic databases and bioinformatic approach to identify genomic variants for sjogren’s syndrome on multiple continents Puspitaningrum, Anisa Nova; Perwitasari, Dyah Aryani; Adikusuma, Wirawan; Djalilah, Gina Noor; Dania, Haafizah; Maliza, Rita; Faridah, Imaniar Noor; Sarasmita, Made Ary; Rezadhini, Melodia; Cheung, Rocky; Irham, Lalu Muhammad
Media Farmasi: Jurnal Ilmu Farmasi Vol. 19 No. 2: September 2022
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/mf.v19i2.23706

Abstract

An autoimmune disorder is an abnormality that causes a disease. It is caused by a weakened immune system. One of the autoimmune diseases is Sjogren’s syndrome, which affects the salivary and lacrimal glands and causes dry mouth, dry eyes, and dry skin. Sjogren’s syndrome influences humans of every age, with the symptoms occurring at the age of 45–55 years and rarely in children. One of the factors causing Sjogren’s syndrome is genetic disorders. To identify genes that can influence Sjogren’s syndrome in this study, we used several databases, including GWAS Catalog, HaploReg Version 4.1, GTEX portal, and Ensembl, particularly to identify the gene expression profiles of TNIP1, TNFAIP3, and IRF5 and the quantitative properties of locus’ expression. This research showed that the missense variants and splice donor rs2233290, rs2230926, and rs2004640 influenced the susceptibility of autoimmune diseases, especially Sjogren’s syndrome, in the fibroblast tissue, sigmoid tissue, sigmoid colon, skin, esophagus, and adrenal glands. The allele frequency of each variant was then assessed in African, American, European, and Asian populations. Our data showed that TNIP1, TNFAIP3, and IRF5 genes in African and American populations had higher frequencies than in the Asian population. This implies that the last of the aforementioned populations might be relatively susceptible to the autoimmune disease Sjogren’s syndrome.
PELATIHAN KAIN ECOPRINT MENGGUNAKAN ZAT PEWARNA ALAMI TANIN DAUN MANGGA DAN KETAPANG BAGI KELOMPOK PKK KELURAHAN KAMPUNG JUA, PADANG, SUMATRA BARAT maliza, Rita
JURNAL PENGABDIAN KEPADA MASYARAKAT Vol. 29 No. 4 (2023): OKTOBER-DESEMBER
Publisher : Universitas Negeri Medan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24114/jpkm.v29i4.50848

Abstract

Kegiatan pelatihan ecoprint yang diadakan untuk Ibu-Ibu PKK di Kelurahan Kampung Jua, Padang sebagai bagian dari upaya untuk mempromosikan seni ecoprint yang ramah lingkungan dengan menggunakan zat warna alami yang ada dilingkungan sekitar. Tahapan kegiatan pengabdian pada masyarakat ini yaitu sosialisasi, demonstrasi, dan praktek langsung. Ibu-Ibu PKK diikut sertakan dalam pembuatan kain ecoprint dengan menggunakan larutan tanin daun mangga dan daun ketapang, dan juga memanfaatkan bunga serta daun-daun yang dicetak dikain nantinya. Pada kegiatan ini, Ibu-Ibu PKK menghasilkan kain ecoprint yang berbeda-beda warna dengan menggunakan zat warna alami tanin yang berbeda dan juga Ibu-Ibu PKK dilibatkan dalam diskusi tentang pentingnya pelestarian alam, pemanfaatan bahan-bahan alami, dan dampak positif dari eco-printing terhadap lingkungan. Evaluasi program dilakukan melalui kuesioner, dari data kuisioner menunjukkan peningkatan signifikan dalam pemahaman peserta tentang teknik ecoprint menggunakn zat pewarna alami, serta dampak positif pada pemberdayaan ekonomi dan lingkungan lokal. Pelatihan ecoprint dapat menjadi suatu strategi yang efektif dalam mencapai tujuan pemberdayaan masyarakat lokal dan dapat membawa manfaat positif dalam aspek seni, ekonomi, dan lingkungan.
Effects of Glyphosate on Cognitive Development, Sensory Sensitivity and Locomotor Balance in Male Rats Fadillah, Fadillah; Irwan , Reziq Marchellino; Afif , Muhamad; Tofrizal , Allimuddin; Zuhir, Elvina; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.6978

Abstract

Glycophate is the active ingredient in RoundupⓇ hebicide, which is commonly used in agriculture. Exposure to the herbicide glyphosate may affect the development of Parkinson Disease in humans. pre-natal and post-natal exposure to glyphosate exerts neurological effects and neuropsychiatric effects, even at low concentrations. This study aimed to examine the effects on cognitive, sensory and motor development in male rats exposed to the active ingredient glycophate in RoundupⓇ at various concentrations. In this study using test animals in the form of male rats with an age of 10 weeks, then the rats were divided into 4 treatment groups, namely the normal group, 100 µL, 50 µL, and 25 µL RoundupⓇ, induction was given orally every day for 4 weeks. Then at the last week, the body weight of the rats was measured and several tests were conducted to see the effect of glycophate induction on rat cognition through the morris water maze and y maze tests, sensory development through the hot plate test, and rat motor development through the hanging wire test. The results showed that glyphosphate administration affected the body weight of the rats, and affected the cognitive development of the rats. The 50 µL dose treatment group showed the most visible effect of glycophosphate exposure on cognitive tests compared to other groups. In the sensory test, the 50 µL ml dose treatment group also had low sensitivity compared to other groups, and low motor ability compared to other groups. Glycophate was seen to affect the cognitive, sensory and motor development of the rats.
Potential of Mesenchymal Stem Cells (MSCs) for Various Disease Therapy: Systematic Review Aulia, Annisa; Rismayani, Dessy; Nopiyanti, Tita; Noli, Zozy Aneloi; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7006

Abstract

Mesenchymal stem cells (MSCs) are a type of multipotent stem cells that can be found in various tissues of the body, possessing good regenerative qualities and promising immunomodulatory abilities for therapy in various medical conditions. MSCs can be obtained from bone marrow, umbilical cord, adipose tissue, and Warthon's jelly. This study aims to present a systematic review of the use of mesenchymal stem cells in disease therapy, by evaluating the latest evidence regarding their efficacy and safety in various therapies. This review uses literature review methods from international data bases such as PubMed and Google Scholar. The total number of articles obtained from the database was 49 articles. These articles were then filtered using inclusion and exclusion criteria, resulting in 22 articles for this systematic review. The research findings indicate that MSCs therapy has been used for the treatment of liver fibrosis, diabetes mellitus, spinal cord injury, and COVID-19. In MSCs therapy, mechanisms involved paracrine effects (MSCs produce cytokines, growth factors, and other proteins); immunomodulation (MSCs can suppress immune cell activation, inhibit lymphocyte proliferation, modulate natural killer T cell activation, and produce anti-inflammatory factors); angiogenesis (MSCs are capable of stimulating the growth of new blood vessels through secretion of VEGF and FGF); cellular differentiation; and anti-fibrotic effects. This is what makes MSCs potentially promising as an evolving alternative treatment.
Systematic Review: Cytotoxicity Test of Bioactive Compounds of Asteraceae Family Plant Extracts on HeLa Cell Line Yanti, Windi Nofri; Hulrahma, Mifta; Aprilia, Kharisma Annisa; Roza, Amelia; Ilham, Kurniadi; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7007

Abstract

HeLa cancer cells are cervical cancer cells due to Human Papillomavirus (HPV 18) infection and thus have different properties from normal cervical cells. In recent decades, the number of plant species used in alternative medicine for cervical cancer-related purposes has increased. This systematic review aims to facilitate the review of the potential bioactive compounds of plant medicines and analyze how medicinal plants affect cancer cells. Scientific related questions, databases to be used, selection of keywords, inclusion and exclusion criteria, definition of results and conclusions of selected articles are all elements included in this research search strategy. Eight articles met the inclusion criteria and examined plant-derived compounds for their toxicity to HeLa cell lines. The bioactive compounds of this plant inhibit the growth of cancer cells.
Potential Bioactive Compounds of Plant as Anticancers in Lung Cancer A549 Cell Line: A Systematic Review Zulfikri, Elzam Naufal; Ibrahim, Muhammad Hamdi; Elisa, Tasya Putri Pratama; Nelvi, Dennisa Arra; Ilham, Kurniadi; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7008

Abstract

Cancer is one of the non-communicable diseases of global concern the world. Lung cancer is the leading cause of cancer death worldwide, and is the highest cause of death in both men and women at 18% of the world's 9.9 million cancer deaths. Efforts to prevent and cure cancer include using chemotherapy and anti-cancer drugs. Plants are rich in secondary metabolites which are byproducts of plant metabolism that have proven to be useful for the discovery and development of many medicines’ discovery and development of medicines. This article aims to review the potential of plant bioactive compounds that play a role in anticancer activity in lung cancer A549 cell line. In this journal review we used PubMed Centre database to identify articles published between 2014 and 2024. 10 studies were obtained from keywords concerning extracts bioactive compounds of plants used as lung anticancer against A549 cell line. From the results obtained, it was reported that plants containing active compounds such as polyphenols, terpenoids (oleanolic acid, ursolic acid, betulinate, ferruginol), flavonoids (tiliroside), and alkaloids can act as anticancer agents and are proven to inhibit the growth of lung cancer A549 cell line.
Effects of Low Protein Diet on Body Weight and Hematological Parameters in Rats Zikrah, Azizah Amatu; Santoso, Putra; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 3 (2024): July - September
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i3.7066

Abstract

Malnutrition is a condition in which the body is deficient or excessive in macronutrients and micronutrients such as carbohydrates, fats, proteins and vitamins. Malnutrition causes changes in body weight and blood tissue that inhibit the development of hematopoietic cells, resulting in anemia, leukopenia and bone marrow hypoplasia. This study aimed to examine the effect of feeding a diet with a protein level of 12% and 20 % for 6-week to Wistar rats. The parameters seen are the impact on body weight and selected hematological parameters included white blood cell, monocyte, lymphocyte, granulocyte, hemoglobin and mean corpuscular volume. This study found that rats fed with 12% protein showed significant differences in body weight and several hematological parameters such as monocytes, lymphocytes, hemoglobin and mean corpuscular volume compared to normal.
Effectiveness of Bioactive Compounds Against T47D Breast Ductal Carcinoma Cell Line: A Systematic Review Mahardika, Riris Srikandi; Putri, Fadilatul Rahmi; Azzahra, Layla; Maliza, Rita; Ilham, Kurniadi; Hamdani, Afif
Jurnal Biologi Tropis Vol. 24 No. 4 (2024): Oktober - Desember
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i4.7067

Abstract

Breast cancer is one of the highest causes of death from non-communicable diseases and is the second leading cause of death in the world after lung cancer. Cancer treatment causes bad side effects for the body, so researchers are currently looking for compounds with anticancer properties that come from plants. Plants contain secondary metabolites that act as antioxidants and anticancer, making them a potential source of cancer drugs. This article was written to determine the potential and content of various herbal plants as cell proliferation agents against breast cancer T474 cells. We collected articles from previous studies that had been conducted on this topic using the PubMed database in our review and selected twelve articles published in the last ten years with a period of 2014-2024. From the results obtained, it can be concluded that plants contain antioxidant compounds such as alkaloids and flavonoids which can act as anticancer agents and inhibit the growth of breast cancer.
Physical Quality and Organoleptic Testing of Golden Apple Snail Pomacea canaliculata) Mucus Gel as a Burn Treatment Fadhilah, Diana; Nadjmir, Mikail; Adilla, Ardis Trianita; Santoso, Putra; Maliza, Rita
Jurnal Biologi Tropis Vol. 24 No. 1b (2024): Special Issue
Publisher : Biology Education Study Program, Faculty of Teacher Training and Education, University of Mataram, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jbt.v24i1b.8023

Abstract

Golden Apple Snail (Pomacea canaliculata) secretion has traditionally been used for wound healing due to its high protein content, which promotes cell regeneration and inhibits inflammation. This study aims to utilize this secretion to formulate a topical gel for burn treatment, providing a controlled use for the abundant, invasive species in agricultural areas. Gel formulations with varying secretion concentrations (10%, 15%, and 20%) were evaluated for organoleptic properties, homogeneity, pH, adhesion, spreadability, and viscosity. Results indicated that all formulations were homogeneous and had pH values within the acceptable range (4.5-6.5). The 15% secretion gel showed the highest user acceptance and optimal balance between spreadability and adhesion, but all formulations had higher than standard viscosity and lower spreadability. Adjusting carbopol concentration is recommended to improve the gel's physical properties. The 15% formulation is the most promising for effective topical application.
Co-Authors . Mansyurdin Adam Raihan Priambada Adi Wira Septama Adilla, Ardis Trianita Adnan, Adnan Afdhal Raihan Afdhal Raihan Afif , Muhamad Aldi Tamara Rahman Alfiatul Laila Alimuddin Tofrizal Allimuddin Tofrizal Amelia Roza, Amelia Angga Illahi Kurnia Illahi Angga Kurnia Illahi Anisa Nova Puspitaningrum Aprilia Cassa Nova Aprilia, Kharisma Annisa Asful, Ferdhinal Ashrifurrahman, Ashrifurrahman Aszareta, Muhammad Andoni Athika Darumas Putri Aulia Rahmi Aulia, Annisa Ayu Rosemeilia Dewi Aziz, M. Abdul Azizah Amatu Zikrah Azizah Amatu zikrah Azzahra, Layla Bayu Tri Murti Bramadi Arya Cahyani, Dini Chairunnisa Azzahra Azzahra H Cheung, Rocky Dahelmi Dahelmi Diana Fadhilah Diani Fatmawati Dyah Aryani Perwitasari Efa Refiani Efrizal Efrizal Eli Ratni Elisa, Tasya Putri Pratama Elni Fatimah Era Refiani Esa Savitri Eti Yerizel Fadhilah, Diana Fadillah Fadillah Fadillah Fajri Hidayat Febriofca Galih Yatalaththov Firmansyah, Tio Gina Noor Djalilah Haafizah Dania Haafizah Dania Haafizah Dania Hamdani, Afif Haris Setiawan Harry Nugroho Eko Surniyantoro Henny Herwina Hevi Horiza Hulrahma, Mifta Husna Fitri Husna Fitri Husna Fitri Husna Fitri Hylda Ibrahim, Muhammad Hamdi Ika Wahyuni Ikrimah Nisa Utami Ilham, Kurniadi Illahi, Angga Illahi Kurnia Imaniar Noor Faridah Imaniar Noor Faridah Imaniar Noor Faridah Inggita Utami Irwan , Reziq Marchellino Ivan Petrovsky Jabang Nurdin Jannati Aulah Janra, Muhammad Nazri Jasmi Jefrial Santoso Kania Agustina Kiky Martha Ariesaka Kurniadi Ilham Lalu Muhammad Irham Lestari, Mardiana Puji Liana Fairuzannah Mahdiana Listiatie Budi Utami Lutfi Sukma Pratiwi Made Ary Sarasmita Mahardika, Riris Srikandi Melinda Widianingrum Melinda Widianingrum Melinda Widyaningrum Melodia Rezadhini Miftahul Ilmi Moh. Mirza Nuryady Muhammad Hamdi Ibrahim Muhammad Idris Muhammad Idris Muhammad Idris Muhammad Ilham Hisbullah Muhammad Nazri Janra Nabilah Adzra Fahlevi Nabilah Rahmachila Azura Nadjmir, Mikail Nanik Sulistyani Nastiti Rahajeng Nelvi, Dennisa Arra Ni Made Ary Sarasmita Nofrita Nofrita Nofrita Nofrita Nopiyanti, Tita Nur Aida Nur Rahmah Hidayati Nurul Annisa Nurwijayanti Oktira Roka Aji Petrovsky, Ivan Pradika, Jaka Pratama Elisa, Tasya Putri Pratama, Kharisma Pratama, Raihan Anugrah Puspitaningrum, Anisa Nova Puti Khairunnajwa Amar Putra Santoso Putri Lestari Putri, Fadilatul Rahmi Putri, Syntia Mai Raihan, Afdhal Ramadanti, Dhea Rarastoeti Pratiwi Resti Rahayu Rezadhini, Melodia Reziq Marchellino Irwan Ridho, Muhammad Syifa'ur Rifai, Fauziah Novita Putri Rihadatul Aisyah Rilwan Efendi Rismayani, Dessy Rizma Nurul Akhlas Robby Jannatan Rocky Cheung Rocky Cheung Saraswati, Utami Sinurat, Arthauly Yopita Siti Rokhimah Sumaryati Syukur Sutri Wulansari Safril Syaiful Adam Maulana Syaifullah Syaifullah Syakira Tiara Rezvi Syamsuardi Syamsuardi Tasya Putri Pratama Elisa Tio Firmansyah Tofrizal Tofrizal , Allimuddin Tofrizal, Alimuddin Tur Rahardjo Utami Saraswati Wardatul Aini Wilson Novarino Wirawan Adikusuma Yanti Lusiyanti Yanti, Windi Nofri Yeni Alfiana Ratnasari Yudha Rizky Nuari Yustia Tuti Zaini Zaini Zikrah, Azizah Amatu Zozy Aneloi Noli Zozy Aneloi Noni Zuhir, Elvina Zulfikri, Elzam Naufal