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All Journal Jurnal Ilmu Pertanian Jurnal Pendidikan Matematika dan IPA bionature AL KAUNIYAH Biogenesis: Jurnal Ilmiah Biologi Teknosains: Media Informasi Sains dan Teknologi Prosiding Seminar Biologi Elkawnie Jurnal Ilmiah Ekonomi Islam BIOTROPIC The Journal of Tropical Biology Indonesia Journal of Halal AkMen JURNAL ILMIAH AL-HAYAT: Journal of Biology and Applied Biology Biota jurnal Ilmu Pertanian (Agricultural Science) Scripta Biologica Jurnal Biotek Journal of Islam and Science Muttaqien; Indonesian Journal of Multidiciplinary Islamic Studies El-Iqtishady Iqtishaduna : Jurnal Ilmiah Mahasiswa Hukum Ekonomi Syariah Jurnal Studi Ekonomi dan Bisnis Islam (SEBI) International Journal Mathla'ul Anwar of Halal Issues Formosa Journal of Multidisciplinary Research (FJMR) Tadayun: Jurnal Hukum Ekonomi Syariah Robust: Research of Business and Economics Studies Al Jahiz: Journal of Biology Education Research Filogeni: Jurnal Mahasiswa Biologi SAUJANA : Jurnal Perbankan Syariah dan Ekonomi Syariah Southeast Asia Journal of Graduate of Islamic Business and Economics Belalek Jurnal Bisnis dan Kewirausahaan Tropical Genetics Journal of Innovative and Creativity SEGARA : Jurnal Pengabdian Kepada Masyarakat Jurnal Ilmiah Ekonomi, Akuntansi dan Pajak Kalam Al Gazali: Education and Islamic Studies Journal PESHUM Berita Biologi
Cut Muthiadin
Universitas Islam Negeri Alauddin Makassar
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Journal : Tropical Genetics

 1 
Premarital screening and probabilities of genetic disease in premarital screening and probability of genetic diseases in couples preparing for marriage Muthiadin, Cut
Tropical Genetics Vol. 3 No. 1 (2023):
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v3i1.33

Abstract

Genetic diseases are known to be difficult and could not be avoided. The disease is obtained from mutations and changes in genetic traits that are passed on from one or both genes from parent to child. Genes carrying traits or diseases can be dominant and recessive, their location can be on the autosomal chromosome or sex chromosome X or Y. This study was conducted on premarital female respondents with defined inclusion criteria. Data were collected through a google form questionnaire. A total of 110 respondents with several parameters of genetic counseling. The result was obtained that all respondents have known that certain diseases can be inherited. However, from all respondents, it was found that they had low knowledge of genetic counseling and premarital screening. From the respondent's data, it was also found that only 17% of respondents knew the history of the disease of the prospective partner and their family. In this case, it can be said that respondents might be carry the sick gene which means the probability that their child will carry the same gene is 50% normal: 50% sick. By screening, it might be predicted that the couple will be able to find out the potential diseases that will be passed on to their offspring later. Latest 48% decided to cancel and 26% said they did not agree and stated to continue the plan of marriage. Lack of knowledge about risk of genetic disorders need education about premarital screening to increase this information and premarital screening to the public.
The potential of microsatellite markers on the identification of various ethnic alleles in Indonesia Harja, Husnul Sri Mulyani; Muthiadin, Cut
Tropical Genetics Vol. 3 No. 1 (2023):
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v3i1.37

Abstract

Indonesia is an archipelagic country with a high level of population diversity such as religion, ethnicity, culture and also genetic diversity. Environmental factors also have an impact on the genetic variation and diversity of the population, including high mobility and migration triggering the tendency for inter-ethnic marriages to occur. This environmental factor is one of the reasons for research based on DNA analysis on ethnicity in Indonesia for the purpose of forensic identification. One of the DNA analyzes for forensic identification is the microsatellite DNA analysis method with a high sensitivity level.
First record of characterization C-KIT mutation in buccal swab DNA of piebaldism suspect balo from balo community, Pujananting South Sulawesi Muthiadin, Cut; Arisuryanti, Tuty; Aziz, Isna Rasdianah; Hajrah, Hajrah; Khatimah, Khusnul; Hidayat, Muhammad Tasri
Tropical Genetics Vol. 4 No. 1 (2024): Genetics
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v4i1.67

Abstract

ABSTRACT Piebaldism is a disorder in the area of ​​the body caused by an autosomal genetic predominance of the development of melanocytes.The method used in this study is a qualitative method which aims to determine the variation of the KIT-c gene present in the To Balo mucosa samples.The results of this study indicate thatThe change is caused by a point mutation process where in patients with piabeldism the nucleotide bases of sequence 1391 and 1392 undergo changes, where the normal nucleotide base adenine (A) changes to cytosine (C) and cytosine (C) changes to adenine (A). So it can be concluded that the To Balo community in Bulo-Bulo village, Pujananting District, Barru Regency, South Sulawesi suffers from an autosomal dominant hereditary disease or piebaldism.
Literature review on the genetic variability of Escherichia coli in clinical isolates: relationship with antibiotic resistance and virulence factors Rum, Magfirah Rahimah; Muthiadin, Cut
Tropical Genetics Vol. 5 No. 1 (2025): Genetics
Publisher : Genetikawan Muda Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24036/tg.v5i1.82

Abstract

Escherichia coli is a natural flora found in the intestine, but Escherichia coli is also a major repository of resistance genes that may be responsible for treatment failure in humans and animals. This study aims to understand and evaluate the genetic variability of Escherichia coli in clinical isolates and to determine the correlation between genetic variability and antibiotic resistance. This study uses a literature review method. This study presents the results of a search for studies related to the topic, namely the genetic variability of Escherichia coli in clinical isolates and the relationship with antibiotic resistance and virulence factors. The criteria for articles used as data are articles published in the last 10 years, namely from 2015 to 2025. Based on the research that has been done, it can be concluded that genetic variability in Escherichia coli in clinical isolates plays an important role in adaptation, pathogenicity, and antibiotic resistance. Mechanisms such as horizontal gene transfer (HGT), mutations, and genome rearrangements allow E. coli to acquire virulence genes and antibiotic resistance genes, such as genes encoding extended-spectrum β-lactamases (ESBLs) including TEM, SHV, and CTX-M. These genes are often located on mobile plasmids, which support the spread of resistance between bacterial strains and species, complicating infection control and clinical treatment.
Co-Authors Abdul Rauf Muhammad Amin, Abdul Rauf Muhammad Adin Ayu Andriyani AGUS AGUS Ahyar Ahmad Alir, Rahmat Fajrin Amnah, Alifah Zul Amril Andi Nabila Nurfitrah Annisa Zakiyah Darojat Ar. Syarif Hidayat Asbar Hamzah Asmuddin Nasir Asmuddin Natsir Auriga, Fitriani Ayu Andi Indra, Ayu Baiq Farhatul Wahidah Bakri Zakia, Bakri Bin Sapa, Nasrullah Burhan, Eliazar Dedi Mardianto Dedi Susanto Fachrurrazy, Muhammad Fatmawati Nur Febriani, Ayu Ferial, Ferial Firdayana Firdayana Firmansyah, Yuman Fuadi, Ni'ma Ainul Gafur, Muslimah Fitrah Abd Gazali, Megawati Hadidarma, Nasyrah Hafsan, Hafsan Hajrah Hajrah Hajrah Hajrah Hajrah Hajrah Hajrah, Hajrah Halik, Abdul Chadjib Harja, Husnul Sri Mulyani Hartono Helmy Syamsuri, Helmy Hermawan, Isna Ainun Hidayat, Kusnadi S Hidayat, Muhammad Tasri Hidayati, Ulfa Idris Parakkasi Indradewa, Rhian Isna Rasdianah Aziz Isna Rasdianah Aziz Isna Rasdianah Aziz Isna Rasdianah Aziz Isna Rasdianah Aziz Isna Rasdianah Aziz Isna Rasdianah Aziz Isna Rasdianah Aziz Isna Rasdianah Aziz Japar, Rahayu K., M. Yusuf Karmila, Yusri Kartika Khatimah, Khusnul Kholid Albar Khudaer , Faten Khudaer, Faten Kumala, Nur Hakiki Dewi Laily Agustina Lasinrang Aditia Lianah Lianah, Lianah Mahfut Marcia Bunga Pabendon Mashuri Masri Mashuri Masri Mashuri Masri Masita Masita Masriany, Masriany Maulana Maulana Maulana Maulana, Maulana Muh. Khalifah Mustami Muhammad Amin, Abd Rauf Muhammad Amin, Abdul Rauf Muhammad Khalifah Mustami Mukhtar Galib Nasrullah Bin Sapa Nur Alfi Hidayati Nurhaedah ., Nurhaedah Nurhikmah Nurhikmah Nurjannah Nurjannah Nurmayanti, Nurmayanti Nurul Muhlisyah Nurul Muhlisyah Paraikkasi, Idris Parakkasi, Idris Pujarena Putri Idris Rahmat Fajrin Alir Ramlah Ramlah Ramlah Rasnawati Risdayanti Adi Purba Rukmana, Rusmadi Rum, Magfirah Rahimah Rusny Rusny Sapa, Nasrullah Bin Sapinah Sapsuha, Mubasysyyratul Ummah Sijid, St Aisyah Sitti Saenab, Sitti Sri Wahyuni St. Aisyah Sijid St. Aisyah Sijid Sudarmi Sudarmi Sukmawaty, Eka Sumarlin, Abdul Suryafly, Fanny Dhea Syam, Agus Syaripuddin Syaripuddin Tri Cahyanto Tridesianti, Siska Tuti Supatminingsih Tuty Arisuryanti, Tuty Umar, Rahmawati Upreti, Brij Mohan Wahab, Andi Rizki Berliana Zahra Wamaulana, Farlinda Yuniar Harviyanti Zahra, Najmatul Zulkarnain Zulkarnain Zulkarnain Zulkarnain Zulkarnain Zulkarnain