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Hubungan Protein Urin dengan Berat Jenis Urin pada Pasien Nefropati Diabetik Putri, Najwa Naraniya; Kurniati, Intanri; Yuningrum, Hesti; Susianti
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1273

Abstract

Diabetic nephropathy is one of the main causes of end-stage renal failure or End Stage Renal Disease (ESRD) in patients with type 2 diabetes. Diabetic nephropathy is defined as the presence of albumin or protein of more than 30 mg/day in urine on two examinations within a period of 3-6 months, as well as a decrease in the glomerular filtration rate. Urinalysis examination using the dipstick method is carried out for certain indications or suspicions of complications of diabetes mellitus, one of which is diabetic nephropathy. Dipstick examination can detect protein, pH, glucose, specific gravity, ketones, urobilinogen, nitrite, blood, bilirubin, and leukocyte esterase. The specific gravity of urine depends on the concentration of glucose, urea, and protein particles in the solution. Therefore, the purpose of this study was to determine the relationship between protein in urine and specific gravity in patients with diabetic nephropathy. Observational analytical research was conducted with a cross-sectional approach. This study was conducted at the Medical Records Installation of Dr. H. Abdul Moeloek Hospital. The population of this study was diabetic nephropathy patients treated at Dr. H. Abdul Moeloek Hospital in January-December 2023. The sampling technique used the total sampling technique so that 49 samples were obtained that met the inclusion and exclusion criteria. The data obtained were analyzed using the Spearman correlation test. The results showed a correlation coefficient (r) of 0.589 and a significance p-value = 0.000. There is a relationship between urine protein and urine specific gravity in diabetic nephropathy patients.
Peran Anemia Sebagai Faktor Risiko Hipertensi Resisten pada Penyakit Ginjal Kronik Nasution, Salwa Salsabila; Kurniati, Intanri; Ratna, Maya Ganda; Ramadhian, M. Ricky
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1354

Abstract

Anemia is one of the most common complications in chronic kidney disease (CKD) that significantly affects quality of life and prognosis. Anemia is a condition where there is a decrease in iron-rich hemoglobin levels, which functions to circulate oxygen throughout the body. Chronic kidney disease is a kidney condition characterized by abnormalities in kidney structure or function. Men have a 2 times higher risk of developing CKD than women due to their generally poorer lifestyle habits. The condition of insufficient oxygen perfusion to tissues leads to activation of the renin-angiotensin-aldosterone system (RAAS). The RAAS system ultimately produces aldosterone and antidiuretic hormones that cause sodium retention in the body and lead to increased blood pressure. Additionally, anemia can cause changes in blood vessels, where there is an increase in vascular resistance, especially in CKD patients. Studies have also shown that erythropoietin therapy can increase the prevalence of hypertension. Resistant hypertension is a condition where someone suffering from hypertension fails to achieve target blood pressure of <140/80 mmHg in normal individuals and <130/80 mmHg in CKD patients despite adhering to a combination dose of three types of antihypertensive medications. Someone suffering from resistant hypertension must comply with the drug dosage prescribed by the doctor and also improve their lifestyle. This article aims to understand how anemia serves as a risk factor for resistant hypertension in CKD patients. Furthermore, the diagnosis and treatment of resistant hypertension are also discussed in this article.
Peran Shunt Ventrikuloperitoneal dalam Strategi Pengobatan Hidrosefalus Pada Anak : Literature Review Sari, Indah Purnama; Roro Rukmi Windi Perdani; Diana Mayasari; Intanri Kurniati; Fidha Ramayani; Rizki Hanriko; Dewi Nur Fiana
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1357

Abstract

Hydrocephalus is a condition characterized by the accumulation of cerebrospinal fluid (CSF) within the brain's ventricles, presents a significant challenge in pediatric care. The increased intracranial pressure resulting from this CSF buildup can lead to severe neurological damage if left untreated. Ventricular peritoneal shunt (VP shunt) surgery remains a primary surgical intervention aimed at diverting excess CSF, thereby reducing intracranial pressure and mitigating the risk of irreversible neurological damage. This literature review provides a comprehensive review of the role of VP shunts in the management of pediatric hydrocephalus, encompassing a detailed examination of indications and contraindications for shunt placement, various surgical techniques employed, and the effective management of common post-operative complications such as infection, shunt malfunction (obstruction or overdrainage), and hemorrhage. We meticulously analyze current literature data to assess the effectiveness of VP shunts in improving neurological outcomes, fostering cognitive development, and enhancing the overall quality of life for children affected by hydrocephalus. The analysis will incorporate a review of long-term followup studies to evaluate the durability and efficacy of different shunt types and materials. Case studies and clinical experiences are integrated to provide a nuanced understanding of current clinical practices and to highlight the complexities often encountered in managing this condition. Furthermore, this literature review delves into recent advancements in shunt technology, including the development of programmable valves and less invasive surgical approaches. It also addresses the persistent challenges in optimizing hydrocephalus care, emphasizing the crucial need for a multidisciplinary approach involving neurosurgeons, pediatric neurologists, developmental pediatricians, and other healthcare professionals to ensure holistic and individualized patient care. The ultimate goal is to provide practical, evidence-based guidance for healthcare professionals in the effective and safe management of pediatric hydrocephalus using VP shunts, ultimately improving patient outcomes and quality of life.
Tekanan Darah Pada Atlet Al Ghifari, Ghaza Ahmad; Berawi, Khairun Nisa; Graharti, Risti; Kurniati, Intanri
Medula Vol 14 No 10 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i10.1398

Abstract

Blood pressure in athletes is an important topic in exercise physiology studies, given its influence on performance and long-term health. In general, athletes exhibit lower blood pressure at rest compared to sedentary individuals, as a result of the body's adaptation to regular physical exercise. The purpose of this method is to analyze and collate knowledge relevant to the research topic. In this study, 12 articles from national and international journals published between 2015 and 2023 were used. The articles were obtained from databases such as PubMed and Google Scholar. The collected sources were then analyzed using the systematic literature review method. The result of this study is that blood pressure in athletes can be different compared to individuals who are not involved in intense physical activity, due to the body's adaptation to regular exercise. Blood pressure in athletes is influenced by a variety of factors, including sport type, training pattern, age, gender, as well as genetic and environmental factors. Understanding these blood pressure patterns is important for optimizing performance and maintaining cardiovascular health in athletes.
Faktor Gangguan Ginjal dan Diabetes Melitus yang Mempengaruhi Mortalitas Penderita Sindrom Koroner Akut di RSUD Dr. H. Abdul Moeloek Tahun 2020–2021 Fadhlurrahman, Fadhlurrahman; Yonata, Ade; Karima, Nisa; Kurniati, Intanri
Medula Vol 15 No 3 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i3.1676

Abstract

Acute Coronary Syndrome (ACS) is one of the leading causes of cardiovascular mortality worldwide and in Indonesia. Various risk factors have been investigated, yet two important comorbidities that frequently worsen the prognosis are diabetes mellitus and kidney disorders. Diabetes mellitus accelerates atherosclerosis and promotes plaque instability, whereas kidney disorders exacerbate cardiovascular metabolism and restrict therapeutic options due to impaired drug elimination. This study aimed to analyze the influence of diabetes mellitus and kidney disorders on the mortality of ACS patients at Dr. H. Abdul Moeloek General Hospital. An analytic observational study with a cross-sectional design was conducted involving 71 patients diagnosed with ACS during the 2020–2021 period. The main independent variables were diabetes mellitus and kidney disorders, while mortality served as the dependent variable. Data were analyzed using the Chi-Square test, Fisher’s Exact Test, and Odds Ratio (OR) calculations, with a significance level of p < 0.05. The study found an overall mortality rate of 25.3% among ACS patients. A significant relationship was observed between diabetes mellitus and mortality (p = 0.012; OR = 3.1) as well as between kidney disorders and mortality (p = 0.019; OR = 4.0). This indicates that ACS patients with diabetes mellitus have approximately three times higher risk of death, and those with kidney disorders have about four times higher risk compared to those without these comorbidities. In conclusion, diabetes mellitus and kidney disorders are significant predictors of mortality among ACS patients, highlighting the importance of comprehensive management for patients with these conditions in clinical cardiovascular care.
Differences in Neutrophil Lymphocyte Ratio (NLR) between Sepsis and Septic Shock Patients in a Tertiary Hospital in Indonesia Kurniati, Intanri; Arisqan, Ferdian Syukri; Mutiara, Utari Gita
Majalah Kedokteran Bandung Vol 55, No 3 (2023)
Publisher : Faculty of Medicine, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15395/mkb.v55n3.3149

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Sepsis is a severe medical condition characterized by organ dysfunctions resulting from the body's response to an infection. Septic shock is a complication of sepsis that involves circulatory, cellular, and metabolic disturbances. The body's response to infection is typically marked by an increase in neutrophils and a decrease in lymphocytes, leading to increased Neutrophil Lymphocyte Ratio (NLR). This study aimed to investigate the differences in NLR between sepsis and septic shock patients treated at Dr. H. Abdul Moeloek Provincial Hospital, Lampung, Indonesia. This study utilized a comparative analytic study approach with a cross sectional design. A total of 96 sepsis patients who met the inclusion and exclusion criteria treated during the period January 2018 - December 2020 at Dr. H. Abdul Moeloek Provincial Hospital, Lampung, Indonesia, were included in this study. The study found that most of sepsis patients showed an increase in neutrophils (89.58%), a decrease in lymphocytes (94.79%), and elevated NLR values (87.5%). The mean NLR value of septic shock patients (20.10±5.89) was significantly higher than that of sepsis patients (18.01±1.35) (p=0.025). It indicates that the NLR value increases significantly in patients who develop septic shock compared to those with sepsis alone. The findings suggest that NLR could be a potential biomarker for septic shock diagnosis. However, the effectiveness of NLR in predicting the severity of sepsis and determining the risk of mortality in these patients still needs to be examined by conducting studies that involve a larger sample size.
Penyuluhan Kesehatan tentang Peningkatan Pengetahuan Masyarakat RT. 002 Lk. II Kelurahan Karang Maritim Kecamatan Panjang Bandar Lampung Mengenai Hepatitis A Himayani, Rani; Ismunandar, Helmi; Muhartono, Muhartono; Kurniati, Intanri
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 3 No. 1 (2017): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v3i1.2024

Abstract

Hepatitis virus akut merupakan infeksi sistemik yang dominan menyerang hati. Hampir semua kasus hepatitis virus akut disebabkan oleh salah satu dari lima jenis virus, yaitu: virus hepatitis A, virus hepatitis B, virus hepatitis C, virus hepatitis D, dan virus hepatitis E. Indonesia merupakan daerah endemis sedang–tinggi untuk penyakit hepatitis A. Untuk mencegah transmisi dan tindakan terapi dini yang lebih efektif maka diperlukan adanya upaya peningkatan pengetahuan mengenai hepatitis A. Metode yang digunakan dalam kegiatan pengabdian kepada masyarakat ini adalah penyuluhan kesehatan dengan ceramah dan diskusi. Kegiatan ini dihadiri oleh 30 orang peserta yang tinggal di Kelurahan Karang Maritim Kecamatan Panjang. Setelah dilakukan penyuluhan terjadi peningkatan pengetahuan yang didapatkan dari nilai pre test dan post test yaitu 40% menjadi 100%. Simpulan, terjadi peningkatan pengetahuan masyarakat mengenai pengetahuan Hepatitis A di Panjang Bandar Lampung.Kata kunci:Hepatitis, pengetahuan, penyuluhan.
Peningkatan Pengetahuan dan Partisipasi Aktif dalam Gerakan Cegah dan Berantas Skabieske pada Anak-Anak Pondok Pesantren Annida Kecamatan Jatimulyo, Lampung Selatan Wulan, Anggraini Janar; Kurniati, Intanri; Jausal, Anisa Nuraisa
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 4 No. 1 (2019): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v4i1.2529

Abstract

Skabies atau yang dikenal dengan nama kudisan merupakan suatu penyakit kulit menular yang disebabkan oleh parasit Sarcoptes scabei. Penyakit ini sejak tahun 2017 oleh World Health Organization (WHO) dimasukkan dalam kelompok Neglected Tropical Diseases atau NTDs. Jumlah penderita skabies di Indonesia menunjukkan angka yang berbeda di setiap daerah. Jumlah kasus baru penyakit skabies di propinsi Lampung tahun 2011 berdasarkan data Dinas Kesehatan Provinsi Lampung berjumlah 1135 orang dan meningkat lebih dari dua kali lipat menjadi 2941 orang pada tahun 2012. Pondok pesantren adalah salah satu lembaga pendidikan Islam yang identik dengan kepadatan penduduk yang tinggi.Beberapa faktor diketahui berperan sebagai faktor resiko terjadinya skabies. Faktor tersebut antara lain usia muda (5-14 tahun), jumlah penghuni rumah yang padat lebih dari 5 orang, penggunaan barang pribadi secara bersama termasuk tempat tidur, personal higiene dan sanitasi lingkungan yang buruk.Hampir seluruh penelitian mengenai skabies merekomendasikan perlunya tindakan untuk meningkatan pengetahuan masyarakat mengenai penyakit skabies terutama kelompok rentan seperti anak-anak dan remaja yang tinggal secara berkelompok, salah satunya adalah warga pondok pesantren.Khalayak sasaran pada kegiatan ini adalah anak-anak pondok pesantren Annida yang berusia 12-13 tahun, yaitu para santri baru, dan dibatasi untuk 50-75 santri.Tujuan kegiatan ini adalah untuk meningkatkan pengetahuan dan partisipasi aktif para anak-anak pondok pesantren dalam “ Gerakan Cegah Dan Berantas Skabies”.Metode yang diterapkan pada kegiatan ini mencakup: 1) evaluasiawal; 2) penyuluhan; 3) evaluasi proses; 4) evaluasi akhir,dengan materipenyuluhanmengenaiscabies dantineamulaidarietiologi, gejala, kondisi lingkungan maupun perilaku seperti apa yang menyebabkanS. scabieidan jamur untuk hidup dan berkembang biak serta pencegahannya. Pada kegiatan pengabdian ini juga dilakukan demonstrasi cuci tangan WHO. Hasil pengabdian menunjukkan bahwa kegiatan penyuluhan ini dapat meningkatkan pengetahuan para santri di Pondok Pesantren Annida Lampung Selatan tentang skabies. Oleh karena itu, penyuluhan yang kontinu diperlukan untuk peningkatan pengetahuan secara berkelanjutan.Kata kunci: peningkatan pengetahuan, pondok pesantren, skabies
Peningkatan Pengetahuan dan Partisipasi Aktif dalam Gerakan Cegah dan Berantas Skabies kepada Anak-Anak Pondok Pesantren Annida Kecamatan Jatimulyo Lampung Selatan Wulan, Anggraini Janar; Larasati, Ta; Kurniati, Intanri; Jausal, Anisa Nuraisa
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 5 No. 1 (2020): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v5i1.2812

Abstract

Skabies merupakan penyakit kulit menular yang disebabkan oleh Sarcoptes scabei. Angka kejadian skabies berdasarkan penelitian-penelitian di pondok pesantren di Indonesia termasuk Bandar lampung masih tinggi. Faktor utama yang menyebabkan tingginya prevalensi skabies pada tempat hunian yang padat seperti pondok pesantren adalah adanya kontak fisik antar individu yang memudahkan transmisi langsung dari kulit ke kulit. Faktor lain yang mempengaruhi kejadian skabies adalah tingkat pengetahuan, kebersihan pribadi, dan juga faktor resiko berupa usia anak-anak hingga remaja. Oleh karena itu perlu dilakukan kegiatan penyuluhan untuk meningkatkan pengetahuan mengenai skabies dan tindakan untuk mencegahnya. Kegiatan meliputi penyuluhan, demontrasi dan praktek cuci tangan WHO serta pemeriksaan kesehatan kulit dan pengobatannya. Evaluasi meliputi penilaian sebelum, selama, dan sesudah kegiatan. Pada pre test didapatkan 42 peserta (65,62%) belum memiliki pemahaman tentang skabies dengan nilai kurang dari 60, 18 peserta (28,12%) memiliki pemahaman yang cukup tentang skabies dengan rentang nilai 60-79, dan 4 peserta (6,25%) sangat paham terhadap penyakit skabies dengan nilai lebih dari 80. Dari hasil post test didapatkan 6 peserta (9,37%) memiliki pemahaman yang sangat baik dengan rentang nilai 80-100, 39 peserta (60,93%) memiliki pemahaman yang cukup, dan 19 peserta (29,68%) tetap belum memiliki pemahaman mengenai skabies. Evaluasi proses menunjukkan seluruh peserta mampu melakukan cuci tangan WHO dengan benar. Disimpulkan bahwa kegiatan penyuluhan ini dapat meningkatkan pengetahuan para santri mengenai penyakit skabies dan para santri mampu melakukan tindakan pencegahan berupa cuci tangan WHO. Oleh karena itu, penyuluhan yang kontinu diperlukan untuk peningkatan pengetahuan secara berkelanjutan.Kata kunci: pencegahan, pemberantasan, pondok pesantren, skabies
Sosialisasi Kesehatan Reproduksi Pada Ibu-Ibu dengan Metode KIE (Komunikasi, Informasi dan Edukasi) di Kecamatan Baradatu Kabupaten Way Kanan Kurniawaty, Evi; Utama, Winda Trijayanthi; Kurniati, Intanri; Andriani, Silvia
JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Vol. 5 No. 1 (2020): JURNAL PENGABDIAN MASYARAKAT RUWA JURAI
Publisher : FK Unila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jpmrj.v5i1.2825

Abstract

Angka kematian ibu merupakan salah satu indikator keberhasilan pembangunan kesehatan. Masalah kesehatan reproduksi perempuan, termasuk perencanaan kehamilan dan persalinan yang aman secara medis juga harus menjadi perhatian bersama, bukan hanya kaum perempuan saja karena hal ini akan berdampak luas dan menyangkut berbagai aspek kehidupan yang menjadi tolak ukur dalam pelayanan kesehatan. Tujuan dari kegiatan untuk meningkatkan pengetahuan masyarakat khususnya ibu-ibu dalam kesehatan reproduksi. Metode dalam kegiatan yaitu KIE (Komunikasi, Informasi dan Edukasi). Pengabdian masyarakat yaitu pendidikan kesehatan meliputi ceramah atau penyuluhan, Tanya jawab, diskusi dan gambar tentang pengenalan dan tindak lanjut kesehatan reproduksi di tatanan masyarakat. Mayoritas masyarakat yang terlibat dalam pengabdian masyarakat ini adalah perempuan (72%). Rerata usia wanita ±40-50 tahun, wanita usia subur dengan usia ±25-35 tahun sebanyak 57,4%,. Tingkat pengetahuan sebelum dilakukan penyuluhan kesehatan tentang kesehatan reproduksi pada ibu – ibu masih rendah, terdapat peningkatan pengetahuan peserta penyuluhan kesehatan tentang kesehatan reproduksi ibu – ibu setelah dilakukan penyuluhan kesehatan.Kata Kunci: KIE , Kesehatan Reproduksi, Pengabdian Masyarakat
Co-Authors Ade Yonata Ade Yonata, Ade Afifah, Ighra Agustya Tjiptaningrum Agustyas Tjiptaningrum Agustyas Tjiptaningrum Al Farisi, Ahmad Fathin Al Ghifari, Ghaza Ahmad Alyssa Fairudz Shiba Andriani, Silvia Angelia, Tisa Anggraeni Janar Wulan Anggraeni Janar Wulan, Anggraeni Janar Aprilia, Sandrina Audy Ardika, Okta Besti Arif Yudho Prabowo Arisqan, Ferdian Syukri Armadani, Melni Audah, Kholis A. Azhar, Hafidz Sirojudhin Baehaqi Bagus Pratama Bayu Anggileo Pramesona Chanief Hassan Widjaja Chicy WIdya Morfi Dalillah, Fathian Nur Damayanti, Putri Deborah Natasha Dewi Nur Fiana Dian Isti Angraini Diana Mayasari Ety Apriliana Evi Kurniawati Evi Kurniawati, Evi Fadhlurrahman, Fadhlurrahman Febilla Naili Alfalah Ferry Mulyadi Fidha Ramayani Giska Tri Putri Hadibrata, Exsa Helmi Ismunandar Hendri Busman Hilmi, Tamadar Indah Salsabila Indri Windarti Intan Kusumaningtyas Iswandi Darwis Jausal, Anisa Nuraisa Jhons Fatriyadi Suwandi Jonathan Rivaldo Gultom Kamila Salsabila Karima, Nisa Kenos Stefanus Khairun Nisa Kurniawaty, Evi Maharani, Denisa Marcellia, Selvi Muhammad Ricky Ramadhian Muhammad Yusran Muhartono Muhartono Nasution, Salwa Salsabila Ni Made Shanti Novita Carolia Nurrahma, Alya Nabila Nurul Utami Oktadoni Saputra Putri, Morica Angellia Shyama Putri, Najwa Naraniya Putu Ristyaning Ayu Qurani, Istiqomatul rahmawati, selvi Rana Noor Fakhira Siregar Rani Himayani Ratna Dewi Puspita Sari Ratna, Maya Ganda Rengganis Wardani, Dyah Wulan Sumekar Reni Zuraida Risal Wintoko Risti Graharti Rizki Hanriko Rizky Agung Purnomo Roro Rukmi Windi Perdani, Roro Rukmi Salsabila, Kamila Sangging, Putu Ristyaning Ayu Septia Eva Lusina Septiani, Linda Setiawan, Gigih Sinaga, Herman Fransiskus Siti Maharani Suci, Maghfirly Juniarti Eka Suharmanto Suherman, Auriva Renasha Susianti Susianti, Susianti Syazili Mustofa TA Larasati Tibar, Fifi Nurliza Aini Tutik Ernawati Utari Gita Mutiara Vira Katya Aurelia Winda Trijayanthi Utama, Winda Trijayanthi Worocahyo, Avis Meyvika Wulan, Anggraini Janar Yuningrum, Hesti