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Uji Fitokimia Dan Aktivitas Antioksidan Ekstrak Etanol Daun Kelor (Moringa Oleifera) Sudirman, Sudirman; Sulfiani, Sulfiani; Mainassy, Meillisa Carlen; Pramono, Edi
Barongko: Jurnal Ilmu Kesehatan Vol. 3 No. 3 (2025): Barongko : Jurnal Ilmu Kesehatan (Juli)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/bajik.v3i3.777

Abstract

Background: Free radicals play a major role in causing damage to cells and body tissues, which can trigger various degenerative diseases. One preventive strategy is the use of antioxidants. Moringa oleifera leaves are a herb known to be rich in phytochemical compounds with high antioxidant potential. Objective: This study aimed to evaluate the phytochemical content and antioxidant activity of ethanol extract of Moringa leaves as a natural ingredient with potential use in the development of pharmaceutical products or functional foods. Methods: Moringa leaves were extracted using a maceration method with 96% ethanol as a solvent. Phytochemical tests were conducted to identify secondary metabolites such as alkaloids, flavonoids, saponins, tannins, steroids, and terpenoids. Antioxidant activity was analyzed using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, and IC₅₀ values were calculated to determine their antioxidant potential. Results: The ethanol extract of Moringa leaves contained flavonoids, saponins, tannins, and alkaloids. The DPPH test results showed that the extract had an IC₅₀ value of 65.4 µg/mL, which is categorized as moderate antioxidant activity. Conclusion: The ethanol extract of Moringa leaves contains diverse phytochemicals and significant antioxidant activity. This demonstrates the great potential of Moringa leaves as a source of natural antioxidants in the development of herbal medicines and functional food products.
Analisis Peran Tokoh Adat dalam Promosi Kesehatan Masyarakat di Daerah Terpencil Marwono, Marwono; Pannyiwi, Rahmat; Harlina, Harlina; Pramono, Edi; Susanti, Susi
Barongko: Jurnal Ilmu Kesehatan Vol. 3 No. 3 (2025): Barongko : Jurnal Ilmu Kesehatan (Juli)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/bajik.v3i3.788

Abstract

Traditional leaders play a crucial role in the social structure of remote communities, particularly in influencing social behavior and norms, including health behaviors. This study aims to analyze the role of traditional leaders in community health promotion in remote areas. The method used was a descriptive qualitative approach using in-depth interviews with traditional leaders, health workers, and the community in District X. The results indicate that traditional leaders act as facilitators, messengers, and guardians of cultural values, increasing community awareness and acceptance of health programs. The active involvement of traditional leaders has been shown to increase the effectiveness of health promotion, particularly in immunization programs, environmental sanitation, and maternal and child care. It is concluded that integrating the role of traditional leaders into health promotion strategies can be an effective approach to improving community health status in remote areas.
Topical Application Type of Fish Oil Promotes Re-Epithelialization in Burn Wound Healing in Rats Sasongko, Heru; Pitaloka, Nirwana Asri Diah; Kurniawan, Muhammad Rizki; Pramono, Edi; Setyawan, Novan Adi; Rohman, Abdul
Majalah Obat Tradisional Vol 30, No 2 (2025)
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/mot.95644

Abstract

Burns are a condition that is often found in the world in various cases such as accidents. The incidence of burns will probably increase as human activities become more complex. Wounds that are not treated immediately tend to become infected and cause death. Fish oil is one of the ingredients that has been studied for wound healing. Previous research shows that fish oil is rich in long-chain omega-3 fatty acids such as docosahexaenoic acid and eicosapentaenoic acid, which have anti-inflammatory effects. However, there has not been much research on the type of fish oil used and the wound healing process. The aim of this study was to determine the wound-healing activity of milkfish (Chanos chanos Forsskal.), patin (Pangasius djambal), and eel (Anguilla bicolor) fish oil. Tests were carried out on 25 mice as an experimental animal model for burn wounds. Data on percent wound reduction and the re-epithelialization process were statistically calculated using one-way analysis of variance (ANOVA) followed by a post-hoc LSD test. The research results showed that milkfish oil, patin fish oil, and eel fish oil in a concentration of 10% on an ointment basis were able to reduce wounds significantly. Eel fish oil shows the greatest burn wound healing process with re-epithelialization when compared to other oils. The type of fish oil affects the wound healing process.
Memfasilitasi Pelajar KIR (Karya Ilmiah Remaja) Biologi Dengan Kajian Isolasi dan Identifikasi Bakteri Escherichia coli Dari Sampel Kotoran Hewan Ternak Sepanjang SMAN 5 Cilegon Di Laboratorium UPTD Banten Rezaldi, Firman; Cahyono, Andri Tri; Wati, Dyah Rohma; Ginaris, Rifkarosita Putri; Utami, Arti Wahyu; Wijayanti, Fitria Eka Resti; Purbanova, Reni; Nabilla, Jihan; Nurfadhillah, Dea; Faizah, Na’imatul Retno; Nurrahman, Alfina; Oentari, Octavina Dyah; Pramono, Edi; Yudianto, Tri; Sari, Sinta Wisma; Widyaningsih, Ragil; Kustyarini, Farida; Fatchani, Sathi
Jurnal Pengabdian dan Pengembangan Masyarakat Indonesia Vol. 3 No. 2 (2024)
Publisher : Media Publikasi Cendekia Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56303/jppmi.v3i2.275

Abstract

Cemaran bakteri Escherichia .coli merupakan salah satu ancaman bagi setiap daya tahan tubuh makhluk hidup. Menurunnya daya tahan tubuh makhluk hidup disebabkan oleh minimnya kualitas kesehatan yang bersumber pada produk makanan yang tercemar, produk obat yang tercemar, produk kosmetik yang tercemar hingga lingkungan sekitar yang sering tercemar berat. Lingkungan sekitar yang sering tercemar cukup tinggi dan berpeluang besar oleh adanya serangan bakteri Escherichia. coli terdiri atas produk hasil pertanian maupun peternakan yang banyak menimbulkan diare bagi masyarakat yang tidak memiliki imunitas yang kurang stabil. Aktivitas peternakan menjadi salah satu permasalahan dalam mencemari lingkungan adalah kotoran hewan ternak disepanjang SMAN 5 Cilegon. Kotoran hewan ternak disepanjang SMAN 5 Cilegon terdiri dari kotoran hewan ternak ayam, kambing, dan kerbau. Ketiga kotoran hewan ternak tersebut tentunya mengandung bakteri Escherichia coli yang merupakan salah satu bakteri gram negatif penyebab kejadian luar biasa atau KLB yang perlu diberikan suatu pemaparan bagi siswa maupun siswi SMAN 5 Cilegon yang pro aktif dalam mengikuti Karya Ilmiah Remaja (KIR) bidang Biologi untuk meningktakan pengetahuan dan wawasan mengenai keberadaan bakteri E coli yang terdapat di SMAN 5 Cilegon dari tiga kotoran hewan ternak. Pengabdian kepada masyarakat ini adalah bertujuan untuk memfasilitasi siswa maupun siswi yang terlibat dalam kegiatan KIR Biologi untuk memperoleh cara isolasi dan identifikasi bakteri Escherichia coli yang terdapat di sepanjang SMAN 5 Cilegon Banten. Pengabdian kepada masyarakat bekerja sama dengan Laboratorium UPTD Pengujian dan Penerapan Mutu Hasil Perikanan (PPMHP) Provinsi Banten dengan metode yang berlaku. Tahapan kegiatan ini meliputi survey, pra plaksanaan, pelaksanaan, dan evaluasi. responden yang telah teruji berdasarkan hasil pre test mengenai wawasan dan pengetahuan isolasi dan identifikasi bakteri E. coli yang diambil dari tiga sampel kotoran hewan ternak sepanjang SMAN 5 Cilegon. Siswa siswi yang paham sebesar 23% dan 77% adalah komposisi persentase siswa dan siswi yang belum paham mengenai materi isolasi bakteri E. coli dari ketiga sampel kotoran hewan ternak. Sampel kotoran hewan ternak yang terdapat disepanjang SMAN 5 Cilegon seperti kerbau, kambing, dan ayam telah terbukti mengandung bakteri Escherichia coli
PERANCANGAN PEMELIHARAAN POMPA AIR DI KAMPUS POLMAN BABEL MENGGUNAKAN METODE CONDITION-BASED MONITORING Iwan Putra, Nadi; Pramono, Edi; Feriadi, Indra; Rivai, Muhammad
Prosiding Seminar Nasional Inovasi Teknologi Terapan Vol. 4 (2024): Prosiding Seminar Nasional Inovasi Teknologi Terapan
Publisher : Politeknik Manufaktur Negeri Bangka Belitung

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Every time a water pump breaks down on the Polmanbabel Campus, it disrupts the smooth operation and service to employees and students. This project aims to design pump maintenance on the Polmanbabel campus using a condition-based monitoring (CBM) method. The project implementation method is carried out by identifying equipment, selecting condition parameters to be monitored, designing monitoring cards, and testing. The test results show that the monitored pump condition parameters consist of temperature, vibration, pressure, monitoring card instruments can be applied effectively to monitor pump operating conditions.
Meta-Analysis of the Effect of Protected Well and Measles Vaccination on Stunting in Children Under Five Pramono, Edi; Murti, Bhisma; Prasetya, Hanung
Journal of Maternal and Child Health Vol. 9 No. 6 (2024)
Publisher : Masters Program in Public Health, Universitas Sebelas Maret, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26911/thejmch.2024.09.06.03

Abstract

Background: Stunting is a condition where children's growth fails (body and brain growth) due to malnutrition for a long time. The incidence of stunting in toddlers needs special attention because it can hinder children's physical and mental development. This study aims to analyze and estimate the effect of protected wells and the measles vaccine on the incidence of stunting in children under five, with a meta-analysis based on primary studies conducted previously. Subjects and Method: Meta-analysis was carried out in PICO format. Population: Children under five. Intervention: Protected Wells and Measles vaccine status. Comparison: Unprotected Well and Status not vaccinated against measles. Outcome: Stunting incidence. Article searches were carried out using several databases such as Google Scholar, PubMed, Science Direct, and Springerlink. The keywords used are "Protected well" AND Measles vaccine" AND "Stunting in toddlers". Inclusion criteria for the included articles were full-text articles with a cross-sectional design from 2015 to 2023. This study was conducted following PRISMA flow diagram guidelines. Data was analyzed using the Review Manager 5.3 application. Results: 12 cross-sectional studies from Asia and Africa were selected for meta-analysis. the total sample was 48,128 toddlers. Protected well (aOR= 0.86; 95% CI= 0.75 to 1.00; p= 0.040) and measles vaccine (aOR= 0.59; 95% CI= 0.27 to 1.29; p= 0.190) reduce the risk of stunting in children under five. Conclusion: Protected wells and administering the measles vaccine reduce the incidence of stunting in toddlers.
Implementasi Pemahaman Peluang Hukum dan Budaya Adat Desa Pesanggrahan Kota Batu Terhadap Masyarakat Sebagai Icon Pariwisata Asrofi, Asrofi; Maulina Putri, Devita; Pramono, Edi; Nabila Azizah, Kristalia; Wahyu Pravitha, Cattleya; Prasetya, Rizki
Innovative: Journal Of Social Science Research Vol. 4 No. 1 (2024): Innovative: Journal Of Social Science Research
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/innovative.v4i1.7921

Abstract

Di Jawa Timur sangat banyak sumber daya yang perlu untuk di manfaatkan sebagai peningkatan ekonomi dan taraf hidup masyarakat. Kota batu merupakan salah satu kota wisata di Jawa Timur yang memiliki berbagai desa yang memiliki tempat wisata baru setiap tahunnya. Dampak dari tempat wisata ini memberikan peningkatan kesejahteraan bagi masyarakat kota Batu. Salah satunya desa Pesanggrahan yang merupakan desa yang terletak di kecamatan Batu kota Batu provinsi Jawa Timur. Desa ini memiliki letak yang strategis dengan khazanah budaya sebagai peluang besar untuk menjadi icon pariwisata. Selain itu desa Pesanggarahan memiliki potensi dan peluang yang cukup besar, desa ini juga memiliki beberapa permasalahan yang harus dipikirkan. Salah satu permasalahan pada desa ini yakni kurangnya kesadaran masyarakat tentang peluang adat untuk di jadikan icon pariwisata. Sehingga dari permasalahan tersebut menjadi penghambat terwujudnya budaya hukum adat Pesanggarahan sebagai destinasi pariwisata. Tujuan dari kegiatan ini adalah terwujudnya kesadaran masyarakat desa Pesanggerahan tentang icon pariwisata hukum adat yang dapat dijadikan salah satu daya tarik wisatawan. Selain itu dapat menjadi contoh pengenalan budaya atau hukum adat masyarakat desa Pesanggrahan agar di ikuti oleh tempat wisata lainnya khusunya di kota Batu. Langkah ini akan membuat desa Pesanggrahan dikenal sebagai desa pariwisata adat dan memberikan peningkatan pariwisata sehingga meningkatkan kesejahteraan masyarakat pasenggrahan. Dalam upaya mewujudkan tujuan tersebut maka dalam penulisan penelitian ini menggunakan metode kualitatif dengan mencari problematika masalah yang menghambat serta  mencari peluang budaya adat yang dapat dijadikan icon pariwisata yang disajikan dalam bentuk naratif. Hasil dari audiensi dengan pemerintah desa dan perwakilan masyarakat desa Pesanggrahan untuk meminta pandangan terkait icon budaya dan adat yang berpeluang untuk menjadi pariwisata. Kemudian melakukan sosialisasi terhadap Masyarakat dan karang taruna desa Pesanggrahan, berkerja sama dengan mitra sampai monitoring kegiatan yang dapat menunjang terwujudnya pariwisata budaya dan adat.
Synthesis and Characterization of Copoly(Anethole-Stearyl Acrylate) as Phenol Adsorbent Handayani, Desi Suci; Pramono, Edi; Dewi, Anita Kusuma
Jurnal Kimia Valensi Jurnal Kimia VALENSI, Volume 11, No. 2, November 2025
Publisher : Department of Chemistry, Faculty of Science and Technology Syarif Hidayatullah Jakarta State Islamic University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/jkv.v11i2.46484

Abstract

This study aims to synthesize copoly (Anethole-stearyl acrylate, SA) through cationic polymerization at room temperature (28–36°C) under a nitrogen atmosphere. The synthesis was carried out without a solvent using BF3O(C2H5)2 as the initiator. SA was added in varying weights of 2%, 4%, and 6% relative to anethole. The product obtained from the synthesis was then applied as a phenol adsorbent using the batch method at different contact times. FTIR (Fourier Transform Infrared) analysis showed that methoxy group (-OCH3) termination occurred at wavenumber 1147 cm-1, followed by the loss of vinyl group (C=C) at 1633–1654 cm-1. In addition, the loss of =C-H vinyl bending and stretching group absorption occurred at 964–998 cm-1 and 3025–3095 cm-1, respectively. Structural analysis using 1H-NMR showed the loss of the vinyl group proton signal at a chemical shift (δH) of 5.8–39 ppm. The addition of 2%, 4%, and 6% SA led to an increase in intrinsic viscosity of 26.891, 41.093, and 55.336, respectively. The morphology of copoly showed the presence of various cavities. The degradation temperature of the product increased with the addition of SA. During the application of copoly as a phenol adsorbent, the 6% (w/w) concentration had the largest adsorption capacity of 2.22 mg/g.
The Initial Screening of Heavy Metal Adsorption on Highly Porous Metal-Organic Frameworks based on MIL-101(Cr), Ethylenediamine-modified MIL-101(Cr), and MIL-101(Cr)-NH2 Dendy, Dendy; Lestari, Witri Wahyu; Anshori, Isa; Rahardjo, Sentot Budi; Pramono, Edi; Saraswati, Teguh Endah; Wibowo, Fajar Rakhman
Molekul Vol 21 No 1 (2026)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2026.21.1.17186

Abstract

ABSTRACT. Heavy metal pollution is a significant environmental issue with detrimental effects on ecosystem and human health. Therefore, comprehensive handling need to be carried out. Herein we studied initial screening adsorption of heavy metals including Ni, Cu, Zn, Cd, and Pb using Metal-Organic Frameworks class of Materials Institute Lavoisier (MIL) based on Cr(III). MIL-101(Cr), and its modification with ethylenediamine (EA), and MIL-101(Cr)-NH2 were prepared under hydrothermal condition. X-ray diffraction and FT-IR analysis confirmed the formation of the targeted materials. A new absorption band at 1050 cm-1 corresponds to vibration of C-N which indicates the successful EA modification into MIL-101(Cr). Nitrogen sorption isotherm measurement revealed MIL-101(Cr) and EA@MIL-101(Cr) have a specific surface area of 2548.6 and 2079 m²/g with micropore-sized, while MIL-101(Cr)-NH2 has a specific surface area of 1583.4 m²/g with micro and mesopore-sized. Adsorption performance was assessed through batch experiments monitored by atomic absorption spectroscopy. The results show that MIL-101(Cr) and its modification with EA exhibit higher adsorption capacities on cadmium and nickel metal ions, compared to MIL-101(Cr)-NH2. Meanwhile, MIL-101(Cr)-NH2 and MIL-101(Cr) show more dominant adsorption capabilities on zinc and copper ions compared to the EA-modified MIL-101(Cr). This result suggests that the material's porosity still plays a dominant role in the adsorption processes compared to amine functionalize group on MIL itself. Keywords: adsorption, chromium(III), heavy metals, MOF, MIL
Co-Authors Abdul Basith Abdul Rohman Alfina Nurrahman Anisya Lisdiana, Anisya Anwari, Nelly Safitri Ari Handono Ramelan Arti Wahyu Utami Asrofi, Asrofi Aswin, Fajar Ayuni Dita Rosalia, Ayuni Dita Bhisma Murti Cahyono, Andri Tri Candra Purnawan Dea Nurfadhillah Dendy, Dendy Desi Suci Handayani Devita Maulina Putri, Devita Maulina Dewi, Anita Kusuma Dian Maruto Widjonarko Dyah Rohma Wati Eko Sulistiyono, Eko Erick Rian Yulianto Erni Suminar Eyastuti Azis Faizah, Na’imatul Retno Fajar Rakhman Wibowo Faradilla, Radianita Fatchani, Sathi Feriadi, Indra Florentinus Firdiyono Gumilar, Roni Hari Hidayatullah, Hari Harlina Harlina Heru Sasongko Isa Anshori Iwan Putra, Nadi Jati Wulansari, Jati Jusdijachlan, R. Kamaruddin, Muh. Ihsan Komar Priatna, Deden Kustyarini, Farida Lestar, Witri Wahyu Lestari, Witri Wahyu M Riva’i Marwono Marwono Meillisa C. Mainassy Melina, Dika Caesar Muhammad Rivai Muhammad Rizki Kurniawan, Muhammad Rizki Nabila Azizah, Kristalia Nabilla, Jihan Nahdiya Sabrina Nashrulloh, Dewi Naufal, Widyan Muhammad Novan Adi Setyawan Novika Tusta Felandi, Novika Tusta Nur Jannah Asrilya, Nur Jannah Oentari, Octavina Dyah Pannyiwi, Rahmat Patiha Patiha, Patiha Pertiwi, Ulvi Dwi Pitaloka, Nirwana Asri Diah Prasetya, Hanung Purbanova, Reni Putra, Nadi Iwan Rahayu Rahayu Rahmad, Sukardi Sugeng Rais Nur Latifah Rifkarosita Putri Ginaris Rizki Prasetya Roro Ernia Rosid Eka Mustofa, Rosid Eka RR. Ella Evrita Hestiandari Rusnita, Rusnita Safitri, Widiya Nur SAHABUDDIN SAHABUDDIN Sari, Sinta Wisma Sayekti Wahyuningsih Sentot Budi Rahardjo Sentot Budi Raharjo Setiyono Setiyono Simanjuntak, Glory Gelarich Sudirman Sulfiani, Sulfiani Susi Susanti Teguh Endah Saraswati Tenriawi, Westy Trisnawati, Desi Venny, Venny Wahyu Pravitha, Cattleya Widyaningsih, Ragil Wijayanti, Fitria Eka Resti Wotok, Nobertus Wuli Wulandari, Resa Yenny, Ratna Fitry Yermi, Yermi Yudianto, Tri Yuniawan Hidayat Zetadini, Reza