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Pengaruh Strategi Lean Management Terhadap Efisiensi Pengelolaan Obat Di Instalasi Farmasi Rumah Sakit Pramono, Edi; Fahamsya, Arifina; Awaluddin, Achmad Indra; Surya, Sara; Pannyiwi, Rahmat
Barongko: Jurnal Ilmu Kesehatan Vol. 4 No. 2 (2026): Barongko : Jurnal Ilmu Kesehatan (Maret)
Publisher : Asosiasi Guru dan Dosen Seluruh Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59585/bajik.v4i2.1004

Abstract

Background: Efficient medication management is a critical factor in hospital pharmacy services. Many hospitals face challenges in controlling medication inventory, service times, and operational costs. Lean Management strategies offer an approach to increasing efficiency by eliminating waste, improving workflows, and optimizing resources. Objective: This study aims to analyze the effect of implementing a Lean Management strategy on medication management efficiency in a hospital pharmacy. Methods: This study used a quasi-experimental design with a pre-test and post-test approach. The sample consisted of the pharmacy department of one hospital implementing Lean Management, with efficiency measurements taken before and after the strategy implementation. Data were analyzed using a paired t-test to compare average medication management time, dead stock levels, and operational costs. Results: The implementation of Lean Management was proven to reduce the average medication management time from 12.5 hours to 8.2 hours per batch (p < 0.05), reduce dead stock by 15%, and reduce operational costs by 10%. Conclusion: The Lean Management strategy significantly improved medication management efficiency in the hospital pharmacy. Recommendations for ongoing implementation and staff training are needed to maintain optimal results.
The Effect of Fe Pillaring and Mg Intercalating into Bentonite Structure Widjonarko, Dian Maruto; Pramono, Edi; Rahardjo, Sentot Budi; Wahyuningsih, Sayekti; Saraswati, Teguh Endah
Jurnal Kimia Sains dan Aplikasi Vol 29, No 2 (2026): Volume 29 Issue 2 Year 2026
Publisher : Chemistry Department, Faculty of Sciences and Mathematics, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jksa.29.2.101-110

Abstract

Bentonite clay particles, measuring less than 2 μm, comprise stacked layers of tetrahedral and octahedral units in a 2:1 configuration (T-O-T). These negatively charged layers were subsequently neutralized with cations. However, the exchange or modification of the cation affects its structure and properties. This study investigates the effect of Fe-ion pillaring on the bentonite layer and the intercalation of Mg ions into Fe-pillared bentonite via ion exchange. The materials were characterized using Scanning Electron Microscopy with Energy Dispersive X-ray Spectroscopy (SEM–EDX) to observe surface morphology and elemental composition, Particle Size Analyzer (PSA) to observe average size and size distribution of particle, Fourier-Transform Infrared Spectroscopy (FTIR) to identify the active site and layer structure, and X-ray Diffraction (XRD) to determine their structural and compositional changes. The results confirm the pillaring treatment effect on a higher average particle size of 469.3 nm, with a polydispersity index (PDI) of 0.495, compared to natural bentonite (414.8 nm and 0.586 nm, respectively). Meanwhile, the intercalating treatment showed a lower average particle size of 433.4 nm and a PDI value of 0.613. FTIR identified the silanol and siloxane functional groups, as well as the aluminosilicate layer. Pillaring by Fe2O3 increased the basal spacing of bentonite from 13.6 Å to 17.35 Å, as indicated by the shift of characteristic bentonite peaks to lower 2θ angles. However, intercalation by MgO into Fe-pillared bentonite actually slightly decreased the basal spacing to 15.16 Å. Meanwhile, Mg intercalation occurred within the interlayer of the aluminosilicate layer, resulting in a peak shift toward higher 2θ angles and an increase in crystallinity to 58.924%, compared with Fe-pillared bentonite (45.376%). This phenomenon is likely related to the presence of the Mg metal intercalant, which has basic properties and can attract the aluminosilicate sheets.
Chemical Study of Mordanting and Fixation Processes in Indigo, Sappanwood, and Tannin Natural Dyes Using Visual and UV-Vis Spectroscopic Analysis Wahyuningsih, Sayekti; Rahmawati, Rahmawati; Djuminah , Djuminah; Murni, Sri; Rosyad, Nisaul Hasanah Abdul; Saraswati, Teguh Endah; Pramono, Edi; Naufal, Widyan Muhammad; Azizah, Isna Nurmilatul; Apriliyani, Rizqi; Salsabila, Nadia Octaviani Faiq
G-Tech: Jurnal Teknologi Terapan Vol 10 No 2 (2026): G-Tech, Vol. 10 No. 2 April 2026
Publisher : Universitas Islam Raden Rahmat, Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70609/g-tech.v10i2.9165

Abstract

Ecoprint is an eco-friendly textile dyeing technique whose color quality is strongly influenced by mordanting and fixation processes. However, inconsistent mordant–fixative systems often result in unstable color intensity and poor standardization. This study aimed to evaluate the effect of different mordant and fixative combinations on the color characteristics of ecoprint fabrics dyed with indigo (Indigofera tinctoria), sappanwood (Caesalpinia sappan), and tannin extracts. Cotton fabrics were treated with either conventional mordant or color mordant, followed by fixation using vinegar, bone lime, lime, clear ferrous sulphate, or ferrous sulphate. Color properties were analyzed using UV-Vis spectroscopy (200-800 nm) and RGB evaluation. Iron-containing mordant systems significantly enhanced absorbance intensity in the visible region. It reduced the RGB lightness values, indicating deeper, more stable colors. Indigo showed maximum absorption at 647-672 nm, with the darkest blue obtained with the color mordant combined with ferrous sulphate fixation. Sappanwood showed maximum absorbance in the 482-491 nm range, under iron-assisted treatments. Tannin dyeing produced the most pronounced darkening effect due to tannin–iron complex formation. Overall, iron-assisted mordant–fixative systems under controlled pH conditions provided the most optimal and reproducible color performance, offering a scientific basis for standardizing the ecoprint process in sustainable textile production.
The Initial Screening of Heavy Metal Adsorption on Highly Porous Metal-Organic Frameworks based on MIL-101(Cr), Ethylenediamine-modified MIL-101(Cr), and MIL-101(Cr)-NH2 Dendy, Dendy; Lestari, Witri Wahyu; Anshori, Isa; Rahardjo, Sentot Budi; Pramono, Edi; Saraswati, Teguh Endah; Wibowo, Fajar Rakhman
Molekul Vol 21 No 1 (2026)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2026.21.1.17186

Abstract

ABSTRACT. Heavy metal pollution is a significant environmental issue with detrimental effects on ecosystem and human health. Therefore, comprehensive handling need to be carried out. Herein we studied initial screening adsorption of heavy metals including Ni, Cu, Zn, Cd, and Pb using Metal-Organic Frameworks class of Materials Institute Lavoisier (MIL) based on Cr(III). MIL-101(Cr), and its modification with ethylenediamine (EA), and MIL-101(Cr)-NH2 were prepared under hydrothermal condition. X-ray diffraction and FT-IR analysis confirmed the formation of the targeted materials. A new absorption band at 1050 cm-1 corresponds to vibration of C-N which indicates the successful EA modification into MIL-101(Cr). Nitrogen sorption isotherm measurement revealed MIL-101(Cr) and EA@MIL-101(Cr) have a specific surface area of 2548.6 and 2079 m²/g with micropore-sized, while MIL-101(Cr)-NH2 has a specific surface area of 1583.4 m²/g with micro and mesopore-sized. Adsorption performance was assessed through batch experiments monitored by atomic absorption spectroscopy. The results show that MIL-101(Cr) and its modification with EA exhibit higher adsorption capacities on cadmium and nickel metal ions, compared to MIL-101(Cr)-NH2. Meanwhile, MIL-101(Cr)-NH2 and MIL-101(Cr) show more dominant adsorption capabilities on zinc and copper ions compared to the EA-modified MIL-101(Cr). This result suggests that the material's porosity still plays a dominant role in the adsorption processes compared to amine functionalize group on MIL itself. Keywords: adsorption, chromium(III), heavy metals, MOF, MIL
Utilization of α-Keratin of Chicken Feathers as Adsorben of Lead Ion Latifah, Rais Nur; Ernia, Roro; Pramono, Edi
ALCHEMY Jurnal Penelitian Kimia Vol 10, No 1 (2014): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.10.1.13.11-21

Abstract

Research of Pb ions adsorption with chicken feathers adsorbent has been conducted. This research aims to determine adsorption properties of activated chicken feathers and the chicken feathers that were not activatedby Na2S for Pb ions. The adsorption process was conducted by batch method with variation of the concentration, pH, and contact time. Pb content in solution is characterized by AAS spectroscopy (Atomic Absorption Spectroscopy). The results show that the contact time and pH condition for adsorption equilibrium are 60 min for activated chicken feathers and 90 min for chicken feathers which were not activated by Na2S at pH 8. Pb absorption by chicken feathers follows Freundlich isotherm and the reaction kinetics follow the Ho equation.
Pengaruh Bentonit terhadap Pembentukan Fasa Polimorf dan Sifat Termal Membran Hibrida Poliviniliden Fluorida/Bentonit Pramono, Edi; Mustofa, Rosid Eka; Saputra, Ozi Adi; Nugroho, Yulianto Adi; Wahyunigrum, Deana; Radiman, Cynthia Linaya; Wahyuningsih, Sayekti; Saraswati, Teguh Endah; Rahardjo, Sentot Budi; Lestari, Witri Wahyu; Widjonarko, Dian Maruto; Ramelan, Ari Handono
ALCHEMY Jurnal Penelitian Kimia Vol 17, No 2 (2021): September
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.17.2.46136.177-184

Abstract

Kajian struktur dan degradasi termal pada membran hibrida poliviniliden fluorida (PVDF)/lempung bentonit (BNT) telah dilakukan. Penelitian ini bertujuan mengetahui pengaruh penambahan BNT terhadap pembentukan fasa PVDF dan sifat termalnya. Membran hibrida PVDF/lempung BNT dibuat dengan metode inversi fasa. Membran yang dihasilkan dikarakterisasi dengan attenuated total reflectance fourier transform infrared (ATR-FTIR), x-ray diffraction (XRD), dan differential scanning calorimetry (DSC). Hasil penelitian menunjukkan membran PVDF/BNT memiliki struktur polimorf PVDF fasa α dan β yang terkonfirmasi dari data FTIR dan XRD. Data DSC menunjukkan penurunan nilai titik leleh (Tm) dengan penambahan BNT, dan dengan rentang suhu pelelehan yang lebih kecil. Kristalisasi PVDF terjadi secara isothermal dan adanya BNT menghasilkan titik kristalisasi (Tc) pada suhu yang lebih tinggi dibandingkan membran PVDF murni. Analisis termal dengan DSC memberikan informasi komprehensif pelelehan dan kristalisasi dari polimorf PVDF pada matriks membran.Effect of Bentonite toward Polymorph Phase Formation and Thermal Properties of Polyvinylidene Fluoride/Bentonite Hybrid Membranes. The study of the structure and thermal properties of PVDF/bentonite (BNT) hybrid membranes has been carried out. This study aims to determine the effect of BNT addition on the phase formation and thermal properties of the PVDF. In this study, PVDF/BNT hybrid membranes were prepared through the phase inversion method. The resulting membrane was characterized by Attenuated Total Reflectance Fourier Transform Infrared (ATR-FTIR), x-ray diffraction (XRD), and differential scanning calorimetry (DSC). The results showed that the PVDF/BNT membrane has a PVDF polymorph structure with α and β phases confirmed by FTIR and XRD data. The DSC data showed that the addition of BNT decrease of the melting point (Tm) and with a smaller melting temperature range. PVDF polymorph crystallization occurs isothermally and the presence of BNT produces a crystallization point (Tc) at a higher temperature than pristine PVDF membrane. Thermal analysis with DSC provides comprehensive information on melting and crystallization of PVDF polymorphs in the membrane matrix.
Sintesis Kopoli(Anetol-Stearil Akrilat-Divinilbenzena) sebagai Material Alternatif Adsorben Handayani, Desi Suci; Pramono, Edi; Suwaji, Bagus Indra
ALCHEMY Jurnal Penelitian Kimia Vol 20, No 1 (2024): March
Publisher : UNIVERSITAS SEBELAS MARET (UNS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/alchemy.20.1.77588.82-97

Abstract

Sintesis kopoli(Anetol-Stearil Akrilat-Divinilbenzena) atau KASA-DVB berhasil dilakukan melalui reaksi kopolimerisasi kationik menggunakan inisiator BF3O(C2H5)2 dan Stearil Akrilat (SA) dengan variasi 2, 4, dan 6 (b/b), pada jumlah anetol dan DVB tetap. Produk yang dihasilkan dikarakterisasi gugus fungsi, struktur, morfologi, viskositas intrinsik dan sifat termalnya berturut-turut menggunakan spektroskopi Fourier-transform infrared (FT-IR), proton nuclear magnetic resonance (1H-NMR), scanning electron microscopy dengan energy dispersive X-ray (SEM-EDX), viskometer Ostwald dan analisis thermogravimetric-differential thermal-differential scanning calorimetry (TG/DTA-DSC). Uji kinerja adsorpsi senyawa dilakukan dengan metode batch dan konsentrasi adsorbat ditentukan dengan Spektrofotometer UV-Vis. Data FT-IR menunjukkan hilangnya serapan gugus alil dan vinil sementara data 1H-NMR menunjukkan hilangnya H-alil dan H-vinil yang mengindikasikan KASA-DVB berhasil disintesis. Penambahan konsentrasi SA dapat meningkatkan nilai viskositas intrinsik. Analisis morfologi KASA-DVB diperoleh padatan dengan permukaan yang relatif kasar dan jumlah rongga semakin sedikit. Analisis termogram TG/DTA-DSC menunjukkan penurunan sifat termal yaitu diperoleh titik inisiasi degradasi massa yang lebih rendah. Nilai kapasitas adsorpsi tertinggi diperoleh dari hasil uji kinerja adsorpsi pada waktu kontak ke-60 menit dan variasi berat SA 2%. Berdasarkan data kinerja adsorpsi, menunjukkan bahwa KASA-DVB memiliki potensi sebagai adsorben. Uji adsorpsi menunjukkan kapasitas adsorpsi terbesar adalah 23,22 (mg/g) pada KASA-DVB 2%. Synthesis of Copoly(Anethol-Styryl Acrylate-Divinylbenzene) as an Alternative Adsorbent Material. Synthesis of copoly(Anethole-Stearyl Acrylate-Divinylbenzene) or KASA-DVB was successfully carried out by a cationic copolymerization reaction using BF3O(C2H5)2 initiator and various concentrations of Stearyl Acrylate (SA) are 2, 4, and 6 wt. The resulting products were characterized by functional groups, structure, morphology, intrinsic viscosity, and thermal properties using Fourier-transform infrared spectroscopy (FT-IR), proton nuclear magnetic resonance spectroscopy (1H-NMR), scanning electron microscopy with energy dispersive X-ray spectroscopy (SEM-EDX), Ostwald Viscometer, and thermogravimetric-differential thermal-differential scanning calorimetry analysis (TG/DTA-DSC), respectively. The adsorption performance was analyzed using the batch method, and the adsorbate concentration was determined using a UV-Vis spectrophotometer. The FT-IR data showed loss of allyl and vinyl groups absorption, while 1H-NMR data showed loss of H-allyl and H-vinyl, indicating that KASA-DVB was successfully synthesized. The increase in SA concentration can increase the intrinsic viscosity value. Morphological analysis of KASA-DVB obtained solid materials with a relatively rough surface and fewer cavities. Thermogram analysis of TG/DTA-DSC showed a decrease in thermal properties, which was a lower mass degradation initiation point. The highest adsorption capacity was obtained from the adsorption performance with a contact time of 60 minutes and 2% SA weight variation. The adsorption performance data shows that KASA-DVB is potent as an adsorbent. The adsorption showed that the largest adsorption capacity was 23.22 (mg/g) on KASA-DVB 2%.
Co-Authors Abdul Basith Abdul Rohman Anisya Lisdiana, Anisya Anwari, Nelly Safitri Apriliyani, Rizqi Ari Handono Ramelan Aripa, Lusyana Arti Wahyu Utami Asrofi, Asrofi Aswin, Fajar Awaluddin, Achmad Indra Ayuni Dita Rosalia, Ayuni Dita Azizah, Isna Nurmilatul Bahrun, Suriani Bhisma Murti Cahyono, Andri Tri Candra Purnawan Cynthia Linaya Radiman Darwis, Amelia Dea Nurfadhillah Dendy, Dendy Desi Suci Handayani Devita Maulina Putri, Devita Maulina Dewi, Anita Kusuma Dian Maruto Widjonarko Djuminah , Djuminah Dyah Rohma Wati Eka Setiawati Eko Sulistiyono, Eko Erick Rian Yulianto Erni Suminar Eyastuti Azis Fahamsya, Arifina Faizah, Na’imatul Retno Fajar Rakhman Wibowo Faradilla, Radianita Fatchani, Sathi Feriadi, Indra Florentinus Firdiyono Gumilar, Roni Hari Hidayatullah, Hari Harlina Harlina Heru Sasongko Isa Anshori Iwan Putra, Nadi Jati Wulansari, Jati Jusdijachlan, R. Kamaruddin, Muh. Ihsan Komar Priatna, Deden Kustyarini, Farida Lestar, Witri Wahyu Lestari, Witri Wahyu M Riva’i Marwono Marwono Meillisa C. Mainassy Melina, Dika Caesar Muhammad Rivai Muhammad Rizki Kurniawan, Muhammad Rizki Nabila Azizah, Kristalia Nabilla, Jihan Nahdiya Sabrina Nashrulloh, Dewi Naufal, Widyan Muhammad Novan Adi Setyawan Novika Tusta Felandi, Novika Tusta Nugroho, Yulianto Adi Nur Jannah Asrilya, Nur Jannah Nurhaedah Nurhaedah Nurrahman, Alfina Oentari, Octavina Dyah Ozi Adi Saputra, Ozi Adi Pannyiwi, Rahmat Patiha Patiha, Patiha Pertiwi, Ulvi Dwi Pitaloka, Nirwana Asri Diah Prasetya, Hanung Purbanova, Reni Putra, Nadi Iwan Rahayu Rahayu Rahmad, Sukardi Sugeng Rahmat, Rezqiqah Aulia Rahmawati, Rahmawati Rais Nur Latifah Rifkarosita Putri Ginaris Rizki Prasetya Roro Ernia Rosid Eka Mustofa, Rosid Eka Rosyad, Nisaul Hasanah Abdul RR. Ella Evrita Hestiandari Rusnita, Rusnita Safitri, Widiya Nur SAHABUDDIN SAHABUDDIN Salsabila, Nadia Octaviani Faiq Sari, Sinta Wisma Sayekti Wahyuningsih Sentot Budi Rahardjo Sentot Budi Raharjo Setiyono Setiyono Simanjuntak, Glory Gelarich Simatupang, Rumiris Sri Murni Sudirman Sulfiani, Sulfiani Surya, Sara Susi Susanti Suwaji, Bagus Indra Teguh Endah Saraswati Tenriawi, Westy Trisnawati, Desi Venny, Venny Wahyu Pravitha, Cattleya Wahyunigrum, Deana Wati, Isra Widyaningsih, Ragil Wijayanti, Fitria Eka Resti Wotok, Nobertus Wuli Wulandari, Resa Yenny, Ratna Fitry Yermi, Yermi Yudianto, Tri Yuniawan Hidayat Zetadini, Reza