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All Journal BALI MEDICAL JOURNAL (BMJ) Medicina journal of internal medicine INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES E-Jurnal Medika Udayana Majalah Ilmiah Fisioterapi Indonesia E-Jurnal Udayana Medica WMJ (Warmadewa Medical Journal) The Indonesian Biomedical Journal ISM (Intisari Sains Medis) : Jurnal Kedokteran Bioscientia Medicina : Journal of Biomedicine and Translational Research Indonesian Journal of Clinical Pathology and Medical Laboratory (IJCPML) International Journal of Nasopharyngeal Carcinoma PREPOTIF : Jurnal Kesehatan Masyarakat Bioscientia Medicina : Journal of Biomedicine and Translational Research Warmadewa Minesterium Medical Journal Journal of Global Pharma Technology Seminar Ilmiah Nasional Teknologi, Sains, dan Sosial Humaniora (SINTESA) Physical Therapy Journal of Indonesia Biosaintifika: Journal of Biology & Biology Education
I Wayan Putu Sutirta Yasa
Bagian Patologi Klinik Fakultas Kedokteran Universitas Udayana
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Computer Science & IT Decision Sciences, Operations Research & Management Education Health Professions Immunology & microbiology Library & Information Science Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences

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THROMBOCYTOPENIA IN DENGUE HAEMORRHAGIC FEVER Sutirta-Yasa, I Wayan Putu; Tirta Putra, Gede Agus Eka; Rahmawati, Ana
Medicina Vol 43 No 2 (2012): Mei 2012
Publisher : Medicina

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Abstract

The incidence and geographical distribution of dengue has gradually increased during the past decade. Today, dengue is considered one of the most important arthropod-borne viral diseasases in humans in term of morbidity and mortality. Dengue infection   a potential life-threatening dengue hemorrhagic fever (DHF) / dengue shock syndrome(DSS), characterized by thrombocytopenia and increased vascular permiability. Thrombocytopenia causes bleeding, but in   DHF patients with thrombocytopenia do not always develop bleeding manifestation. The pathogenesis of thrombocytopenia are not cleared. Multiple factors  may be involved in the machanisms leading to thrombocytopenia in DHF/DSS patients.
HUBUNGAN JUMLAH SEL LIMFOSIT T CD8+ PADA ULKUS KAKI DIABETIK DERAJAT 3, 4, 5 DAN ULKUS NON DIABETIK Putu Sutirta Yasa, I Wayan; Sudewa Djelantik, Anak Agung Gde; Suastika, Ketut; Mantik Astawa, Nyoma; Yuatmadja, Ignatius Ferdi
journal of internal medicine Vol. 10, No. 1 Januari 2009
Publisher : journal of internal medicine

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Abstract

Diabetes mellitus (DM) is a complex metabolism disorder characterized by a severe chronic hyperglycemia with a largenumber of complications, diabetic foot ulcer (DF) is one of its disastrous progressive complication. It can cause a significantmorbidity if not treated adequately. Diabetic foot ulcer is very difficult to heal as it is generally associated with other co-morbidities,such as vassal complications (peripheral vassal disease) that may cause ischemia sufficient to damage many tissues in thebody. The excess of free radical products induces widespread inflammatory reactions. These conditions may also be exacerbatedby neuropathy and foot injury which directly cause the formation of DF. If the process is followed by infection, the inflammatoryreaction will be more severe. All these events will disrupt the normal immune response to participate in wound healing process.This cross sectional study was performed to determine CD8+ T lymphocyte count in diabetic foot ulcer graded 3, 4, and 5based on Wagner Ulcer Classification System (1989) and to test the hypothesis that CD8+ T cells count in DF grade 3, 4, and 5 islower than non-DM ulcer. As many as 11 patients with DF grade 3, 10 patients with grade 4, 7 patients with grade 5 were includedin this study. Sixteen patients with non-DM ulcer as control group. Red pea-shaped fresh ulcer tissues of lower extremity werecollected from each group for CD8+ T cell lymphocyte count and 2 cc blood were collected from vein for blood glucose examination.The result showed that CD8+ T cell count consistently decreased along with the increase of DF grade. The greatest countwas observed in non-DM ulcer {26/10 field view (10 fv)}, followed respectively by grade 3 (12/10 fv), 4 (8/10 fv), and 5 (6/10fv). Statistical analysis showed the difference in CD8+ T cell count among diabetic foot ulcer groups and foot ulcer non diabeticwas highly significant (p<0.05). The relationship between CD8+ T cell lymphocyte count among groups (Non-DM ulcer, DFgrade 3, 4, 5) based on Spearman Correlation test was 0.84 for CD8+ T cell lymphocyte (r = -0,846, p<0.001).
POLA JUMLAH TROMBOSIT PENDERITA DEMAM BERDARAH DENGUE (DBD) PADA ANAK-ANAK YANG PETANDA SEROLOGINYA POSITIF Ngurah Subawa, Anak Agung; Sutirta Yasa, I Wayan Putu
journal of internal medicine Vol. 8, No. 3 September 2007
Publisher : journal of internal medicine

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Abstract

Thrombocytopenia represent one of non specific laboratory criterion to uphold diagnosed DHF specifiedby WHO. Existence of trombositopenia on third or fourth days of disease, will be easily diagnosed of DHF. Toknow the pattern of the thrombocyte amount on children suffering from DHF based on IgG and IgM serologicmarker. This Research is retrospective study by seeing medical report of pediatric patient which is taken care byDHF in Sanglah Hospital Denpasar from July 2005 until June 2006. There are 42 pediatric patient sufferingfrom DHF with the positive serologi examination result, as much 17 child (40.5%) by IgG is positive, 9 child(21.4%) IgM positive and 16 child (38.1%) by IgG and IgM positive. At fourth days of disease development,the mean of the thrombocyte amount in serologi IgG are positive is the lowest (99.8 x 103/mm3). At fifth days,the mean of thrombocyte amount in serologic IgG and IgM are positive is the lowest (61.7 x 103/mm3). At sixthdays, the mean thrombocyte amount in serologic IgG are positive is the lowest (61.9 x 103/mm3). At seventhdays, the patient having positive IgG or positive IgG and IgM, the mean of the thrombocyte amount experienceof the improvement from previous day. At eighth days, patient having positive IgG and IgM were more oftenhave the thrombocyte amount more than the other (only IgG or IgM positive). The patient suffering from secondinfection (IgG positive or IgG and IgM positive) at the acute phase more often have the thrombocyte amount islower the than the primary infection (IgM Positive). Expected of continuation research with the sample amountand scope is more than before.
HUBUNGAN POSITIF ANTARA ULKUS KAKI DIABETIK DENGAN PERSENTASE SEL BERMARKAH CD4+ PEMBAWA MALONDIALDEHID Putu SutirtaYasa, I Wayan; Suastika, Ketut; Sudewa Djelantik, Anak AgungGede; Mantik Astawa, I Nyoman
INDONESIAN JOURNAL OF BIOMEDICAL SCIENCES Vol. 3, No. 1 Januari 2009
Publisher : Udayana University

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Abstract

Tingginya angka kejadian ulkus kaki diabetik (UKD) dan luka di kaki yangsulit sembuh memberi petunjuk kemungkinan ada proses kematian sel imun yangsangat banyak dan belum jelas mekanismenya secara molekuler pada jaringan UKD.Telah diteliti hubungan antara derajat UKD dengan persentase sel bermarkahCD4+ pembawa malondialdehid (MDA). Penelitian ini adalah penelitianobservasional dengan rancangan cross sectional analytic study yang dilakukan diRumah Sakit pemerintah dan swasta di Denpasar, Badung, Tabanan, dan Gianyar.Parameter yang diukur dari bahan darah adalah kadar gula darah memakai metodeenzimatik (heksokinase), dan dari bahan jaringan kaki, dihitung sel bermarkah CD4+pembawa MDA memakai metode imunohistokimia (reagen dari Biodesign danAbcam ). Dari 80 sampel UKD didapatkan 49 (61,2%) penderita laki-laki dan 31(38.8%) penderita wanita, berdasarkan tingkat keparahan UKD, sampel dipilah lagimenjadi: 29 (31,9%) derajat 2; 20 (21,9%) derajat 3; 13 (14,3%) derjat 4; dan18(19,8%) derajat 5, rata-rata persentase sel bermarkah CD4+MDA adalah 75,0 ±20,5 %, Didapatkan korelasi positif kuat antara persentase sel bermarkah CD4+pembawa malondialdehid dengan derajat UKD (r = 0,71; p < 0,01). Pada penelitianini membuktikan ada mekanisme kematian sel imun dan sekaligus menjawabpermasalahan bahwa pada penderita UKD mudah terkena infeksi dan sulit untukdisembuhkan, dengan dibuktikan bahwa ada korelasi positif kuat antara derajat UKDdengan persentase pembentukan MDA dari sel bermarkah CD4+, ini menyatakanbahwa semakin berat derajat UKD semakin banyak mengalami kematian sel imun..
Ekstrak Air Biji Pepaya (Carica Papaya) dapat Menurunkan Kadar Kolesterol Total dan Kadar Serumglutamat Piruvat Transaminase (Sgpt) pada Tikus Putih Jantan Galur Wistar yang Hiperkolesterolemia Legis Ocktaviana Saputri; Bagus Komang Satriyasa; Wayan Putu Sutirta Yasa
WMJ (Warmadewa Medical Journal) Vol 2 No 1 (2017): Mei 2017
Publisher : Warmadewa University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22225/wmj.2.1.73.1-10

Abstract

Hiperkolesterolemia merupakan kelainan metabolisme lemak yang dianggap sebagai faktor yang berkontribusi dalam peningkatan risiko PJK. Biji pepaya diduga memiliki aktivitas hipolipidemik karena mengandung senyawa fitokimia yang berpengaruh pada metabolisme lemak. Penelitian ini menggunakan model eksperimental randomized pretest-posttestcontrol-group design terhadap 30 ekor tikus yang hiperkolesterolemia setelah diinduksi pakan tinggi kolesterol selama 48 hari. Tikus tersebut dibagi ke dalam 3 kelompok yaitu kelompok kontrol negatif (P0), kontrol positif (P1), dan kelompok perlakuan (P2).Aktivitas antihiperkolesterolemik dinilai melalui pengukuran kadar kolesterol total dan SGPT pretest dan posttest. Berdasarkan hasil penelitian, ekstrak air biji pepaya dosis 300 mg/kg/hari mampu menurunkan kadar kolesterol total sebesar 13,39% dan kadar SGPT sebesar 31,4% (p<0,05). Uji One Way Anova menunjukkan bahwa kadar kolesterol total dan SGPT posttest antar kelompok berbeda bermakna (p<0,05). Uji LSD menunjukkan bahwa pemberian ekstrak air biji pepaya dapat secara signifikan menurunkan kadar kolesterol total pada tikus yang hiperkolesterolemia jika dibandingkan dengan kelompok placebo. Kadar tersebut tidak berbeda signifikan dengan kelompok yang diberi simvastatin (beda rerata 0,6 mg/dL; p>0,05). Penurunan kadar SGPT diketahui berbeda bermakna jika dibandingkan kelompok placebo. Hasil tersebut dapat membuktikan bahwa pemberian ekstrak air biji pepaya dapat menurunkan kadar kolesterol total dan SGPT pada tikus putih jantan galur wistar yang hiperkolesterolemia.Kata Kunci: hipekolesterolemia, ekstrak biji papaya, kolesterol total, SGPT. [Aqueous Extract of Papaya (Carica Papaya) Seeds Decreased Total Cholesterol and Alanine Aminotransferase (Alt) Levels in Hypercholesterolemic Male Wistar Rats]Hypercolesterolemic is fat metabolism disorder which contributes to increase the risk of CHD. Papaya seeds issuspected having anti-hipercholesterolemic activity, because contains several phytochemical compounds. This study uses a model of experimental randomized pretest-posttestcontrol-group design in 30 rats that had induced hypercholesterolemia with high cholesterol diet for 48 days. Rats were divided into 3 groups: negative control (P0), positive control (P1), and the treatment group (P2). Antihypercholesterolemic activities were assessed through total cholesterol and ALT pretest and posttest levels. Results of this study has shown that aqueous extract of papaya seeds dose 300 mg/kg/day can reduce total cholesterol by 13.39% and ALT by 31.4% (p<0.05). One Way ANOVA test showed that the levels of total cholesterol and SGPT posttest are significantly different between groups (p<0.05). Further test with LSD showed that the aqueous extract of papaya seeds can significantly reduce total cholesterol when compared to P0. These results do not differ significantly from group that given simvastatin (mean difference 0.6 mg/dL; p>0.05). Decreased levels of ALT are also known significantly different when compared to P0.These result proved that aqueous extract of Carica papaya seeds can decreased total cholesterol and ALT levels in hypercholesterolemic male wistar rats.Keywords: hypercholesterolemic, papaya seeds extract, total cholesterol, ALT
IMMUNOPATOGENESIS INFEKSI VIRUS DENGUE IBN Dwipayana Manuaba; I Wayan Putu Sutirtayasa; DAP Rasmika Dewi
E-Jurnal Medika Udayana vol 2 no 10 (2013):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Dengue , adalah penyakit arboviral tersering yang tersebar di seluruh dunia. Dengue disebabkan oleh infeksi 1 dari 4 serotipe virus dengue. Virus dengue berasal dari keluarga Flaviviridae , genus Flavivirus ( virus RNA ikatan-tunggal tidak ber-segmen).Virus dengue menular ke manusia melalui gigitan nyamuk Aedes betina yang telah ter-infeksi. Virus dengue (DEN) mempunyai 4 serotipe (DEN-1 , DEN-2 , DEN-3 , DEN-4) . infeksi dari salah satu tipe virus bisa tanpa gejala di mayoritas kasus yang terjadi atau bisa menimbulkan gejala klinis. Mulai dari yang ringan dengan gejala seperti flue (yang biasa disebut demam dengue [DF] ) , bentuk yang lebih parah (yang biasa disebut demam berdarah [DHF]) , dan yang hingga menimbulkan gejala syok ( dengue syok sindrom [DSS]). Penyebab dari perkembangan dan mekanisme yang terlibat dalam patofisiologi penyakit infeksi DENV tidak bisa dengan jelas didefinisikan. Immunopatogenesis infeksi virus dengue membahas tentang jalan masuk DENV , aktivasi berlebihan imune yang menyimpang dan menginduksi autoantibody , respon humoral ,peningkatan dependen antibody
DIAGNOSE OF THYPOID FEVER WITH WIDAL TEST I Made Tomik Nurya Wardana; Sianny Herawati; I Wayan Putu Sutirta Yasa
E-Jurnal Medika Udayana vol 3 no 2 (2014):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

Thypoid fever is one of infection systemic disease cause by Salmonella enterica serotype typhi, thisbacterium is member of family Enterobacteriaciae. Everyone with thypoid fever bring thebacterium in blood stream and gastrointestinal sytem so that it can transmit the infection to othersdirectly through water or food that has been contaminated. Laboratory examination to establish adiagnosis of typhoid fever is with conventional methods, namely the culture of the bacterium andserological test Widal and non-conventional method, namely Polimerase Chain Reaction (PCR),Enzyme Immunoassay Dot (EID) and Enzyme-Linked Immunosorbent Assay (ELISA). The definitivediagnosis of typhoid fever is with isolation of Salmonella enterica serotype typhi from blood, urineor other body fluids. It is often not possible in developing countries because of inadequatebakteriologik facilities on many small hospitals, while typhoid fever is an endemic disease in thecountry. With this kind of situation, the diagnosis should be enforced by connecting thecorresponding clinical symptoms with typhoid fever and the presence of antibody titer is increasingsignificantly in the blood against antigens O or H antigens of Salmonella enterica serotype typhi(Widal test).
PREVALENSI INFEKSI DENGUE BERDASARKAN HASIL PEMERIKSAAN NS1 ANTIGEN PADA PASIEN DI NIKI DIAGNOSTIC CENTER TAHUN 2011-2012 D.P.G. Jananuraga Maharddhika; I Wayan Putu Sutirta Yasa
E-Jurnal Medika Udayana vol 4 no 12(2015):e-jurnal medika udayana
Publisher : Universitas Udayana

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Abstract

PREVALENCE OF DENGUE INFECTION BASED ON NS1 ANTIGEN EXAMINATION IN PATIENTS AT NIKI DIAGNOSTIC CENTER DURING 2011-2012Dengue is a disease caused by infection with dengue virus, which is transmitted by mosquitoes and can cause a variety of clinical manifestation, either asymptomatic or mild symptomatic to fatal. To diagnose accurately, early examination is needed. Nonstructural protein 1 (NS1) antigen is one examination that is used as a new biomarker in the early diagnosis of dengue infection. Several studies have been conducted expressing the importance of NS1 antigen as a biomarker because it can be detected before antibodies are formed.The study design was retrospective study by taking the data of patients undergoing examination dengue NS1 antigen in Niki Diagnostic Center in 2011-2012. The sample selection is done by consecutive sampling. The results obtained from the medical records are then presented descriptively with tables and narration.Patients who did a dengue checkup of NS1 antigen in Niki Diagnostic Center in 2011 amounted to 140 people with 63 men (45.0%) and 77 women (55.0%), whereas in 2012 amounted to 285 people with 166 men (58.2%) and 119 women (41.8%). For the age group with the most number of examination of dengue NS1 antigen is infant 0-5 years consists of 74 persons (52.9%) in 2011 and 161 people (58.2%) in 2012.On examination of dengue NS1 antigen in 2011, resulted in positive dengue infection as many as 18 of the 140 people (12.9%) with the largest group of dengue infection consists of 66.7% women and27.8%adulthood18-40 years. In 2012 examination dengue NS1 antigen positive results obtained dengue infection as many as 34 of 285 people (11.9%) with the largest group of dengue infection of 61.8% male and 47.1% adulthood 18-40 years.
PREVALENSI PENYAKIT GINJAL KRONIK STADIUM 5 YANG MENJALANI HEMODIALISIS DI RSUD BADUNG PERIODE TAHUN 2017-2018 I.B.GDE ANANTA MAHESVARA; WAYAN PUTU SUTIRTA YASA; AAN. NGURAH SUBAWA
E-Jurnal Medika Udayana Vol 9 No 7 (2020): Vol 9 No 07(2020): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2020.V09.i7.P06

Abstract

ABSTRAK Penyakit ginjal kronik (PGK) merupakan masalah kesehatan masyarakat global dengan prevalensi daninsidensi gagal ginjal yang meningkat, prognosis yang buruk dan biaya terapi yang tinggi. Stadium PGK dibagi menjadi 5, berdasarkan laju filtrasi glomerulus (LFG) yang masih dapat dihasilkan ginjal, dimana halini mencerminkan fungsi ginjal. Untuk pasien dengan PGK stadium 5, terapi hemodialisis (HD) merupakansalah satu pilihan utama yang sering digunakan. Tujuan dilakukannya penelitian ini adalah untukmengetahui prevalensi dan karakteristik pasien dengan PGK stadium 5 yang menjalani HD di RSUDBadung periode tahun 2017-2018. Rancangan penelitian yang digunakan pada penelitian ini adalahpenelitian deskriptif dengan pendekatan retrospektif cross-sectional study. Sampel penelitian diambil daricatatan medis populasi terjangkau secara consecutive sampling. Penelitian dilaksanakan di Instalasi RekamMedis RSUD Badung dengan sumber data yang diambil selama 1 tahun, yaitu dari Januari tahun 2018sampai dengan Desember 2018. Pada penelitian ini didapatkan prevalensi PGK stadium 5 yang menjalaniHD di RSUD Badung sebesar 0,0003%. Pasien PGK stadium 5 yang paling banyak menjalani HD adalahsebagai berikut: pasien dengan jenis kelamin laki-laki, pasien berusia 50-59 tahun, pasien yang menjalaniHD selama <12 bulan, pasien dengan diagnosis etiologis pielonefritis kronik (PNC), pasien dengan aksesvaskular arteriovenous fistula (AVF), pasien dengan kadar hemoglobin (HB) 7-10 g/dL, pasien dengankadar kalsium (Ca) <8,4 mg/dL, pasien dengan kadar fosfat (PO4) >5,5 mg/dL, pasien dengan kadar produkCa x PO4 <55 mg2/dL2, dan pasien dengan kadar asam urat <7 mg/dL.Kata Kunci: PGK, stadium 5, hemodialisis, RSUD Badung ABSTRACTChronic kidney disease (CKD) is a global public health problem with increased prevalence and incidence of kidney failure, bad prognosis and high cost of therapy. CKD is divided into 5 stages, based onthe glomerular filtration rate (GFR) that the kidneys can still produce, which reflects to kidney function.For patients with stage 5 CKD, hemodialysis (HD) therapy is one of the main choices that are often used.The purpose of this study was to determine the prevalence and characteristics of patients with stage 5 CKDwho underwent HD on Badung General Hospital in the year of 2017-2018. The research design used in thisstudy was a descriptive study with a retrospective cross-sectional study approach. The study sample wastaken from population medical records by consecutive sampling. The study was carried out in the MedicalRecord Installation of Badung General Hospital with data sources taken for 1 year, from January 2018 toDecember 2018. In this study, the prevalence of stage 5 CKD which underwent HD in Badung GeneralHospital was 0.0003%. Stage 5 CKD patients who underwent the most HD were as follows: patients with male gender, patients aged 50-59 years, patients underwent HD for <12 months, patients with etiological diagnosis of chronic pyelonephritis (PNC), patients with AVF vascular access, patients with hemoglobin (HB) levels 7-10 g/dL, patients with calcium (Ca) <8.4 mg/dL, patients with phosphate levels (PO4) >5.5 mg/dL, patients with product levels Ca x PO4<55 mg2/dL2, and patients with uric acid level <7 mg/dL. Keywords: CKD, stadium 5, hemodialysis, Badung General Hospital
HUBUNGAN ANTARA UJI ANTIGEN NON STRUCTURAL 1 (NS1) DENGAN KEJADIAN TROMBOSITOPENIA PADA KASUS DEMAM DENGUE (DD)/DEMAM BERDARAH DENGUE (DBD) DIRUMAH SAKIT ARI CANTI, GIANYAR, BALI TAHUN 2016 Ni Wayan Ari Anindita Sari; I Wayan Putu Sutirta Yasa
E-Jurnal Medika Udayana Vol 9 No 12 (2020): Vol 9 No 12(2020): E-Jurnal Medika Udayana
Publisher : Universitas Udayana

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24843/MU.2020.V09.i12.P17

Abstract

ABSTRAK Demam dengue (DD)/demam berdarah dengue (DBD) merupakan penyakit yang disebabkan virus dengue dan disebarkan melalui gigitan nyamuk Aedes aegypti. Pada DD/DBD terjadi kelainan hematologi seperti penurunan kadar trombosit di bawah normal (trombositopenia) yaitu <150.000 terkait infeksi virus dengue. Pada kondisi ini, apabila pasien tidak segera tertangani dapat jatuh ke kondisi dengue shock syndrome. Adanya suatu uji NS1 antigen sebagai rapid diagnostic test kasus DD/DBD, maka penurunan trombosit yang terjadi dapat diperkirakan dan ditangani lebih dini. Penelitian bertujuan untuk mengetahui hubungan hasil uji NS1 antigen terhadap kejadian trombositopenia pada DD/DBD. Rancangan penelitian analitik dengan pendekatan cross-sectional. Subjek dikelompokkan menjadi 2 yaitu kelompok pasien dengan hasil uji NS1 antigen positif 599 subjek dan hasil uji NS1 antigen negatif 176 subjek. Kemudian dilakukan penghitungan jumlah pasien yang sudah maupun tidak mengalami trombositopenia dari masing-masing kelompok subjek yang didapatkan dari hasil rekam medis pasien. Hasil menunjukkan jumlah pasien dengan hasil uji NS1 antigen positif dan trombositopenia sebanyak 564(94,2%) pasien, tidak trombositopenia sejumlah 35(5,8%) pasien. Pasien hasil uji NS1 antigen negatif dan trombositopenia sebanyak 78(44,3%) pasien, tidak trombositopenia 98(55,7%) pasien. Berdasarkan hasil analisis uji chi-square dengan tingkat kemaknaan 5% diperoleh p=0,001, tingkat nilai keeratan hubungan 0,554. Disimpulkan, adanya hubungan signifikan (p<0,05) antara hasil uji NS1 antigen terhadap kejadian trombositopenia pada subjek yang diteliti dengan tingkat keeratan hubungan sedang (0,40-0,599). Arah hubungan kedua variabel positif artinya apabila terdapat hasil uji NS1 antigen positif maka risiko trombositopenia semakin tinggi. Kata Kunci : demam dengue, demam berdarah dengue, trombositopenia, dengue shock syndrome, rapid diagnostic test, NS1 antigen.
Co-Authors Adhitya, Putu Gde Surya Agung Nova Mahendra Agung Wiwiek Indrayani Airin Que Ali Djamhuri Amaral, Meriana Barreto Ana Rahmawati Anak Agung Gede Sudewa Djelantik Anak Agung Ngurah Subawa Anak Agung Wiradewi Lestari Anak Agung Wiradewi Lestari, Anak Agung Anom Suardika Bagus Komang Satriyasa Bastianus Alfian Juatmadja Benny Supono Calvin Jonathan Cokorda Agung Wahyu Purnamasidhi Cokorda Istri Dewiyani Pemayun D.P.G. Jananuraga Maharddhika Desak Gde Diah Dharma Santhi Dewa Ayu Putu Rasmika Dewi Dewi, Ni Kadek Ari Kusuma Dharayani, Luh Anandita Dharma Santhi, Desak Gde Diah Dina Sophia Margina Divasta, I G Mahapraja Fatqur Rochman Feliciano Pinto, Feliciano Ferbian Milas Siswanto Gde Ary Putra Kamajaya Gede Agus Eka Tirta Putra Gede Agus Suwiryawan Gusti Ngurah Sutapa Hamsu Kadriyan Haneetha Yogarajah I A Putri Wirawati I Dewa Made Sukrama I Gde Raka Widiana I Gde Suranaya Pandit I Gede Juliarta I Gede Widhiantara I Gst Agung Dwi Mahasurya I Gusti Agung Dyah Ambarawati I Gusti Agung Ngurah Radhitya Wijaya Radhitya Wijaya I Gusti Kamasan Arijana I Gusti Made Aman I Kadek Arya Candra I Kadek Septiawan I Ketut Agus Somia I Ketut Suastika I Ketut Suwiyoga I Made Ady Wirawan I Made Bagus Cahya Wibawa I Made Bakta I Made Dwikayana I Made Jawi I Made Oka Adi Parwata I Made Sudarmaja I Made Tomik Nurya Wardana I NYOMAN MANTIK ASTAWA I Nyoman Wande I Nyoman Wande I W. Sudarsa I Wayan Gede Artawan Eka Putra I Wayan Niryana I Wayan Rosiana I Wayan Sumardika I Wayan Wita I. B. T. Wibawa Manuaba, I. B. T. Wibawa I. B. Tjakra Wibawa Manuaba I. K. Widiana, I. K. I.A.A. Widhiartini I.B.GDE ANANTA MAHESVARA IBN Dwipayana Manuaba Ida Ayu Kemala Wasita Manuaba Ida Bagus Made Suryatika Ida Bagus Ngurah Ida Bagus Putra Manuaba Ida Bagus Verry Kusumaningrat Ida Bagus Wayan Kardika Ida Kurniawati, Ida IGA Ayu Ratih Pradnyadewi Ignatius Ferdi Yuatmadja Indah Pramita Indrayani, Pande Kadek Putri Rahayu Intan Astariani Kamayoga, I Dewa Gede Alit Karta Sawenda Ketut Siki Kawiyana Ketut Suega Ketut Suryana Ketut Tuti Parwati Merati Ketut Widyani Astuti Lesmana, Cokorda Agung Bagus Jaya Luh Putu Sukma Diyanti Made Ayu Widyaningsih Made Dyah Khrisnadewi MADE RATNA SARASWATI . Manuaba, Ida Bagus Tjakra Wibawa Melania Antonia Barreto Cerqueira Michael Christian Widjaja Milaviwanda, Luh Komang Ayu N. K. Niti Susila, N. K. Naw, Sin War Ni Gusti Ayu Putu Lestari Santika Dewi Ni Kadek Mulyantari Ni Kadek Nita Utami Ni Ketut Susilawati Ni Ketut Susilawati Ni Luh Candra Mas Ayuni Ni Luh Wayan Pani Ambarasari Ni Made Dharma Laksmi Ni Made Linawati Ni Nyoman Mahartini Ni Nyoman Mahartini Ni Nyoman Mahartini Ni Putu Sriwidyani Ni Putu Widya Nandasari Ni Wayan Ari Anindita Sari Ocktaviana Saputri, Legis Pande Ayu Naya Kasih Permatananda Pande Komang Gede Bayu Wikrama Permatasari, Anak Agung Ayu Putri Poniman, S. Prabasari, Pande Visca Gayatri pradnya wibawa, komang budhi Pratiwi, Cokorda Agung Pujawan, I Made Naris Purnamawati, Susy Puspa Negara, Anak Agung Gede Angga Putu Angga Wiradana Putu Astawa Putu Budhiastra Putu Diani Wirayanti Raka-Sudewi A. A. Romdhoni, Achmad Chusnu Rudi Wisaksana S. Herawati, S. Sagung Novita Widyaningrat Santosa, I Gusti Ngurah Putra Eka Sianny Herawati Sri Maliawan Sri Wahyuni Suryawisesa, Ida Bagus Made Swari, Kadek Gyna Yadnya Thaha .. Tirtha Yasa, I Nyoman Wawan Tjokorda Gde Agung Suwardewa Tjokorda Gede Oka Tri Pramartha, I Nyoman Valari, Putu Kavita Krisnina Wayan Suardana Widiyanti, I Gusti Ayu Wijaya Kusuma Yasa, I Nyoman Wawan Tirtha Yayang Christian Yenny Kandarini