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Journal : Al-Kimia

The Influence of Ethanol Extract of Sambiloto Leaves and Sambung Nyawa Leaves To Decrease Concentration of Uric Acid Suprijono, Agus; Selta Agatha Z, Vicky; Budi Utomo, Anang
Al-Kimia Vol 11 No 1 (2023): JUNE
Publisher : Study Program of Chemistry - Alauddin State Islamic University of Makassar

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24252/al-kimia.v11i1.37280

Abstract

Hyperuricemia is a condition of high concentration of uric acid in the blood that occurs because of a buildup of uric acid in the body. Uric acid is formed as a residue of the protein metabolism of foods containing purine. Some of the active compounds in the sambiloto leave (Andrographis Paniculata (Burm.F.) Nees) and sambung nyawa leave of allegedly being able to decrease the concentration of uric acid. The aims of this research is to know the influence of the difference between the ability of ethanol extract of sambiloto leaves and ethanol extract of sambung nyawa leaves (Gynura Procumbens (Lour.)Merr.) against the concentration of uric acid in vitro as well as know the effective concentration of ethanol extract of sambiloto leaves and extract ethanol of sambung nyawa leaves against a decrease in the concentration of uric acid in vitro. The extraction method used in this research is the method of extraction re-maceration by solvent ethanol 70% in 5 days, the sampling technique used was purposive sampling. The determination of concentration of uric acid is determined out by the Spectrophotometry method ABX Pentra. Series of concentrations used was 250, 500, 750, 1000, 1250, 1500, and 1750 ppm. The results of the research, the ability is effective in decreaced the concentration of uric acid in vitro on the extract of sambiloto leaves and extract of sambung nyawa leaves is 250 ppm. Statistical results showed that there is an influence of the ethanol extracts of sambiloto leaves and ethanol extracts of sambung nyawa leaves against decreasing the concentration of uric acid in vitro. And there is no difference between ethanol extracts of sambiloto leaves with ethanol extracts of sambung nyawa leaves against a decreased in the concentration of uric acid in vitro.
Co-Authors , LINDRIASTUTI ., Sarmini A, Dhimas Adityasmara, Dhimas Ali Imron AMINUDDIN KASDI Anindita Surya Mahanani Anindya, Salsa Anis Nurhayati Annas Waladul Mufid, M. Khoirul Ariani Hesti Wulan Arif, Syahrizal Artatila, Mayangsari BAYU SEGARA PUTRA, GEDE Budi Utomo, Anang Damayanti, Tifani Aviva Defit Ekawati Dewi Saraswati Dhimas Adhityasmara Dias Alvy Pratama Djahilape, Sari R. DWI MEKARSARI, RIRIS Dyah Pratiwi, Arini DZATIYAH HUDA, MAHBUB Eka Susanti Eka Susanti Hanhadyanaputri EM, Uning Riningsih Ervina Halit Fahmi, Muhammad Qoiri Faiza, Maya Nurani GURNIWAN KAMIL PASYA, GURNIWAN KAMIL H.P., Eka Hanandi, Afwin Hanhadyanaputri, Eka Susanti Hanugalih Hanugalih, Hanugalih Harmanto Harmanto Harmanto Harmanto Harmanto Harni Pebriani, Tris Harni, Tris HENDRA SUKMANA, RAHMADHANI HENDRATNO Henri Perwira Negara, Henri Perwira Hesti W, Ariani Hesti Wulan S, A. Ariani Hesti Wulan S., A. Ariani Hesti Wulan, Hesti Hidayat, Rachmad Agus Indah Sulistyarini Indari INDARTI Indra Tejamukti Intan Martha Cahyani, Intan Martha Jacky, M Jacky, M Jon Abraham Lalang Yame Katon Galih Setyawan Ketut Prasetyo Khakim, Moh Lukman KHASANAH, ISWATIN Khasanah, Luthfiyatul Kresnawati, Yani Kurnia Imtichatus Sholichah Kusni Kusni Kusnul Khotimah Lina Roesmawati Luthfiyatin, Luthfiyatin M Jacky M Jacky M. Jacky M. JACKY M. Turhan Yani Maghsyuroh, Risdyah Khurum Mahanani, Anindita Surya MALIK HADI PRAJA, NUR Martha C, Intan Martha Cahyani, Intan Marzuqi, Muhammad Ilyas Maskur, Rini Maulana, Yudistira Rizki Maya Nurani Faiza Melisa Melisa Mohamad Sulthoni Mufid, M. Khoirul Annas Waladul Muhammad Qoiri Fahmi Muhammad Turhan Yani Muttaqien, Arif Rahman Na'imah, Zaidatun Nabilah, Shafa Rizqi Nandawati, Almania Nasution, Nasution Nia Dewi Kumalasari NINDA LAILATUL FAIDA, PUTRI Niswatin Nuansa Bayu Segara Nugroho Hari Purnomo NUR AFIFAH, IMROATUN NUR AINI, SHEERLY Nur Azizah Dwiyani Nur Habibah NUR TARSILA, HANIF Nur Zakiyatul Fakhiroh Nurasita, Putri Intan NURHAMIDIN, FAUZAN Nurhayati, Anis Pebriani, Tris Harni Prastiyono, Hendri Prastyono, Hendri Pratama, Cindy Arinda Diah PUJI RAHAYU, EGA Purwadi, Sarosa Purwantini, Dety PUTRI HIDINIA, DELLA Rachmad Agus Hidayat Raden Mohamad Herdian Bhakti Rendianto, Fakrul Aldi Rendy A.P, Dwi Bagus Rininingsih, Uning Roesmawati, Lina Roesminingsih Roesminingsih Roesminingsih, Roesminingsih Rusmi, Salsabila Rafidah Ulfah Salsa Anindya Sarmini Sarmini Sarmini Sarmini Sarmini Selta Agatha Z, Vicky SEPTINA ALRIANINGRUM Setyawan, Achmad Dicky Setyawan, Katon Galih Setyawan, Katon Galih Setyo Trisnadi Sindy Dwi Jayanti Siti Masruroh SUGENG HARIANTO Sugeng Harianto Sukma Perdana Prasetya Sulistiani, Dian Sulthoni, Mohamad Sumarno . Sunarto Sunarto Sunarto Sunarto Supriadi, Andika Susanti Hanhadyanaputri, Eka Suwarmi Suwarmi Suwarmi, Suwarmi Syahrizal Arif Syamsul Arifin Syawaldi, Rizky Bilal Tejamukti, Indra Trisa, Yosi Trisa, Yosi W, Ariani Hesti Wahyu Setiawan Waspodo Tjipto Subroto Windika, Ivenna Salsa Wisnu Wisnu wisnu wisnu, wisnu Wisnu, Mr Wiwik Sri Utami Wulan S., A. A. Hesti YOGA YULIYANTO, AFIF Yosi Trisa Yosi Trisa Yudianto, Galang Rizqullah Yuliatin yuliatin Yuliatin Yuliatin Yullia Susilaningtyas