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Effect of Piper Betle Nanospray 7% on Inflamation and IL-6 Levels in Postpartum Maternal Wounds : A Study in the Grobogan Regency Area, Central Java in 2025 Fitriyaningsih, Erna Indah; Kumorowulan, Suryati; Suwondo, Ari; Rahayu, Sri; Hiyana TD, Christin
International Journal of Social Service and Research Vol. 5 No. 6 (2025): International Journal of Social Service and Research
Publisher : Ridwan Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46799/ijssr.v5i6.1271

Abstract

Postpartum second-degree perineal lesions are common and trigger an inflammatory response with an increase in IL-6. Suboptimal treatment risks prolonging the inflammatory process and inhibiting wound healing. Piper betle Linn is recognized as an herbal ingredient with anti-inflammatory potential; its nanospray formulation is believed to penetrate deeper layers of the skin, thereby accelerating wound healing. This study evaluated the effectiveness of a 7% betel leaf extract nanospray on the healing of perineal wounds in postpartum care. The study employed a true experimental design with a pretest-posttest control group, involving 40 respondents selected through stratified random sampling. The variables examined were the use of 7% betel leaf extract nanospray and the healing of grade II perineal wounds. Data analysis was conducted using the Kruskal-Wallis test and the Mann Whitney, followed by the Wilcoxon test. The findings demonstrated that administration of Piper betle Linn 7% nanospray extract significantly accelerated perineal wound healing, as measured by the REEDA scale (p < 0.05), with the majority of the intervention group (65%) exhibiting good healing. However, there was no significant difference in IL-6 levels between the intervention and control groups (p > 0.05). Piper betle Linn 7% nanospray extract is effective in accelerating the healing of grade II perineal wounds in postpartum mothers, as indicated by a decrease in REEDA scores, but does not significantly affect the reduction of IL-6 levels.
REKOMENDASI STRATEGI PENGENDALIAN DENGUE DI KOTA BENGKULU TAHUN 2023-2025: FOCUS GROUP DISCUSSION (FGD) Triana, Dessy; Gunasari, Lala Foresta Valentine; Martini, Martini; Suwondo, Ari; Sofro, Muchlis Achsan Udji
DHARMA RAFLESIA Vol 23 No 1 (2025): JUNI (ACCREDITED SINTA 5)
Publisher : Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/dr.v23i1.39717

Abstract

Dengue is a global health problem. There has been an increase in cases of more than 15 times over the last two decades. The causes of the rise in the number of cases and the increase in infected areas are very complex and multifactorial, including viral, vector, environmental, and human factors. A comprehensive prevention strategy is needed that includes all component factors that influence dengue disease to predict the incidence of the disease. This activity aimed to implement effective dengue control in Bengkulu City to reduce the number of dengue cases. The activity partners were the Bengkulu City Health Service, Bengkulu Provincial Health Service, Community Health Centers in Bengkulu City, and surveillance officers. The method of this activity was to focus group discussion to formulate a dengue control strategy in Bengkulu City for 2023-2025.  The dengue control strategy that has been formulated can be implemented in the work area of ​​the community health center to reduce the number of dengue cases.
Pengembangan Model PACS Server Post Processing Terintegrasi “CLEMAGS” untuk Meningkatkan Keefektifan Pembelajaran Klinis pada Program Studi Imaging Diagnostik Program Pascasarjana Poltekkes Kemenkes Semarang Pranandya, Brian Ilham; Wibowo, Gatot Murti; Suwondo, Ari; Anwar, M. Choiroel; Darmini, Darmini
Jurnal Imejing Diagnostik (JImeD) Vol 11, No 2 (2025): JULY 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jimed.v11i2.13327

Abstract

Background: One aspect of digital transformation in education today is online learning or commonly referred to as E-learning. Clinical Education Management System or CLEMAGS, is an application system used for clinical education management in the field of web-based Diagnostic Imaging. The development of Clinical Learning Management System (CLEMAGS), which was built with the help of Orthanc Platform, is to create a more inventive and interactive learning model for students of Postgraduate Diagnostic Imaging study program of Poltekkes Kemenkes Semarang. Designing and developing the PACS Server Post Processing model in CLEMAGS to support activities in the Diagnostic Imaging Postgraduate Program of the Poltekkes Kemenkes Semarang and testing the effectiveness of the PACS Server Post Processing model in CLEMAGS in the Diagnostic Imaging Postgraduate Program of the Poltekkes Kemenkes Semarang.Methods: This type of research is Research and Development (RD) which uses the Rapid Application Development (RAD) research approach method. Analysis of differences in pre-test and post-test data using paired sample t-test. While analyzing the increase in effectiveness test results using the N-Gain Test.Results: The paired sample t-test results are sig. value of 0.003 (p-value 0.05), which means that there is a significant difference between the pre-test data and the post-test implementation of the PACS Server Post Processing Model in CLEMAGS. Overall, the average N-Gain score is 0.89 and is included in the “High” understanding improvement category. The percentage of N-Gain obtained was 89.94% and included in the effective category.Conclusions: The PACS Server Post Processing model in CLEMAGS is effective in improving user performance in managing medical imaging data. The TRIP-ID system is a medical image-based learning solution that can be practically applied in health education institutions. Further development can be directed toward the integration of artificial intelligence (AI) for automatic interpretation, as well as expanding implementation in various other educational institutions.
Aromatherapy Massage of Lemongrass, Kaffir Lime, and Lemon to Increase Appetite, IGF-1 (Insulin-like Growth Factor 1) Levels, Body Weight, and Height In Stunted Toddler Yuliatri, Risa; Widyawati, Melyana Nurul; Suwondo, Ari; Walin, Walin
Devotion : Journal of Research and Community Service Vol. 4 No. 10 (2023): Devotion: Journal of Research and Community Service
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/devotion.v4i10.579

Abstract

Stunting is a chronic nutritional problem caused by malnutrition over a long period of time, resulting in children becoming short. Stunting is not only a problem of impaired physical growth, but also causes children to become easily sick, impaired brain development and intelligence, so stunting is a major threat to the quality of human resources in Indonesia. Indonesia's stunting prevalence is 24.4% in 2021, based on the results of the Indonesian Nutritional Status Survey (SSGI) by the Ministry of Health. This figure is quite high and still above the standard tolerated by WHO, which is below 20%. For this reason, efforts are needed to reduce stunting rates with aromatherapy footing. The study aims to analyze the effect of aromatherapy massage on appetite, IGF-1 levels, body weight, and height in stunted toddlers. The research design used was pretest-postest with control group design. The number of samples in this study was 32 subjects, which were divided into two groups, 16 subjects in the intervention group were given aromatherapy massage 3 times a week with a duration of 15 minutes for 8 weeks and the control group was given standard care for stunting toddlers given PMT biscuits. The probability sampling technique is simple random sampling. The data studied were appetite, IGF-1 levels, body weight, and height of stunted toddlers. Data analysis using Wilcoxon Test, Man Wihtney Test, Paired T-test, and Independent T-test. The results show there were differences between before and after aromatherapy massage in the intervention group on appetite (P = 0.001), IGF-1 levels (P = 0.000), body weight (P = 0.000), and height (P = 0.000). Aromatherapy massage 3 times a week for a duration of 15 minutes for 8 weeks is effective in increasing appetite, IGF-1 levels, weight, and height of stunted toddlers.
FAKTOR YANG MEMPENGARUHI TINGKAT KESEMASAN POSTPARTUM PRIMIPARA Gurnita, Fauziah Winda; Suwondo, Ari; Astuti, Rara Sri Endang Puji
Jurnal Ilmiah Kesehatan Ar-Rum Salatiga Vol 4, No 2 (2020)
Publisher : STIKES Ar-Rum Salatiga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36409/jika.v4i2.94

Abstract

Peran sebagai ibu baru untuk pertama kali membuat perubahan besar pada peran dan kondisi psikologis primipara saat menjalani periode postpartum. Mayoritas tanda-tanda kecemasan postpartum sering diabaikan karena kurangnya kesadaran akan dampak di kemudian hari pada primipara, suami, atau hubungan dengan anggota keluarga lainnya yang akan menjadi beban psikologis bagi primipara. Metode penelitian yang digunakan adalah pra eksperimental dengan 40 sampel wanita primipara dengan kriteria persalinan normal. Faktor-faktor yang diteliti adalah usia, pendidikan, pekerjaan, status ekonomi, dan budaya etnis primipara. Hasil dari penelitian ini adalah usia, pendidikan, pekerjaan, dan status ekonomi tidak mempengaruhi tingkat kecemasan postpartum primipara. Budaya etnis mempengaruhi tingkat kecemasan postpartum primipara. Kesimpulan: Kelompok etnis membentuk lingkungan dan persepsi efektif untuk primipara dan keluarga. Karena budaya etnis membentuk lingkungan bagaimana kondisi psikologis primipara berjalan selama proses postpartum berlangsung.
Effectiveness of Transdermal Patch Compressed Red Ginger Ekstract (Zingiber Officinale Var.Rubrum) as Therapy Alternative to Flowness Breast Milk in Postpartum Mothers Ladyvia, Fiyola; Hadisaputro, Suharyo; Suwondo, Ari
Indonesian Journal of Global Health Research Vol 6 No 3 (2024): Indonesian Journal of Global Health Research
Publisher : GLOBAL HEALTH SCIENCE GROUP

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/ijghr.v6i3.3186

Abstract

Breast milk smoothness occurs because the blockage of venous and lymphatic flow increases, causing breast swelling, inhibiting milk flow, and pain in the breast and increasing body temperature, if not treated immediately there can be breast milk dams, mastitis and even breast infections. This causes pain, to reduce breast swelling non-pharmacologically can be done with the development of transdermal patch compress red ginger extract. The research purposes is a resulted in the development of a viable red ginger extract transdermal patch compress and proved its effectiveness as an alternative therapy for smooth breastfeeding in postpartum mothers. Produce and analyze its effectiveness as an alternative therapy for smooth breast milk in postpartum mothers. Method: This type of research is R&D, and quasi-experimental Pre-Posttest With Control Group Design. The sample amounted to 30 postpartum mothers divided into 2 intervention groups with the development of transdermal patches of red ginger extract and breastcare and a control group with breasrcare. The variables measured were breast milk volume, decreased swelling and breast tenderness. Consecutive sampling technique. Data collection using questionnaires and observations. Data analysis using univariate and bivariate using Wilcoxon and Mann Whitney. The development of transdermal red ginger extract patches is validated and feasible to be applied as an alternative therapy to smooth breast milk of puerperal mothers. Test results of effectiveness of increasing breast milk volume from 2,47 to 71,07 (p = 0.000), decreasing breast swelling from 3,45 to 1,32 (p = 0.000), breast pain from 2,91 to 0,14 (p = 0.001). The application of the development of Transdermal Extract Red Ginger Patch is feasible and effective as an alternative therapy against the smooth breastfeeding of puerperal mothers.
Pengembangan Model PACS Server Post Processing Terintegrasi “CLEMAGS” untuk Meningkatkan Keefektifan Pembelajaran Klinis pada Program Studi Imaging Diagnostik Program Pascasarjana Poltekkes Kemenkes Semarang Pranandya, Brian Ilham; Wibowo, Gatot Murti; Suwondo, Ari; Anwar, M. Choiroel; Darmini, Darmini
Jurnal Imejing Diagnostik (JImeD) Vol. 11 No. 2 (2025): JULY 2025
Publisher : Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jimed.v11i2.13327

Abstract

Background: One aspect of digital transformation in education today is online learning or commonly referred to as E-learning. Clinical Education Management System or CLEMAGS, is an application system used for clinical education management in the field of web-based Diagnostic Imaging. The development of Clinical Learning Management System (CLEMAGS), which was built with the help of Orthanc Platform, is to create a more inventive and interactive learning model for students of Postgraduate Diagnostic Imaging study program of Poltekkes Kemenkes Semarang. Designing and developing the PACS Server Post Processing model in CLEMAGS to support activities in the Diagnostic Imaging Postgraduate Program of the Poltekkes Kemenkes Semarang and testing the effectiveness of the PACS Server Post Processing model in CLEMAGS in the Diagnostic Imaging Postgraduate Program of the Poltekkes Kemenkes Semarang.Methods: This type of research is Research and Development (R&D) which uses the Rapid Application Development (RAD) research approach method. Analysis of differences in pre-test and post-test data using paired sample t-test. While analyzing the increase in effectiveness test results using the N-Gain Test.Results: The paired sample t-test results are sig. value of 0.003 (p-value <0.05), which means that there is a significant difference between the pre-test data and the post-test implementation of the PACS Server Post Processing Model in CLEMAGS. Overall, the average N-Gain score is 0.89 and is included in the “High” understanding improvement category. The percentage of N-Gain obtained was 89.94% and included in the effective category.Conclusions: The PACS Server Post Processing model in CLEMAGS is effective in improving user performance in managing medical imaging data. The TRIP-ID system is a medical image-based learning solution that can be practically applied in health education institutions. Further development can be directed toward the integration of artificial intelligence (AI) for automatic interpretation, as well as expanding implementation in various other educational institutions.
RABA (Rifka's Applied Behaviour Analysis) Model To Improve Tooth Brushing Skills of Autistic Children Annisa, Rifka; Djamil, Masrifan; Suwondo, Ari
Jurnal Kesehatan Gigi Vol. 11 No. 1 (2024): juni 2024
Publisher : Jurusan Kesehatan Gigi, Poltekkes Kemenkes Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31983/jkg.v11i1.10217

Abstract

Autistic children experience barriers to social interaction, communication, behavior, language, emotion and imagination. Autistic children have different characteristics from children in general. Children are not yet able to brush their teeth properly and there is no special dental health program for children with autism. The RABA (Rifka's Applied Behavior Analysis) is arranged according to their characteristics.This study aimed to develop RABA (Rifka's Applied Behavior Analysis) to improve brushing skills and decrease debris index in children with autistic children.This type of research is uses R&D method and model trial (Quasi-Experiment Pretest and Posttest with Control Group Design). The research subjects of autistic children were divided into 2 groups. The results of the model design are validated by experts. Data were tested using intraclass correlation coefficient, Chi Square, Shapiro wilk, repeated measure annova, independent sample t-test.Expert validation of RABA (Rifka's Applied Behaviour Analysis) model averaged 85.46 (very feasible) to improve brushing skills and decrease debris index of autistic children with a p-value  of 0.000. This model effectively to improve the brushing skills of autistic children with a p-value (0.033) and decrease the debris index of autistic children with p-value (0.004) compared to the control group. The application of the RABA (Rifka's Applied Behavior Analysis) model was effective to improve brushing of autistic children compared to the control group.
The Effectiveness of Kenikir Extract (Cosmos Caudatus) To Increase The Hormone Prolactin In Puerperal Mothers Hidayah, Khoirotul; Suwondo, Ari; Kusmiyati, Yuni
Eduvest - Journal of Universal Studies Vol. 3 No. 10 (2023): Journal Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v3i10.935

Abstract

Failure of exclusive breastfeeding still occurs due to insufficient milk production. Kenikir or Cosmos Caudatus has active compounds that may increase breast milk, but there has been no further research on kenikir in breast milk production. Analyzing the effectiveness of kenikir extract in increasing prolactin hormone levels in puerperal mothers. This type of research is a true experiment with pretest posttest control group design. The independent variable is nikir extract. The dependent variable is the hormone prolactin. The sample of 40 postpartum mothers was divided into 20 mothers in the control group and 20 mothers in the intervention group. The analysis used the Paired T Test and Wilcoxon to determine the differences before and after the intervention in each group. Then Mann Whitney's analysis was carried out on differences between groups. Administration of 300 mg of kenikir extract for 14 days can increase the hormone prolactin with an average of 44.70 ng / ml p value 0.0001. Giving kenikir extract is effective in increasing the hormone prolactin in postpartum mothers.
IDENTIFIKASI SENYAWA GARLISIN DAN KUERSETIN SEBAGAI SENYAWA ANTIMIKROBA PADA SEDIAAN BASAH DAN KERING BAWANG PUTIH (Allium sativum L.) Yunus, Fanny Thresia; Suwondo, Ari; Martini, Martini
Care : Jurnal Ilmiah Ilmu Kesehatan Vol 8, No 2 (2020): EDITION JULY 2020
Publisher : Universitas Tribhuwana Tunggadewi

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (632.09 KB) | DOI: 10.33366/jc.v8i2.1693

Abstract

Indonesian people have long used garlic as traditional medicine because it contains various chemical compounds that are beneficial to the body. In this study identification of garlicin and kuersetin compounds in garlic as an antibacterial. This study requires 500 grams of garlic each in wet preparations consist of fine garlic and garlic extract, and dry preparation consists of garlic powder. In addition, this research requires 2,1 liters of 96% ethanol. Garlic is dried at 400C with TMI Vacuum Oven and extracted at 250C. Garlic powder is made using Krisbow dry cabinet with a temperature of 1000F and a pressure of 10 Pa. Garlisin content was identified by GCMS Shimadzu TQ8030 and FTIR Perkin Elmer Spectrum Two UATR, while identification of quercetin using Shimadzu HPLC type UFLC. The result shows that the compound garlicin (C6H10S2) was found in the three samples with identical similarity levels. In addition, the three samples showed differences in kuersetin content. The highest kuersetin content was 458.729 ppm garlic extract while the lowest kuersetin content was 81.181 ppm fresh garlic. Both of these compounds have potential as antimicrobial compounds.
Co-Authors Achmad Zulfa Juniarto Ahmaniyah, Ahmaniyah Anak Agung Gede Sugianthara Annisa, Rifka Apriyana Irjayanti Arwani Arwani Arwani Asmawati, Lilik Astuti, Rara Sri Endang Puji Baju Widjasena Bedjo Santoso Kadri Beniqna Maharani Besmaya Bina Kurniawan Budhi R, Kamilah Daniati, Nia Daniati Darmini Darmini Daru Lestantyo Dengo, Moh. Rivandi Dessy Triana Desyandri Desyandri Deviana, Meli Dhanio, Yeyen Wulandari Diyah Fatmasari Djamil, Masrifan Dwi Cahyanti, Dwi edy susanto Ekawati Ekawati Endah Kumala Dewi Erlina Krisanti Fachry Abda El Rahman Faridah, Salsabila Nur Ferry Ardhiansyah Fitriyaningsih, Erna Indah Freya Nazera Iskandar Gatot Murti Wibowo, Gatot Murti Gunasari, Lala Foresta Valentine Gurnita, Fauziah Winda Hadisaputro, Haryo Hamdan, Yusuf Lensa Hanif, Fastabiqul Haryono, Nathasia Elga Heri Nugroho Hidajati, Kamilah Hidayah, Khoirotul Hiyana TD, Christin Husna, Dewi Asmaul Krisdiana Wijayanti Kurnianingsih Kurnianingsih, Kurnianingsih Ladyvia, Fiyola Laksana, Ni'matun Faizah M. Choiroel Anwar Martini Martini Mateus Sakundarno Adi, Mateus Sakundarno Melyana Nurul Widyawati Muchlis Achsan Udji Sofro Mulya, Dimas Yuzril Nainggolan, Wiwiek Neni Susilaningsih Noor Pramono Nurharisah, Siti Nurjazuli Nurjazuli Pradesi, Regina Pranandya, Brian Ilham Pujiastuti, Rr. Sri Endang Putri, Rifa Fauziah Syaifia Rasipin Rasipin Runjati Sarwendah Dewi Astuti, Sarwendah Dewi Siswi Jayanti Siti Rizki Amalia Sofro, Muchlis AU Sofyanita, Eko Naning Sri Anureksi SRI RAHAYU Sudirman Sudirman Sudiyono Sudiyono Suharyo Hadisaputro Supriyana Supriyana, Supriyana Suroto Suroto Suryati Kumorowulan Syuhada, Ambar Dani Theresia Ristadeli Tinuk Istiarti Tri Utami, Annisa Rachmah Tri Wiyatini, Tri Ulfa Nurullita Wahyuningtyas, Miranda Gita Wahyuningtyas Walin Walin, Walin Waode Fitrah Sari Yuliani Setyaningsih Yuliatri, Risa Yulisnawati Yulisnawati Yulistina Yulistina Yuni Kusmiyati Yuniarti - Yunus, Fanny Thresia