Article Per Year (5 Year)
p-Index From 2020 - 2025
5.276
P-Index
This Author published in this journals
All Journal Jurnal Ilmu Kedokteran (Journal of Medical Science) Jurnal Kesehatan Andalas Berkala Ilmu Kesehatan Kulit dan Kelamin JURNAL PENGABDIAN KEPADA MASYARAKAT The Indonesian Biomedical Journal Collaborative Medical Journal (CMJ) Buletin Ilmiah Nagari Membangun Majalah Kedokteran Andalas Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Health and Medical Journal Andalas obstetrics and gynecology journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Scientific Journal Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Jurnal Kesehatan Masyarakat Indonesia (JKMI) Jurnal Riset Ilmiah Seroja Husada: Jurnal Kesehatan Masyarakat
Tofrizal
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

Published : 48 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : Andalas obstetrics and gynecology journal

 1 
Differences of Fibronectin Levels in First Trimester Normal Pregnency and Miscarriage Fadhilah, Maisarah; Utama, Bobby Indra; Tofrizal, Tofrizal
Andalas Obstetrics And Gynecology Journal Vol. 8 No. 1 (2024)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/aoj.8.1.648-653.2024

Abstract

Introduction: Miscarriage is a reflection of the low quality of health in pregnant women. The incidence of miscarriage in the world accounts for 23 million (15%) of the 130 million births per year and up to 80% of miscarriages occur in the first trimester of pregnancy. Miscarriage will affect a woman's social, physical, and psychological. The complexity of the negative impact of miscarriage makes it necessary to pay special attention. Biomarker examination is needed to more accurately identify pregnancies at risk of miscarriage before the appearance of clinical symptoms. The use of fetal fibronectin (fFN) levels have been used as a marker of unexpected labor and as evidence of premature rupture of the fetal membranes. Normally fFN can be detected in cervical and vaginal secretions at <20 weeks gestation. The presence of fFN at >22 weeks gestation indicates disruption of the uteroplacental surface. Therefore, if screening for fibronectin levels using the Enzyme-Linked Immunosorbent Assay (ELISA) test can be carried out in the first trimester of pregnancy, there is a high possibility that miscarriage can be prevented.Method: The type of research is analytical observational research with a cross-sectional research design. The stored samples were examined for fibronectin levels using the ELISA test, which included 21 blood serum samples from normal pregnancy patients in the first trimester and 21 miscarriage samples.Results: The results of the ELISA test produced an average first-trimester normal pregnancy fibronectin level of 118.8 ± 18.4 ng/mL while the miscarriage fibronectin level was 208.2 ± 152.0 ng/mL. Data analysis using the Mann-Whitney test obtained a p-value = 0.138, which means there was no significant difference in fibronectin levels between normal pregnancy in the first trimester and miscarriage.Conclusion: This study concludes that fibronectin levels are not specific biomarkers in detecting miscarriage in the first trimester of pregnancy.
Co-Authors Abdiana Abdiana, Abdiana Afdal Afdal Afriani Afriani, Nita Aini, Julpa Nurul Aizah, Havina Nurul Aljassri, Resti Karunia Alvarino Alvarino Amel Yanis Aqilah, Giffary Zahida Ariani, Novita Ariani, Yuliza Arnofyan, Budi Pratama Asri, Ennesta Aswiyanti Asri Aswiyanti Asri Athika Rahmawati Avit Suchitra Azmal, Nita Afriani Cimi Ilmiawati, Cimi Daan Khambri Deddy Saputra Deddy Satriya Putra Desmawati Desmawati Dessy Arisanty Devianti, Loli Djong Hon Tjong Dwi Yanti Fioni Putri Dwisari Dillasamola Elli Firdamila Elmatris Elmatris Elmatris, Elmatris Endrinaldi Ennesta Asri Erkadius Erkadius Eryati Darwin Eryati Darwin Eti Yerizel Fadhilah, Maisarah Fadil Oenzil Fadillah Fadillah Fajriza Yona Fesdia Sari Firdamila, Elli Gardenia Akhyar Gusti Revilla Hafni Bachtiar Handriyani, Fitri Nur Hasmiwati henny Mulyani Henny Mulyani Hera Novianti Hirowati Ali, Hirowati Husna Yetti Husna Yetti Intan, Shinta Ayu Khotimah, Rifqoh Kusumardani, Dini Lubis M Mahata, Liganda Endo Maliza, Rita Mayorita, Pamelia Miftah Irramah Muhammad Idris Muhammad Nazri Janra Mustika Sari Naqia, Masyithah Nelzima, Maisyah Nita Afriani Nofrita Nofrita Novianti, Hera Novita Ariani Noza Hilbertina Noza Hilbertina, Noza Nur Afrinin Syah Nuzulia Irawati O ktora, Meta Zulyati Oktora, Meta Zulyati Putra Santoso Putri Amran, Fajriana Anggun Putri, Biomechy Oktomalio Putri, Nabila Priscilla R. Zuryati Nizar Rahmi Ramadhani Rauza Sukma Rita Restu Susanti Ria Oktavia Ria Oktavia Rina Gustia Rio Hendra Robby Jannatan Rony Rustam Runky Pebranka Rusnita, Dewi RZ Nizar Safnita, Dewi Salmiah Agus Salmiah Agus Salmiah Agus Selfi Renita Rusjdi, Selfi Selly Alinta Syukri Setiawatu, Yessy Sisca Dwi Yarni Siti Nurhajjah Sri Lestari SRI LESTARI Sri Wahyuni Handayani Sri Wahyuni Handayani, Sri Wahyuni Suci Rahmadhani Sukri Rahman Syamel Muhammad Tiffany, Begum Utama, Bobby Indra Yarni, Sisca Dwi Yenita . Yenita Yenita Yenny Raflis Yessy Setiawati Yessy Setiawati Zehan Afifa Yusran Zulfadli Syahrul, Muhammad