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siti rahmah
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Journal : NERS Jurnal Keperawatan

 1 
Determinants of Medication Adherence in Advanced Pulmonary Tuberculosis: A Systematic Review Siti Rahmah; Anisah Ardiana; Iis Rahmawati
NERS Jurnal Keperawatan Vol. 21 No. 1 (2025): NJK Volume 21, No 1
Publisher : Fakultas Keperawatan Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/njk.v21i1.243

Abstract

Adherence to therapy is an essential component of successful pulmonary tuberculosis treatment, affecting patient recovery, prevention of drug resistance, and public health outcomes. Understanding compliance factors can guide interventions to improve treatment success rates. This systematic review explored the factors influencing adherence to therapy among tuberculosis patients, synthesizing evidence from various studies to understand the problem comprehensively. A systematic literature search followed PRISMA guidelines, including primary databases and screening for relevant studies. Twenty-four studies that met the inclusion criteria were analyzed. Data extraction and quality assessment were carried out to ensure the robustness of the findings. There were 2,729 articles identified according to the criteria, and 24 articles were obtained that analyzed several factors affecting patient with tuberculosis (PTB) therapy adherence, which were classified into individual, socioeconomic, and healthcare system domains. Key individual factors include patient knowledge about TB, stigma, mental health challenges, and substance use. Socioeconomic barriers, such as financial constraints and limited social support, are particularly prominent. Health system factors, including accessibility, quality of provider-patient communication, and ease of care facilities, also significantly affect compliance. Addressing adherence to TB therapy requires a multi-faceted approach that combines patient education, socioeconomic support, and healthcare system improvement. Targeted interventions based on these findings are critical to improving treatment outcomes and reducing TB-related health disparities
Co-Authors A Halim Adella Adella Afia Salsabila Agus Junaidi Agus Setyono Ahmad Yamani Alaisya Amana Fazira Andreas Hari Kristiyanto Angga Prasetia Anisah Ardiana Anna Malia Ardi Paminto Aria Nanda Arifa Nurriqli Arnita Rahmawaty Aziza Arzetia Firlyani Astini, Dewi Aulia Azizah Balqis , Putri Bashori Birul Daini CICIK SURIANI Darmiwati Darmiwati Darmiwati Darmiyati Dede Ardiansah Dede Kurniawati dessy dwitalia sari Devan Zulfangga Dewi Maritalia Diah Yudhawati Dicky Hariansyah Dina Hermina Dinda Kartika Aulia Putri Eltrik Setiyawan Eni Susanti Erly Sulistiyawati Ernawulan Syaodih Eva Naulia Feni Puspitasari Fitri Wahyuni Habriyanto Habriyanto Hafni Indriati Nasution Hamdan Khairul Mubarak Harfindo Nismal Haris Faulidi Asnawi Harun Ar-Rasyid Hendra Taufik Herda Ariyani Herdiansyah Herlita, Jumi Hidayattullah, Mhd Hilmi Mizani Indah Wahyuni Indasah Inka Sisilia Putri Irnawati Marsaulina Irsan Tricahyadinata Jonyanis " Juliana Kadir, M. Yakub Aiyub Kasypul Anwar Khairunnisa Lahmudinur Liananiar Liananiar M. Haris Fadillah M. Ramli M. Ramli, M. Ramli M. Rio Khaitsam Pratama M. Sunandi Mahmudah, Istiyati Mahyarni Mahyarni Malena Masbur Masbur Maymunah Maymunah Megawati, Cut Merisa Nazlia Merry Alicia Miftah Al Royyen Pratama Moondra Zubir Muhammad Al Mansur Muhammad Rasyid Shiddiq Muhammad Yuliansyah Mustaqiim Pangestu Ngadimin Ngadimin Noor Malihah Norhasanah Norlaila Norlaila Nur Indrawati Lipoeto Nur Zakiah Harahap Nuraina Nuraina Nurmaini Dalimunthe Nurmala Nurmala Nurmala Nurmala Nurul Izzah Al Kamaliah Nurul Qomaria Otang Kurniaman Purwoko, Agus Puspita Nurul Sabrina Putri Andjani Nur Afifah Putriana, Marissa Rahmawati, Iis Ratna Pangastuti Rindang Farihah Rini Selly Rohmatun Naja Rury Febrina Rusi Rusmiati Aliyyah Saftia Aryzki Salamah Shofa Wardiyanti Siti Maharani Chairunnisa soewarno warno Sri Fitriani Sri Hidayanti Subhanjaya Angga Atmaja Sulfi, Aina Sultoni Harahap Sunarno Basuki SYAIFUL BAHRI Taufik Ashar Trisnawati Hutagalung Triyana Syahfitri Umar Fauzan Wahyu Aprilliyandi Warul Walidin Ak Wina Witanti Woro Susanti Yara Yulia Yatimatul Huryanah Yulia Ernida Yusnimar Sahan Yuswita Yuswita Zahri Darni Zainuddin Muchtar Zariul Antosa Zuhri D Zulkarnain Zulkarnain