Article Per Year (5 Year)
p-Index From 2021 - 2026
4.322
P-Index
This Author published in this journals
All Journal Jurnal Sains Materi Indonesia Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Tapis : Jurnal Teropong Aspirasi Politik Islam Prosiding Semnastek al-Afkar, Journal For Islamic Studies Fair Value: Jurnal Ilmiah Akuntansi dan Keuangan Majalah Patologi Indonesia Bioscientia Medicina : Journal of Biomedicine and Translational Research Jurnal Manajemen Informasi Kesehatan Indonesia (JMIKI) Attractive : Innovative Education Journal JIEB : Jurnal Ilmiah Ekonomi Bisnis Jurnal Fakultas Ilmu Keislaman UNISA Kuningan Jurnal RSMH Palembang Kaunia: Integration and Interconnection of Islam and Science Journal International Journal of Educational Research Excellence (IJERE) Jurnal Manajemen dan Bisnis Jurnal Ekonomi Bisnis, Manajemen dan Akuntansi (JEBMAK) Jurnal Riset Rumpun Ilmu Ekonomi (JURRIE) Metalurgi RESLAJ: Religion Education Social Laa Roiba Journal Jurnal Dirosah Islamiyah El-Mujtama: Jurnal Pengabdian Masyarakat EduInovasi: Journal of Basic Educational Studies Mimbar Kampus: Jurnal Pendidikan dan Agama Islam Jurnal Riset Multidisiplin Edukasi Journal of Financial Management & Accounting
Ika Kartika
Unknown Affiliation
Religion Arts Humanities Biochemistry, Genetics & Molecular Biology Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

Published : 44 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 44 Documents
Search

 1   2   3   4   5 
Hubungan antara Ekspresi VEGF dan Karakteristik Kliniko-patologis pada Karsinoma Sel Skuamosa Serviks Linda Fatrisia; Jusuf Fantoni; Ika Kartika; Erial Bahar
Majalah Patologi Indonesia Vol. 22 No. 3, September 2013
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

ABSTRAK Latar belakang Kanker serviks masih menjadi masalah yang signifikan di seluruh dunia. Angiogenesis sangat berperan dalam hal progresivitas, invasi dan metastasis.Vascular endothelial growth factor (VEGF) sebagai faktor angiogenik primer merupakan salah satu faktor prognostik karsinoma sel skuamosa serviks bila ekspresinya meningkat. Penelitian ini bertujuan untuk mengetahui hubungan antara ekspresi VEGF dan karakteristik klinikopatologis pada karsinoma sel skuamosa serviks. Metode Penelitian ini adalah penelitian cross sectional. Lima puluh tiga sampel terdiri atas 40 jaringan hasil biopsi dan 13 histerektomi diambil dari arsip di bagian Patologi Anatomi RSMH, dilakukan pulasan dengan antibodi VEGF, diidentifikasi dan dianalisis hubungannya dengan stadium klinis, derajat keganasan histologi, invasi limfovaskular, status limfonodus, kedalaman invasi dan keterlibatan parametrium. Hasil Ekspresi VEGF positif pada karsinoma sel skuamosa serviks lebih banyak dijumpai pada kelompok usia >50 tahun, stadium IIIB dan IVA, derajat keganasan semakin buruk, invasi limfovaskular dan status limfonodus positif serta kedalaman invasi stroma hingga 2/3 bagian luar dan tanpa keterlibatan parametrium. Terdapat hubungan yang bermakna antara ekspresi VEGF dengan kategori usia (p=0,038) dan korelasi yang kuat antara persentase positif ekspresi VEGF dengan usia (r=0,709) dan derajat keganasan (r=0,897). Namun, tidak ada hubungan yang bermakna antara ekspresi VEGF dengan karakteristik klinikopatologis (p>0,05). Kesimpulan VEGF belum dapat digunakan sebagai faktor prediktor progresivitas pada karsinoma sel skuamosa serviks Kata kunci : Karsinoma sel skuamosa serviks, VEGF, karakteristik klinikopatologis. ABSTRACT Background Cervical cancer remains a significant problem worldwide. The angiogenesis has an important role in the progression, invasion and metastasis. VEGF is a primary angiogenic factor that is one of the prognostic factor of cervical squamous cell carcinoma if the expression of VEGF increases. This study aimed to determine the relationship between the expression of VEGF and clinicopatological characteristics of the cervical squamous cell carcinoma. Methods It was a cross-sectional study. Fifty-three samples of biopsy and hysterectomy tissue were from the archives of the Anatomical Pathology Department of RSMH, stained with VEGF antibody, identified and analyzed the relation to clinical stage, histological grade, lymphovascular invasion, lymph node status, depth of invasion and parametrial involvement. Results The positive expression of VEGF in cervical squamous cell carcinoma was more common in the age group > 50 years, stage IIIB and IVA, the worse histological grade, the positive invasion lymphovascular and lymph nodes status, deep of stromal invasion up to the outside 2/3 and without parametrial involvement. There was a significant correlation between the expression of VEGF and the age category (p=0.038) and a strong correlation between the percentage of positive expression of VEGF andthe age range (r=0.709) and the histological grade (r=0.897). There was no significant correlation between the expression of VEGF and clinicopatologic characteristics (p>0.05). Conclusion VEGF can not be used as a progression predictor factorof thesquamous cell carcinoma. Key words : cervical squamous cell carcinoma, VEGF, clinicopathologic characteristics
Ekspresi E-cadherin dan p63 pada Karsinoma Sel Skuamosa Kulit dan Pseudoepitheliomatous Hyperplasia Amelia Amelia; ika Kartika; Zulkarnain Musa
Majalah Patologi Indonesia Vol 27 No. 2, Mei 2018
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Latar belakangPada spesimen biopsi yang berukuran kecil, terkadang patolog mengalami kesulitan untuk membedakan karsinoma sel skuamosa kulit dan pseudoepitheliomatous hyperplasia. Penurunan ekspresi E-cadherin dan overekspresi p63 dapat dijumpai pada neoplasia ganas, dan sebaliknya pada lesi non neoplastik. Tujuan penelitian ini untuk menganalisis perbedaan ekspresi E-cadherin dan p63 pada karsinoma sel skuamosa kulit dan pseudoepitheliomatous hyperplasia.MetodePenelitian ini merupakan penelitian observasional analitik dengan rancangan potong lintang. Spesimen karsinoma sel skuamosa kulit yang diteliti sebanyak 23 kasus (13 kasus dengan derajat diferensiasi baik, 6 kasus dengan derajat diferensiasi sedang, 4 kasus dengan derajat diferensiasi buruk) dan 15 kasus pseudoepitheliomatous hyperplasia, kemudian dilakukan pewarnaan imunohistokimia E-cadherin dan p63 dan dinilai ekspresinya.HasilPada karsinoma sel skuamosa kulit tampak penurunan ekspresi E-cadherin (p=0,000) dan overekspresi p63 (p=0,000) jika dibandingkan dengan pseudoepitheliomatous hyperplasia.KesimpulanPenelitian ini menunjukkan perbedaan ekspresi E-cadherin dan p63 antara kasus karsinoma sel skuamosa kulit kulit dengan pseudoepitheliomatous hyperplasia. Sehingga E-cadherin dan p63 merupakan dua marker penting yang cukup andal untuk membedakan kasus karsinoma sel skuamosa kulit khususnya membedakan karsinoma sel skuamosa kulit berdiferensiasi baik dengan pseudoepitheliomatous hyperplasia.
Analisis Ekspresi Interleukin-17 pada Karakteristik Klinikopatologi Karsinoma Payudara Nyiayu Fauziah Kurniawati; Ika Kartika; Citra Dewi; Theodorus
Majalah Patologi Indonesia Vol. 30 No. 1, Januari 2021
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v30i1.461

Abstract

BackgroundInteraction between cancer cells and tumor microenvironment plays roles in cancer proliferation and invasiveness. Many type ofcytokine produced by inflammatory cells in tumor stroma could stimulate tumor proliferation and invasiveness, such as interleukin-17.The aim of this study is to determine the correlation between IL-17 expression and clinicopathological characteristics of breast cancer.MethodsSerial cases study was performed by enrolling 40 paraffin block of breast cancer patients. Clinicopathological characteirstics werenoted, including age, histopathological subtype and grade, TILs, lymphovascular invasion and molecular subtype. TILs were scoredby denomination area of stromal tissue occupied by mononuclear cells over total stromal area. Expression of IL-17 was examined byusing immunohistochemistry with anti-IL-17 antibody and counted from stromal mononuclear cells cytoplasm staining from five areas.The average value was used as a cut-off point in determining level of expression. Data were analysed by using SPSS v.22.ResultsMajority of the patients were more than 40 years old (75%), histopathological grade III (77.5%), without lymphovascular invasion(62.5%), luminal B molecular subtype (57.5%), and non-dominant TILs (95%). IL-17 expression was not significantly correlated withclinicopathological characteristics with p value=0.079, 0.600, 0.739, 0.883 and 1.000 respectively for age, histological grade,lymphovascular invasion, molecular subtype and TILs.ConclusionInterleukin-17 expression and clinicopathological on characteristics of breast carcinoma between histopathological grade, TILs, andlymphovascular invasion showed no significant differences. There was a tendency that the higher IL-17 expression, the higherhistopathological grade, the lower TILs and positive lymphovascular invasion
Kepadatan CD8 di Lingkungan Mikrotumor pada Subtipe Diffuse Large B Cell Lymphoma Indah Yunalda; Krisna Murt; Aida Farida; Ika Kartika; Erial Bahar
Majalah Patologi Indonesia Vol. 30 No. 2, Mei 2021
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v30i2.466

Abstract

BackgroundDiffuse Large B Cell Lymphomas (DLBCL) is divided into two subtypes, GCB and non-GCB, which are determined based on Hans'salgorithm. The GCB subtype has a better prognosis than non-GCB. Some studies indicate that the tumor progression wasinfluenced by tumor microenvironment, including CD8+ TILs located both surrounding tumor cells and peripheral. This study aims todetermine the density of CD8+ TILs in the tumor microenvironment of DLBCL subtypes.MethodsA Cross sectional study of 40 samples of DLBCL registered to Department of Anatomical Pathology Faculty of Medicine UniversitasSriwijaya/Dr. Mohammad Hoesin Palembang Hospital from 1st October 2017 to 31st December 2018. All samples were stained usinganti-CD8 antibody, afterward, lymphocytes express CD8 were assessed both in surrounding tumor cells and peripheral. The densityof CD8 in each DLBCL subtype was analyzed statistically using Mann Whitney U Test.ResultsIn this study, non-GCB subtype was found higher in comparison to GCB subtype (72.5%) and the samples was dominated by youngages (75%). Significantly, peripheral CD8 density was higher than that of surrounding tumor cells, both in the GCB (p=0.003) andnon-GCB subtypes (p=0.000).ConclusionIn both subtypes, CD8 density is higher in peripheral than surrounding tumor cells and a high density in surrounding tumor cells willbe followed by an increase in peripheral CD8 density.
Co-Authors A. Tamagola, Rendi Hadian Aa Nugraha Abdul Munip Agustin Suci Rizkianti Ahmad Hendrawan Ahmadi Usman Aida Farida Ali Alhamidi ALIMUDIN Alwi Dahlan Amelia Amelia Amie Primarni Anandha Budiantoro Aprilia Erryani Ari Sukawan Aspitriani Azwar Abdurakhman Bambang Soegijono Bambang Sriyono Bela Oktavia Cahya Sutowo Chaerunnisa Chaira Saidah Citra Dewi Dede Atung Dede Oop Isofah Devi Eqtriana Setyaningsih Dhyah Annur Dicky Fauzi Firdaus Ellys Ellys Endang Sutisna Eri Setiawan Erial Bahar Ernawati Esa Hari Wibowo Fachru Abdul Rahman Fadil Pramudhya Hoesain Farij Makarim Fariz Fudla Fasih Fendy Rokhmanto Fendy Rokhmanto Franciska Pramudji Lestari Franciska Pramuji Lestari Heriman, Muhammad I Nyoman Gede Putrayasa Astawa Ian Effendi Ibrahim Purawiardi Iffiani, Zelly Iim Suryahim Ika Kartika Indah Yunalda Jayawarsa, A.A. Ketut Jessica Natalia Juliana Jusuf Fantoni Karnawati, Yosevin - Kgs. M. Yusuf Arief Akbar Khiarul Umam Koko A. Mutolib Krisna Murt Krisna Murti Krisna Murti Linda Fatrisia Lyandra S Sitorus M Ikhlasul Amal M. Irfan Mahdalena Juniarsih Makmudi Mediarty Syahrir Mohamad Taufik Azis Muh. Safar, Muh. Muhammad Hafidz Baihaqi Muhammad Hafiz Mulia, Deddy Primadona Mutiara Srikandi Ngabidin Nia Nurhayati Ningsih, Nining Surya Noor Albar Nora Ramkita Novadian Suhaimi Nurazizah Nurdin Rohendi, Muh Nyiayu Fauziah Kurniawati Opan Arifudin Putri Sekar Sari Rahma Amelia Raihan Nuryasa Fartusi Reza Rizkia Kamal Ria Yuni Rahmawati, Mayta Novaliza Isda, Siti Fatonah, Riyanto Rosdianto RR. Ella Evrita Hestiandari Rudi Iskandar S. Nurul Amanah Ratna Sari Saepudin Sahar Layali SITI AMINAH SITI KHODIJAH Siti Ropiah Sitti Hasnah Sulistyoso Gian Sukarso Suly Auline Rusminan Suprapti Slamet Surono Surono Surudin, Yan Syaeful Anwar Syahpri Putra Wangsa Theodorus Tubagus Ahmad Vanessa Vicario Vita Jamilah Wahidin Wiwi Uswatiyah WULANDARI Yudi Nugraha T Yusi Srihartini Yuwono Yuwono Zulkarnain Musa Zulkhair Ali