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All Journal Jurnal Kedokteran Syiah Kuala Berkala Ilmu Kesehatan Kulit dan Kelamin Folia Medica Indonesiana Indonesian Journal of Tropical and Infectious Disease Majalah Obstetri dan Ginekologi Qanun Medika - Medical Journal Faculty of Medicine Muhammadiyah Surabaya J-Dinamika: Jurnal Pengabdian Kepada Masyarakat YARSI Medical Journal Jurnal Respirasi (JR) JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Jurnal Abdi Insani Majalah Biomorfologi (Biomorphology Journal) Jurnal Layanan Masyarakat (Journal of Public Service) Indian Journal of Forensic Medicine & Toxicology Archives of Pediatric Gastroenterology, Hepatology, and Nutrition Journal of Clinical Microbiology and Infectious Diseases Jurnal Widya Medika Kesmas: Jurnal Kesehatan Masyarakat Nasional (National Public Health Journal)
Eko Budi Koendhori, Eko Budi
Departemen Mikrobiologi Fakultas Kedokteran Universitas Airlangga
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Prevalence And Pattern Sensitivity Multidrug Antibiotics Resistant Pseudomonas aeruginosa in the High Care Unit at Dr. Soetomo General Academic Hospital Period 2022-2023 Kusumawati, Ratna; Koendhori, Eko Budi; Mertaniasih, Ni Made; Ikhwani, Irfan Arif; Hidayat, Dimas Firman; Levani, Yelvi; Paramitha, Ayu Lidya
Qanun Medika - Jurnal Kedokteran FK UMSurabaya Vol 8 No 02 (2024): Qanun Medika Vol 08 No 02 2024
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/jqm.v8i02.22152

Abstract

The prevalence of Multidrug antibiotic-resistant Pseudomonas aeruginosa (MDRPA) has been increasing during the decade And has become attention in hospital patients. This retrospective descriptive descriptive aimed to determine the prevalence of MDRPA and its sensitivity patterns. Data were taken from results of bacterial culture and antibiotic resistance tests from various clinical specimens from patients at Dr. Soetomo General Academic Hospital throughout 2022-2023. The resistance test was carried out using a Vitek 2 compact instrument. MDRPA is defined as Pseudomonas aeruginosa that is not sensitive to three or more of the following classes of antibiotics: meropenem or imipenem, ciprofloxacin, gentamicin or amikacin, ceftazidime or cefepime, and piperacillin/ tazobactam. The prevalence of MDRPA was 57.0%. MDRPA isolates were also the most common origin from the burn unit and HCU A (high care unit A), mostly from pus specimens and sputum. Pseudomonas aeruginosa sensitivity was best with piperacillin/tazobactam (55.5%), meropenem (54.8%), amikacin (47.5%), gentamicin (46.5%), cefepime (46.3%), ceftazidime (45.0%), ciprofloxacin (44.7%) and aztreonam (43.2%). The sensitivity of MDRPA to antibiotics is much lower than that of Pseudomonas aeruginosa. This study showed high number of MDRPA specifically in Surabaya and the pattern sensitivity of Pseudomonas aeruginosa can become guidelines in choosing antibiotics treatment for patients.
Co-Authors ACHMAD RIFAI Alimsardjono, Lindawati Alpha Fardah Athiyyah Anak Agung Putri Nadia Paramitha Andy Darma Andy Setiawan Ayu Lidya Paramitha Bagus Meurah Suropati Bambang Purwanto Betty Agustina Tambunan Catur Endra Arky, Catur Endra Cynthia Dwi Ramadhanie Deby Kusumaningrum Dewi Ratna Sari Dewinta Enggar Pramesthi Dian Neni Naelasari Diani Dwi Indrasari Dimas Firman Hidayat Eddy Bagus Wasito Endraswari, Pepy Evy Ervianti Fernanda Toriq Ainur Rochman Fikri Sasongko Widyatama Gatut Hardianto, Gatut Hanik Urifah, Hanik Harsono, Setio Henky Mohammad Masteryanto Hermanto Tri Joewono Hidayat, Dimas Firman I Gusti Made Reza Gunadi Ranuh Ikhwani, Irfan Arif Imam Susilo Irfan Arif Ikhwani Ismi Masyithah Jayanti Putri, Jayanti Juita, Liza Puspa Senja Asmara Juniastuti Juniastuti Kadariswantiningsih, Ika Kawilarang, Arthur Pohan Khadijah Rizky Sumitro Kuntaman Kuntaman Kusumaningrumm, Deby Lestari, Aprilia Dwi Linda Dewanti Lindarto, Wira Widjaya M. Amin M. Amin ManikRetno Wahyunitisari Mia Rahardjo Muhammad Aafi Baharuddin Attamimi Muna, Nafdzu Mahmudatul Muna, Nafdzu Makhmudatul Nasicha, Arifatun Ni Made Mertaniasib Ni Made Mertaniasih Ni Njoman Juliasih Nurul Wiqoyah, Nurul Nuswantoro, Djohar Paramitha, Ayu Lidya Pepy Dwi Endraswari, Pepy Dwi Priyo Budi Purwono Putri, Naomi Lesmana Raihan Akbar Muhammad Rakhmatul Binti Sulistya Ratna Kusumawati Ratna Kusumawati Ratna Kusumawati Rebekah Setiabudi, Rebekah Rosantia Sarassari S. Soedarsono Sardjono, Lindawati Alim Sawitri Sawitri Semita, I Nyoman Setiawan, Firman Setya Wijoyo, Dhia Lintang Shazia Hafazhah Aulia Silvia Sutandhio Sri Purwaningsih Steven Christian Susianto Sudarmo, Subijanto Marto Sugeng Harijono, Sugeng Terza Aflika Happy Titiek Sulistyowati Titiek Sulistyowati Ummi Maimunah Usman Hadi Vermasari, Naritha Wahyu Setyarini Wahyunitisari, Manik Retno Wardhani, Puspa Wiwin Retnowati Yelvi Levani Yitijuatni Yuani Setiawati Yudayanti, Elprania Credo Yuliati Hood