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All Journal MEDIA KONSERVASI Palapa: Jurnal Study Keislaman dan Ilmu Pendidikan Promotif: Jurnal Kesehatan Masyarakat Forest and Society Pusaka : Jurnal Khazanah Keagamaan Jurnal Menssana Tadabbur: Jurnal Peradaban Islam GEMASSIKA: Jurnal Pengabdian Kepada Masyarakat PRAJA: Jurnal Ilmiah Pemerintahan Indonesian Journal of Pharmaceutical and Clinical Research Jurist-Diction Journal SAGO Gizi dan Kesehatan Journal of English Language and Education Jurnal EMPATI (Edukasi Masyarakat, Pengabdian dan Bakti) Sibatik Journal : Jurnal Ilmiah Bidang Sosial, Ekonomi, Budaya, Teknologi, Dan Pendidikan Jurnal Interkom : Jurnal Publikasi Ilmiah Bidang Teknologi Informasi dan Komunikasi Dirgamaya: Jurnal Manajemen dan Sistem Informasi Jurnal Informasi Sains dan Teknologi (ISAINTEK) INOTEK Journal of International Conference Proceedings Prosiding University Research Colloquium MASALIQ: Jurnal Pendidikan dan Sains Jurnal PADE: Pengabdian & Edukasi Al-DYAS : Jurnal Inovasi dan Pengabdian kepada Masyarakat Jurnal Litek : Jurnal Listrik Telekomunikasi Elektronika Jurnal Kebidanan, Keperawatan dan Kesehatan (J-BIKES) Nusantara Scientific Medical Research Journal Jurnal Penelitian Kehutanan Wallacea Journal of Pharmaceutical and Sciences. Nasuwakes : Jurnal Kesehatan Ilmiah Jurnal Bakti Nusantara J-Proteksion : Jurnal Kajian Ilmiah dan Teknologi Teknik Mesin
Nasri Nasri, Nasri
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Antidiarrheal Effect of Lactobacillus fermentum Isolated from Dengke Naniura on Escherichia coli-induced Rats Nasri, Nasri; Harahap, Urip; Silalahi, Jansen; Satria, Denny
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 5 No. 1 (2022): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v5i1.6478

Abstract

Diarrhea is discharge of abnormal and liquid stool with a frequency of 3-4 daily which caused by pathogenic organisms such as Escherichia coli, and other. Dengke Naniura is a traditional Batak Toba food that can produce probiotics (Lactobacillus fermentum). Probiotics are defined as live microorganisms that confer a health benefit on the host. Nutritional supplements combined between probiotics and prebiotics are called synbiotics, The purpose of this study was to analyze the preventive effect of diarrhea in rats given L.fermentum for 21 days. The preventive effect of diarrhea test begins with the giving of L.fermentum from day 1 to day 21. From day 7 to day 14 rats were induced with E.coli. Weight of the rats, stool consistency, onset of diarrhea, frequency of diarrhea, and duration of diarrhea were observed. The results of the observation that weight of rats in the L.fermentum group increased compared to group 1 (p<0.05). Consistency stool is soft (massless). Onset of diarrhea on day 1 after induced of E.coli in the group 1. Frequency of diarrhea increased to 9.25 ± 0.50 times on day 14 (group 1). And diarrhea occurs for 10 days. Conclusion L.fermentum showed a preventive effect of diarrhea in rats induced E.coli.
Antibacterial Activity Test of Malacca Leaf Extract (Phyllanthus emblica) Against Staphylococcus aureus and Staphylococcus epidermidis Bacteria Ridwanto, Ridwanto; Aprilia, Hijjatun; Rani, Zulmai; Putri Aisyia Fauzi, Ziza; Kaban, Vera Estefania; Nasri, Nasri
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 7 No. 1 (2024): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v7i1.17912

Abstract

Antibacterials are substances that can interfere with the growth or even kill bacteria and have the side effect of antibacterial resistance. One effort to reduce resistance is choosing to use natural bacterial ingredients. One plant that can potentially contain antibacterial activity is malacca leaves (Phyllanthus emblica). The contents of this plant include flavonoids, alkaloids, tannins, saponins, and steroids/triterpenoids. This research aimed to prove the antibacterial activity test of malacca leaf extract. The stages in this research included phytochemical screening and testing the antibacterial activity of ethanol extract from Malacca leaves for Staphylococcus aureus and Staphylococcus epidermidis bacteria using the diffusion method using paper discs. The characteristics of malacca leaf simplicia obtained were water content of 4.6%, water-soluble content of 28%, ethanol-soluble essence content of 23.33%, total ash content of 2.00%, and insoluble ash content of 0.5%. The results of phytochemical screening showed the presence of flavonoids, saponins, tannins, glycosides, and steroids/triterpenoids. The antibacterial test results of malacca leaf extract at concentrations of 500 mg/ml, 400 mg/ml, 300 mg/ml, and 200 mg/ml have an antibacterial effect against Staphylococcus aureus and Staphylococcus epidermidis, and there is no difference in the effectiveness of the inhibitor against gram-positive and negative grams.
Pengembangan Formulasi Krim Pelembab Kulit Berbasis Ekstrak Sari Buah Mangga (Mangifera indica L.): Pendekatan Fungsional dan Kosmetika Alami Suci, Nurul; Khairunnisa, Lia; Nasri, Nasri; Kaban, Vera Estefania
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 7 No. 2 (2024): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v7i2.18220

Abstract

This study aimed to develop a formulation of mango fruit juice (Mangifera indica L.) as a moisturizing agent in the form of hand cream. The main component of mango, sucrose, has the ability to attract moisture from the air due to its hydroxyl groups, which helps reduce water evaporation from the skin. Mango juice was obtained by blending the mango pulp using a juicer, followed by the addition of 0.1% sodium metabisulfite as an antioxidant. The extract was then concentrated using a freeze-drying technique at -40°C and 2 atm pressure. The cream formulation developed was an oil-in-water (m/a) emulsion type, with mango fruit juice concentrations of 2.5%, 5%, 7.5%, and 10%. These were compared to cream containing 2% glycerin and a blank formulation. Various tests were conducted to evaluate the physical quality of the cream, including homogeneity, pH, stability, emulsion type, and irritation tests using a moisture-checker. The results showed that mango fruit juice was successfully formulated into a homogeneous m/a cream, with a pH ranging from 5.55 to 7.04, and remained stable for up to 12 weeks of storage. The cream formulated with mango juice was proven to increase skin moisture without causing irritation. The higher the concentration of mango fruit juice, the greater the moisturizing effect. The 2.5% concentration provided a moisturizing effect comparable to cream containing 2% glycerin. The best moisturizing effect was achieved at a 10% concentration, which increased skin moisture by up to 14.4% after 4 weeks of use. This mango juice is effectively used in m/a type creams as a skin moisturizer. Keyword: Mango fruit juice, cream, skin moisturizer
How Climate Change Disrupts Mango Phenology and Affects Fruit Production Hamzah, Andi Siady; Ngakan, Putu Oka; Kaimuddin, Kaimuddin; Nasri, Nasri; Putra, Putu Supadma; Mas'ud, Wardiman
Jurnal Penelitian Kehutanan Wallacea Vol. 14 No. 2 (2025)
Publisher : Foresty Faculty of Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24259/jpkwallacea.v14i2.47504

Abstract

Climatic elements are limiting factors for plants; therefore, climate change can impact the phenology of plants. This study aims to determine the impact of climate change on the reproductive phenology of four local mango cultivars on Sulawesi Island, Indonesia. Data were collected during 2013 and 2014 by observing and recording the production of vegetative shoots, generative shoots, and fruits from the trees of each mango cultivar weekly. To assess the impact of seasonal change on fruit quality, the weight and sugar level of the ripe fruits in each cultivar were measured. Climate data were obtained from the National Centers for Environmental Prediction and the Indonesian Agency for Meteorology, Climatology, and Geophysics Region IV, Makassar. Results show that from 1979 until 2014, the climate in the study site changed from type D to type C according to the Schmidt-Ferguson Climate Classification method, indicating that the wet season became longer. Following climate change, the reproductive phenology of the four mango cultivars also changed from once to twice annually, whereby the flush of vegetative and reproductive shoots that appeared during the first period in March did not successfully develop into mature fruit but developed following the second period in July. The change of season also impacted the quality of the mangoes, as fruit produced during the longer dry season had higher sugar levels than those produced during the shorter dry season.
PROTOTYPE ALAT PENDETEKSI GAS BERBAHAYA DI KAMAR MESIN UNTUK MENJAGA KESELAMATAN ABK BERBASIS WEMOS D1 DI KAPAL MT PLAJU Purnama Dewi, Nanda; Nasri, Nasri; Purwanto, Sigit; Retno Gunarti, Monika; Dai Robbi, Shofa
SIBATIK JOURNAL: Jurnal Ilmiah Bidang Sosial, Ekonomi, Budaya, Teknologi, Dan Pendidikan Vol. 5 No. 1 (2025)
Publisher : Penerbit Lafadz Jaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/sibatik.v5i1.4194

Abstract

Enclosed spaces in ship engine rooms pose significant risks due to toxic gas accumulation like carbon monoxide and carbon dioxide, contributing to maritime fatalities. This research aimed to develop a Wemos D1-based prototype for real-time hazardous gas detection to enhance crew safety on MT Plaju tanker. Experimental prototype development employed ADDIE model with static and dynamic testing on MQ-135 sensor, buzzer, LED, and WiFi web monitoring. Population comprised four main holes (A-D) in engine room enclosed spaces, sampled through 20 measurements during 12-month sea practice. Instruments included Arduino IDE for programming and Excel for regression linear analysis with <5% calibration error. Results showed average CO detection at 5.4 ppm and CO2 at 406 ppm, with alarm response under 6 seconds exceeding 30% threshold, achieving 95% accuracy in high humidity and vibration conditions. The prototype demonstrated superior WiFi connectivity over previous ATMega328P systems, reducing hazard zones by 40%. In conclusion, this cost-effective IoT solution validates hardware reliability for Indonesian maritime operations, recommending multi-gas sensor integration for industrial scaling.
Sosialisasi Penggunaan Obat dengan Cara Khusus di Kecamatan Percut Sei Tuan, Deli Serdang, Sumatera Utara Rani, Zulmai; Dalimunthe, Gabena Indrayani; Nasution, Haris Munandar; Yuniarti, Rafita; Lubis, Minda Sari; Pulungan, Ainil Fithri; Kaban, Vera Estefania; Nasri, Nasri; Utami, Dinda Sari
Jurnal Bakti Nusantara Vol. 3 No. 1 (2025): Jurnal Bakti Nusantara
Publisher : Pustaka Media Publishing

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.63763/jutira.v3i1.107

Abstract

Seiring dengan kemajuan teknologi, semakin banyak sediaan farmasi yang dikembangkan. Ini termasuk inhaler, pen insulin, suppositoria, obat mata, telinga, dan lain-lain.  Tetes mata (oculoguttae), salep mata (oculenta), pencuci mata (colyria), dan bentuk lain dari obat mata dikenal sebagai optalmika. Penggunaan obat dengan alat khusus ini dapat menimbulkan efek samping dan hal yang tidak diiinginkan jika tidak digunakan secara benar. Hal ini disebabkan kurangnya informasi tentang penggunaan obat, cara penyimpanan dan lama penyimpanan obat pada masyarakat di Desa Kolam. Penyuluhan mengenai penggunaan obat dengan alat khusus ini untuk mencegah terjadinya efek samping atau hal yang tidak diinginkan. Kegiatan pengabdian dilakukan di Dusun I Desa Kolam, masyarakat dilibatkan dalam kegiatan yang dibantu oleh Kader Posyandu Kamboja dan pihak terkait lainnya.  Penyuluhan ini menggunakan ceramah, diskusi, dan pemutaran video. Selain itu, untuk mengetahui seberapa puas masyarakat dengan materi yang disampaikan, dan kuesioner. Pengabdian masyarakat yang dilakukan tim diharapkan dapat memberikan pemahaman yang baik kepada masyarakat, serta cara penggunaan obat dengan alat khusus secara tepat dan benar. Informasi akan pentingnya penggunaan obat, cara penyimpanan obat dan lama penyimpanan obat setelah kemasan dibuka. Hal ini akan berhubungan dengan efek terapi yang diharapkan serta untuk mencegah terjadinya efek samping obat.
Ecological Disaster in Northern Sumatra: How Extreme Rainfall and Land-Cover Disturbance Triggered Widespread Flash Flooding Nasri, Nasri; Nursaputra, Munajat; Arif, Abdur Rahman; Dwiyani, Risye; Chania, Lady; Agastya, Ida Bagus Oka; Arif, Dian Adhetya Arif
Jurnal Penelitian Kehutanan Wallacea Vol. 14 No. 2 (2025)
Publisher : Foresty Faculty of Hasanuddin University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24259/jpkwallacea.v14i2.48907

Abstract

In November 2025, Northern Sumatra experienced one of the most extreme flood disasters in recent history, triggered by a rare combination of sustained high-intensity rainfall and long-term land-cover disturbance. Using satellite-based rainfall estimates, historical rainfall records, and land-cover change analysis, this study examines the spatial and temporal dynamics of the event. The rainfall produced over 950 mm within four days, with daily accumulation exceeding 390 mm and hourly peaks surpassing 40 mm/hr. Statistical analysis using the Generalized Extreme Value (GEV) distribution estimated a return period of approximately 192 years for the daily maximum. Land-cover analysis revealed extensive deforestation between 1990 and 2024, including in designated protection and conservation forest zones. Flood impacts were concentrated in watersheds with high forest loss and recent land disturbance, particularly in Aceh and North Sumatra. This study highlights how compounding hydroclimatic extremes and upstream land degradation can significantly amplify flood risk. The findings underscore the importance of integrating forest conservation and multi-day rainfall indicators into regional flood risk assessments and early warning systems.
ANTIOXIDANT ACTIVITY OF HYDROALCOHOLIC EXTRACT OF GREEN GEDI LEAVES (Abelmoschus manihot L.) USING CUPRAC (CUPRIC ION REDUCING ANTIOXIDANT CAPACITY) METHOD Kaban, Vera Estefania; Nasri, Nasri; Suci, Nurul; Lubis, Muhammad Fauzan; Rani, Zulmai; Nasution, Haris Munandar
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 8 No. 02 (2025): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v8i02.20644

Abstract

Free radicals induce oxidative stress, which plays a pivotal role in the pathogenesis of various degenerative diseases. Abelmoschus manihot L., locally known as green gedi, is recognized for its rich secondary metabolite content with potential antioxidant properties. This study aimed to evaluate the antioxidant activity of the hydroalcoholic extract of green gedi leaves using the Cupric Ion Reducing Antioxidant Capacity (CUPRAC) method. Extraction was conducted via maceration using a 90% hydroalcoholic solvent, followed by comprehensive phytochemical screening and simplicia characterization. The antioxidant capacity was quantified by determining the IC50 value through linear regression analysis of inhibition percentage versus concentration. Phytochemical analysis confirmed the presence of alkaloids, flavonoids, glycosides, saponins, tannins, and triterpenoids/steroids. The hydroalcoholic extract exhibited "very strong" antioxidant activity, yielding an IC50 value of 41.65 ± 0.30 µg/mL. Although this potency was slightly lower than the pure quercetin standard, it demonstrates a significant capacity for free radical neutralization. These findings underscore the potential of Abelmoschus manihot L. as a robust natural antioxidant source, supporting its further development into phytopharmaceuticals or functional health supplements for the prevention of oxidative stress-related conditions.
FERMENTATION OF BITTER MUSTARD GREENS (Brassica juncea (L.) Czern.: PHYTOCHEMICAL SCREENING, PROXIMATE COMPOSITION, AND ISOLATION OF LACTIC ACID BACTERIA Nasri, Nasri; Cintya, Henni; Haro, Ginda; Silalahi, Jansen; Pakpahan, Gita Asima E.; Sitanggang, Sarah Novia S.; Sefira, Inka
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 8 No. 02 (2025): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v8i02.24242

Abstract

Fermented vegetables are widely consumed functional foods, but scientific data on traditionally fermented bitter mustard greens are still limited. This study aimed to evaluate the phytochemical profile and proximate composition of Brassica juncea after spontaneous fermentation and to isolate lactic acid bacteria (LAB) formed during the process. A laboratory experimental design was applied; bitter mustard greens were spontaneously fermented in brine for seven days at room temperature. Daily changes in pH and organoleptic characteristics were recorded. Phytochemical screening was performed on fresh and fermented samples (leaves, stems, brine). Proximate analysis included moisture, ash, acid-insoluble ash, crude fat, protein, and carbohydrates using AOAC methods. LAB were isolated on MRS–CaCO₃ agar and characterized phenotypically. Fermentation produced a progressive decrease in pH (from 5.0 to 2.9–3.3) accompanied by sour aroma and yellowish discoloration, indicating active lactic acid fermentation. Flavonoids, phenolics, and terpenoids were present in both fresh and fermented samples, although weaker reactions occurred in stems and brine. Proximate analysis revealed very high moisture content (88.76–95.20%), low protein (0.53–0.88%), low fat (5.03–5.50%), and low residual carbohydrates. LAB isolates (ASP-CF, ASP-B, ASP-D) were Gram-positive, catalase-negative, acid-producing, and non-H₂S-forming. In conclusion, traditional spontaneous fermentation of Brassica juncea produces a LAB-dominated fermented product that retains major phytochemical groups and exhibits proximate characteristics typical of fermented vegetables, supporting its potential as a functional food. Further molecular identification of LAB and quantitative metabolite profiling are recommended.
Optimizing Carrageenan-Based Moisturizers: From Kappaphycus alvarezii Extraction to Formulation Suci, Nurul; Rahmi, Alfia; Nasri, Nasri; Kaban, Vera Estefania
Indonesian Journal of Pharmaceutical and Clinical Research Vol. 8 No. 02 (2025): Indonesian Journal of Pharmaceutical and Clinical Research
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/idjpcr.v8i02.18124

Abstract

Carrageenan, a sulfated polysaccharide extracted from red seaweed (Kappaphycus alvarezii), possesses a high water-holding capacity and has been widely investigated for its potential application as a skin moisturizing agent. This study aimed to formulate isolated carrageenan into a topical cream and to evaluate its physicochemical characteristics and moisturizing efficacy. Carrageenan was isolated through sequential soaking, decantation, extraction, isolation, drying, and milling processes. The isolated material was characterized in terms of solubility, viscosity, loss on drying, and Fourier transform infrared (FTIR) spectroscopy. Cream formulations containing carrageenan at concentrations of 2.5%, 5%, 7.5%, and 10% (w/w) were prepared and compared with a 2% glycerin cream and a blank control. Physical quality evaluations included homogeneity, pH, emulsion type, stability testing for 12 weeks, skin irritation assessment, and in vivo moisturizing activity in 18 human volunteers. The isolated carrageenan complied with the requirements of USP XXX. All carrageenan-based creams exhibited acceptable homogeneity, skin-compatible pH, and satisfactory physical stability throughout the storage period. No signs of skin irritation were observed. Moisturizing efficacy increased proportionally with carrageenan concentration, with the 2.5% carrageenan cream demonstrating a moisturizing effect comparable to that of the 2% glycerin formulation. These findings support the potential of carrageenan derived from Kappaphycus alvarezii as an effective natural moisturizing agent in topical cream formulations.
Co-Authors Abdur Rahman Arif, Abdur Rahman Adnan, Naufal Agastya, Ida Bagus Oka Ali, Muhammad Farhan Aminah Dalimunthe Amran Achmad Andriani Andriani Apdian, Donny Aprilia, Hijjatun Ari Sapti Mei Leni Arif, Dian Adhetya Arif Aristiyanto, Aristiyanto Asrianny Asrianny, Asrianny Awalludin, Dudi B.K, Felicia A. Stevanie Bakhri, Asep Samsul Barbyanavy, Dinda Ayu Chania, Lady Cintya, Henni Dai Robbi, Shofa Denny Satria, Denny Dinda Sari Utami Dwilaksana, Chryshnanda Dwiyani, Risye Effendy De Lux Putra, Effendy De Lux Fithri Pulungan, Ainil Gabena Indrayani Dalimunthe Gunarti, Monika Retno Hamzah, Andi Siady Handika, Handika Haris Munandar Nasution Haro, Ginda Herdinata, Guntur Ratih Prestifa Ibrahim Ibrahim Ichsansyah, Ananta Imran, Herry Ipa Sari Kardi Jansen Silalahi Jayawiguna, Rukmanta Kaimuddin Kaimuddin, Kaimuddin Karo Sekali, Elva Swandi Keumala, Cut Ratna Khairunnisa, Lia Koesharyadi, Arif Kusumawati, Elly LATIF, MUH. WAHYUDIN Lubis, Minda Sari lubis, muhammad fauzan Mas'ud, Wardiman Muhammad Nur Muhammad Syahroni Munajat Nursaputra, Munajat Mutmainnah, Aisyah Niakurniawati, Niakurniawati Nilawati, Ika Nopiyanto, yahya eko Nugroho, Azis Nur Amin, Nur Nur Islami, Ina Prihati Nurqalbi, Maftukha Nuzul Wilda, Nuzul Pakpahan, Gita Asima E. Pintauli, Sondang Prawoto, Agus Purnama Dewi, Nanda Putra, Putu Supadma Putu Oka Ngakan Rahman Nur, Abdul Rahmat Gunawan Rahmi, Alfia Raisah Hayati Ratna Keumala, Cut Ratna Ratna Ratna Wilis Retno Gunarti, Monika Rexi, Daniel Ridwanto Ridwanto Rinaldi, Nasrullah Rini Widarti Risma Illa Maulany Robbi , Shofa Dai Robbi, Shofa Dai Rosnita, Windha Rusda, Rusda Sagala, Hasel Untung Bersinar Salmi, Salmi Santoso, Muzi Saprudin Saprudin, Saprudin Sefira, Inka Setiawan, Fredy Eko Sigit Purwanto Sitanggang, Sarah Novia S. Siti Morin Sinaga Suci, Nurul Suhati, Fadly Sulistiyana, Sulistiyana Sutrisno, Sutrisno Syahdar, Fardi Ali Syahputra, Hariyadi Dharmawan Urip Harahap Vera Estefania Kaban Wardana, Gusde Wardono, Sri Wicaksono, Maulana Tegar Yudiana, Yudiana Yudianto, Prima Yudha Yuniarti, Rafita Yusr, Daffa Izaz Rafi Afif Fauzi Zakiah Drajat, Ulfah Ziza Putri Aisyia Fauzi Zulmai Rani