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Iswari Pauzi
Poltekkes Kemenkes Mataram
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Analisis Variasi Infeksi Malaria Terhadap Hasil Pemeriksaan Bilirubin Urine Metode Carik Celup Nila, Intan Mustika; Diarti, Maruni Wiwin; Pauzi, Iswari
Jurnal Analis Medika Biosains (JAMBS) Vol 5, No 2 (2018): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v5i2.152

Abstract

Latar Belakang : Malaria adalah penyakit infeksi parasit yang disebabkan oleh spesies Plasmodium. Infeksi Plasmodium dapat mengakibatkan gejala- gejala klinis seperti penyakit kuning, batuk, muntah terus menerus, gangguan saraf dan urine berwarna coklat. Urine berwarna coklat telah dikaitan dengan hemoglobinuria, myoglobinuria, dan bilirubinuria. Tingkat infeksi tinggi maka semakin banyak eritrosit didestruksi yang kemudian akan meningkatkan kadar bilirubin dalam urine penderita malaria. Tujuan : Mengetahui analisis variasi infeksi malaria terhadap hasil pemeriksaan bilirubin urine metode carik celup. Metode : Penelitian ini merupakan penelitian yang besifat Observasional analitik dengan pendekatan cross sectional, jumlah sampel menggunakan sampel jenuh, teknik pengambilan sampel dengan Non Random Accidental Sampling. Variabel penelitian berupa variasi infeksi malaria, kadar bilirubin urine dan metode carik celup. Data hasil pemeriksaan yang terkumpul menggunakan uji statistik deskriptif. Hasil : Pada 4 pasien positif terinfeksi Plasmodium falciparum (Malaria Tropika) didapatkan hasil negatif bilirubin urine secara kualitatif maupun semi kuantitatif. Pada 3 pasien positif terinfeksi Plasmodium vivax (Malaria Tertiana) didapatkan hasil negatif bilirubin urine secara kualitatif maupun semi kuantitatif. Sedangkan pada 5 pasien positif Malaria mix menunjukkan hasil bilirubin urine 3 pasien secara kualitatif adalah +1 dengan kadar 1-17 mg/dl secara semi kuantitatif metode carik celup. Kesimpulan : Didapatkan hasil negatif bilirubin urine metode carik celup pada infeksi malaria tropika dan malaria tertiana sedangkan pada infeksi malaria mix didapatkan hasil positif bilirubin urine pada 3 sampel.
Analysis of Kidney Function Test Profiles in Relation to the Incidence of Chronic Kidney Failure in Diabetes Mellitus Patients Pauzi, Iswari; Hadi, Aprilia Khairunnisa; Diarti, Maruni Wiwin
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 1 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i1.367

Abstract

Diabetes Mellitus (DM) is one of the most common chronic diseases worldwide and is a leading cause of chronic kidney failure (CKD). Kidney complications in diabetic patients, known as diabetic nephropathy, can lead to CKD. Early detection and monitoring of kidney function are crucial in managing patients with DM to prevent or delay the progression of CKD. Kidney function tests such as urea levels, creatinine levels, and uric acid levels can be used to assess kidney condition and the risk of CKD development. To analyze the profile of kidney function tests in cases of chronic kidney failure in patients with diabetes mellitus. This study is an Analytical Observational research. The number of samples of diabetes mellitus patients with chronic kidney failure is 52 patients who underwent kidney function profile examinations including urea, creatinine, and uric acid. The data analysis used is descriptive analysis. Based on the obtained data, it was found that during this study, the respondents were predominantly male, with 36 individuals (69.2%), and in terms of age group, the respondents were predominantly in the 61-70 age group, with 15 individuals (28.8%). The average values of urea, creatinine, and uric acid in 52 samples of diabetes mellitus patients with chronic kidney failure were 123.05 mg/dl for urea, 4.85 mg/dl for creatinine, and 8.35 mg/dl for uric acid. The characteristics of the respondents based on gender were predominantly male, and the characteristics based on age were predominantly within the 61-70 year age group. The analysis results showed an increase in the values of kidney function test profiles (urea, creatinine, and uric acid) in diabetic patients with chronic kidney failure. It is evident from the average results of each kidney function test parameter that the average levels exceeded the normal range. 
Description Of Hepatitis Infection With Differential Leukocyte Count In Mataram City Hospital Urip, Urip; Sitiana, Nining; Pauzi, Iswari; Jiwantarum, Yunan
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 1 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i1.364

Abstract

Hepatitis is an infectious disease characterized by increased levels of liver enzymes due to damage or disruption of the liver membrane. Hepatitis consists of various viruses. Hepatitis A is caused by infection with the hepatitis A virus (HAV), hepatitis B is caused by infection with the hepatitis B virus (HBV), hepatitis D is caused by infection with the hepatitis D virus (HDV), and hepatitis E is caused by infection with the hepatitis E virus (HEV). The objectives of this research are to find out the relationship between the type of Hepatitis infection and the Differential Count of leukocytes in the Mataram City Regional Hospital. The method of this research is Observational Analytical. The sampling technique in this research is the Purposive Sampling technique. The sample used in this research is the serum of Hepatitis sufferers. The population in this study is medical record data of hepatitis sufferers who underwent leukocyte type examination from January-December 2022 in Mataram City Regional Hospital, The number of samples obtained was 59 samples with types of Hepatitis A, B, and C. Data analysis used descriptive frequency. The results of this research were that the average results for the type of leukocyte Hepatitis B (HBV) mean basophils were 0.15%, eosinophils 1.89%, 75.72% neutrophils, 16.24% lymphocytes, and 6.02% monocytes. C (HCV) means basophils 0%, eosinophils 1.5%, neutrophils 82%, lymphocytes 10%, and monocytes 6%. This research concludes that there is an increase in neutrophils and a decrease in lymphocytes.  
Hubungan Titer Widal Dengan Jumlah Limfosit Dan Trombosit Pada Pasien Demam Typhoid Di Puskesmas Gunungsari Lombok Barat Fitriyani, Fitriyani; Pauzi, Iswari; Jiwantoro, Yudha Anggit
Jurnal Analis Medika Biosains (JAMBS) Vol 8, No 2 (2021): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v8i2.245

Abstract

Demam typhoid merupakan infeksi bakteri yang disebabkan oleh Salmonella typhi. Infeksi Salmonella typhi bersifat bakterimia yang masuk ke dalam usus halus kemudian menyebar ke sumsum tulang. Diagnosis Samonella typhi menggunakan uji widal dan pemeriksaan darah rutin. Uji Widal dan pemeriksaan darah rutin untuk melihat mekanisme tubuh terhadap limfosit dan trombosit yang diproduksi di sumsum tulang dan berfungsi sebagai pertahanan tubuh terhadap adanya infeksi. Bila bakteri ini sampai ke sumsum tulang maka akan menghambat pembentukan limfosit dan trombosit. Hal ini juga disebabkan adanya endotoksin dari bakteri sehingga pada kasus demam typhoid terjadinya limfositosis dan trombositopenia. Tujuan penelitian: Mengetahui hubungan titer widal dengan jumlah limfosit dan trombosit pada pasien demam typhoid. Metode penelitian: Observasional Analitik. Jumlah sampel yang digunakan sebanyak 24 sampel dengan menggunakan data primer. Data yang dikumpulkan berupa titer widal dengan jumlah limfosit dan trombosit. Kemudian diolah menggunakan uji statistik Korelasi Person. Hasil Penelitian: Rerata limfosit pada antigen O dengan titer 1/160 adalah 24,84%, titer 1/320 adalah 43,95%, rerata trombosit dengan titer 1/160 adalah 312.000 µL dan titer 1/320 adalah 230.750 µL. Sedangkan pada antigen H rerata jumlah limfosit dengan titer 1/160 adalah  35,48% dan titer 1/320 adalah 39,86%. Rerata jumlah trombosit dengan titer 1/160 adalah 196.670 µL dan titer 1/320 adalah 158.000 µL. Hasil uji statistik p>0,05. Kesimpulan: Tidak terdapat hubungan titer widal dengan jumlah limfosit dan trombosit pada pasien demam typhoid di Puskesmas Gunungsari Lombok Barat.
Resistance Analysis Of Several Antibiotics in Samples of Clinical Isolates With Salmonellosis Wahyuni, Shohifatul; Pauzi, Iswari; Jiwintarum, Yunan; Fihiruddin, Fihiruddin
Jurnal Analis Medika Biosains (JAMBS) Vol 11, No 1 (2024): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v11i1.357

Abstract

Typhus is a systemic infection caused by Salmonella typhi bacteria, which is usually transmitted through contaminated food or drink, usually treated with antibiotics. Inappropriate use of antibiotics causes various problems, one of which causes resistance. This resistance problem has become a global problem, including in Indonesia where there is an increase in bacterial resistance from 2013 which is 40%, 2016 as much as 60% and in 2019 reached 60.4%, due to irrational use of antibiotics so that bacteria become resistant to drugs. This study aims to determine the description of resistance to several antibiotics in clinical isolates of patients with Salmonellosis This study is a pre-experimental study, with a cross sectional approach. The samples used were pure isolates of Salmonella typhi bacteria obtained from blood samples of Salmonellosis patients, then tested for resistance with 5 different types of antibiotics (Ciprofloxacin, Amoxicillin, Levofloxacin, Cefotaxime and Sulfamethoxazolle-trimethopim) with the disk method (Kearby Beaure). The number of experimental units is 25 units, with the number of replications is 5 replications. The results showed that the five types of antibiotics were sensitive to Salmonella typhi bacteria with the highest antibiotic sensitivity being Ciprofloxacin while the antibiotic that had the lowest sensitivity was Amoxicillin. From the results, it can be concluded that the resistance test of the five antibiotics (Ciprofloxacin, Amoxicillin, Levofloxacin, Cefotaxime and Sulfamethoxazolle-trimethopim) is sensitive. 
Effects of Carbohydrate Diet Programs on Urine Ketones Positiveness with Long Time on a Diet 1 Year, 2 Years and 3 Years Maya, Dyah Astining; Pauzi, Iswari; Zaetun, Siti; Jiwantoro, Yudha Anggit
Jurnal Analis Medika Biosains (JAMBS) Vol 10, No 1 (2023): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v10i1.303

Abstract

Carbohydrate diet is a diet pattern that reduces carbohydrate consumption. Therefore, the body will use fat as an alternative energy source. The continuous use of fat causes the accumulation of fatty acids so that it often causes ketone positivity in the urine. Objective : Find out the effect of a carbohydrate diet program on the positivity of urine ketones. Method : This research is an analytic observational study with a cross sectional approach. The sample used was urine from respondents who had been on a carbohydrate diet for 1 year, 2 years and 3 years, then urine ketones were examined using the dipstick method. Data analysis was carried out using the Chi-Square test with a confidence value (α = 0.05). Result : The sample in this study amounted to 45 samples, with a total of 23 samples of positive ketones and 22 samples of negative ketones. The results of the Chi Square test obtained an Asymp. sig value of 0.009 <0.05 (α) which indicates that the carbohydrate diet program has a significant effect on the positivity of urine ketones.
Creativity Profile Of Medical Laboratory Technology Students In Medical Instrumentation Learning pauzi, Iswari; Hakim, Aliefmam; Doyan, Aris; Hadiprayitno, Gito; Rokhmat, Joni; Sukarso, A.A
Jurnal Analis Medika Biosains (JAMBS) Vol 10, No 2 (2023): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v10i2.322

Abstract

The aim of the study was to describe the creativity profile of students of the Applied Undergraduate Study Program of Medical Laboratory Technology, Health Polytechnic, Ministry of Health, Mataram. The research method used is descriptive research. Data was collected through a questionnaire made using the Google form and then distributed to research respondents totaling 52 students. The data analysis technique used is descriptive analysis using the percentage of each indicator. The results showed that students' critical thinking skills were low on indicators of providing further explanations and drawing conclusions, and creative thinking skills were low for students to think fluently and originally.
Hubungan antara Nilai Hemoglobin Glikasi (HbA1c) Dengan Kadar Ureum dan Kreatinin pada Pasien Diabetes Melitus Tipe 2 Di RSUD Praya Suda Adnyana Yoga, I Gede; Jiwintarum, Yunan; Urip, Urip; Pauzi, Iswari
Jurnal Borneo Cendekia Vol 9 No 1 (2025): Jurnal Borneo Cendekia
Publisher : STIKES Borneo Cendekia Medika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54411/jbc.v9i1.621

Abstract

Diabetes melitus (DM) menjadi persoalan kesehatan yang serius di Nusa Tenggara Barat (NTB) dan dapat menimbulkan komplikasi jangka panjang, seperti nefropati diabetik yang menyebabkan gagal ginjal. Kondisi hiperglikemia kronis pada penderita diabetes menyebabkan perubahan pada struktur dan fungsi ginjal melalui mekanisme seperti produk akhir glikasi lanjut (AGEs), stres oksidatif, dan proses inflamasi. Oleh karenanya, pengendalian glikemik yang tepat sangat penting untuk mencegah timbulnya penyakit ginjal kronis (PGK) pada pasien diabetes. Penelitian kuantitatif dengan rancangan cross-sectional ini bertujuan untuk mengevaluasi hubungan antara kadar HbA1c dan kadar ureum serta kreatinin pada pasien dengan DM tipe 2 di RSUD Praya. Sebanyak 92 sampel dipilih menggunakan teknik purposive sampling dari data rekam medis sekunder. Analisis korelasi Spearman digunakan untuk menilai hubungan antar variabel tersebut. Mayoritas sampel adalah pria (52,2%) dan sebagian besar menunjukkan peningkatan kadar glukosa (70,7%). Dari sampel tersebut, 67,4% memiliki kadar HbA1c lebih dari 7%, sementara kebanyakan memiliki kadar ureum normal (60,9%) dan kreatinin normal (81,5%). Hasil analisis korelasi tidak menunjukkan hubungan signifikan antara kadar HbA1c dengan ureum (p=0,127; koefisien korelasi=0,160) maupun dengan kreatinin (p=0,803; koefisien korelasi=0,026). Tidak terdapat hubungan yang bermakna antara kadar HbA1c dan kadar ureum maupun kreatinin. Hal ini mengindikasikan bahwa nilai HbA1c tidak mencerminkan secara signifikan penurunan fungsi ginjal. Oleh sebab itu, pemantauan glikemik pada pasien diabetes perlu dilengkapi dengan pemeriksaan kadar ureum dan kreatinin secara rutin untuk memperoleh gambaran menyeluruh mengenai fungsi ginjal.
Hubungan Kadar Kreatinin Dengan Hemoglobin Pada Pasien Gagal Ginjal Kronik Sebagai Rujukan Terapi Erythropoietin (EPO) Tandi Manu, Thomas; Zaena Safitri, Trysia; Urip, Urip; Pauzi, Iswari; Khusuma, Ari
Indonesian Health Issue Vol. 4 No. 2 (2025): AGUSTUS
Publisher : Indonesian Journal Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47134/inhis.v4i2.132

Abstract

Background: Chronic kidney disease (CKD) is a common condition and a global health problem with various causes that lead to a gradual decline in kidney function, resulting in increased creatinine levels. This condition reduces the production of the hormone erythropoietin (EPO), which stimulates the bone marrow to produce red blood cells, leading to decreased hemoglobin levels and resulting in anemia. Erythropoietin (EPO) therapy represents a primary therapeutic option for the management of anemia in patients with chronic kidney disease (CKD) PurposeTo determine the relationship between creatinine and hemoglobin levels in chronic kidney disease patients as a reference for erythropoietin (EPO) therapy. Methods: This study employed an analytical observational method with a cross-sectional approach by reviewing medical record data. The sample consisted of 56 patients obtained through total sampling. The data were analyzed using the Pearson correlation test. Results: The average creatinine level was 9.92 mg/dL, and the average hemoglobin (Hb) level was 7.96 g/dL. Pearson correlation analysis between creatinine and hemoglobin levels in patients receiving erythropoietin (EPO) therapy showed a statistically significant result with a p-value of 0.001 (<0.05) and a moderate negative correlation (r = -0.436). Conclusion: A significant negative correlation was found between creatinine and hemoglobin levels in patients undergoing EPO therapy, indicating that higher creatinine levels tend to be associated with lower hemoglobin concentrations.
Differences in Blood Glucose Levels Before and After the Consumption of Sweet Tea in People in Marong Village Aprilla, Annisa Suci; Diarti, Maruni Wiwin; Pauzi, Iswari; Jiwintarum, Yunan
Jurnal Analis Medika Biosains (JAMBS) Vol 12, No 2 (2025): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jambs.v12i2.454

Abstract

Blood glucose is the body's main energy source and is greatly influenced by the consumption patterns of food and beverages, especially those containing sugar. Uncontrolled increases in blood glucose levels can lead to metabolic disorders such as Diabetes Mellitus. Consumption of sweetened tea containing added sugar can cause a rapid spike in blood glucose levels, especially when consumed regularly and in excessive amounts. The purpose of this study is to find out the difference in blood glucose levels before and after sweet tea consumption in the Marong Village community. This study uses a pre-experimental design with a one-group pretest-posttest approach. A total of 16 respondents were selected using the purposive sampling technique. Blood glucose levels were checked before and two hours after the consumption of sweet tea using the POCT (Point of Care Testing) tool. Data were analyzed using a statistical paired sample t-test. The results of the study showed obtained the average blood glucose level before the consumption of sweet tea was 88.3 mg/dL, and after consumption was 97.3 mg/dL, with an average difference of 8.3 mg/dL. The results of the paired sample t-test showed a significance value of 0.000 (p < 0.05), which means that there is a statistically significant difference. This study concludes that the consumption of sweet tea has a significant influence on increasing blood glucose levels.  
Co-Authors A.A Sukarso Agus Muliadi Agus Muliadi Aliefmam Hakim Anam, Haerul Anaz, Haerul Aprilla, Annisa Suci Ari Khusuma Aris Doyan Aris Doyan Asrorul Makmur Azizi Ayu Rosita Bachtiar Ardiansyah Bachtiar Ardiansyah Baiq Eliya Yusrina Eliya Dektra, I Made Putra Pramaditya Dera Suci Elmaria Dewi, Lale Budi Kusuma Dewi, Ni Made Uci Pramesthy Dyah Astining Maya Erlin Yustin Tatontos Erna Kristinawati Ersandhi Resnhaleksmana Ershandi Resnhaleksmana Faiza Waziran Mulyadi Farhataini, Annisa Faylori, Adelia Yusnita Fihiruddin, Fihiruddin Fitriyani Fitriyani Fitriyani Fitriyani Gito Hadiprayitno Gito Hadiprayitno Hadi, Aprilia Khairunnisa Hakim, Aliefmam Hamidi Hamidi Haryanti, Alya Helenia Ananda Feriska Felanis I Gusti Ayu Nyoman Danuyanti I Ketut Swirya Jaya I Ketut Swiryajaya I Komang Agusjaya Mataram, I Komang Agusjaya IGAN Danuyanti Intan Mustika Nila Jiwantarum, Yunan Joni Rokhmat Joni Rokhmat Laelin Hijriyani Lalu Srigede, Lalu Mahayani, I Gusti Ayu Putu Sachita Maruni wiwin Danuarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maya, Dyah Astining Maya, Kadek Melyana Nurul Widiawati Miftahul Aini, Miftahul Mira Pramesty Cahyaningtyas Muh. Zaini Hasanul Muttaqin Muhammad Sarjan Muhammad Sarjan Muhammad Yamin Muhammad Yamin MULIA RASYIDI Naning Fitri Yuliatrik Ni Putu Agustini Ni Putu Karunia Ekayani Nila, Intan Mustika Nurul Inayati Nurul Inayati Pusaka, Semerdanta Rahmani, Putri Ziddanur RAI WIADNYA, IDA BAGUS Resnhaleksmana, Ersandhi Rindu Rahmatiah Rindu Rahmatiah Rohmi Sahputri, Maulidia Rohmiati Septiawan, Dandi Shohifatul Wahyuni Siti Malika Amini Siti Rif’ah Sabariah Siti Zaetun Siti Zaetun, Siti Sitiana, Nining St. Halimatussya’diah Suda Adnyana Yoga, I Gede Sudarmi Sudarmi Sudirman Sudirman Sudirman Sudirman Sukarso, A.A Tasya, Rabaika Monica Thomas Tandi Manu Urip Urip Urip Urip Urip Urip Urip, Urip Wahyuni, Shohifatul Yudha Anggit Yudha Anggit Jiwantoro Yuli Laraeni Yunan Jiwintarum Yunan Jiwintarum Yunan Jiwintarum Yunita Wardani Yusran Khery Yusran Khery Zaena Safitri, Trysia