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Hubungan Nilai Hematokrit dan Jumlah Trombosit Pada Pasien Suspek DBD IgG dengan IgM Positif di Puskesmas Teratak Anaz, Haerul; Ershandi Resnhaleksmana; Thomas Tandi Manu; Iswari Pauzi
Journal of Indonesia Laboratory Students (JILTS) Vol. 4 No. 2 (2025): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v4i2.263

Abstract

Latar Belakang: Demam Berdarah Dengue (DBD) merupakan penyakit tropis yang masih menjadi salah satu masalah kesehatan masyarakat utama di Indonesia. Pemeriksaan serologis IgG dan IgM membantu membedakan antara infeksi dengue primer dan sekunder. Nilai hematokrit yang meningkat menunjukkan adanya kebocoran plasma, sedangkan penurunan jumlah trombositmenandakan trombositopenia yang umum terjadi pada infeksi dengue. Tujuan Penelitian: untuk mengetahui hubungan nilai hematokrit dan jumlah trombosit pada pasien suspek DBD dengan antibodi IgG dan IgM positif di Puskesmas Teratak. Tujuan Penelitian: untuk mengetahui hubungan nilai hematokrit dan jumlah trombosit pada pasiensuspek DBD dengan antibodi IgG dan IgM positif di Puskesmas Teratak. Metode Penelitian: Penelitian dilakukan dengan desain observasional analitik menggunakan pendekatan cross-sectional pada 33 pasien dengan Teknik pengambilan sampel secara purposive sampling. Data dianalisis menggunakan uji korelasi Pearson Product Moment. Hasil Penelitian: Rerata nilai hematokrit pasien adalah 39,0%, sedangkan rerata jumlah trombosit adalah 132.969/µL. dengan p-value 0,847 > 0,05. Kesimpulan: Tidak terdapat hubungan antara nilai hematokrit dan Jumlah Trombosit pada pasien suspek DBD dengan IgG dan IgM Positif.
Analysis of the Nutritional Content of Processed "TOKEN" for Pregnant Women with CED and Anemia Iswari Pauzi; Yudha Anggit Jiwantoro; Ni Putu Karunia Ekayani; Ni Putu Dian Ayu Anggraeni
Jurnal Penelitian Pendidikan IPA Vol 10 No 8 (2024): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i8.7939

Abstract

Malnutrition in pregnant women often occurs in developing countries, including chronic energy deficiency (CED) and micronutrient deficiencies. The aim of this research is to analyze tuna and potato content using proximate analysis and acceptance testing using sensory testing. This type of research is Research and Development, namely the method used to produce certain products and increase the effectiveness of these products. This development research uses a quantitative approach in collecting and analyzing data on mixed tuna and potato. Addition tuna flour and potato flour with the highest average value of 3.84 (like) at the treatment level with the addition of tuna flour and potato flour (25:15%). With a nutrient content of 62.6% water, 4.7% ash content, 9.28% protein, 10.64% fat, 12.75% carbohydrates, and 13.2% Fe content. The high of nutrient, protein, and Fe can be used as a protein source for pregnant women With CED and Anemia
Etika Lingkungan dalam Pembelajaran IPA Berbasis Ekowisata Muh. Zaini Hasanul Muttaqin; Muhammad Sarjan; Joni Rokhmat; Agus Muliadi; Asrorul Azizi; Bachtiar Ardiansyah; Hamidi Hamidi; Iswari Pauzi; Muhammad Yamin; Mulia Rasyidi; Rindu Rahmatiah; Sudirman Sudirman; Yusran Khery
Lambda: Jurnal Ilmiah Pendidikan MIPA dan Aplikasinya Vol. 2 No. 3 (2022): Lambda
Publisher : Lembaga Bale Literasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58218/lambda.v2i3.296

Abstract

This article aims to examine the concept of environmental ethics in ecotourism-based science learning. In conventional education, the educational process only focuses on knowledge (cognitive) while the attitude aspect only gets a very small portion. Environmental ethics in ecotourism-based science learning is expected to integrate various science concepts and contextual science learning objectives with the ecotourism concept, so that the formation of environmental care characters in students and the implementation of ESD can be realized optimally. This research uses literature study method. The data used in this study were sourced from scientific articles (national and international, science textbooks (SD, SMP and SMK), reference books, and literature reviews related to the concepts studied. Based on the above reviews, it can be concluded that the concept of environmental ethics that mostly presented in science learning materials at all levels of primary and secondary education dominated by anthropocentrism theory, while the concept of ecotourism is mostly presented at the vocational level with the Tourism Expertise Program.
Differences in Examination Result of Direction And indirect Low Density Lipoprotein Levels (Several Formulas) in Dyslipidemia Patients AT RSUD DR. R. Soedjono Selong Siti Malika Amini; Iswari Pauzi; Erlin Yustin Tatontos; Maruni Wiwin Diarti
Journal of Indonesia Laboratory Students (JILTS) Vol. 5 No. 1 (2026): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v5i1.177

Abstract

Latar Belakang: Dislipidemia merupakan suatu kelainan metabolisme lipid yang ditandai dengan ketidak seimbangan salah satu atau lebih dari empat komponen profil lipid.. Deteksi dini kadar LDL pada kelompok pasien dengan faktor risiko penyakit kardiovaskuler memungkinkan terapi dan tindakan pencegahan dapat dilaksanakan lebih dini. National Cholesterol Education Program-Adult Treatment Panel (NCEP-ATP) merekomendasikan pengukuran LDL sebagai kriteria primer diagnosis penyakit dislipidemia. Pemeriksaan LDL dapat dilakukan dengan metode direk dan indirek. Pemeriksaan LDL metode direk dilakukan secara terbatas di laboratorium di negara berkembang karena biayanya yang masih cukup mahal. Sedangkan pemeriksaan LDL metode indirek dapat dilakukan dengan menggunakan formula hitung sehingga banyak digunakan sebagai alternatif pengganti LDL metode direk. Tujuan: Mengidentifkasi perbedaan hasil pemeriksaan kadar LDL direk dan indirek (menggunakan beberapa formula) pada pasien dislipidemia di RSUD dr. R. Soedjono Selong Metode: Jenis penelitian observasional analitik  dengan pendekatan cross sectional. Sampel yang digunakan adalah data skunder hasil pemeriksaan profil lipid pasien yang menunjukkan hasil dislipidemia dari populasi pasien yang melakukan pemeriksaan profil lipid bulan oktober 2023 – April 2024 di Laboratorium RSUD dr. R. Soedjono selong. Metode pengambilan sampel adalah metode total sampling dengan jumlah 34 sampel dan dianalisis menggunakan uji one way Anova. Hasil: Hasil peneitian didapatkan rerata kadar LDL metode direk 156 mg/dl,rerata kadar LDL indirek  formula Friedewald 145 mg/dl, rerata kadar LDL indirek formula Chen 189 mg/dl, dan rerata kadar LDL indirek dengan formula Anandaraja 141mg/dl dan rerata kadar LDL indirek dengan formula Hopskin  adalah 152 mg/dl. Uji Anova didapatkan nila sig. (P.value) 0.00 yaitu ≤0.05 yang menunjukkan adanya perbedaan yang bermakna. Kesimpulan: Ada perbedaan yang bermakna antara hasil pemeriksaan kadar LDL direk dan indirek  beberapa formula yaitu formula Friedewald, Chen, Anandaraja, Hopskin pada pasien dislipidemia di RSUD dr. R. Soedjono Selong
Pengaruh Frekuensi Kemoterapi Terhadap Nilai SGPT (Serum Glutamic Pyruvic Transaminase) Pada Pasien Yang Menjalani Kemoterapi IV Berbasis Antrasiklin Mira Pramesty Cahyaningtyas; Urip; Iswari Pauzi; Yunan Jiwintarum
Journal of Indonesia Laboratory Students (JILTS) Vol. 5 No. 1 (2026): Journal of Indonesia Laboratory Students
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32807/jilts.v5i1.287

Abstract

Latar Belakang: Kanker merupakan penyebab utama kematian global, dengan insiden tinggi di Indonesia, termasuk di Provinsi NTB. Kemoterapi berbasis antrasiklin, meskipun efektif, berpotensi menyebabkan hepatotoksisitas yang ditandai dengan peningkatan kadar Serum Glutamic Pyruvic Transaminase (SGPT). Studi terdahulu menunjukkan hubungan antara kemoterapi dan kerusakan hati, namun penelitian spesifik mengenai pengaruh frekuensi siklus kemoterapi antrasiklin terhadap nilai SGPT masih terbatas. Tujuan Penelitian: Mengetahui pengaruh frekuensi kemoterapi terhadap nilai SGPT pada pasien yang menjalani kemoterapi intravena berbasis antrasiklin. Metode Penelitian: Penelitian observasional analitik dengan pendekatan Kohort historis dengan teknik samping jenuh pada pasien yang menjalani kemoterapi antrasiklin di RSUP NTB tahun 2024. Data nilai SGPT sebelum kemoterapi (siklus0) dan setelah siklus 1, 2 dan 3 kemoterapi dikumpulkan dari rekam medik, kemudian dianalisis menggunakan uji statistik untuk membandingkan perbedaan bermakna antar-siklus. Hasil Penelitian: Didapatkan 20 pasien Ca. Ovarium yang memeuhi kriteria inklusi dan didata rata-rata nilai SGPT siklus 0 (27.8 U/L), siklus 1 (26.5 U/L), siklus 2 (22.4 U/L) dan siklus 3 (20.9 U/L). Berdasarkan uji statistik Friedman dengan tingkat kepercayaan 95%=(α=0.05) diatas diketahui nilai Sig.(2-Tailed) sebesar 0.976, karena Nilai Asymp. Sig. > 0.05 maka dapat ditarik kesimpulan tidak ada perbedaan signifikan antara nilai SGPT sebelum dan setelah melakukan kemoterapi antrasiklin. Kesimpulan: Tidak ada pengaruh signifikan antara nilai SGPT setelah melakukan kemoterapi antrasiklin mengindikasikan efek kumulatif terhadap hepatotoksisitas. Namun pemantauan fungsi hati secara berkala dan pertimbangan modifikasi dosis tetap perlu diperlukan untuk mengurangi risiko kerusakan hati.
Differences In Hemoglobin Levels In Infected Patients Salmonella Typhi With Salmonella Paratyphi Based On Antibody Titer Laelin Hijriyani; Fihiruddin Fihiruddin; Iswari Pauzi; Ersandhi Resnhaleksmana
Jurnal Analis Medika Biosains (JAMBS) Vol. 13 No. 01 (2026): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Salmonella typhi and Salmonella paratyphi cause the disease known as typhus abdominalis. The pathogenicity that distinguishes Salmonella typhi and Salmonella paratyphi comes from the virulent part of the bacterial capsule. Virulence factors are found on the surface of Salmonella typhi that are not found in Salmonella paratyphi. The toxic effect of Salmonella that suppresses the bone marrow and the presence of bleeding in the intestine can cause anemia, so a supporting examination is needed, one of which is the examination of Hemoglobin levels. The aimt of this study is knowing the difference of hemoglobin levels in patients infected with Salmonella typhi and Salmonella paratyphi based on antibody titer against H antigens: This study used Analytical Observational method with cross-sectional approach. Data obtained from typhoid fever patients from the examination of hemoglobin levels at Patut Patuh Patju Hospital as many as 96 people using secondary data.  "The mean hemoglobin level for Salmonella typhi, Salmonella paratyphi A, and Salmonella paratyphi B was 9.7 g/dL, 12.0 g/dL, and 12.6 g/dL, respectively. At antibody titers of 1/160 and 1/320, the mean hemoglobin levels for S. typhi were 10.5 g/dL and 9.2 g/dL; for S. paratyphi A, 12.0 g/dL and 11.8 g/dL; and for S. paratyphi B, 12.8 g/dL and 11.6 g/dL. According to the ANOVA test, there is a significant difference in the average hemoglobin levels among patients infected with S. typhi compared to those with S. paratyphi based on these antibody titers (< 0,001)
Differences in Random Blood Glucose Levels on Acceptors of the 1-Month Injection Contraceptive Program and the 3-Month Injection Contraceptive Program in the Working Area of the Masbagik Community Health Center Maruni Wiwin Diarti; Faiza Waziran Mulyadi; Iswari Pauzi; Urip Urip
Jurnal Analis Medika Biosains (JAMBS) Vol. 13 No. 01 (2026): JURNAL ANALIS MEDIKA BIOSAINS (JAMBS)
Publisher : Poltekkes Kemenkes Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Glucose is one of the products of carbohydrate metabolism in the body that functions as the main source of energy for the body, controlled by insulin. This increase in blood sugar is caused by the inefficient work of insulin, which is caused by the presence of injectable contraceptives. The progesterone hormone contained in injectable contraceptives has anti-insulin properties that cause cells to become less sensitive. Reduced insulin sensitivity can lead to insulin resistance in the body, which can affect glucose metabolism and result in elevated blood sugar levels. The objective of this study is to determine the difference in blood glucose levels among participants in the 1-month injection contraceptive program and the 3-month injection contraceptive program in the Masbagik Health Center service area. The sample in this study consisted of participants in the 1-month and 3-month injection contraceptive programs, with a total of 26 respondents (13 for each group). The data collected were glucose levels measured using the POCT (point-of-care testing) method. The data were analyzed using the Mann-Whitney statistical test. The results showed that the mean glucose level in 1-month contraceptive injection program participants was 108.8 mg/dL, while in 3-month program participants it was 142.9 mg/dL. The Mann-Whitney test results showed no significant difference between the blood glucose levels of 1-month contraceptive injection users and 3-month contraceptive injection users, with a value of 0.068 (p > 0.05). The conclusion of this study is that there is no significant difference in blood glucose levels between 1-month and 3-month contraceptive injection users. However, mathematically, there is an increase in the average values.
The Effectiveness of Nutrition Education and Utilization of Local Food Tokens in Reducing the Risk of CED and Anemia in Pregnant Women in Central Lombok Iswari Pauzi; Ni Putu Karunia Ekayani; Yudha Anggit Jiwantoro
Hydrogen: Jurnal Kependidikan Kimia Vol. 13 No. 6 (2025): December 2025
Publisher : Universitas Pendidikan Mandalika

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/hjkk.v13i6.18779

Abstract

This study aimed to evaluate whether nutrition education combined with the use of a local food product, TOKEN (Tongkol–Kentang/Tuna-Potato), could improve maternal nutritional indicators and reduce the risk of chronic energy deficiency (CED) and anemia among pregnant women in Jelantik Village, Central Lombok, Indonesia. A quasi-experimental one-group pretest–posttest design was conducted under the supervision of the local community health center, from April to September. Fifteen pregnant women were recruited through consecutive sampling based on eligibility criteria (willingness to participate, no severe chronic disease affecting dietary intake, and ability to attend sessions). The intervention consisted of (1) nutrition education on CED and anemia prevention, and (2) hands-on training to prepare TOKEN nuggets with standardized hygienic procedures, followed by light mentoring to encourage regular consumption and home practice. Outcomes were measured at baseline and post-intervention, including nutrition knowledge (structured questionnaire), mid-upper arm circumference (MUAC/LILA) (standard MUAC tape), and hemoglobin (Hb) levels (point-of-care testing). Pre–post changes were analyzed using paired t-test or Wilcoxon signed-rank test (p < 0.05). Results showed significant improvements in nutrition knowledge, MUAC (+0.61 cm, p < 0.001), and Hb (+0.92 g/dL, p < 0.001), with fewer women at risk of CED and anemia. Participants also improved TOKEN processing skills, supporting the feasibility of using local food. This approach may be a feasible community-based strategy to reduce CED and anemia risk, though larger studies with control groups are needed.
Analisis Pengaruh Variasi Waktu Inkubasi Sampel Terhadap Tingkat Presisi Dan Akurasi Pada Quality Control (QC) Pemeriksaan Cholesterol : Analysis of the Effect of Variations in Sample Incubation Time on Precision and Accuracy Levels in Quality Control (QC) of Cholesterol Testing Yunita Wardani; Urip Urip; Yunan Jiwintarum; Iswari Pauzi
Jurnal Teknologi Laboratorium Medik Borneo Vol. 5 No. 2 (2025): Jurnal Teknologi Laboratorium Medik Borneo
Publisher : Institut Teknologi Kesehatan dan Sains Wiyata Husada Samarinda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35728/jutelmo.v5i2.2041

Abstract

Pemeriksaan cholesterol metode fotometri memerlukan waktu inkubasi yang konsisten untuk menjamin presisi dan akurasi hasil.Tujuan penelitian ini Mengetahui pengaruh variasi waktu inkubasi sampel terhadap Tingkat presisi dan akurasi pada quality control (QC) hasil pemeriksaan cholesterol menggunakan metode fotometri.Penelitian ini merupakan penelitian kuantitatif dengan pendekatan eksperimental dimana populasi dan sampel penelitian ini adalah serum darah responden untuk pemeriksaan cholesterol. Penelitian ini dilakukan dengan mengukur kadar cholesterol variasi waktu inkubasi yang di modifikasi menjadi empat perlakuan yaitu, satu variasi waktu inkubasi (5 menit),variasi waktu inkubasi (10 menit), variasi waktu inkubasi (15 menit) dan variasi waktu inkubasi (20 menit). Data dianalisis untuk presisi dan akurasi, serta diuji statistik menggunakan One-Way ANOVA.Hasil pemeriksaan didapatkan Variasi waktu inkubasi pada kelompok perlakuan (5 menit) menunjukkan KV 3,30% dan recovery 98,78% hasil presisi dan akurasi, kelompok perlakuan (10 menit) menunjukkan KV 2,87% dan recovery 99,86% hasil presisi dan akurasi, kelompok perlakuan (15 menit) menunjukkan KV 2,56% dan recovery 100,20% hasil presisi dan akurasi, dan kelompok perlakuan (20 menit) menunjukkan 2,92% dan recovery 101,36% hasil presisi dan akurasi. Analisis statistik dengan uji One-way ANOVA didapatkan hasil (p) .538 (P> 0,05) yang menunjukkan tidak ada pengaruh pada quality control pemeriksaan cholesterol metode fotometri.Kesimpulan yang didapat Presisi dan Akurasi dari pengaruh waktu inkubasi (5 menit),(10 menit),(15 menit),(20 menit),adalah bagus.
Antioxidant Active Substances and Influence on Lipid Profile in White Rat Animal Experiments (Rattus norvegicus) Wistar from Kawista Fruit Extract (Limonia acidissima) Ida Bagus Rai Wiadnya; Iswari Pauzi
Lambda: Jurnal Ilmiah Pendidikan MIPA dan Aplikasinya Vol. 6 No. 2 (2026): Lambda
Publisher : Lembaga Bale Literasi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58218/lambda.v6i2.4262

Abstract

Background: Kawista fruit (Limonia acidissima) from Bima Regency, West Nusa Tenggara, is empirically known for its antioxidant, tonic, and digestive properties. Its chemical components, including terpenoids, polyphenols, and flavonoids, are expected to reduce lipid profile levels. Purpose: This study aimed to identify active compounds in kawista fruit extract and evaluate its effects on lipid profile (cholesterol, triglycerides) and fasting blood glucose in white rats (Rattus norvegicus) with NAFLD-induced liver damage. Methods: An experimental approach was used. Kawista fruit extract was prepared by maceration with 70% ethanol. Rats were induced with a high-lipid diet and PTU to trigger hypothyroidism. Parameters measured included body weight, total cholesterol, triglycerides, and fasting blood glucose before and after four weeks of treatment at three dose levels. Results: Phytochemical analysis confirmed the presence of terpenoids, polyphenols, and flavonoids, but no alkaloids or saponins. Kawista extract showed a significant effect on triglyceride levels (p=0.002), while effects on cholesterol (p=0.651) and fasting blood glucose (p=0.656) were not significant. Mann-Whitney post-hoc analysis showed significant differences between all groups except between the positive control and dose 1 (p=0.885). Conclusion: Kawista fruit extract has significant potential in reducing triglyceride levels in rats with NAFLD-induced hyperlipidemia, supporting its use as a natural antioxidant and lipid-lowering agent
Co-Authors A.A Sukarso Agus Muliadi Agus Muliadi Aliefmam Hakim Anam, Haerul Anaz, Haerul Aprilla, Annisa Suci Ari Khusuma Aris Doyan Aris Doyan Asrorul Makmur Azizi Ayu Rosita Bachtiar Ardiansyah Bachtiar Ardiansyah Baiq Eliya Yusrina Eliya Dektra, I Made Putra Pramaditya Dera Suci Elmaria Dewi, Lale Budi Kusuma Dewi, Ni Made Uci Pramesthy Dyah Astining Maya Erlin Yustin Tatontos Erna Kristinawati Ersandhi Resnhaleksmana Ershandi Resnhaleksmana Faiza Waziran Mulyadi Farhataini, Annisa Faylori, Adelia Yusnita Fihiruddin, Fihiruddin Fitriyani Fitriyani Fitriyani Fitriyani Gito Hadiprayitno Gito Hadiprayitno Hadi, Aprilia Khairunnisa Hakim, Aliefmam Hamidi Hamidi Haryanti, Alya Helenia Ananda Feriska Felanis I Gusti Ayu Nyoman Danuyanti I Ketut Swirya Jaya I Ketut Swiryajaya I Komang Agusjaya Mataram, I Komang Agusjaya IGAN Danuyanti Intan Mustika Nila Jiwantarum, Yunan Joni Rokhmat Joni Rokhmat Laelin Hijriyani Lalu Srigede, Lalu Mahayani, I Gusti Ayu Putu Sachita Maruni wiwin Danuarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maruni Wiwin Diarti Maya, Dyah Astining Maya, Kadek Melyana Nurul Widiawati Miftahul Aini, Miftahul Mira Pramesty Cahyaningtyas Muh. Zaini Hasanul Muttaqin Muhammad Sarjan Muhammad Sarjan Muhammad Yamin Muhammad Yamin MULIA RASYIDI Naning Fitri Yuliatrik Ni Putu Agustini Ni Putu Karunia Ekayani Nila, Intan Mustika Nurul Inayati Nurul Inayati Pusaka, Semerdanta Rahmani, Putri Ziddanur RAI WIADNYA, IDA BAGUS Resnhaleksmana, Ersandhi Rindu Rahmatiah Rindu Rahmatiah Rohmi Sahputri, Maulidia Rohmiati Septiawan, Dandi Shohifatul Wahyuni Siti Malika Amini Siti Rif’ah Sabariah Siti Zaetun Siti Zaetun, Siti Sitiana, Nining St. Halimatussya’diah Suda Adnyana Yoga, I Gede Sudarmi Sudarmi Sudirman Sudirman Sudirman Sudirman Sukarso, A.A Tasya, Rabaika Monica Thomas Tandi Manu Urip Urip Urip Urip Urip Urip Urip, Urip Wahyuni, Shohifatul Yudha Anggit Yudha Anggit Jiwantoro Yuli Laraeni Yunan Jiwintarum Yunan Jiwintarum Yunan Jiwintarum Yunita Wardani Yusran Khery Yusran Khery Zaena Safitri, Trysia