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Rahmawati, Siti Irma
Universitas Djuanda
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Analisis Manajemen Risiko Pada UMKM “Mie Ayam Mas Adi” Bandung Arrachman, Hajar Chair; Karimah, Nur Rafidah; Rahmawati, Siti
Jurnal Serambi Ekonomi dan Bisnis Vol 8, No 1 (2024): September 2024 -Februari 2025
Publisher : Universitas Serambi Mekkah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32672/jseb.v8i1.8692

Abstract

Businesses that are currently developing are small businesses, where the business does not require a lot of capital, and the process of setting it up is easy. Small businesses are business activities that have small initial capital, small assets, and a small number of workers. It can be said that a small business is an individual business or legal entity that carries out simple economic activities with the aim of making a profit within certain limits. Traders are one of the micro and medium enterprises whose implementation requires relatively small capital and usually uses their own capital or loans.
Analisis Manajemen Risiko pada UMKM Apa Ya Food Karimah, Nur Rafidah; Arrahman, Hajar Chair; Rahmawati, Siti
Jurnal Serambi Ekonomi dan Bisnis Vol 8, No 1 (2024): September 2024 -Februari 2025
Publisher : Universitas Serambi Mekkah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32672/jseb.v8i1.8693

Abstract

Pempek, a traditional delicacy from Palembang, Indonesia, is made from finely ground fish mixed with tapioca flour and shaped into various forms such as pempek kapal selam and pempek lenjer. Its preparation involves mixing ingredients, shaping, and boiling, often served with cuko, a sweet, sour, and spicy sauce that enhances its flavor. Pempek is not only delicious but also nutritious, high in protein from fish. Dimsum, originating from China, has been adapted into diverse variations in Indonesia. Typically consisting of a dough filled with meat, vegetables, or other ingredients, dimsum is either steamed or fried. Known for its variety, it is often enjoyed as a snack or side dish during gatherings. Meanwhile, snacks in Indonesia encompass a wide range of small bites that can be enjoyed anytime, including chips, traditional snacks like risoles and pastel, and moist cakes. These snacks feature a variety of flavors, from sweet to savory, and frequently use local ingredients such as cassava, glutinous rice, and coconut. All three food categories pempek, dimsum, and snacks are not only popular among locals but are also gaining recognition internationally. Through innovations in recipes and presentation, they continue to evolve to suit modern consumer tastes.
Roselle and Red Ginger: A Potential Combination of Medicinal Plants for Hypertension Therapy Yunas, Ranum Wanudya; Rahmawati, Siti Irma; Saputri, Fadlina Chany; Bayu, Asep; Chianese, Giuseppina; Putra, Masteria Yunovilsa
Pharmaceutical Sciences and Research
Publisher : UI Scholars Hub

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Hypertension is a prevalent cardiovascular condition that significantly increases the risk of heart disease and stroke. Effective management is essential to prevent severe complications. Roselle (Hibiscus sabdariffa L.) and red ginger (Zingiber officinale var. rubrum) are two medicinal plants known for their antihypertensive properties. Roselle contains bioactive compounds such as anthocyanins that exhibit vasodilatory and angiotensin-converting enzyme (ACE) inhibition, while red ginger is rich in gingerols and shogaols, which possess anti-inflammatory and vasodilatory properties. The complementary mechanisms of action of these two plants, including ACE inhibition, antioxidant activity, and modulation of vascular tone, result in a more pronounced antihypertensive effect when used together. By targeting multiple pathways, the combination allows for more effective blood pressure control, which could lead to improved patient outcomes. The purpose of this study is to provide a detailed review of the evidence supporting the use of roselle and red ginger in combination as a potential therapeutic approach for hypertension. This review aims to identify gaps in the existing research and suggest directions for future studies. Understanding the synergistic effects of these plants can help in developing more effective herbal therapies that leverage their combined benefits. Further research is needed to confirm these findings through more in-depth preclinical and clinical studies. Investigations should focus on optimizing dosages, understanding long-term safety, and establishing standardized protocols for combination therapy. This review serves as a foundation for future research and encourages the integration of traditional herbal medicine into modern hypertensive management strategies, promoting a holistic approach to cardiovascular health.
Deteksi Cepat Formalin Menggunakan Zat Warna Kelopak Bunga Rosella ((Hibiscus Sabdariffa L.) Pada Berbagai Produk Pangan Basah Tirtawati, Desi; Mardiah; Rahmawati, Siti Irma
JURNAL AGROINDUSTRI HALAL Vol. 11 No. 1 (2025): Jurnal Agroindustri Halal
Publisher : Universitas Djuanda

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30997/jah.v11i1.15681

Abstract

One of the dangerous substances still used in food goods as a preservative is formalin. The public finds it challenging to identify food products that contain formalin because formalin testing has so far been done in labs using chemical reagents. Formalin may be identified using anthocyanin dyes, according to the findings of multiple studies. Anthocyanin dyes are reported to be present in rosella flowers. Finding out if rosella flower extract can be utilized to detect formalin in different wet food products was the aim of this investigation. Using water and ethanol solvents, fresh rosella flower petal extract and dried rosella were prepared in different ratios of 1: 4, 1: 6, and 1: 8. The resulting food product samples were then tested on white tofu, lontong, and yellow noodles. The color changes that transpired in samples that were provided liquid rosella flower petal extract and the paper kit test were used to conduct qualitative observations. Formalin identification was analyzed by comparing the qualitative and quantitative findings of laboratory tests. The study's findings demonstrated that food samples containing formalin with a pH of greater than 8 underwent a color shift. In the paper kit test of fresh Rosella flower petal extract, the red color turned yellow and went from red to greenish blue. While the results of observations of color changes using dried rosella flower petal extract were more difficult to detect because the color was too thick. The fresh rosella flower petals ethanol extract with a 1:8 ratio produced the best results.
Aktivitas Antioksidan Kapang Endofit asal Rumput Laut Caulerpa lentilifera Septiana, Eris; Hardhiyuna, Mutia; Untari, Febriana; Bustanussalam, Bustanussalam; Rahmawati, Siti Irma
Jurnal Pascapanen dan Bioteknologi Kelautan dan Perikanan Vol 20, No 1 (2025): Juni 2025
Publisher : Politeknik - Ahli Usaha Perikanan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15578/jpbkp.v20i1.1040

Abstract

Aktivitas antioksidan dari ekstrak rumput laut telah banyak dilaporkan. Namun, belum banyak peneliti yang melaporkan aktivitas antioksidan dari kapang endofit asal rumput laut. Penelitian ini bertujuan untuk mengisolasi kapang endofit dari rumput laut C. lentilifera, mengevaluasi aktivitas antioksidan, serta profil senyawa kimia ekstrak terpilih. Isolasi kapang endofit dilakukan dengan metode sterilisasi permukaan dan ditanam pada media Potato Dextrose Agar (PDA). Uji antioksidan menggunakan metode 2,2-Diphenyl-1-picrylhydrazyl (DPPH), 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS), dan ferric reducing antioxidant power (FRAP). Penentuan kadar fenolik dan flavonoid total masing-masing berdasarkan pada reaksi reagen Follin-Ciocalteu dan aluminium klorida. Ekstrak dengan aktivitas antioksidan terbaik dilakukan profiling senyawa kimianya menggunakan Kromatografi Gas-Spektroskopi Massa (KG-SM). Hasil isolasi didapatkan lima isolat kapang endofit yaitu Cl.Tka.S1, Cl.Tka.S2, Cl.Tka.S3, Cl.Tka.R1, dan Cl.Tka.R2. Ekstrak kapang endofit Cl.Tka.S3 memiliki aktivitas tertinggi dengan nilai IC50 sebesar 17,65 ± 1,88 dan 37,07 ± 2,16 mg/L pada metode ABTS dan DPPH,serta uji FRAP dengan kadar setara Fe(II) sebesar 1654,15 ± 32,95 µmol/mg ekstrak. Kadar fenolik total tertinggi didapatkan dari ekstrak kapang endofit Cl.Tka.S1 sebesar 75,05 ± 8,46 mg setara asam galat/g ekstrak. Kadar flavonoid total tertinggi didapatkan dari ekstrak kapang endofit Cl.Tka.S3 sebesar 38,50 ± 1,55 mg setara kuersetin/g ekstrak. Profiling senyawa kimia menunjukkan ekstrak isolat Cl.Tka.3 sebagai isolat terbaik mengandung senyawa antioksidan berupa senyawa golongan fenolik, asam lemak, alkana, dan alkohol. KATA KUNCI: ABSTRACTThe antioxidant activity of seaweed extracts has been widely reported. However, reports on the antioxidant activity of endophytic fungi derived from seaweed are still limited. This study aims to isolate endophytic fungi from C. lentilifera, determine antioxidant activity and chemical profiles of selected extracts. Endophytic fungi were isolated by the surface sterilization method and planted on Potato Dextrose Agar (PDA) media. Antioxidant test using 2,2-Diphenyl-1-picrylhydrazyl (DPPH), 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid (ABTS), dan ferric reducing antioxidant power (FRAP) methods. Total phenolic and flavonoid content was based on the reaction of Follin-Ciocalteu reagent and aluminium chloride, respectively. Extracts with the best antioxidant activity were profiled for their chemical compounds using Gas Chromatography-Mass Spectroscopy (GC-MS). The isolation results obtained five isolates of endophytic fungi, namely Cl.Tka.S1, Cl.Tka.S2, Cl.Tka.S3, Cl.Tka.R1, and Cl.Tka.R2. Cl.Tka.S3 extract had the highest activities with an IC50 value of 17.65 ± 1.88 and 37.07 ± 2.16 mg/L on the ABTS and DPPH methods, as well as FRAP test values with Fe(II) equivalent levels of 1654.15 ± 32.95 µmol/mg extract. Cl.Tka.S1 extract has the highest total phenolic content of 75.05 ± 8.46 mg gallic acid equivalent/g extract. Cl.Tka.S3 extract has the highest total flavonoid content of 38.50 ± 1.55 mg quercetin equivalent/g extract. Profiling of chemical compounds showed that the Cl.Tka.S3, as the best extract, contained antioxidant compounds such as phenolic compounds, fatty acids, alkane, and alcohol.
Anti-inflammatory Activity of Glucomannan Resulting from β-mannanase Enzyme Hydrolysis in RAW 264.7 Cells Nuraini, Nuraini; Effionora Anwar; Dian Ratih Laksmitawati; Hendig Winarno; Siti Irma Rahmawati
Journal of Natural Product for Degenerative Diseases Vol. 2 No. 2 (2025): JNPDD March
Publisher : Faculty of Pharmacy Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58511/jnpdd.v2i2.7797

Abstract

Glucomannan is a polysaccharide of the hemicellulose type, composed of glucose and mannose chains. It has the ability to form solutions that expand and thicken. The bioactivity of carbohydrates is influenced by the length of their saccharide chains. Hydrolysis can alter the structural dimensions of polysaccharides, including molecular weight, type, number, and position of substituent groups, which in turn impacts their biological activity. Various methods can modify carbohydrate structures to enhance their value, with degradation being one such method. Enzymatic degradation is particularly advantageous due to its high specificity, efficiency, and minimal side effects. Numerous studies have identified glucomannan as having immunomodulatory effects on macrophage cells. When stimulated with lipopolysaccharides, macrophages release various cytokines and inflammatory mediators, such as TNF-α, iNOS, and NO. This study explored the potential anti-inflammatory effects of glucomannan (GM) and its enzymatically hydrolyzed form (Enz-GM) on RAW 264.7 cells. The research involved degrading glucomannan using the β-mannanase enzyme, followed by in vitro testing of the degradation product (Enz-GM) for anti-inflammatory activity. This was achieved using an ELISA kit to measure the expression of IL-6, TNF-α, and iNOS. The results showed that Enz-GM at pH 9 (Mw 1.24 kDa) significantly reduced the pro-inflammatory cytokines IL-6 and iNOS (p ≤ 0.05) compared to GM, while TNF-α expression did not show a significant difference between Enz-GM and GM.
Co-Authors . Anidah . Aslan . Kholik A.A. Ketut Agung Cahyawan W Abdul Latif Abdullah, Muhamad Al Faruq Afifah Rosyidah Afifah, Diana N. Ahmad Syauqy Aji Jumiono Alicia Cherie Chandra Andreayani Attamimi Anggun Hari Kusumawati Anis H. Mahsunah Anisyah, Yuni Nur Anjani, Gemala Annis Catur Adi Annisa Rizky Maulidiana Apon Zaenal Mustopa Apon Zaenal Mustopa Ardiana, Hana Ai Ariestyani, Imelda Armaiki Yusmur Arrachman, Hajar Chair Arrahman, Hajar Chair Aulanni'am, Aulanni'am Aulanni’am Aulanni’am Bayu, Asep Bugi Ratno Budiarto Bustanussalam Bustanussalam Bustanussalam Bustanussalam Bustanussalam Bustanussalam Bustanussalam Bustanussalam Bustanussalam, Bustanussalam Chianese, Giuseppina Choirun Nisa Riski Damayanti, Aprilia F. Danil Eka Fahrudin Darmawati Dalle Dharmawan, Devi Diah Anggraini Wulandari Dian Ratih Laksmitawati Diana Nur Afifah, Diana Nur Donald, Eriklex Dwi Aryanti Effionora Anwar Ekkel Lintang Aisyiyah Elke Stephanie Ella Saparianti Elok Zubaidah Endang Mahati Endang Saepudin Eris Septiana Eris Septiana Eris Septiana Eris Septiana Eris Septiana ERIS SEPTIANA Eris Septiana Eris Septiana Fadhilah, Syifa Fadlina Chany Saputri Fahad Fauzan Al Munawar Fariha Willisiani Fauzia Izzati Fauzia Nurul izzati Fauzia Nurul Izzati Fauzia Nurul Izzati Fauzia Nurul Izzati Fauzia Nurul Izzati Fauzia Nurul Izzati Fauzia Nurul Izzati Fauzia Nurul Izzati Fauzy Rachman Fauzy Rachman Fauzy Rachman Fauzy Rachman Fauzy Rachman Fauzy Rahman Febriandy, Agustio Febriansyah, Ilham Ferdina Tri Laksmita Fikayuniar, Lia Fitri Amalia Fitri Nur Hikmah Fitrilia, Tiana Ghina Putri Dyanti Ghina Putri Dyanti Gita Syahputra Hadistio, Alfin Hairida Hendig Winarno Heni Pujiastuti Husaini Maulana Ishmah Hanifah Joko Hermanianto Karimah, Nur Rafidah Kharyani, R. Aldini Kristanti Indah Purwani Leny Heliawati Leo, Leviena Merlynike Lestari Makmuriana Lola Ayu Istifani Lutfi Alhazami M. Rizky Eka Putra Vi Safrillah MADE ASTAWAN Mardiah Mardiah Marhamah, Irma Siti Martha Sari Martha Sari Masteria Yunovilsa Putra Masteria Yunovilsa Putra Melody Angel Masadi Muhammad Ilman Muhammad Surya Madani Muhibuddin, Anton Mutia Hardhiyuna, Mutia Nada Nisrina Nastiti Wijayanti Nelwan, Sindy Cornelia NFN Bustanussalam NFN Yadi Noli Novidahlia Nopita Aliani Nunik Gustini Nur Afifah Nur Rohmah Nuraini Nuraini Nurcahali, Fani Nurman Maulana Ikhsan Partomuan Simanjuntak Partomuan Simanjuntak Partomuan Simanjuntak Partomuan Simanjuntak Partomuan Simanjuntak Partomuan Simanjuntak Permatahati, Ghina Sri Puspo Edi Giriwono Putra, Masteria Yunovilsa Qisthina, Dalilah Rachmat Sahputra Rahma Micho Widyanto Ramadhaniyati, Ramadhaniyati Ratna Chrismiari Purwestri Ratna Ediati Rika Damayanti Rikno Harmoko Rikno Harmoko Rikno Harmoko Rosy Hutami Saiful Bachri Salcia Inka Nelanda Saniyya, Ashila Nasyadhiya Setyawati, Amalia Rani Siregar, Maruli Siti Aminah Siti Nurhalimah Siti Nurjanah Slamet Budjianto SOETJIPTO . Soetjipto Soetjipto St Maisarah Sukarno Sukarno Sunaryo, Endang S. Suprayatmi, Mira Suprayatmi, Mira Suryandari Suryandari Syamsiah Syamsiah Tirtawati, Desi Titi Rohmayanti Tutik Wresdiyati Udijanto Tedjosasongko Untari, Febriana Utami, Nur' Widjajanti, Widjajanti Wien Kusharyoto Wyna Nabila Yadi Yadi Yatri Hapsari Yatri Hapsari Yatri Hapsari Yatri Hapsari Yatri Hapsari Yohana P. Br Sianturi Yuliana, Resti Yuliana, Resti Yumi Sartika Yunas, Ranum Wanudya