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All Journal Jurnal Ilmiah Farmasi JURNAL GIZI INDONESIA Syntax Literate: Jurnal Ilmiah Indonesia Farmasains : Jurnal Ilmiah Ilmu Kefarmasian Window of Health : Jurnal Kesehatan JURNAL FARMASIMED (JFM) Pharma Xplore : Jurnal Sains dan Ilmu Farmasi Jurnal Riset Kefarmasian Indonesia Science Midwifery Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Jurnal Farmasi Jurnal Farmasi dan Sains Indonesia (JFSI) JOURNAL LA MEDIHEALTICO Indonesian Journal of Multidisciplinary Science Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Farmasi Indonesia Medical Sains : Jurnal Ilmiah Kefarmasian Praeparandi: Jurnal Farmasi dan Sains

Siti Pandanwangi TW

Pharmacy Study Program, STF YPIB Cirebon, West Java, Indonesia

Author-ID : 1029212

Humanities Biochemistry, Genetics & Molecular Biology Chemistry Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Mathematics Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

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PENGARUH EKSTRAK DAUN KEMBANG BULAN (Tithonia diversifolia A.Gray) TERHADAP KADAR GLUKOSA DARAH TIKUS PUTIH WISTAR YANG DIINDUKSI OLEH ALOXAN Pradiningsih, Anna; Pandanwangi Tw, Siti; Aribowo, Aribowo
Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan) Vol. 1 No. 2 (2017): Journal of Holistic and Health Sciences (Jurnal Ilmu Holistik dan Kesehatan)
Publisher : Sekolah Tinggi Ilmu Kesehatan Holistik

Background: Diabetes mellitus becomes a major health problem because its complications are short and long term. Plants used for the treatment of diabetes, one of which is Daun Kembang Bulan (Tithonia diversifolia A.Gray). Daun Kembang Bulan (Tithonia diversifolia A.Gray) is used as an anti-diabetic with the active substance of sesquiterpene compound, 1?-hydroxydiversifolin-3-O-methyl ether and 1?-hydroxytirotundine-3-O-methyl ether, isolated from the aerial part-all parts of the plant except root of Kembang Bulan (Tithonia diversifolia A.Gray) Objective: To find out whether the Daun Kembang Bulan (Tithonia diversifolia A.Gray) had an effect on aloxan-induced glucose levels of rats, knowing which doses were more effective had a decreasing effect on rat glucose and on the stability of the leaf-bloom formulation of Daun Kembang Bulan (Tithonia diversifolia A.Gray) Method: The research method used is experimental method. The extract suspension was prepared with three doses, 200 mg/kgBB , 300 mg/kgBB, dan 400 mg/kgBB performed on 15 male rats induced aloxan. Result: Based on the result of measurement of the decrease of blood glucose level on male white rats after 21 days treatment can be seen that the suspension of Daun Kembang Bulan (Tithonia diversifolia A.Gray) extract at dose 200 mg/kgBB, 300 mg/kgBB, and 400 mg/kgBB obtained percentage decrease equal to 44%, 62.3% and 63.2%. On the Positive Control of Acarbose suspended with a dose of 9 mg/kgBB obtained percentage decrease of 57%. On Negative Control the 1% CMC suspension yields an increase percentage of 15.7%. The result of data analysis with T test test stated that there was no significant difference between the three doses with positive control. Conclusion: The effective dose is the dose with the lowest percentage of 200 mg/kgBB. The suspension stability of Daun Kembang Bulan (Tithonia diversifolia A.Gray) extract at doses of 200mg/kgBB, 300 mg/kgBB dan 400 mg/kgBB, positive control and negative control is relatively stable at temperatures of 0 0C, 25 0C and 50 0C.

A Systematic Review of Knowledge and Perception Regarding Generic Medicines Among Indonesians Pandanwangi TW, Siti; Agustina, Diana; Karsidin, Bambang
Journal La Medihealtico Vol. 5 No. 2 (2024): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v5i2.1187

Generic medicines are a type of medicine with an official name that has been assigned to the efficacious substance it contains. Generic medicines have the same effectiveness as patented medicines. Many people think that generic medicines are of low quality, so they prefer branded generic medicines or patented medicines. This systematic review aims to report the results of a search for previously reviewed studies that focus on the level of public knowledge and perception of generic medicines. The research method used is a literature study method using journal data from the last 10 years. Journal collection was carried out by searching online journal databases indexed in Google Scholar, and PubMed using Mesh (Medical Subject Headings) with a focus on the keywords "knowledge", "perception", and "generic medicines". The results of this research are that the level of Indonesian people's knowledge of generic medicines is quite good but not evenly distributed, especially among groups of people who have a strong belief that cheap medicines are of lower quality. Acceptance of generic medicines tends to be higher in communities with higher levels of education. Communities with low socio-economic conditions generally have a low level of education so they tend to have greater distrust of generic medicines. This research concludes that it is important to provide information about generic medicines aggressively and continuously to the public to increase public trust in generic medicines. In addition, prescribing generic medicines by physicians is the main thing to eliminate public distrust about generic medicines.

The Relationship Between Nutritional Status And Insulin-Like Growth Factor-1 Levels In Stunted Children In Cirebon Regency Siti Pandanwangi; Akrom; Nurkhasanah; Zuniarto, Ahmad Azrul; Hidayati, Titiek; Tsai, Mei Ling
Window of Health : Jurnal Kesehatan Vol 7 No 3 (July 2024)
Publisher : Fakultas Kesehatan Masyarakat Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/woh.v7i2.1299

Insulin-like Growth Factor-1 (IGF-1) is a growth hormone mediator that acts as a growth-promoting factor in the growth process and is also an indicator of the adaptive immune system. Children who experience stunting will experience obstacles to growth and cognitive and motor development, affecting their productivity as adults. This research aims to determine IGF-1 levels and their relationship with stunted children's nutritional status. The research method used was observational, with a cross-sectional research design. The population of stunted children in the Tegalwangi locus area, Cirebon Regency, a sample of children aged 24-60 months who met the inclusion criteria of not being disabled and not being sick, was 50 children. The research began with parents filling in informed consent. Continue to fill in data on date of birth, measure height and weight, take @1ml of the child's blood, and analyze IGF-1 using the ELISA method. The research results were that the average IGF-1 level for men was 16,812 ± 5,164 ng/ml and for women 13,810 ± 5,111 ng/ml. Average IGF-1 levels aged 24-36 months were 14,777 ± 4,742 ng/ml, 36–48 months 17,050 ± 4,280 ng/ml, and 48–60 months 15,214 ± 6,248 ng/ml. Data analysis using the Pearson correlation test obtained a value of p=0.871 based on age, p=0.047 based on gender, p=0.643 based on Height for age, and p=0.245 based on Weight for age (95% CI). The conclusion is that there is a relationship between the age of a stunted child and IGF-1 levels, and there is no relationship with nutritional status. All stunted children have IGF-1 values below the standard value for normal children based on the literature, namely ≥ 28.54 ng/ml.

THE COMPLIANCE AND EFFECTIVENESS OF TUBERCULOSIS DRUG USE AT THE TALUN HEALTH CENTER IN CIREBON Regar, Dhea Novakinanda; Zuniarto, Ahmad Azrul; Pandanwangi TW, Siti; Widianingsih, Nining
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 9 No 4 (2024)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v9i4.1334

Tuberculosis (TB) is an infectious disease caused by Mycobacterium tuberculosis (Mtb). This disease affects the lung organs and may also affect organs outside the lungs. This study aimed to determine the level of compliance and effectiveness of TB drugs, the relationship between compliance and effectiveness in using TB drugs, and the relationship between compliance and effectiveness based on socio-demographic data of the community. The research method used was descriptive observational, with retrospective data collection based on TB patient treatment cards. Compliance data were collected by completing the MMAS questionnaire, and effectiveness data were collected by recording sputum examination results using the SITB (Tuberculosis Information System) software. The sample comprised the total population according to these criteria. The technique used for sampling was total sampling, namely the total number of TB patients at Talun Health Center, Cirebon Regency, from November 2023 to April 2024, a total of 40 patients. Data analysis using the Spearman test consisted of compliance analysis, effectiveness analysis, the relationship between compliance and effectiveness, and the relationship between compliance and effectiveness based on socio-demographic data of the population. The results of the study showed that the level of compliance with TB drug use was 7.9 (medium level of compliance), and the effectiveness of TB drug use was 100%. There is a relationship between compliance and the effectiveness of TB drug use, but there is no relationship based on the socio-demographic data of the population. Keywords: Compliance, Effectiveness, TB Drugs

Effectiveness of Topical Tranexamic Acid in the Treatment of Melasma Pandanwangi, Siti; Setriyadi, Dedy; Dzulhijjah, Hawa
Journal La Medihealtico Vol. 6 No. 2 (2025): Journal La Medihealtico
Publisher : Newinera Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37899/journallamedihealtico.v6i2.1923

Melasma is a chronic skin hyperpigmentation condition that often occurs in women of reproductive age, especially in areas exposed to sunlight. One of the therapeutic agents that has attracted attention is tranexamic acid (TXA), which was originally used as an antifibrinolytic agent, but is now known to have an effective mechanism of action in reducing hyperpigmentation. TXA works through plasminogen inhibition, tyrosinase activity, and angiogenesis, as well as providing anti-inflammatory effects. This study uses the PRISMA systematic review method, involving the analysis of 30 relevant articles out of a total of 289 articles identified. The results showed that topical TXA in various formulations, such as creams, gels, or liposomal serums, provided a significant reduction in the Melasma Area and Severity Index (MASI) score. The combination of TXA with other modalities, such as microneedling, laser, and vitamin C, showed more effective results than monotherapy. Topical TXA is an effective and safe therapeutic agent for melasma, especially in the case of refractory or combination therapies. Further research is needed to evaluate the long-term effectiveness and innovation of new formulations in improving the penetration and efficacy of TXA.

Formulasi Lotion Sari Buah Mangga (Mangifera Indica L.) Sebagai Pelembab Kulit Karphiawati, Aldilla Shalsa; Zuniarto, Ahmad Azrul; Pandanwangi TW, Siti; Karsidin, Bambang; Nafi'ah, Rahma; Zakiah, Fitri; Dewi, Komala
Jurnal Farmasi & Sains Indonesia Vol 7 No 1 (2024)
Publisher : LPPM Sekolah Tinggi Ilmu Farmasi Nusaputera

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.52216/jfsi.vol7no1p28-34

Making mango juice lotion (Mangifera indica L.) using various concentration variations is expected to produce mango juice lotion (Mangifera indica L.) which meets the requirements for a good lotion and tests skin moisture against the mango juice lotion formula (Mangifera indica L.). This study aims to determine the best concentration of mango (Mangifera indica L.). In this study, mango juice was obtained by extortion, made in the form of lotion and tested for skin moisture using a Skin Analyzer. Data analysis in the form of SPPS (Statistical Product and Service Solution) tables. The results showed that the addition of the concentration of mango juice (Mangifera indica L.) had an effect on the resulting skin moisture. The selected formula of Mango juice lotion (Mangifera indica L.), namely formula 1 with a concentration of 5%, has a skin moisture value of 70,55%, and Mango fruit juice lotion (Mangifera indica L.).

Pengaruh Home Visit terhadap Kepuasan Konsumen Apotek Palasari Sumedang Zuniarto, Ahmad Azrul; Subagja, Subagja; Nurhasanah, Sarah; Sundari, Retno T; Pandanwangi, Siti
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 15 No 1 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Abstract: In the context of service of pharmaceutical at pharmacy, patients satisfaction is a pleasure feeling appearing in someone’s body after getting service taken directly. The analysis of customer’s satisfaction is based on five dimensions of service quality, which are among others responsiveness, reliability, assurance, empathy, and tangible. The purpose of the research was to find out the influence of home visit activity toward the customer’s satisfaction at Palasari pharmacy Sumedang and the satisfaction level of customer’s satisfaction before and after the home visit activity. This research was a quantitative one where the independent variable was home visit whereas the dependent variable was the customer’s satisfaction at Palasari pharmacy Sumedang. The technic of sample taking was total sampling. The samples used in the research were 34 respondents, they were the PRB patients from Palasari pharmacy at Ganeas district who never take the medicine regularly. The research instruments used in the research was questionnaire of customer’s satisfaction. The results of the study with a questionnaire on the level of consumer satisfaction at Palasari Sumedang Pharmacy before the home visit and after the home visit experienced an increase in percentage results from 75.4% to 81.5% and a simple linear regression test showed that there was an effect of home visits on satisfaction consumer Pharmacy Palasari Sumedang with a value sig. 0.000. Results study show that Home visits are influential to satisfaction consumer Pharmacy Palasari Sumedang with level satisfaction consumers 75.4 % increase to 81.5%.

Comparative analysis of macronutrient, vitamin, and mineral intake between stunted and non-stunted children in cirebon Pandanwangi, Siti; Akrom, Akrom; Nurkhasanah, Nurkhasanah; Zuniarto, Ahmad Azrul
Jurnal Gizi Indonesia (The Indonesian Journal of Nutrition) Vol 13, No 2 (2025): June
Publisher : Department of Nutrition Science, Faculty of Medicine, Universitas Diponegoro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/jgi.13.2.162-169

Background: The food consumed by children greatly affects how they will live in the future. The amount of nutrition that enters a child's body affects their health and intelligence. Macronutrients, vitamins and minerals are vital components in the body for the processes of growth and development, endurance, and other important functions. Low nutritional intake in children will cause them to experience growth failure, resulting in stunting.Objectives: This study was to compare the intake of macronutrients (protein, fat, and carbohydrate), vitamins (A, E, B1, B2, B6, C, folate), and minerals (sodium, potassium, magnesium, calcium, phosphorus, iron, and zinc) between stunted and non-stunted childrenMaterials and Methods: This study used a cross-sectional design. The population of the study was toddlers living in the Tegalwangi area, a sample of 100 children, ages 2 to 5, who were willing to sign a consent form as research subjects was split into 50 stunting and 50 non-stunting children. The time for the study began in January-May 2023. Data was collected using the 3x24 hour nutritional recall questionnaire method, followed by converting nutritional intake through the Nutrisurvey softwareResults: Nutritional intake for stunted children, shows that there are 12 intake criteria below the nutritional adequacy rate, while 5 intake criteria meet the standard. While for children who are not stunted, 12 criteria meet and 5 criteria do not meet the nutritional adequacy standard.Conclusion: Analysis of differences in the intake of the two groups found that there were no significant differences in the intake of macronutrients (carbohydrates), vitamins (E, B2) and minerals (sodium, potassium, calcium and phosphorum) with p>0.05, and significant differences in the intake of macronutrients (protein, fat). vitamins (A, B1, B6, C, folate), and minerals (magnesium, iron, zinc) with p<0.05.

ANALISIS TINGKAT PENGETAHUAN DAN PERSEPSI SWAMEDIKASI OBAT ANALGETIK PADA SISWA DI SMAN 3 CIREBON Nurrahma Berlian, Febia; Azrul Zuniarto, Ahmad; Pandanwangi, Siti; Rubihatlan, Encis; Minhatul Maula, Ajni; Farhan Alfawwaz, Azriel; Salafi, Akil; Sri Virgianti, Deby
Jurnal Farmasi (Journal of Pharmacy) Vol. 12 No. 1 (2023): Jurnal Farmasi (Journal of Pharmacy), April 2023
Publisher : Sekolah Tinggi Ilmu Kesehatan Nasional & Pengurus Cabang Ikatan Apoteker Indonesia (IAI) Sukoharjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.373013/qz9tq825

Self-medication is the selection and use of drugs by individuals or family members without doctor's instructions, to treat conditions that are recognized or self-diagnosed. Analgesics or what is often referred to as pain-blocking drugs without losing consciousness. This study aims to determine the level of students' knowledge about self-medication of analgesic drugs at SMAN 3 Cirebon, to determine students' perceptions of self-medication of analgesic drugs at SMAN 3 Cirebon, to determine the level of knowledge and perceptions of students towards self-medication of analgesic drugs based on student characteristics, and to determine the level of knowledge and students' perceptions of self-medication of analgesic drugs based on the indicators of the questions assessed. This research method is a quantitative research using a descriptive design. The sampling technique used purposive sampling technique. Data collection used an e-questionnaire (google form) which was given to 82 respondents who met the inclusion and exclusion criteria. The data analysis technique of this research uses descriptive analysis. The results of the research on the level of knowledge and students' perceptions about self-medication of analgesic drugs at SMAN 3 Cirebon found that the level of knowledge obtained an average value of 78.96% was included in the good category. Students' perceptions obtained an average score of 83.63% included in the very good category. Based on the characteristics of respondents who have good knowledge and very good perception, most are at the age of 16 years, female gender, parents work as private employees, pain experienced by respondents in the last 1 month, namely body/muscle pain, history of drug use, namely paracetamol and places get medicine namely Pharmacy. The level of students' knowledge about self-medication of analgesic drugs based on the indicators of questions that were assessed correctly, namely: 78.66% on the indicator of the level of safety and accuracy of drug use, 74.39% on the indicator of drug dosage, 93.9% on the indicator of drug use, 64, 63% on the indicator of how to use the drug 74.39% on the indicator of drug side effects, 89.02% on the indicator of how to store it, 97.56% on the indicator of drug expiry time, and 64.63% on the indicator of drug destruction.

Profil Penggunaan Obat Off-Label pada Pasien Pediatri Infeksi Saluran Pernapasan Akut di RSUD Majalengka Joharudin, Ade; Pandanwangi, Siti; Lestar, Puri
Syntax Literate Jurnal Ilmiah Indonesia
Publisher : Syntax Corporation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36418/syntax-literate.v9i11.54912

Infeksi Saluran Pernapasan Akut merupakan penyakit infeksi yang menyerang saluran pernapasan manusia dan paling banyak menyerang anak kecil (pediatri). Obat di luar label atau obat off-label didefinisikan sebagai obat yang penggunaannya diluar ketentuan mengenai dosis, cara pemberian, kontraindikasi dan indikasi. Tujuan dari penelitian ini yaitu untuk mengetahui presentase kejadian dari masing masing kategori penggunaan obat off label yang meliputi, off label dosis, off label rute pemberian, off label indikasi, dan off label kontraindikasi serta mengetahui jenis obat off label yang banyak digunakan dalam terapi pengobatan infeksi saluran pernapasan akut di RSUD Majalengka. Penelitian ini diambil menggunakan data rekam medis secra retrospektif pada Januari 2022-Desember 2022. Metode penelitian deskriptif non-eksperimental. Pengambilan data dilakukan menggunakan metode cross sectional secara retrospektif dengan melakukan telaah rekam medis pasien anak di RSUD Majalengka tahun 2022 dengan jumlah sampel yang diambil sebanyak 96 pasien anak ISPA. Hasil penelitian yang memenuhi kriteria terdapat 1 kategori yang termasuk kedalam off label dari 5 kategori yang diteliti, diantaranya ada sebanyak 27 kasus atau (15%) penggunaan obat off-label dosis. Tidak ditemukan kejadian pada kategori off-label rute pemberian, off-label usia, off-label indikasi dan off-label kontraindikasi. Dalam kasus penggunaan obat off label dosis terbanyak diantaranya yaitu Cefixime Dry Sirup sebanyak 12 item; Sedangkan Ambroxol Tablet; Ambroxol Sirup; dan Paracetamol Drop masing masing sebanyak 3 item.

Co-Authors , stf1 ., Amirudin Afief, Arief R. Akrom, Akrom Aldhi Bayu Ali, Taufik Amirudin . Andriswana, Dwi Meiria Anjastika, Luky Septiansyah Anna Pradiningsih Aribowo Aribowo ARIS ARIS, ARIS ASEP SUPARMAN Ayuditiawati, Meita Azrul Zuniarto, Ahmad Bachtiar, Arsyad Deni Firmansyah Deria, Deria Dewi, Komala Diana Agustina Didi Rohadi Dzulhijjah, Hawa Eka Putri Wulandari, Eka Putri Farhan Alfawwaz, Azriel Fatmawati, Eva Fauzia, Rizki Rahmah Febriawan, Toyyib Viat Filah Suryana Bahri Fitri Zakiah Haerunnisa, Tita HARYATI, ETI Hasimun, Patonah Husni Mubarok IIN INDAWATI Indah Setyaningsih Jajang Japar Sodik Joharudin, Ade Karphiawati, Aldilla Shalsa Karsidin, Bambang Khalifah, Tria Incky KRISNAWWATI, IKE Lela Sulastri, Lela Lestar, Puri Mardhiyyah, Cut Ainul Meiria A, Dwi Meriska, Caroline Merita Kristianti Minhatul Maula, Ajni Mundzir, O. Ahmad Nabila, Esra Reinanda Nafi'ah, Rahma Nafilah, Nella Nopitasari, Sindi noviani, Adis Nuari, Ris Ayu Nur Rahmi Hidayati, Nur Rahmi Nurhasanah, Sarah Nurkhasanah Nurkhasanah Nurkhasanah NURPATMAWATI, NURPATMAWATI Nurrahma Berlian, Febia Oktaviani, Dian Regar, Dhea Novakinanda Rizki Rahmah Fauzia Rubihatlan, Encis Sabarudin, Cecep Salafi, Akil Septiansyah, Luky Setriyadi, Dedy Sri Virgianti, Deby Subagja Subagja, Subagja Sugiharto, Anto Suharmono, Soni Sulistiorini Indriaty Sunandi, Retno Tresno Sundari, Retno T Sundari, Retno Tresno Titiek Suhardi Haripurnomo Kushadiwijaya Hidayati Tsai, Mei Ling Utami, Amanda Dwi Wahyuni, Yenny Sri Widianingsih, Nining Wiguna, Taufik Marta Zakiah, Fitri Zanki, Alfriani Melia Zuniarto, Ahmad Azrul

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