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Relationship Between Knowledge and Adherence to Antihypertensive at Public Healthcare in Banjarmasin City, Indonesia Hasniah, Hasniah; Hardiana, Hardiana; Rony, Rony; Fadillah, Aris; Erlianti, Karina; Ramadhani, Juwita
Pharmacology and Clinical Pharmacy Research Vol 9, No 2 (2024)
Publisher : Universitas Padjadjaran, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/pcpr.v9i2.55548

Abstract

Hypertension is one of the world’s most hazardous diseases since it harms the heart, brain, kidneys, and other organs. Patients’ understanding of hypertension can be the key to successful treatment. Nonadherence with antihypertensive medication is a primary cause of therapeutic failure and is considered a serious issue. The purpose of this study is to examine the association between antihypertensive knowledge and adherence at public healthcare facilities. This study employed a quantitative approach using a cross- sectional design. The purposive sampling technique determined the sample, resulting in 100 hypertensive respondents from Public Healthcare. Knowledge is the independent variable in data collection; adherence to antihypertensive medications is the dependent variable; and demographic variables are the confounding variable. We employed the HFQ (Hypertension Fact Questionnaire) and MMAS-8 (Modified Morisky Adherence Scale-8) questionnaires as data-gathering instruments. We conducted univariate, bivariate, and multivariate analyses on the data using SPSS. Based on the study’s findings, it is possible to conclude that there is a significant association between knowledge level and adherence with antihypertensive medicine use in public healthcare, with a p-value of 0.003. Comorbidities are a risk factor for hypertension that affects adherence, with a p-value of 0.007 and an OR of 0.801, indicating that patients are 0.801 times more likely to take their medicine
UJI AKTIVITAS ANTIBAKTERI DAUN JUKUT PENDUL (Kyllinga nemoralis) YANG DIPEROLEH DARI KOTABARU, KALIMANTAN SELATAN, INDONESIA Soemarie, Yulistia Budianti; Niasti, Ignalia; Hasniah
JFL : Jurnal Farmasi Lampung Vol. 13 No. 2 (2024): JFL : Jurnal Farmasi Lampung
Publisher : Program Studi Farmasi-Fakultas Matematika dan Ilmu Pengetahuan Alam-Universitas Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jfl.v13i2.1763

Abstract

The use of antibiotics as acne treatment is often used as the main treatment by the community. Natural acne treatments that are easily available should be developed to replace chemical products, such as the jukut pendul plant (Kyllinga nemoralis). The purpose of this study was to determine the antibacterial activity of jukut pendul leaves against Propionibacterium acnes. The sample was determined, extracted by maceration method using 70% ethanol, then fractionated with water, ethyl acetate, and n-hexane solvents. Phytochemical screening on ethanol extract, n-hexane fraction, ethyl acetate fraction, and water fraction. Antibacterial activity tests were conducted on extracts and fractions of jukut pendul leaves with concentrations of 5%, 10%, and 15%. Antibacterial activity testing of 5% concentration ethanol extract produced inhibition of 9.5 mm (medium), 10% 9.6 mm (medium), 15% 10.16 mm (strong). The n-hexane fraction of 5%, 10% and 15% concentration was 6 mm (medium). Ethyl acetate fraction of 5% concentration was 9 mm (medium), 10% 9.6 mm (medium), 15% 11.2 mm (strong). Water fraction of 5% and 10% concentration was 6 mm (medium), 15% concentration was 8.3 mm (medium). Keywords: Antibacterial, Jukut Pendul (Kyllinga nemoralis), Propionibacterium acnes
Ekplorasi Senyawa Ekstrak Etanol Rumput Belulang (Eleusine indica (L.) Gaertn) Menggunakan LC-MS/MS-QTOF Serta Uji Aktivitas Anti-Diare: In-Vivo Pratama, Rizki Rahmadi; Septianto, Andre; Al-Hasyimi, Said Muhammad; Herliana, Herliana; Hasniah, Hasniah; Muslikh, Faisal Akhmal
Bioscientist : Jurnal Ilmiah Biologi Vol 12, No 2 (2024): December
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v12i2.14192

Abstract

Diarrhea is one of the diseases caused by symptoms of intestinal tract infections due to various microorganisms. Goosegrass (Eleusine indica (L.) Gaertn) is a wild weed that has long been used as a traditional medicine, attributed to its phytochemical compounds such as tannins, alkaloids, flavonoids. This study aims to evaluate the antidiarrheal effects of Eleusine indica extract by comparing six treatment groups: a healthy group, a negative control group (Na-CMC), a positive control group (Loperamide 2 mg), and three variations of the extract dosage. Observations were made over 360 minutes at 30-minute intervals, using a fecal consistency scale from 1 (solid) to 5 (liquid). LC-MS/QToF analysis identified 25 secondary metabolites in the extract, including flavonoids (Schaftoside, Orientin, Vitexin, Tricin), phenolic compounds, and terpenoids. In vivo testing showed that the third dose of Eleusine indica grass extract had the most optimal antidiarrheal effect among the three doses, as evidenced by its ability to reduce diarrhea frequency, decrease fecal weight, shorten diarrhea duration, and improve fecal consistency, approaching the effectiveness of Loperamide 2 mg as a positive control. These findings suggest the potential of Eleusine indica extract as a promising natural antidiarrheal agent.
RASIONALITAS PENGGUNAAN OBAT ANTIHIPERTENSI PADA PASIEN PREEKLAMPSIA RAWAT INAP DI RSUD MUARA TEWEH PERIODE TAHUN 2023 Fahrezy, Akhmad Irghi; Hasniah, Hasniah; Fadillah, Aris
Jurnal Kesehatan Tambusai Vol. 6 No. 1 (2025): MARET 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i1.38192

Abstract

Preeklamsia merupakan salah satu bentuk hipertensi yang harus diobati dengan terapi antihipertensi selama kehamilan. Salah satu penyebab utama penyakit dan kematian pada ibu dan bayi adalah preeklampsia. Evaluasi rasionalitas Penggunaan obat penting pada pemberian obat antihipertensi bagi ibu hamil. Hal ini dilakukan guna memastikan ibu hamil telah mendapatkan terapi pengobatan yang aman, efektif, dan diperlukan secara klinis, mengingat preeklamsia merupakan penyakit yang menimbulkan risiko serius bagi ibu dan janin. Tujuan dari penelitian ini yaitu mengetahui Gambaran dan rasionalitas penggunaan obat antihipertensi pada pasien preeklampsia rawat inap di RSUD Muara Teweh Periode Tahun 2023. Penelitian ini merupakan penelitian non eksperimantal deskriptif observasional dengan menggunakan data retrospektif. Sampel dalam penelitian ini sebanyak 40 rekam medis diambil dengan menggunakan teknik Purposive sampling melalui kriteria inklusi dan eksklusi yang telah ditentukan. Data yang disajikan dalam bentuk diagram/ tabel dan persentase. Data yang diperoleh dibandingkan dengan standar acuan PNPK Preeklampsia 2016. Hasil dari penelitian ini didapatkan penggunaan nifedipin sebesar 42%, kombinasi nifedipin dan metildopa sebesar 48% yang dilanjutkan metildopa sebesar 5% dan amlodipin 5%. Rasionalitas tepat penggunaan obat didapatkan hasil tepat indikasi 98%, tepat obat 98%, tepat dosis 100%, tepat cara pemberian 100%, dan tepat interval pemberian sebesar 100%.
ANALISIS KESESUAIAN PERESEPAN OBAT PASIEN BPJS DENGAN FORMULARIUM PUSKESMAS DI PUSKESMAS PEKAUMAN KOTA BANJARMASIN PERIODE JANUARI–MARET 2024 Abdi, Muhammad; Ramadhani, Juwita; Hasniah, Hasniah; Feteriyani, Rina
Jurnal Kesehatan Tambusai Vol. 6 No. 1 (2025): MARET 2025
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/jkt.v6i1.39242

Abstract

Puskesmas adalah fasilitas pelayanan kesehatan tingkat pertama yang bertugas mengawasi dan menyelenggarakan pelayanan kesehatan promotif, preventif, kuratif, rehabilitatif, dan paliatif. Puskesmas menyelenggarakan pelayanan resep sebagai salah satu komponen pelayanan kefarmasian. Pelayanan kefarmasian yang berkualitas sangat penting untuk mendukung upaya kesehatan masyarakat individu dan program kesehatan masyarakat di pusat kesehatan. Formularium puskesmas dirancang untuk menetapkan dan mengatur obat yang digunakan dalam pengobatan, memastikan kesesuaiannya dengan penyakit dan kebutuhan obat di puskesmas. Kesesuaian terhadap formularium saat meresepkan obat sangat penting untuk meningkatkan kualitas mutu pelayanan. Resep yang tidak sesuai dengan formularium dapat berdampak buruk pada pelayanan kefarmasian yang kurang maksimal. Penelitian ini bertujuan untuk mengetahui kesesuaian peresepan obat pasien BPJS dengan Formularium Puskesmas di Puskesmas Pekauman Kota Banjarmasin Periode Januari-Maret 2024. Penelitian ini merupakan penelitian deskriptif non-eksperimental dengan data yang dikumpulkan secara retrospektif menggunakan metode systemic sampling. Populasi data penelitian diambil dari penelusuran data resep di Puskesmas Pekauman pada periode Januari 2024 – Maret 2024 dengan sampel data yang digunakan sebanyak 402 resep. Dari penelitian yang telah dilakukan ditemukan tingkat kepatuhan dalam penulisan resep sesuai dengan formularium (95,02%) jika diukur berdasarkan lembar resep, dan (98,33%) ketika diukur berdasarkan jumlah item obat pada resep. Hasil penelitian menunjukkan bahwa resep yang di analisis belum sepenuhnya memenuhi standar Formularium Puskesmas.
BURN WOUND HEALING ACTIVITY OF ETHANOL EXTRACT OF ECENG GONDOK (Eichornia crassipes) LEAVES Juwita Ramadhani; Aris Fadillah; Hasniah Hasniah; Karina Erlianti
AL ULUM: JURNAL SAINS DAN TEKNOLOGI Vol 10, No 2 (2024)
Publisher : UPT Publication and Journal Management, Islamic University of Kalimantan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/jst.v10i2.15756

Abstract

Eceng gondok is a weed plant that lives in shallow water areas. The aim of this research was to determine the burn wound healing activity of an ethanol extract of Eceng gondok leaves. The study utilized 28 male mice with burn injuries as test animals, dividing them into 4 groups. We gave a gel containing an ethanol extract to the 10% group. The 0% group received a gel base; the positive control group received Bioplacenton® gel; and the negative control group received no treatment. For 14 days, we administered treatment to all treatment and control groups once a day and measured the burn wound's diameter using the Morton method every two days. Data shown were significant differences between the 10% extract group and the positive control groups. The concentration that is effective in burn wound healing is 10%, with the smallest wound diameter and the largest healing percentage.
Long-Term Protection After Primary Hepatitis B Vaccination: A Systematic Review Hasniah, Hasniah; Perwitasari, Dyah Aryani; Supadmi, Woro
Sciences of Pharmacy Volume 4 Issue 3
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0403320

Abstract

Vaccination has proven effective in preventing HBV transmission and reducing related health burdens. This study aimed to systematically review the long-term effectiveness of the hepatitis B vaccine following primary vaccination. A literature search was conducted using PubMed, ProQuest, and the Cochrane Library following PRISMA guidelines. Keywords included "effectiveness," "hepatitis B," "HBV," "HepB," "vaccine," "vaccination," "immunization," "immune memory," "seroprotection," and "birth dose." Of 555 articles initially identified, nine met the inclusion criteria. Results showed that the duration of protection after primary vaccination ranges from 5 to 25 years, with an average seroprotection rate of 83.5%. Vaccination is vital for newborns, regardless of maternal HBV status, and healthcare professionals play a key role in promoting early immunization. Monitoring anti-HBs antibody levels is also recommended to assess the need for booster doses, which may help prevent HBV transmission and further reduce morbidity and mortality.
IMPACT OF IRON SUPPLEMENT TABLET COMPLIANCE ON HEMOGLOBIN LEVELS IN PREGNANT WOMEN Ramadhani, Juwita; Hasniah; Anggi Saputri, Mutiara
Journal of Innovation Research and Knowledge Vol. 5 No. 2: Juli 2025
Publisher : Bajang Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Iron Supplement Tablets (IST) are utilized to facilitate biological processes in the human body, particularly in hemoglobin synthesis, since the body requires iron minerals from these tablets. IST has 60 mg of iron (in the forms of Ferro Sulfate, Ferro Fumarate, or Ferro Gluconate) and 0.400 mg of Folic Acid. Administering iron supplementation therapy to pregnant women is one of the most effective methods to prevent and address nutritional anemia by elevating hemoglobin levels. This study aimed to assess the impact of adherence to IST consumption and the factors influencing hemoglobin levels in pregnant women. This research employs a quantitative methodology with a prospective design. This study employs a cross-sectional approach, wherein data is collected simultaneously during the distribution of the MARS-5 questionnaire scale. The population of 429 was determined using the Lemes Show formula, yielding 60 respondents. The results indicated that among 60 respondents, compliance among pregnant women was high (1.7%), moderate (90%), and low (8.3%). The study findings indicate that among pregnant women, 41.7% exhibited normal hemoglobin levels, 28.3% had mild anemia, 18.3% presented with moderate anemia, and 8.3% experienced severe anemia. The findings of this study indicated the impact of adherence to IST consumption on hemoglobin levels, with a chi-square test yielding a P-value of (<0.001). Additionally, parity factors influenced compliance with IST consumption, as evidenced by a chi-square test resulting in a P-value of (0.010).
THE CONTRIBUTION OF ISLAMIC RELIGIOUS EDUCATION (PAI) MATERIALS TO THE DEVELOPMENT OF STUDENTS’ TOLERANT AND INTEGRATIVE ATTITUDES Hasniah, Hasniah; Fuad, Misbahul
PROCEEDING OF INTERNATIONAL CONFERENCE ON EDUCATION, SOCIETY AND HUMANITY Vol 3, No 1 (2025): First International Conference on Education, Society and Humanity
Publisher : PROCEEDING OF INTERNATIONAL CONFERENCE ON EDUCATION, SOCIETY AND HUMANITY

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This research aims to analyze the contribution of Islamic Education materials in developing students' tolerant and integrative attitudes. The research method employs a qualitative approach with library research that analyzes relevant literature from the 2021-2025 period. The research findings indicate that Islamic Education materials have comprehensive dimensions in forming students' tolerant character through the concept of tasamuh and universal Islamic values. The implementation of religious moderation in Islamic Education learning proves effective in developing balanced and inclusive religious attitudes. The development of integrative attitudes occurs systematically through the internalization of contextual Islamic values. Factors influencing the success of implementation include teacher competence, institutional support, student characteristics, and socio-cultural context. This research recommends curriculum reform, teacher competence enhancement, and strengthening the synergy of educational tri-centers to optimize the contribution of Islamic Education materials in forming students' tolerant and integrative character sustainably.
HUBUNGAN TINGKAT PENGETAHUAN PASIEN HIPERTENSI TERHADAP KEPATUHAN MINUM OBAT ANTIHIPERTENSI DI RUMAH SAKIT UMUM DAERAH ULIN BANJARMASIN Nurhidayah, Nurhidayah; Fadillah, Aris; Hasniah, Hasniah
JFM (Jurnal Farmasi Malahayati) Vol 8, No 2 (2025)
Publisher : Jurnal Farmasi Malahayati (JFM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jfm.v8i2.19567

Abstract

Hipertensi menjadi masalah kesehatan utama di Indonesia, dengan prevalensi tertinggi di Kalimantan Selatan. Di Banjarmasin, tercatat 18.942 kasus baru pada 2023. Kepatuhan pasien dalam pengobatan jangka panjang masih menjadi tantangan, meskipun berperan penting dalam peningkatan kualitas hidup. Penelitian ini bertujuan menganalisis hubungan antara tingkat pengetahuan pasien hipertensi dan kepatuhan minum obat di RSUD Ulin Banjarmasin. Penelitian deskriptif kuantitatif dengan desain cross-sectional ini melibatkan 185 responden yang dipilih secara purposive non-random. Data dikumpulkan menggunakan kuesioner HFQ dan MMAS-8, kemudian dianalisis dengan uji chi-square. Hasil menunjukkan hubungan signifikan antara pengetahuan dan faktor sosio-demografi seperti pekerjaan (p=0,002) dan pendidikan (p=0,000), namun tidak dengan umur (p=0,060) atau jenis kelamin (p=0,241). Kepatuhan berhubungan dengan jenis kelamin (p=0,026), pekerjaan (p=0,000), dan pendidikan (p=0,000), tetapi tidak dengan umur (p=0,430). Selain itu, terdapat hubungan signifikan antara tingkat pengetahuan dan kepatuhan (p=0,000). Dapat disimpulkan pengetahuan pasien hipertensi berhubungan dengan pekerjaan dan pendidikan serta berperan dalam meningkatkan kepatuhan terhadap pengobatan
Co-Authors Abdul jalil Abdullah Igo BD Al-Hasyimi, Said Muhammad Ali Hadara Andryanto, M. Hasan Andryanto, Muhammad Hasan Anggi Saputri, Mutiara Aris Fadillah Ashmarita, - Asriyani Mulia Basri Aziz, Ifran Devi, Desriati Dewi Marianthi Didi Susanto Didi Susanto, Didi Dini Susanti Dyah Aryani Perwitasari Eko Nursalim, Eko Erens E. Koodoh Erlianti, Karina Erni Fahrezy, Akhmad Irghi Faisal Akhmal Muslikh Fathimi, Fathimi Fauzi Rahman Fauzi Rahman Febriyani, Henda Feteriyani, Rina Fitri Apriliany, Fitri Fuad, Misbahul Fuzi Maulana Ash'ari Hardiana, Hardiana Harjun, Harjun Hasniar Hasniar, Hasniar I Ketut Suardika Ilhamurrahman M Hubaib Jafar Ahiri Jannah, Mursidatul Jumatin Juwita Ramadhani Juwita, Ramadhani Karina Erlianti karina erlianti Karina Erlianti Karina Erlianti Karina Erlianti Karina Erlianti Karina, Erlianti Khojir Kurnia, Ina La Ode Safiun Arihi Lathifah Hanum, Lathifah Laxmi Lia Mardiana M Hasan, Andryanto M. Yogi Riyantama Isjoni Mardiana, Lia Moh. Anas Muh Fathul Ikrar Muh. Alkautsar Muh. Ilham Muhammad Abdi, Muhammad Muhammad Fauzi Muhammad Juwantho Lewa Muhammad Syukur Muhammad, Fauzi Muliyani Muliyani Murni Nia Murni Nia Murniati Nadillah, Gita Fannia Nafsiyah, Faizatun Naimah, Roudhatun Niasti, Ignalia Noriandani, Riska Ayu Nur ‘Azah Nurhidayah Nurhidayah Nurwijayanti Oetama, Saiful Perwitasari , Dyah Ariani Putri, Ayu Aprilia Pangestu Qibthiyah, Mariatul Raemon Ramly Ramly Riska Ayu, Noriandani Ritawati Ritawati Rizal Rizal Rizki Rahmadi Pratama Rony, Rony RR. Ella Evrita Hestiandari Sabillah, Bellona Mardhatillah Sahibu Sahibu Sasmita, Yenni Septiana, Rahma Rizkiya Septianto, Andre Simeulu, Putro Sitio, Roma Sjamsir, Hasbi Soemarie, Yulistia Budianti Su'aida, Nily Sugeng Sugeng Supadmi , Woro suratman Su’aida, Nily Syahidah, Annisa Syamsuddin, Asniah Tri Zahra Ningsih Wa Ode Fazri Samsinar Wahyu Muh Syata Woro Supadmi Yasmin Saul Sambolayuk Yulistia Budianti Soemarie Yulistia Budianti, Soemarie Zainal