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Journal : Pharmacoscript

COST-EFFECTIVENESS DEXKETOPROFEN VS KETOROLAC IN CAESAREAN PATIENTS AT 'X' HOSPITAL, PANDEGLANG Yusransyah, Yusransyah; Sofi Nurmay, Stiani; Farahdina, Chairani; Latifah Nur, Rizki; Baha, Udin
Pharmacoscript Vol. 8 No. 2 (2025): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v8i2.2150

Abstract

Post-cesarean section pain must be treated promptly and appropriately to prevent chronic conditions. Dexketoprofen and Ketorolac are non-narcotic analgesics commonly used to manage such pain. This study aimed to analyse the cost-effectiveness of dexketoprofen and ketorolac in patients undergoing cesarean sections at Mother and Child Hospital "X" in Pandeglang. The study used a cross-sectional design with cost-effectiveness analysis, specifically the Average Cost-Effectiveness Ratio (ACER). Pain intensity was measured one hour after surgery using the Faces Pain Rating Scale and Visual Analog Scale (VAS). Inclusion criteria were patients who underwent cesarean section and received non-narcotic analgesics. A total of 90 patients participated: 39 in the dexketoprofen group and 51 in the ketorolac group. Data were analyzed using ACER and the Mann-Whitney test. The ACER, based on the Faces Pain Rating Scale, showed a cost of IDR 1,142 for the dexketoprofen group and IDR 958.03 for the ketorolac group. Using the VAS, the cost was IDR 1,110 for dexketoprofen and IDR 657.45 for ketorolac. Statistical results showed a p-value < 0.05 for both pain measurement tools, indicating a significant difference in effectiveness between the two therapies. Based on both instruments, ketorolac was more cost-effective than dexketoprofen in managing post-cesarean section pain. This finding suggests that ketorolac may be a preferable option in clinical settings where cost and effectiveness are key considerations for post-operative analgesia in cesarean section patients.
FORMULATION AND ANTIBACTERIAL ACTIVITY OF LIQUID SOAP FROM KECOMBRANG STEM EXTRACT (Etlingera elatior) AGAINST Staphylococcus aureus Syilvi, Adini; Miftah, Miftah; Yusransyah, Yusransyah; Sofi Nurmay, Stiani
Pharmacoscript Vol. 9 No. 1 (2026): Pharmacoscript
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat, Universitas Perjuangan Tasikmalaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36423/pharmacoscript.v9i1.2261

Abstract

Kecombrang (Etlingera elatior) is a plant used by the Baduy ethnic group as a substitute for soap to cleanse the skin and exhibit antibacterial activity. Staphylococcus aureus is the cause of skin infections. Liquid soap is a type of soap that can protect the skin against microorganisms, generally caused by S. aureus. This study aims to develop an antibacterial liquid soap containing kecombrang stem extract, in accordance with the quality requirements of liquid soap, and to determine its antibacterial activity against S. aureus. The extract is formulated into four liquid soap formulas, namely F0, F1, F2, and F3. Physical evaluations include organoleptic properties, homogeneity, pH, liquid soap foam height, viscosity, free alkali content, specific gravity, and antibacterial tests using the well diffusion method. In the organoleptic test, the liquid preparation is brown and has a distinctive odor, with a pH value of around 10.61 to 10.85. The foam height ranges from 33 to 93 mm, viscosity is 412 to 489 cP, specific gravity is 1.02 to 1.08, and free alkali content is 0.05 to 0.16%. Liquid soap with ethanol extract from kecombrang stem inhibits the growth of S. aureus bacteria, with inhibition zones of 9.2 mm for F1, 14.8 mm for F2, and 16 mm for F3, all with p-values <0.05. All formulas met the quality requirements for liquid soap, and F3 (17% extract) demonstrated the highest antibacterial activity.
Co-Authors Abdillah , Mursyid Abdillah Mursyid Ade Anwar Adini, Syilvi Aditia Saeffurrohman Afifah Nur Shobah Ahmad Sofan Ai Yeni Herlinawati Andri Harpan Anita Nugraheni, Diesty Anjani, Shabrina Talitha Asep Salman Alfarizqi Ashari, Elva Febri Aulia, Ayu Ayuni, Eka Sirly Baha Udin Bahaudin Bahaudin Bahaudin Bahaudin, Bahaudin Banu Kuncoro Cahya, Wulan Candra Junaedi Chairani, Farahdina Dewi Intan Sri Rahayu Diesty Anita Nugraheni Dina Pratiwi S.farm, M.Sc Effendi, Erwin Endah Endah endah, endah Endang Safitri Eneng Elda Ernawati Eneng Elda Ernawati Epinur Epinur Eva Kholifah Eva Kholifah Fajrin Noviyanto Fajrin Noviyanto Fajrin Noviyanto, Fajrin Farahdina Chairani Farahdina, Chairani Fathiyati Fathiyati Fauzi, Andrian Maulana Fauzy, Adrian Maulana Ferdiyansyah, Ferdiyansyah Fifih Lutfiyah Hadi Susilo Hakim, Imam Lukmanul Hanifah Dwi Safitri Harpan, Andri Hasanah, Indah Ayu Nur Herawati, Fera Imam Lukmanul Hakim Imas Masfuah Indriatmoko, Dimas Danang Ismiyati, Renditya Jovita Almira Kelutur, Faruk Jayanto Kholifah, Eva Kuncoro, Banu Kurnia, Nia Marlina Latif , Yudha Aditama Latif Yudha Aditama Latifah Nur, Rizki Leni Halimatusyadiah Lia Khaerunnisa Lukmanul Hakim, Imam Lydya Elfira Sari Nasution Maharani, Sylvianti Maharani, Zahra Citra Marlina, Nia Masfuah, Imas Meila Pertiwi Miftah Miftah, Miftah Mohammad Rizal Mohammad Rizal, Mohammad Muhamad Ichsan Fahlevy Muhammad Nurmiftahuddin Mulyani, Yani Mulyani Murdianto, Yudi Mursyid, Abdillah Nabillah, Deya Adiby Nana Suryana Nasiti, Febriane Dwi Nia Marlina Nur Insani Nur Shobah, Afifah Nuraini M.Farm, Apt Nurani, Agnes Wieanita Nurhayati, Ghina Siti Nurhikmah, Ihda Nuriyatul Fhatonah Nurul Fitri, Nabila Nurul Insani Ofsah, Olin Najilah Oktaviana Hadi, Agriyaningsih Perdi, Perdi Pratiwi, Linda Rani Pratiwi, Rossi Pujiati, Devi Putri, Nabila Septiani Rahmawida Putri Rahmawida Putri Raiyan Renditya Ismiyati Renditya Ismiyati Reza Sudrajat Ristiani, Yuanisa Rizki Robul Izati Rizkiana, Muhammad Dinta Rozwaliza Annintan Rustiyani, Risa Sabilla, Aliffia Nur Saeffurrohman, Aditia Saepudin Saepudin Salsabillah, Audy Nursifa'atun Seira, Trisya Selviani, Astri Septina Sumantri, Aulia Setiawan, Abdul Aziz Shabrina Talitha Anjani Shirly Kumala Shobah, Afifah Nur Siswa Setyahadi Siti Hodijah Siti Lailatu Zahroh Siti Rhopi’ah Sofi Nurmay Stiani Soraya Uli, Elisabeth Stiani, Sofi Nurmay Subchan, Mohamad Sumarlin US Sumarlin US Syifa Maulidia Rizqi Syilvi Adini Sylvi Addini Sylvianti Maharani Teguh Sudarto Tuty Sriwahyuni US, Sumarlin Wibirezkina, Aufalya Yulistina, Isti Yuni Rahmawati Yuningsih Yuningsih Zulfiani, Nia