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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Brawijaya Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Cancer Chemoprevention Jurnal Sains dan Teknologi Farmasi Indonesian Journal of Pharmaceutical Science and Technology EduChemia: Jurnal Kimia dan Pendidikan Acta Pharmaceutica Indonesia Jurnal Farmasi Sains dan Komunitas Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) JPSCR : Journal of Pharmaceutical Science and Clinical Research Abditani : Jurnal Pengabdian Masyarakat Jurnal Ilmu Kefarmasian Indonesia JURNAL FARMASIMED (JFM) Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Jurnal Peduli Masyarakat Borneo Journal Of Pharmascientech Poltekita: Jurnal Pengabdian Masyarakat Jurnal Ilmiah Pharmacy MEDIC MEdical Dedication SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Indonesian Journal of Pharmaceutical Education Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Pharmaceutical Care and Sciences Prosiding Seminar Nasional Pengabdian Kepada Masyarakat Sciences of Pharmacy Panthera : Jurnal Ilmiah Pendidikan Sains dan Terapan Jurnal Katalisator Riset Informasi Kesehatan Jurnal Pengabdian Harapan Ibu (JPHI) Journal of Pharmaceutical and Sciences. Jurnal Kedokteran Meditek Prosiding Seminar Nasional Unimus Borneo Journal of Pharmacy Bencoolen Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan Jurnal Abdimas Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Galen: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Kesehatan Farmasi Nusantara Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Journal of Pharmascience
Sani K, Fathnur
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Analysis of Psychotropic Drug Utilization in Patients With Organic Mental Disorders Yuliawati, Yuliawati; Sofyan, Indah Sri Wulan; Sadli, Nurul Kamilah; Kasmadi, Fathnur Sani
Sciences of Pharmacy Volume 5 Issue 2
Publisher : ETFLIN

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0502576

Abstract

Organic mental disorders are psychiatric conditions caused by identifiable brain pathology or specific systemic diseases, characterized by psychotic, affective, anxiety, and cognitive symptoms that can impair daily functioning. Psychotropic medications play a central role in their management; however, data on utilization patterns, particularly among outpatients in regional psychiatric hospitals, remain limited. This study aimed to quantitatively evaluate the use of psychotropic drugs using the Anatomical Therapeutic Chemical/Defined Daily Dose (ATC/DDD) method recommended by the World Health Organization, and to identify drugs within the Drug Utilization 90% (DU90%) segment to support rational drug use. This retrospective descriptive study utilized secondary data from medical records of outpatients diagnosed with organic mental disorders at Kolonel H. M. Syukur Regional Psychiatric Hospital, Jambi, in 2024, with a total sampling of 100 patients. The results showed that the total psychotropic drug utilization was 9.89 DDD per patient per day. Antipsychotics were the most frequently used class, followed by antidepressants and anxiolytics. The DU90% segment consisted of eleven drugs, predominantly atypical antipsychotics, selective serotonin reuptake inhibitors (SSRIs), and benzodiazepines, with olanzapine, escitalopram, fluoxetine, and alprazolam being the most commonly prescribed. Most patients were male, in the productive age group, and diagnosed with unspecified organic mental disorders. Overall, the pattern of psychotropic drug utilization reflects the complexity of clinical manifestations in organic mental disorders and underscores the importance of monitoring drug use to promote rational prescribing practices in clinical settings.
Anti-Tuberculosis Drug Adherence Among Pulmonary Tuberculosis Patients At Primary Health Center Zannah, Junnia Aulia; Yuliawati, Yuliawati; Efendi, M Rifqi; Pondawinata, Marizki; Sani, Fathnur
Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Vol. 14 No. 1 (2026): JAMBI MEDICAL JOURNAL: Jurnal Kedokteran dan Kesehatan
Publisher : FAKULTAS KEDOKTERAN DAN ILMU KESEHATAN UNIVERSITAS JAMBI

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22437/jmj.v14i1.48086

Abstract

Background: Tuberculosis (TB) is an infectious disease caused by infection with the bacterium Mycobacterium tuberculosis (M. tb). This bacterium has characteristics that make it difficult to treat, resulting in prolonged TB therapy. Non-adherence to anti-tuberculosis drugs (ATD) may increase the risk of treatment failure in patients diagnosed with pulmonary TB, which in turn can elevate the risk of multidrug resistance (MDR). Method: This study is a descriptive observational research with a cross-sectional design and consisted of 45 participants. The research instrument used was the MMAS-8 (Morisky Medication Adherence Scale) questionnaire. Univariate and bivariate analyses were performed using the Chi-Square test. Result: The results showed that 34 respondents (75.6%) had a high level of adherence, 9 respondents (20%) had a moderate level of adherence, and 2 respondents (4.44%) had a low level of adherence. According to statistical analysis using the Chi-Square test, the significance value for gender and adherence was 0.822, for age and adherence was 0.031, for educational level and adherence was 0.445, and for occupation and adherence was 0.465. Conclusion: The majority of TB patients at Puskesmas Kenali Besar demonstrated a high level of adherence.
Aplikasi Serum Nanoekstrak Daun Pucuk Merah (Syzigium myrtifolium Walp.) Terenkapsulasi Nanopartikel sebagai Antioksidan Lestari, Uce; Sani, Fathnur; Muhaimin, Muhaimin; Yuliana, Yuliana; Mekeama, Luri
JPSCR: Journal of Pharmaceutical Science and Clinical Research Vol 11, No 1 (2026)
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/jpscr.v11i1.109730

Abstract

Perkembangan sistem penghantaran berbasis nanoteknologi dalam bidang kosmetik semakin meningkat, salah satunya melalui serum nanoekstrak yang mampu meningkatkan stabilitas dan efektivitas bahan aktif terutama yang berasal dari bahan alam seperti Nanoekstrak Daun Pucuk Merah (Syzigium myrtifolium Walp). Senyawa flavonoid dan fenolik pada ekstrak Daun Pucuk Merah memiliki aktivitas antioksidan tinggi, namun rentan mengalami degradasi akibat paparan cahaya dan oksidasi. Penelitian ini bertujuan untuk memperoleh formula serum nanoekstrak daun pucuk merah dengan karakteristik fisik dan aktivitas antioksidan terbaik. Nanoekstrak diformulasikan menggunakan metode gelasi ionik dengan polimer kitosan dan alginat serta natrium tripolifosfat sebagai crosslinker, selanjutnya di formulasi dalam sediaan serum. Hasil karakterisasi menunjukkan ukuran partikel berada pada rentang 135,5-194,4 nm dengan nilai PDI pada rentang 0,463-0,991 dan rentang zeta potensial -23,7 mV s.d -25,6 mV. Formula Nanoekstrak Daun Pucuk Merah (NDPM) menunjukkan aktivitas antioksidan sangat kuat dengan nilai IC50 sebesar 1,86 ppm, lebih baik dibandingkan ekstrak daun pucuk merah tanpa formulasi nanoteknologi yang memilik nilai IC50 sebesar 6,16 ppm. Formula II Serum Nanoekstrak Daun Pucuk Merah (SNDPM) dengan berat ekstrak 0,28 g menghasilkan karakteristik fisik, stabilitas dan aktivitas antioksidan yang terbaik. Serum Nanoekstrak Daun Pucuk Merah (SNDPM) berpotensi dikembangkan sebagai kosmetik alami yang inovatif, aman, dan ramah lingkungan untuk melindungi kulit dari radikal bebas dan paparan sinar ultraviolet.
Optimization Formula and SPF Test of Lotion from Essential Oil of Patchouli Leaves (Pogostemon cablin Benth.) Anjaly Rizkya Fazariana; Fathnur Sani K; Indri Maharini
Jurnal Farmasi Sains dan Komunitas (Journal of Pharmaceutical Sciences and Community) Vol 22, No 2 (2025)
Publisher : Sanata Dharma University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24071/jpsc.008439

Abstract

An increase in the ultraviolet (UV) index poses severe health risks by inducing harmful effects on the skin, such as sunburn, erythema, skin darkening, premature ageing, and skin cancer. These risks are mitigated through sunscreens with high Sun Protection Factor (SPF) values (15). Natural sources of high SPF include patchouli leaf essential oil, which contains flavonoids. Flavonoid compounds with double bonds can absorb UV-A and UV-B rays, protecting against their harmful effects. The purpose of this study was to find the best formula and observe its impact on the physical characteristics of the preparation and SPF activity. Formula optimization used Design Expert software 13 with the simplex lattice design method. The optimized variables were TEA and stearic acid as emulsifying agents. The results of the optimum formula composition consisted of 4% TEA and 5% stearic acid. The optimum skin protection lotion preparation has a yellow color, a distinctive smell of patchouli oil, a semi-solid shape and a thick texture. The pH parameters of 7.7±0.09, adhesion of 2.34±0.06 seconds, spreadability of 6.85±0.02 cm and viscosity of 4503.3±219.39 Cp. Patchouli leaf essential oil and lotion have ultra-category SPF values with oil SPF value of 27.86±1.07 and lotion preparation of 27.65±1.75 preparation is also homogeneous with pH parameters of 7.7±0.09, adhesion of 2.34±0.06 seconds, spreadability of 6.85±0.02 cm and viscosity of 4503.3±219.39 Cp. Patchouli leaf essential oil and lotion have ultra-category SPF values with oil SPF value of 27.86±1.07 and lotion preparation of 27.65±1.75.
Co-Authors Adisty, Aura Rasyanda Afryandes, Amelya Agung Giri Samudra Agung Giri Samudra Agung Giri Samudra Agung Giri Samudra Agung Giri Samudra Aina Fatkhil Haque Alfi Khatib Amalia Nasution, Riska Andriani, Annisa Anggia, Sonia Anggraini, Dewi Febrina Anjaly Rizkya Fazariana Annisa Luthfiyyah Apriza Hongko Putra Asima Widyawaty Sinurat Ave Olivia Rahman Ave Olivia Rahman Ave Olivia Rahman Ave Olivia Rahman Bambang Hernawan Nugroho Bella Pascila Bernike Anatasya Cassa de Floris Cathelya, Bunga Cyntia Dwi Utami Daffa Akrama Yuda Danuartha, Dhimas Dara Permata Sari dewi, hasna Diah Riski Gusti Diah Tri Utami Diah Tri Utami DIAN LESTARI Dian Magfirah Dinofitri, Hanifah Dominica, Dwi Dwikanti Prindani Putri Dyah Fitriani Efendi, M. Rifki Ekaputri, Tia Wida Elisma Elisma Elisma Elisma Elisma Elisma Elisma Elisma Elisma Enda Oktri Mayora Evi Maryanti Febriyani, Ulfa Fitrianingsih Fitrianingsih Fitrianingsih Fitrianingsih Gatot Prasetya Gina Lestari Gina Lestari, Gina Haque, Aina Fatkhil Hasnaul Maritsa Havizur Rahman Havizur Rahman Havizur Rahman Havizur Rahman Herlina Herlina herlina herlina Humaryanto Humaryanto Humaryanto Humaryanto Humaryanto Humaryanto, Humaryanto Idamanda, Rahma Intan Lestari Iskandar, Mirna Marhami Jannah, Miptakul Jannah, Zahratul Joevanda, Salsabila Kristin Simamora Luri Mekeama M. Rifqi Efendi Maharini, Indri Maimum Maulida, Dafa Riska Mayora, Enda Oktri Melisa Putri Mesa Sukmadani Rusdi Monic Sri Cahnia Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhammad Syukri Nada Afrilia Naurah Nazifah Nazar, Armenia Neldi, Vina Novia Tri Astuti Nurfadilah Nurfadilah Nurfijrin Ramadhani Nurfijrin Ramadhani, Nurfijrin nurwani purnama aji Oktarina, Widiawati Pondawinata, Marizki Puspa Dwi Pertiwi Puspa Dwi Pratiwi Puteri, Vanya Gita Putri Aulia, Bilqis Putri, Andinni Putri, Azelia Putri, Fadilla Aliyah Putri, Kresentia Qiftiah, Mariatul Rahayu, Stepania Dwimulia Rahman , Ave Olivia Rahman, Havizur Rahman, Havizur Rahmila Yuni Astika Raudhatul Jannah Revis Asra Revis Asra Reza Pertiwi Reza Pertiwi Reza Yolandini Rizamevia, Fhidila Sadli, Nurul Kamilah Salsabilla, Navira Santi Perawati, Santi Sari, Dara Permata Sari, Indah Septi Hariyani Sofyan, Indah Sri Wulan Syamsul Arifin Syamsurizal Syamsurizal - - syamsurizal syamsurizal Tia Wida Eka Putri Uce Lestari Uce Lestari Uce Lestari Uce Lestari Uce Lestari 1 Ulfa Febriyani Usna, Rozatul Vanika, Niken Widiawati Oktarina Wirahmi, Nori Yesi Nursofia Yolandini, Reza Yudha Putra, Diky Okta Yuliana Yuliana Yuliana Yuliana Yuliandani, Yuliandani Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati, Yuliwati Zannah, Junnia Aulia