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All Journal Jambi Medical Journal : Jurnal Kedokteran dan Kesehatan Jurnal Kedokteran Brawijaya Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice) Pharmaciana: Jurnal Kefarmasian Indonesian Journal of Cancer Chemoprevention Jurnal Sains dan Teknologi Farmasi Indonesian Journal of Pharmaceutical Science and Technology EduChemia: Jurnal Kimia dan Pendidikan Acta Pharmaceutica Indonesia Pharmascience Jurnal Farmasi Sains dan Komunitas Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Majalah Farmasi dan Farmakologi (Trends in Pharmacy and Pharmaceutical Sciences) Abditani : Jurnal Pengabdian Masyarakat Jurnal Ilmu Kefarmasian Indonesia JURNAL FARMASIMED (JFM) Dharma Raflesia : Jurnal Ilmiah Pengembangan dan Penerapan IPTEKS Jurnal Peduli Masyarakat Borneo Journal Of Pharmascientech Poltekita: Jurnal Pengabdian Masyarakat Jurnal Ilmiah Pharmacy MEDIC MEdical Dedication SCIENCE : Jurnal Inovasi Pendidikan Matematika dan IPA Indonesian Journal of Pharmaceutical Education Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Journal of Pharmaceutical Care and Sciences Prosiding Seminar Nasional Pengabdian Kepada Masyarakat Sciences of Pharmacy Panthera : Jurnal Ilmiah Pendidikan Sains dan Terapan Jurnal Katalisator Riset Informasi Kesehatan Jurnal Pengabdian Harapan Ibu (JPHI) Journal of Pharmaceutical and Sciences. Jurnal Kedokteran Meditek Prosiding Seminar Nasional Unimus Borneo Journal of Pharmacy Bencoolen Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Sains dan Kesehatan Jurnal Abdimas Kesehatan Jurnal Ilmiah Manuntung: Sains Farmasi dan Kesehatan Galen: Jurnal Ilmu Farmasi dan Kesehatan Jurnal Kesehatan Farmasi Nusantara Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Sani K, Fathnur
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Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Uji Iritasi Dan Uji Hedonik Sediaan Mouth Nanospray Berbasis Minyak Atsiri Jintan Hitam (Nigella Sativa L.) Septi Hariyani; Uce Lestari; Fathnur Sani K; Elisma
Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan Vol. 2 No. 1 (2026): Galen: Jurnal Riset Ilmu Farmasi dan Kesehatan
Publisher : PT Pustaka Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.71417/galen.v2i1.137

Abstract

Bau mulut (halitosis) merupakan salah satu masalah kesehatan mulut yang dapat memengaruhi kepercayaan diri seseorang. Salah satu upaya untuk mengatasi halitosis adalah dengan pengembangan sediaan mouth spray berbasis teknologi nano menggunakan minyak atsiri jintan hitam (Nigella sativa L.) yang memiliki aktivitas antibakteri terhadap Streptococcus mutans. Penelitian ini bertujuan untuk mengetahui keamanan dan tingkat penerimaan sensori sediaan mouth nano spray berbasis minyak atsiri jintan hitam melalui uji iritasi dan uji hedonik. Uji iritasi dilakukan pada 30 relawan dengan parameter kemerahan, gatal, dan alergi, sedangkan uji hedonik dilakukan untuk menilai rasa, aroma, kesegaran, dan kenyamanan menggunakan skala Likert. Hasil uji iritasi menunjukkan bahwa 90% relawan tidak mengalami reaksi iritasi, dengan skor total 3,06 yang termasuk kategori aman digunakan. Hasil uji hedonik menunjukkan tingkat penerimaan yang sangat baik, dengan mayoritas panelis memberikan penilaian “suka” hingga “sangat suka” terhadap semua parameter sensori. Berdasarkan hasil tersebut, dapat disimpulkan bahwa sediaan mouth nano spray berbasis minyak atsiri jintan hitam (Nigella sativa L.) aman digunakan dan memiliki daya terima yang tinggi sehingga berpotensi dikembangkan sebagai produk alami penyegar mulut.
Ethanolic Extract of Curcuma zedoaria Enhances Burn Wound Healing in Male White Rats Yuliawati, Yuliawati; Kasmadi, Fathnur Sani; Elisma, Elisma; Dewi, Hasna; Afryandes, Amelya; Puteri, Vanya Gita
Sciences of Pharmacy Volume 5 Issue 1
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0501488

Abstract

In addition to its widespread use as a culinary spice, white turmeric rhizome (Curcuma zedoaria (Christm.) Roscoe) exhibits important pharmacological activities, including anti-inflammatory, anticancer, and antioxidant effects. The rhizome contains secondary metabolites such as flavonoids, alkaloids, saponins, phenols, tannins, and terpenoids, which are believed to contribute to its potential efficacy in treating burns. This study used a fully randomized post-test-only control group design consisting of five treatment groups: P1 (5% ethanol extract of white turmeric rhizome), P2 (10%), P3 (15%), K⁺ (positive control: Bioplacenton), and K⁻ (negative control: Vaseline flavum). Parameters observed included reduction in burn wound diameter and collagen density, which were assessed through histological analysis. The results showed significant differences between treatment groups (p < 0.05). The 10% concentration showed the highest wound healing activity, reaching a healing rate of 54.72% and producing denser collagen compared to the other treatments. However, its effect did not exceed the positive control (Bioplacenton). The 5% concentration showed moderate healing activity (43.84%) with intermediate collagen density, while the 15% concentration produced the lowest effect. Overall, the findings indicate that the ethanol extract of white turmeric rhizome, particularly at a concentration of 10%, enhances burn wound healing and increases collagen formation, supporting its potential as a natural therapeutic agent for the treatment of burns.
Co-Authors Adisty, Aura Rasyanda Afryandes, Amelya Agung Giri Samudra Agung Giri Samudra Agung Giri Samudra Agung Giri Samudra Agung Giri Samudra Aina Fatkhil Haque Alfi Khatib Amalia Nasution, Riska Andriani, Annisa Anggia, Sonia Anggraini, Dewi Febrina Annisa Luthfiyyah Apriza Hongko Putra Asima Widyawaty Sinurat Ave Olivia Rahman Ave Olivia Rahman Ave Olivia Rahman Ave Olivia Rahman Bambang Hernawan Nugroho Bella Pascila Bernike Anatasya Cassa de Floris Cathelya, Bunga Cyntia Dwi Utami Daffa Akrama Yuda Danuartha, Dhimas Dara Permata Sari dewi, hasna Diah Riski Gusti Diah Tri Utami Diah Tri Utami DIAN LESTARI Dian Magfirah Dinofitri, Hanifah Dominica, Dwi Dwikanti Prindani Putri Dyah Fitriani Efendi, M. Rifki Elisma Elisma Elisma Elisma Elisma Elisma Elisma Elisma Elisma Elisma Elisma Elisma Elisma Enda Oktri Mayora Evi Maryanti Fazariana, Anjaly Rizkya Febriyani, Ulfa Fitrianingsih Fitrianingsih Fitrianingsih Fitrianingsih Gatot Prasetya Gina Lestari Gina Lestari, Gina Haque, Aina Fatkhil Hasnaul Maritsa Havizur Rahman Havizur Rahman Havizur Rahman Herlina Herlina herlina herlina Humaryanto Humaryanto Humaryanto Humaryanto Humaryanto Humaryanto, Humaryanto Huntari Harahap Idamanda, Rahma Intan Lestari Iskandar, Mirna Marhami Jannah, Miptakul Jannah, Zahratul Joevanda, Salsabila Kristin Simamora Kusdiyah, Erni M. Rifqi Efendi Maharini, Indri Maimum Maulida, Dafa Riska Mayora, Enda Oktri Melisa Putri Mesa Sukmadani Rusdi Monic Sri Cahnia Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhaimin Muhammad Farhan Muhammad Syukri Nada Afrilia Naurah Nazifah Nazar, Armenia Neldi, Vina Nori Wirahmi Novia Tri Astuti Nurfadilah Nurfadilah Nurfijrin Ramadhani Nurfijrin Ramadhani, Nurfijrin nurwani purnama aji Oktarina, Widiawati Pondawinata, Marizki Puspa Dwi Pertiwi Puspa Dwi Pratiwi Puteri, Vanya Gita Putri Aulia, Bilqis Putri, Andinni Putri, Fadilla Aliyah Putri, Kresentia Qiftiah, Mariatul Rahayu, Stepania Dwimulia Rahman , Ave Olivia Rahman, Havizur Rahman, Havizur Rahmila Yuni Astika Raudhatul Jannah Revis Asra Revis Asra Reza Pertiwi Reza Pertiwi Reza Yolandini Rizamevia, Fhidila Sadli, Nurul Kamilah Salsabilla, Navira Santi Perawati, Santi Sari, Dara Permata Sari, Indah Septi Hariyani Syamsul Arifin Syamsurizal Syamsurizal - - syamsurizal syamsurizal Tia Wida Eka Putri Uce Lestari Uce Lestari Uce Lestari Uce Lestari Uce Lestari 1 Ulfa Febriyani Usna, Rozatul Vanika, Niken Widiawati Oktarina Yesi Nursofia Yolandini, Reza Yudha Putra, Diky Okta Yuliana Yuliana Yuliandani, Yuliandani Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati Yuliawati, Yuliwati