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Uji In-Vitro Hidroksiapatit Berpori Menggunakan Larutan Simulated Body Fluid (SBF) Dengan Variasi Penambahan Pati Kentang Deska Deska; Ahmad Fadli; Zultiniar Zultiniar
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 6 (2019): Edisi 2 Juli s/d Desember 2019
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains

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One method of biological hydroxyapatite testing is in vitro, which is testing material outside the system or not directly on living things. Some ways include using cell culture media, test tubes or Simulated Body Fluid (SBF) solutions. The purpose of this study was to test in-vitro porous hydroxyapatite with variations in potato starch using a Simulated Body Fluid (SBF) solution. This research was conducted by mixing 4 and 6 grams of potato starch with 12 grams of HA, 35 mL aquadest. The slurry is stirred at 150 rpm for 3 hours. Then the slurry is put into a mold and dried in an oven at 80˚C for 24 hours and 120˚C for 8 hours. The dried green bodies are burned at 600°C and the sintering process at 1250°C. Furthermore porous hydroxyapatite was soaked using the SBF solution for 28 days. Samples were analyzed using XRD analysis and SEM analysis. Based on SEM analysis apatite layers were formed in all samples. Samples had an average pore diameter of 96.66 μm and 105.8 μm. Where the crystallinity value of the samples obtained by 73.75% and 77.19%. The addition of potato starch to the sample can enlarge pore diameter, facilitate ion exchange and increase sample resistance during the immersion process using SBF solution.Keywords: potato starch, hydroxyapatite, Simulated Body Fluid, in-vitro test
Kinetika Adsorpsi Ion Logam Cu+2 Menggunakan Tricalcium Phosphate Sebagai Adsorben Siti Chotijah; Ahmad Fadli; Komalasari Komalasari
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 5, No 1 (2018): Wisuda April Tahun 2018
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The methods used for reducing the level of heavy metals have been developed. One of the methods used for reducing the level of Cu metal wastes in waters is the adsorption process. The purpose of this research is to observe the effects of the initial Cu+2 metal ion concentration and the mass of the adsorbent on the capability of tricalcium phosphate (TCP) to adsorb, and also to establish a suitable model of the adsorption kinetics. Add a 500 mL solution of Cu (3 mg/L, 9 mg/L, and 15 mg/L) to tricalcium phosphate (TCP) (1 gram, 2 gram, and 3 gram) in a beaker glass, stirred with a speed of 300 rpm at 30oC. Take the solution of Cu2+ at 0; 30; 1; 1.5; 2; 2.5; 3; and 3.5 minutes, and then analyze the solution of dicentrifuge Cu and Cu by using the Atomic Absorption Spectroscopy (AAS). The research shows that the smaller the concentration of the adsorbent and the bigger the mass of the adsorbent, the bigger the capability of the Cu+2 metal ion to adsorb. The research also obtains the value of the kinetics, with a concentration of 3 mg/L, of 1 gram adsorbent (4.3721 g/mg.min), 2 gram adsorbent (5.4432 g/mg.min), and 3 gram adsorbent (5.4925 g/mg.min). With a concentration of 9 mg/L, 1 gram adsorbent (0.9926 g/mg.min), 2 gram adsorbent (1.1154 g/mg.min), and 3 gram adsorbent (1.4401 g/mg.min). With a concentration of 15 mg/L, 1 gram adsorbent (0.1390 g/mg.min), 2 gram adsorbent (0.2490 g/mg.min), and 3 gram adsorbent (0.4805 g/mg.min). The minimum value of the adsorption kinetics is obtained at 1 gram adsorbent with a concentration of 15 mg/L (0,1390 g/mg.min) and the maximum value of adsorption kinetics constants is obtained at 3 gram adsorbent with a concentration of 3 mg/L (5.4925 g/mg.min).Keyword : kinetic, adsorption, cuprum, tricalciumphosphate (TCP) .
Model Kesetimbangan Adsorpsi Doxorubicin Pada Hidroksiapatit Muhammad Hamdani; Ahmad Fadli; Fajril Akbar
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 5 (2018): Edisi 2 Juli s/d Desember 2018
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains

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Hydroxyapatite has been applied in the biomedical field as drug delivery. The drug will be absorbed onto the hydroxyapatite surface through the adsorption process. The purpose of this study was to determine the effect of initial concentration of doxorubicin (DOX) and the operating temperature on hydroxyapatite adsorption, and to determine the appropriate adsorption equilibrium model. Research began by making a solution of doxorubicin with an initial concentration of 485.83; 661.67; 884.17 mg/L. A 5 mL DOX solution was mixed with 10 mg hydroxyapatite in a beaker glass, then stirred using a magnetic stirrer at 220 rpm at 30, 40, 50 °C for 18 hours. After centrifugation, the concentration of DOX solution in the liquid was tested using UV-Vis spektofotometry. The results showed that the adsorption capacity () increased with increasing initial concentration () DOX. The value of () increased consecutively from 223.86-430.18; 231.59-434.46; 230.48-432.04 mg/g with increasing ofvalue from 485.83-884.17 mg/L at temperature of 30, 40, 50 °C. The highest value of () was obtained at 40 °C, i.e., 231.59-434.46 mg/g. It was found that the Langmuir was an appropriate equilibrium model, where the maximum adsorption capacity () values for each temperature 30, 40, 50 °C are 151.52; 163.93; 181.82 mg/g.Keywords: adsorption, doxorubicin, equilibrium model, hydroxyapatite.
Pembuatan Trikalsium Fosfat Berpori Menggunakan Metode Protein Foaming -Starch Consolidation Dengan Variasi Rasio Bahan Baku Dalam Slurry Dan Temperatur Pengeringan Wan Elsa Novtari Adiani; Ahmad Fadli; Irdoni Irdoni
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 3, No 1 (2016): Wisuda Februari Tahun 2016
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Porous tricalcium phospate has been widely used in the implantation of bone tissue. Protein foaming-consolidation method is a technique for production of porous tricalcium phosphate using egg white as pore creating agent. The purpose of this research was to investigate variation of the ratio of egg white in slurry and drying temperature effects on physical, and chemical of porous TCP by using protein foaming-consolidation method. This research was started by mixing 7 grams of TCP powder, 2 grams of starch, 1,5 grams Darvan 821A, with 5 grams of egg white, 7 grams of egg white and 9 grams of egg white. The slurries were stirred at 150 rpm for 3 hours. Then, the slurries were cast in a cylindrical stainless steel mold and heated at 180°C, 200°C, and 220°C for 1 hour. Subsequently, dried samples were demolded. Next, samples were burned at 600°C for an hour. For the final steps, samples were sintered at 1100°C for 2 hours. Number of egg white and drying temperature increased result in porosity increased and compressive strength of porous tricalcium phospate decreased. This research resulted in porous TCP with 67,6%-78,13% porosity and the compressive strength was 0,14-1,4 MPa.Keyword : compressive strength, egg white, porosity, tricalcium phosphate
Pengaruh Pretreatment Batang Sawit Terhadap Sifat Dan Morfologi Wood Plastic Composite (WPC) Muchlis Ade Putra; Ahmad Fadli; Bahruddin Bahruddin
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 2, No 1 (2015): Wisuda Februari Tahun 2015
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Palm trunk wood is one of solid waste from palm plantations that have not been utilized optimally. This waste can be developed as materials for Wood Plastic Composite (WPC). Extractive substances and hemicellulose fraction of this material may inhibit mixing process between wood filler and matrix, so it takes a pretreatment to eliminate these fraction. Effect of pretreatment on the properties and morphology of the resulting WPC studied in this research. Pretreatment was performed in an autoclave using water and solution of oxalic acid (OA) with concentration 0,05 M and 0,1 M at soaking temperature 1000C and 1400C then held for 5 and 15 minutes. Mixing the filler and matrix with the ratio 30/70, 2% mass paraffin and 5% mass of Maleic Anhydrate Polypropylene (MAPP) was conducted on Internal Mixer Labo Plastomills with temperature and rotor speed conditions 170 0C and 80 rpm respectively. Results of the lignocellulose analysis showed that highest reduction of extractive substances and hemicellulose fraction was 95,94 % and 25,22 %. The best mechanical and physical properties found in the pretreated sample with conditions 0,05 M OA concentration, 140 0C soaking temperature, and 15 minutes soaking time. The tensile strength, flexural strength, and water absorption values was 273,244 kgf/cm2, 427,551 kgf/cm2 and 1,120 %, respectively.Keywords : filler, lignocelluloce, pretreatment, wood plastic composite
Aplikasi Shrinking Core Model Pada Sintesis Hidroksiapatit Menggunakan Metode Hidrotermal Suhu Rendah Nuraina Siregar; Ahmad Fadli; Edy Saputra
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 3, No 2 (2016): Wisuda Oktober Tahun 2016
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Hydroxyapatite (HA) is a ceramic material can be used as bone and dental implants. Hydroxyapatite can be synthesized from calcium oxide (CaO). The purpose of this study was to determine the effect of reaction time and stirring rate on the characteristics of HA using a low temperature hydrothermal method and determine the kinetics model with the approach of shrinking core models. There are 3 models that are used; diffusion through the film layers, diffusion through the layer result (HA), and chemical reactions. The first procedure was weighing 36.9 of grams NH4H2PO4 and dissolved in 600 ml of aquadest are then added 30 of grams CaO at a temperature of 90 °C and reaction time with variation 5, 30, 60, 90, and 150 minutes. The mixture was stirred rate of 100, 200, 300 rpm until paste formed. The paste was dried in an oven at a temperature of 110oC for 15 hours and calcined at a temperature of 900oC for 1 hour. XRD diffraction results shows HA with pure content of 95% and SEM result shows morphology of HA was like agglomerate. The best kinetics model showed synthesis of HA is model 2 with equation:It was named “Diffusion Through the Layer Results (HA)” with the smallest percentage error of 4,3%.Keywords: CaO, hydroxyapatite, hydrothermal, model kinetics, shrinking core
Kinetika Reaksi Deproteinasi Limbah Udang Ebi Pada Isolasi Kitin Ridho Wijaya; Ahmad Fadli; Idral Amri
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 5, No 1 (2018): Wisuda April Tahun 2018
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Chitin is a biopolymer and can be synthesized from ebi shrimp waste through deproteination and demineralization processes. The purpose of this study was to determine the kinetics of deproteination reaction in chitin isolate with variable reaction temperature and stirring rate. The study began by reacting shrimp waste powder with 3.5% NaOH solution using a ratio of 1:10 at 75 ° C, 85 ° C and 95 ° C and 200 stirring speeds, and 250 rpm in a glass beaker equipped with stirrer. Samples were taken every 10, 20, 30, 50, 70, 90, 110 and 120 minutes as much as 40 mL, then washed until the pH was neutral and the sample filtered. The shrimp powder produced was analyzed using titration method of formol to know the protein content contained in the sample. The results showed that the reaction kinetics follows the pseudo first order equation. The higher the temperature and the speed of stirring given to the deproteination process the greater the concentration produced. The reaction speed constant at 75°C, 85°C and 95°C with 200 rpm stirring speed was obtained at k = 0.0098 min-1 to 0.0217 min-1. While at 250 rpm stirring speed k = 0.0113 min-1 to 0.0255 min-1. The optimal condition available in this study is 95oC with 250 rpm stirring speed so that it produces protein from 14.08% to 0.87%.Key words : Deproteination, chitin, reaction kinetics, ebi shrimp waste, FTIR analysis.
Aplikasi Shrinking Core Model Pada Sintesis Hidroksiapatit Dari Kulit Kerang Darah (Anadara Granosa) Dengan Menggunakan Metode Hidrotermal Suhu Rendah Ervina Ervina; Ahmad Fadli; Idral Amri
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 3, No 2 (2016): Wisuda Oktober Tahun 2016
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Hydroxyapatite (HA) is a ceramic material that can be used as bone and dental implants. Hydroxyapatite can be synthesized from the cockle shell (Anadara granosa). The purpose of this study was to determine the effect of time and stirring rate on the characteristics of HA using a low temperature hydrothermal method as well as decide of the kinetics model with the approach of shrinking core models. There are 3 models that are used, namely diffusion through the liquid film control, diffusion through the layer results (HA) control, and chemical reaction control. Research procedures initiated by the reaction of 36.9 g NH4H2PO4 dissolved in 600 mL of water were then added as much as 39.37 g CaO at stirring rate of 100 rpm, 200 rpm, 300 rpm and reaction time of 5 minutes to 150 minutes. The mixture was reacted at a temperature of 90˚C to form a paste. The paste was dried in an oven at 120˚C for 12 hours and calcined at a temperature of 900˚C for 1 hour. The results showed that the product formed is 95% fraction massa of HA. Kinetics model that describes the events of the synthesis of HA for belong to model 2, i.e diffusion through the layer results (HA) control with the smallest error percentage of 16.15 % with the formula:Keywords: cockle shell, hydrothermal, hydroxiapatite, kinetics model, shrinking core model
Pengaruh Waktu Tinggal Hidrolik Terhadap Efisiensi Penyisihan Padatan Dalam Limbah Cair Industri Sagu Dengan Menggunakan Bioreaktor Hibrid Anaerob Dua Tahap Riki Rahmadhan; Adrianto Ahmad; Ahmad Fadli
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 3, No 1 (2016): Wisuda Februari Tahun 2016
Publisher : Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains

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Sagoo industries was produced wastewater with high concentration of solids that potentially causes environment problem’s. One way to got lower concentration of solids with making use two-stage hybrid anaerobic bioreactor’s with stone media. The purpose of this study was to remove and determine the highest solids removal efficiency in wastewater treatment sagoo. Twosatge hybrid anaerobic bioreactor in continuous process with working volumes 10 L was used instage I and 20 L was used in stage II. The output from stage I was used as the input for stage II. The two-stage reactor was operated at a hydraulic retention time that varied from 2 days in stage I and 3,5 and 7 days in stage II. The results showed that highest of solids removal efficiency was obtained in the operation of hydraulic retention time 7 days. The value of TS(81,03%), TVS (72,92%), TSS (71,13%) and VSS (68,63%). Two-stage hybrid anaerobic bioreactors system exactly effective and efficient within to got lower concentration of solids in wastewater of sagoo industry’s.Keywords: anaerobic, continuous, hybrid bioreactor, hydraulic retention time, solid concentrations, two-stage, wastewater of sagoo industry.
Pembuatan Biodiesel Dari Minyak Nyamplung Dengan Menggunakan Katalis Basa Na2SiO3/Fe3O4 Nissa Aqhilla; Edy Saputra; Ahmad Fadli
Jurnal Online Mahasiswa (JOM) Bidang Teknik dan Sains Vol 4, No 2 (2017): Wisuda Oktober Tahun 2017
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Biodiesel is an alternative energy to replace fossil fuels. It can be made by transesterification process of vegetable oils. During the process of making biodiesel usually was used NaOH or KOH as homogeneous catalyst which has the disadvantage the formation of side products such as soaps and complexity of the separation of catalyst. Therefore, in this study Na2SiO3/Fe3O4 catalyst is used. The independent variables of this research are mol ratio of CIO and methanol 1:6, 1:8, 1:10 and loading catalyst Na2SiO3/Fe3O4 1%, 2%, 3%. Density (40°C) of biodiesel is 876,18 kg/m3, kinematic viscosity (40°C) is 4,63 cSt, flash point is 107°C, and acid value is 0,49 mg-KOH/g-biodiesel.Keywords: Biodiesel, Catalyst, CIO, Transesterification
Co-Authors Abdul Kohar Abdul Malik K.A Abdul Rasyid Achmad Noerkhaerin Putra Adam Samsudin Noor Ade Pratama Adela Shofia Addabsi Adha Widoni Adi Maulana Putra Adi Mulyadi Putra Adrianto Ahmad Aep Saefullah Afrila Afrila Agung Prabowo Agung Prabowo Agus Susanto Agya Mutia Alifta Ahmad Aguswin Ahmad Fadhil Nugroho Ahmad Riadi S Hasibuan Ahmad Zaki Akhmad Akhmad Akhmad Akromusyuhada Alfarisi, Cory Dian Allailus Syah Safara Aman aman Amun Amri Andi Risfan Rizaldi Annisa Aprilya Putri Annisa Rahmat Ap’aluddin Ari Aditia Sukma Sukma Arifin Setiabudi Arisky Rahmatulloh Arosyidin Arosyidin Aulia Permatasari Bahruddin Benny Ahmadi Bima Wandika Putra Cahyo Dwi Rachmadi Calvin Prasetyo Chaniago, Sabaruddin Charismayani Charismayani Chorina Ika Ristanti Damayanti, Elok Debora Tambunan Deni Astika Derry Hanriansyah Pratama Deska Deska Devia Febrina Dewi Indah Pratiwi Dewi Rafiah Pakpahan Dhamala Shobita Chandra Dhanang Hayuningwang Dingot Hamonangan Sitanggang Dion Julio Iskandar Dovy Reyandi Drastinawati Drastinawati Dwi Yerlis Rahmi Edy Saputra Effendi, Ihsan Elvira Sitna Hajar Emizatul Aini Ervina Ervina Esty Octiana Sari Fadhil Mubarak Fajril Akbar Fernando Susilo Fisy Amalia Gading Bagus Mahardika Gede Indra Ludy Wirata Gunawan Atmaja Halim Wijaya Heni Sugesti Herry Novriansyah I Wayan Sudiarta Idral Amri Ika Agustina Ika Karina Ika Puspa Satriany Ilham Habib Indah Fitriani Indra Yasri Indrawan Indrawan Ines Indriyani Irdoni HS Irdoni Irdoni Irwan Ahussalim Jabosar Ronggur Hamonangan Panjaitan Jannatin Ardhuha Jayaun Jayaun Jenial S Jenni Kristina Br Panjaitan Jessica Andre Julharmito Julharmito Junaidi Junaidi Kania Farida Komalasari Komalasari LALU RUDYAT TELLY SAVALAS Lathifah Cahyani P3 Lia Yuningsih Lilis Suriani Luci Octaria M Satria Haruda M. Ferdinansyah M. Zamroni Mahendra Aswit Sandra Barata Manda Dwipayani Bhastary Marlinda Martin Maya Andiriani MAYANG SARI Mega Safana Mega Sanjaya Melda Helena S Miftah Anugrah Mochamad Reizal Ath Thariq Moh. Tahang Mona Lisa Muchlis Ade Putra Muh Irwan Muhamad Hendri Diarta Muhamamad Rizky Zuriadi Muhammad Hamdani Mustika Canra MUTIARANI MUTIARANI Nanda Nabila Maharani Nasib Nisa Mulya Nissa Aqhilla Novika Sri Wardani Novirsari, Emma Nuraina Siregar Nurjamilah Nursyaniati Nursyaniati Nurul Afifah Ongky Alexander Opik Hidayat Abdul Latif Padil Pancasila Putri Peter Peter Puji Rahayu Purnama Sari Putri Arini Putri Julia Maemum Putri Rahmadani Rahmad Rasyidin Ramadani Pardian Ramadhana Eka Rani Handayani Rathesa Najela Ratih Amelia Rawdatul Fadila Reny Novianti Ridho Hafizh Maulana Ridho Wijaya Riki Rahmadhan Riko Ervil Rio Andika Rizky Gimnastiar Robin Roni Juliansyah Rozanna Sri Irianty Rusydy ' Sai Vinodhini Samsoni Samsoni Septiana Veronika S Septianing Tyas K Silvia Reni Renti Silvia Reni Yenti Silvia Reni Yenty Sintia Siska Priscillia Aledya Siti Chotijah Siti Nurkhaliza Sri Murda Niati Subkhan Maulana Sunarno Sunarno Syarifuddin Oko Syelvia Renni Yenti Thomson Simanjuntak Thufail Mujaddid Al-Qoyim Tina Linda Toni Ardi Ulfa Dwiyanti Ulfah Naida Marbun Wan Elsa Novtari Adiani Wasty Rusjaya Wilda Zakiah Wiriyan Jordy Wyda N Saragi Yelmida Azis Yesi Afriani Yopy Ratna Dewanti Yuli S Yunus Olivia Novanto Zubair Arza Zuchra Helwani Zulkarnain Lubis Zultiniar Zultiniar