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Andy Andy
Pendidikan Bahasa Inggris, Fakultas Bahasa Dan Sastra, Universitas Kanjuruhan Malang
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Journal : Universa Medicina

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Blood cell count is not a significant predictor of survival in bladder cancer after radical cystectomy Andy, Andy; Prapiska, Fauriski Febrian; Siregar, Ginanda Putra; Warli, Syah Mirsya; Sihombing, Bungaran
Universa Medicina Vol. 40 No. 2 (2021)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2021.v40.151-159

Abstract

BackgroundRadical cystectomy (RC) is the gold standard treatment for muscle-invasive bladder carcinoma. A predictive factor is needed for the aggressive approach as it could lead to overtreatment. Elevated blood cell count (BCC) markers are reported to have a significant association with poor outcomes in several types of malignancy. Neutrophil-to-lymphocyte-ratio (NLR) and platelet-to-lymphocyte ratio (PLR) are well-known inexpensive and effective representative markers of inflammatory conditions. This study aimed to determine the BCC as a predictive factor of overall survival (OS) in patients with bladder carcinoma (BC) after RC. MethodsA retrospective cohort study was conducted involving 26 patients who had undergone RC. The demographic characteristics and BCC markers such as hemoglobin (Hb). NLR, PLR and lymphocyte/monocyte ratio (LMR) were collected. The patients were categorized based on the BCC marker value (³ median and < median). Kaplan–Meier survival analysis was done to determine overall survival (OS) on BCC markers. The association between patient demographics and one-year survival was also determined using Mantel-Cox (Log-rank) method. ResultsAmong the 26 patients, the mean age was 55.6 ± 12.9 years. On univariate analysis, none of the demographic characteristics was found to be a significant predictor of one-year and overall survival (p>0.05). Hemoglobin, NLR, PLR and LMR were not significant predictors of one-year survival and OS (p>0.05). ConclusionsThe BCC was not a significant predictive factor of survival in patients with bladder cancer after radical cystectomy.
Co-Authors Aditya Pratama Adrian Hidayat, Adrian Agus Maringan Siahaan Agus Sholeh Agus Suryanto Agustin, Viona Alnandez, Leo Amelia Amelia Antonio, Ferdi Aparianto, Aparianto Arif Budi Prasetya Aritonang, Jonsfir Daus Armeliza, Diah Asmiraty, Asmiraty ATI SUMIATI, ATI Aulyani, Tutik Lusyta Aurelia, Clara Aviva Cornita Ayu Liskinasih Azhar, M Candyce, Candyce Chandra Chandra Chandra Christina Christina Damaiyanti, D.R.R. Dandi, Dandi Daud, Ilzar David David Derrick, Lionel Didik Aryanto Didik Aryanto Dita Puruwita, Dita edi edi F.X Pudjo Fauriski Febrian Prapiska, Fauriski Febrian Fauzan, Rizky Febrianty, Levina Felicia Padma Susilo Ginanda Putra Siregar, Ginanda Putra Henryanto Wijaya Herawati, Siane Herijawati, Etty Hernawan, Eso Huang, Stephen Iman Kalis, Maria Chirstiana Iman, M. Febri Shahrul Iwan Asmadi Jeslin, Jeslin Jesslyn, Jesslyn Joni Joni Joycelyn, Joycelyn juliadarma, minggusta Juliandy, Carles Julyance, Zoey Kelvin Kelvin Khaerunnisa Khaerunnisa, Khaerunnisa Kirtileka, Saddha Budianto Kosasih, Jefry Kusnawan, Agus Kusuma, Satria Budi Lasim Muzammil Laulita, Nasar Buntu Lestari, Sri Indah Lili Yanti, Lili Lilia, Wirda Lily Purwianti Lim, Vincent Lubis, Yeti Meliany Luthfi Fatullah, Andi M. Irfani Hendri Magdalena, Fanny Maharani, Diva Mardhyanti, Mardhyanti MARIA BINTANG Maria Cholifah Miksen M. Sangkek Milliard, Mallaury Moksidy, Jevany Claudia Morgan, Christopher Elihu Billy Mufidah, Chusnanik Muhammad Suharto Muhammad Yusuf Muzammil, Lasim Neni Triani, Susan Nisa, Akramun Novana, Cindy Nuraeni Nuraeni Paerin, Paerin Pieter Octaviandy, Pieter Polii, Nanvy Jenix Dean Poppy Amalia, Poppy Pratama, Ayang Puji Yuniarti Pujiarti, Pujiarti Purwanti, Angel Putri, Jane Lovita Putri, Rossje V. Surya Raditya, I Made Guna Rakhmat, Rakhmat Rinoa, Livvy Riswandi Riswandi Rizky, Muhammad Dipo Agung Robet Robet Rose, Felicia Diana Rusfandi Rusfandi Sanjaya, Enrico Sari, Amanda Novita Sari, Wanda Pramitha Sartika Sartika Satrianto, Heri Satriya Miharja Selfiyan, Selfiyan Selvi Selvi Siahaan, Agus Sihaloho, Marlinda Latare Sihombing, Bungaran Silaban, Berlin Silaswara, Diana Sitawati Sitawati Situmeang, Hendrik Hagai Susanto Wibowo, Susanto Sutandi, Sutandi Syalsabila, Anis Teguh Sulistyo Terang kita Perangin Angin, Johanes Toto Himawan Tursini, Umi Vanomy, Afrianti Warangkiran, Eklesia Dian Milenia Warli, Syah Mirsya widjaja, karen Wijaya, Robby Wilson Wilson Wilson Winaldo, Vincent Winestia, Winestia Wiwik Handayani Wulandari, Bayu Zahra Zahra Zahra, Siti Fatimah