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All Journal HAYATI Journal of Biosciences Jurnal Keperawatan Indonesia Bionatura Jurnal Natur Indonesia Jurnal Sains dan Teknologi Farmasi Jurnal Riset Kimia Alchemy Jurnal Penelitian Kimia JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE INDONESIAN JOURNAL OF PHARMACY Jurnal Ilmiah Universitas Batanghari Jambi Jurnal Kesehatan Medika Saintika Indonesian Journal of Chemistry Indonesian Food Science and TechnologyJournal Jurnal Keperawatan Muhammadiyah JSFK (Jurnal Sains Farmasi & Klinis) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun JFIOnline Jurnal Ilmu Kefarmasian Indonesia Jurnal Farmasi Higea Viva Medika: Jurnal Kesehatan, Kebidanan dan Keperawatan Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Pharmaceutical Sciences and Research (PSR) Jurnal Ilmu Kedokteran dan Kesehatan Indonesia Borneo Journal of Pharmacy Journal of Tropical Pharmacy and Chemistry Jurnal Ilmu Kedokteran dan Kesehatan Indonesia

Dachriyanus

Faculty Of Pharmacy, Andalas University, Kampus Limau Manis, Padang -25163 PO. Box 143, Indonesia

Author-ID : 248553

Agriculture, Biological Sciences & Forestry Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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ANTIOXIDANT ACTIVITY OF LEAF EXTRACT FROM SIDA SUBCORDATA SPAN Rahma Yulia; Dachriyanus Dachriyanus; Amri Bachtiar
JOURNAL OF HEALTHCARE TECHNOLOGY AND MEDICINE Vol 1, No 2 (2015): Oktober 2015
Publisher : Universitas Ubudiyah Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33143/jhtm.v1i2.69

This Study has tested the antioxidant activity of the extracts from Sida subcordata Span. Testing is done with antioxidant activity using DPPH method provides. Testing of antioxidant activity in vitro with spectrophotometric methods based on absorbance measurements radical DPPH (1,1-diphenylpicrylhydrazyl). All the extracts Showed radical scavenging activity. The ethyl acetate and methanol extracts were the most Appropriate as sources of antioxidant compounds as shown by Reviews their inhibition percentage (IP) values. Percentage inhibitor to extract ethyl acetate and methanol extract respectively 76.16% and 79.28% at a concentration of 1 mg / ml to 0.05 mM DPPH. while the results of the testing activities of antioxidant compounds y pure ethyl acetate extract fraction showed a smaller percentage inhibitor that is equal to 30% at the same concentration. Keyword - Sida subcordata Span, Malvaceae, Antioxidant, Alkaloid

DEVELOPMENT AND VALIDATION OF A HPLC METHOD FOR DETERMINATION AND QUANTIFICATION OF RUBRAXANTHONE IN STEM BARK EXTRACT OF MANGOSTEEN Meri Susanti; Dwisesaria Irma Lena; Dachriyanus Dachriyanus
Indonesian Journal of Pharmacy Vol 25 No 4, 2014
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

Rubraxanthone is one of antibacterial and antioxidant compound which is isolated from stem bark of mangosteen (Garcinia mangostana Linn.). The precise method for analysis of plant constituents is normally a reverse-phase high performance liquid chromatographic (RP-HPLC). Development and validation of a RP-HPLC method for chromatographic separation was carried out on a reversed-phase column Shimadzu ® Shimp-pack VP – ODS (4.6x250mm) using an isocratic mobile phase of 0.4% formic acid - acetonitrile at a flow rate 1mL min-1, and detection was with a UV detector. The linearity of the proposed method was found in the range of 2.5-25μg/mL-1 with regression coefficient 0.999. Intraday precision studies showed the relative standard deviation ≤1.58% and inter-day ≤3.20%. Accuracy of the method was determined by a recovery study conducted at 3 different levels, and the average recovery was 102.18%. The Limit of Detection Limit of Quantitation (LOQ) and were 0.47 and 1.56μg/mL-1.The contents of rubraxanthon in the crude was 0.23±0.07%w/w.

Characterization antibacterial constituent from Ficus deltoideusJack leaves Suryati .; Hazli Nurdin; Dachriyanus .; Md Nordin Hj Lajis
Indonesian Journal of Pharmacy Vol 21 No 2, 2010
Publisher : Faculty of Pharmacy Universitas Gadjah Mada, Yogyakarta, Skip Utara, 55281, Indonesia

An antibacterial constituent, has been isolated from Ficus deltoideus Jack leaves. Based on spectroscopic data (IR, 1H-NMR, 13 C NMR 1D and 2D and MS), the structure of this compound was identified as Olean-12en-3β-ol, (β-amyrin), C30H50O. This compound showed antibacterial activities against E. coli, B. subtilis and S. aureus. The minimum inhibition concentration (MIC) agains E. coli, B. subtilisand S. aureusare 230, 380 and 460 (µg/mL) respectively.Key words: Antibacterial activity,Ficus deltoideusJack, β-amyrin

Dukungan Keluarga Memengaruhi Kepatuhan Pasien Hipertensi Fitra Yeni; Miftahul Husna; Dachriyanus Dachriyanus
Jurnal Keperawatan Indonesia Vol 19, No 3 (2016): November
Publisher : Faculty of Nursing Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.7454/jki.v19i3.471

Hipertensi adalah keadaan meningkatnya tekanan darah sistolik lebih besar dari 140 mmHg dan atau diastolik lebih besar dari 90 mmHg. Keefektifan terapi pasien hipertensi ditentukan oleh kepatuhan, dan dukungan keluarga dapat menjadi faktor yang sangat berpengaruh. Penelitian ini bertujuan untuk membuktikan seberapa besar hubungan dukungan keluarga dengan kepatuhan pada pasien hipertensi. Ini merupakan penelitan deskriptif korelatif dengan pendekatan cross sectional dan jumlah sampel sebanyak 59 orang. Pengumpulan data dilakukan di Puskesmas Padang Pasir Kota Padang tanggal 4-30 April 2013 dengan menggunakan kuesioner. Analisa data penelitian terdiri dari analisa univariat yang menggambarkan dukungan keluarga dan kepatuhan responden sedangkan analisa bivariat menggunakan uji korelasi Rank Spearman (r). Hasil penelitian menunjukkan sebanyak 54% responden mendapatkan dukungan keluarga dengan kategori sedang dan 59 % responden mempunyai kepatuhan dengan kategori sedang. Hasil uji statistik didapatkan nilai (r) = 0,786. Disimpulkan bahwa dukungan keluarga mempunyai hubungan sangat kuat dengan kepatuhan dan terdapat hubungan searah, sehingga semakin tinggi dukungan keluarga maka semakin tinggi kepatuhan. Dukungan keluarga berkontribusi sebesar 61,8% terhadap kepatuhan. Keluarga harus lebih memperhatikan pemberian dukungan informasional terhadap pasien hipertensi. Abstract Family Support Affect Patient Compliance with Hypertension. Hypertension is a state of increased systolic blood pressure greater than 140 mmHg and or diastolic greater than 90 mmHg. The effectiveness of treatment is determined by the compliance of hypertensive patients, and family support can be a very influential factor. This study aims to determine the relationship of family support with adherence in hypertensive patients. The study was a descriptive correlative with cross sectional approach and sample are 59 people. Data collection was conducted at Puskesmas Padang Pasir from 4 to 30 April 2013, collected using questionnaires. Data analysis consisted of univariate analysis that describes the family support and adherence respondents then bivariate analysis using Rank Spearman (r) correlation test. The results showed 54% of respondents have family support with medium category and 59% respondents have compliance with medium category. Statistical test results obtained values (r) = 0.786. Concluded that family support has a very strong relationship with compliance and there is a direct relationship, so higher family support make impact higher compliance. Family support accounted for 61.8% of compliance. Family should pay more attention to providing informational support to patients with hypertension Keywords: adherence, hypertension, family support

Edukasi Obat pada Masyarakat Bebasis Ibu Rumah Tangga Menggunakan Model Permainan Pintar dengan Obat (Piano) Syofyan Syofyan; Dachriyanus Dachriyanus; Masrul Masrul; Rosfita Rasyid; Erizal Erizal; Hadi Ihsan; Agung Tri Sasongko
Warta Pengabdian Andalas Vol 26 No 3 (2019)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar

Many people's behavior in using medicines is still incorrect. The intended behavior is starting from how to get, use, store and dispose of drugs. This is inseparable from the factor of low knowledge about medicines. Community service activities aim to provide appropriate education to the community related to the above drug problems. As partners are the PKK Team of Talago Sariak Village, Pariaman City is a housewife. Selection of housewives as targets because housewives are usually the most responsible community groups in terms of managing medicines in the household or family. The activity method is in the form of using a game model that is Smart with medicines (PIANO) and questionnaires in the form of pre-test and post-test. The results showed that there was an increase in people's knowledge and attitudes about medicine, where the percentage of the average score of knowledge increased from 50.6% to 69.4%. Likewise with attitudes from 67.36% to 73.46%. From these results, it can be concluded that education about medicines using the PIANO game model can be a pretty good educational model in helping to improve people's knowledge and attitudes about medicine.

Studi Hubungan Struktur dan Aktivitas Senyawa Antioksidan dari Kulit Batang Kandis Gajah (Garcinia griffithii T. Anders) ELFITA ELFITA; DACHRIYANUS DACHRIYANUS; SUPRIYATNA SUPRIYATNA; HUSEIN H. BAHTI
JURNAL ILMU KEFARMASIAN INDONESIA Vol 9 No 1 (2011): JIFI
Publisher : Fakultas Farmasi Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1347.253 KB)

Four xanthones and two benzophenones from the stem bark of kandis gajah (Garcinia griffithii) by extraction and chromatographic methods have been isolated. The six compounds were determined as: 1,7-dihydroxyxanthone (1), 1,6,7-trihydroxyxanthone (2), 1,6-dihydroxy-3-methoxy-4,7-di-(3-methylbut-2-enyl)xanthone (3), 1,5-dihydroxy-3,6-di-methoxy-2,7-di-(-3-methylbut-2-enyl)xanthone (4), guttipherone I (5), and isoxanthochymol (6). All of the isolated compounds were submitted to antioxidant activity assay using three methods: (i) free radical scavenging method, (ii) xanthine-xanthine oxidase (XO) method, and (iii) nitroblue tetrazolium xanthine oxidase (NBT/ XO). Guttipherone I (5) and isoxanthochymol (6) have strong antioxidant activity (IC50 ≤10.2 µg/mL), 1,6,7-trihydroxyxanthone (2) and 1,6-dihydroxy-3-methoxy-4,7-di-(3-methylbut-2-enyl)xanthone (3) as active compounds (IC50 ≤ 100 µg/mL), while 1,7-dihydroxyxanthone (1) and 1,5-dihydroxy-3,6-dimethoxy-2,7-di-(3-methylbut-2-enyl)xanthone (4) were inactive (IC50 > 100 µg/mL). Base on the data, antioxidant activity of isolated compounds was inhuenced by dihydroxyl groups at ortho position, number of hydroxyl group, and hydroxyl group at para position to C carbonyl at heterocyclic.

Uji Aktivitas Antimikroba Ekstrak Metanol Daun Tabat Barito ( Ficus deltoidea Jack) Krisyanella Krisyanella; Meri Ardianti; Dachriyanus Dachriyanus
Jurnal Farmasi Higea Vol 1, No 1 (2009)
Publisher : STIFARM Padang

An antimicrobial activity studies from methanol extract of the leaves Tabat Barito (Ficus deltoidea Jack) to some bacterias and fungis with diffusion method and determination of Minimum Inhibitory Consentration (MIC) by using dilution method have been done. From antimicrobial activity test by using diffusion method show that methanol extract of the leaves Tabat Barito (Ficus deltoidea Jack) can inhibit the growth of bacterias and fungis. The MIC for staphylococcus aureus is 1%, for staphylococcus epidermis is 0.7%, for staphylococcus aeruginosa is 0.8%, and for eschericha coli is 0.7%.

Penentuan Kadar Fenolat Total, Uji Aktivitas Antioksidan dan Antibakteri dari Ekstrak dan Fraksi Kulit Batang Bintangor (Calophyllum soulattri Burm. F) Elidahanum Husni; Dachriyanus Dachriyanus; Veny Wahyu Saputri
Jurnal Sains Farmasi & Klinis Vol 7, No 1 (2020): J Sains Farm Klin 7(1), April 2020
Publisher : Fakultas Farmasi Universitas Andalas

Bintangor (Calophyllum soulatri Burm. F) merupakan tumbuhan dari familia Clusiaceae. Beberapa bagian dari tumbuhan ini seperti kulit batangnya telah lama digunakan sebagai obat tradisional. Penelitian ini bertujuan untuk mengetahui kadar fenolat total, aktivitas antioksidan dan antibakteri dari kulit batang bintangor dalam bentuk ekstrak dan fraksi. Ekstrak kulit batang bintangor dibuat dengan teknik maserasi dengna pelarut etanol, sedangkan fraksinasi dilakukan dengan pelarut n-heksan, etil asetat dan butanol. Kadar fenolat total dari ekstrak dan fraksi ditentukan menggunakan metode Folin-Ciaocalteau. Aktivitas antioksidan ditentukan dengan metode Ferric Reducing Antioxidan Power, sedangkan aktivitas antibakteri dievaluasi dengan metode difusi agar terhadap bakteri patogen. Hasil penelitian menunjukkan bahwa kadar fenolat total tertinggi diperoleh dari ekstrak etanol (60,481 g/100 g), demikian juga dengan aktivitas antioksidan tertinggi (4,29 mmol Fe(II)/100 g). Aktivitas antibakteri paling baik diperlihatkan oleh ekstrak etanol dengan konsentrasi hambat minimum 0,8%, menghasilkan diameter hambat 6,96 mm, diikuti oleh fraksi n-heksan (konsentrasi 0,9%, menghasilkan diameter hambat 6,63 mm), fraksi etil asetat (konsentrasi 0,625%, menghasilkan diameter hambat 6,28 mm), dan fraksi butanol (konsentrasi 0,5%, menghasilkan diameter hambat 6,03 mm).

Aktivitas Sitotoksik Ekstrak Etil Asetat Daun Tampa Badak (Voacanga foetida (Bl.)K.Schum) pada Kanker Kolon HTB-38 Adriani susanty; Dachriyanus Dachriyanus; Yanwirasti Yanwirasti; Fatma Sri Wahyuni; Haiyul Fadhli; Pedro Anugrah Aswan
Jurnal Sains Farmasi & Klinis Vol 5, No 2 (2018): J Sains Farm Klin 5(2), Agustus 2018
Publisher : Fakultas Farmasi Universitas Andalas

Kanker kolon merupakan penyakit yang ditandai oleh perkembangan sel yang tidak terkendali di lapisan epitel pada usus besar. Salah satu tumbuhan yang memiliki aktivitas sebagai antikanker yaitu tumbuhan tampa badak (Voacanga foetida (Bl.) K.Schum). Tumbuhan tampa badak adalah keluarga apocynaceae yang memiliki aktivitas antikanker terhadap sel kanker darah (L1210 dan K256), sel kanker paru (A549) dan sel kanker serviks (HeLa). Penelitian ini bertujuan untuk mengetahui efek sitotoksik ekstrak etil asetat daun tampa badak terhadap sel kanker kolon HTB-38. Metode yang digunakan pada pengujian ini adalah metode MTT Assay pada waktu 24, 48 dan 72 jam. Parameter yang digunakan adalah IC50. Hasil penelitian menujukkan bahwa nilai IC50 ekstrak etil asetat daun tampa badak terhadap sel kanker kolon HTB-38 pada waktu 24, 48 dan 72 jam masing-masing sebesar 0,0287, 0,0776 dan 0.0415 μg/mL. Hasil penelitian ini menunujukkan bahwa ekstrak etil asetat daun tampa badak mempunyai efek sitotoksik kuat terhadap sel kanker kolon HTB-38. Hasil uji ANOVA menyatakan bahwa terdapat perbedaan persen viabilitas antara konsentrasi 0,1 μg/mL, konsentrasi 0,5 μg/mL dan konsentrasi 1 μg/mL (p<0,05) tetapi lama waktu inkubasi tidak memiliki pengaruh terhadap nilai persen viabilitas (p>0,05).

HUBUNGAN FAKTOR INDIVIDU, ORGANISAI DAN PSIKOLOGIS PERAWAT DENGAN PENERAPAN PATIENT SAFETY DI RUANG RAWAT INAP RSUD SOLOK Dian Dwiana Maydinar; Dachriyanus Dachriyanus; Vetty Priscilla
Jurnal Kesehatan Medika Saintika Vol 12, No 2 (2021): Desember 2021
Publisher : Stikes Syedza Saintika Padang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30633/jkms.v12i2.1325

Keselamatan pasien merupakan sistem pemberian asuhan yang aman bagi pasien di rumah sakit. Pelayanan asuhan keperawatan yang berkualitas merupakan perilaku perawat dalam penerapan pedoman patient safety. Hasil survey dilakukan masih ditemukannya perwat pelaksana belum menerapkan keselamatan pasien. Tujuan penelitian ini adalah mengidentifikasi hubungan antara faktor individu, organisasi dan faktor psikologis perawat dengan kepatuhan dalam menerapkan patient safety di RSUD Solok tahun 2016. Desain yang digunakan dalam penelitian ini adalah penelitian korelasi deskriptif (descriptive corelational) dengan menggunakan pendekatan cross sectional. Populasi dalam penelitian ini adalah seluruh perawat pelaksana yang berada di rawat Inap RSUD Solok sebanyak 147 orang dengan jumlah sampel 109 perawat. Teknik pengumpulan data dengan menyebarkan kuesioner pada masing-masing ruang rawat inap. Analisis data dengan uji chi-square. Hasil penelitian didapatkan faktor individu (usia sebagian besar 20-40 tahun, masa kerja sebagian besar ≥ 5 tahun, tingkat pendidikan sebagain besar D3 Keperawatan) ada hubungan dengan penerapan pasient safety dengan p value (0.004),(0.005),(0.004). faktor organisasi (kepemimpinan, imbalan, struktur organisasi, desain pekerjaan) ada hubungan dengan penerapan pasien safety dengan p value (0.000). faktor psikologis (sikap dan motivasi) ada hubungan dengan penerapan pasien safety dengan nilai p value (0.034), (0.000). Faktor yang paling berhubungan adalah desain pekerjaan. Saran bagi RSUD Solok untuk lebih meningkatkan pemberian reward, pelatihan dan motivasi pada perawat dalam penerapan pasien safety di ruang rawat inap.Kata kunci : faktor individu, organisasi, psikologis, panerapan pasien safety

Co-Authors ', Darwati ', Supriyatna . Almahdy . Ellyza . Yanwirasti A. Manaf Ali AA Sudharmawan, AA Abd. Rasyid Syamsuri Abdul Rohman Abu Bakar, Nor Kartini Adriani Susanty Agung Tri Sasongko Alimin, Nur Almahdy A Almahdy, . Amella Gusty Amri Bachtiar Andayani, Regina Andryani, Putu Cisya Aprilya Sri Rachmayanti Darwati - Dewi, Citra Kartika Dian Dwiana Maydinar Dian Handayani Dian Sanita Putri Dira Dira Dira Hefni Ditya Kesumaningrum Dwisesaria Irma Lena Eka Roza Wijaya Ekaprasada, M. Taufik Elfita Elfita Elfita Elfita Elfita Elfita Elfita Elidahanum Husni Ellis Mawarni Elyunaida, Elyunaida Erizal Erizal Faleh Setia Budi Fatma Sri Wahyuni Fitra Yeni Gusty, Amella Hadi Ihsan Hadi Nasbey Haiyul Fadhli Harmawati Harmawati Hazli Nurdin Hazli Nurdin Hazli Nurdin Hazli Nurdin Henny Lucida Hj. Lajisc, Nordin Hj. Lajisc, Nordin Husein Hernadi Bahti Husen H Bahti Husen H. Bahti Husen H. Bahti - I Gusti Bagus Wiksuana Ihsan Ikhtiarudin Jufri Al Fajri Kamal Rullah Kesumaningrum, Ditya Krisyanella Krisyanella Leni Merdawati Lusianti, Mittha Lusianti, Mittha M. Taufik Ekaprasada M. Taufik Ekaprasada M. V. Sargent Madyawati Latief Magdazaleni, Magdazaleni Maisa, Esthika Ariany Masrul Md Nordin Hj Lajis Md Nordin Hj Lajis Meri Ardianti Meri Susanti Meri Susanti Miftahul Husna Mira Febrina Muharni Muharni Muharni Muharni Muharni Muharni N. H. Ladjis Nancy Dewi Yuliana Netty Suhatri Nilda Lely Nisa, Tadzkia Nordin Lajis Novi Safitri Noviyandi Sayuti Nurdin, Hazli Nurdin, Hazli Nurdina Putri Pedro Anugrah Aswan Putra, Deddy Prima Putra, Deddy Prima Rahma Yulia Rahmat, Rosita Dewi Rahmat, Rosita Dewi Regina Handayani Handayani, Regina Handayani Rizal Fahmi Rob W.M van Soest Rosfita Rasyid Rustini Rustini Salman - Sanusi Ibrahim Saputri, Veny Wahyu Sartika, Zikra Sartika, Zikra Saufitri, Dian Saufitri, Dian Sekar, Andisyah Putri Shinta Sari Dewi Sinata, Novia Sofia, Sri Esky St. Mursyidah Suhaera Suhaera Suhatri Suhatri Supriyatna - Supriyatna Soetardjo Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Supriyatna Surya Dharma Suryati . Suryati Suryati Suryati Suryati Suryati Suryati Suryati Suryati Suryatir - Syofyan Syofyan Tadzkia Nisa Titen Yasril Veny Wahyu Saputri Vetty Priscilla Wijaya, Eka Roza Yanwirasti Yanwirasti Yanwirasti Yanwirasti Yasman, Yulia Yelly Oktavia Sari Yohannes Alen Yufi Aldi Yufri Aldi Yulia Yasman Yunazar Manjang Yunazar Manjang

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