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All Journal Farmaka Indonesian Journal of Pharmaceutical Science and Technology Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat Pharmacon Al-Kimia ALCHEMY Jurnal Penelitian Kimia JRST (Jurnal Riset Sains dan Teknologi) Jurnal Penelitian Farmasi Indonesia KACANEGARA Jurnal Pengabdian pada Masyarakat JSFK (Jurnal Sains Farmasi & Klinis) JURNAL PHOTON Jurnal Katalisator Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ Jurnal Ilmu Kefarmasian Indonesia Jurnal Anugerah: Jurnal Pengabdian Kepada Masyarakat Bidang Keguruan dan Ilmu Pendidikan Jurnal Empathy Pengabdian Kepada Masyarakat Yumary: Jurnal Pengabdian kepada Masyarakat Jurnal Farmasi Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Pharmaceutical Sciences and Research (PSR) Jurnal Farmasi Sains dan Praktis Jurnal Katalisator Jurnal Farmasi Indonesia Amal Ilmiah: Jurnal Pengabdian Kepada Masyarakat Jurnal Pengabdian Masyarakat Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian Jurnal Kefarmasian Indonesia Jurnal Farmasi Galenika Jurnal Farmasi Sains dan Terapan (Journal of Pharmacy Science and Practice)
Haiyul Fadhli
Sekolah Tinggi Ilmu Farmasi Riau
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Isolation of Endophytic Fungus from Leaves of Uncaria cordata (Lour.) Merr and Antibacterial Activity Against Propionibacterium acnes and Escherichia coli Melzi Octaviani; Winda Yusma Ameliah; Neni Frimayanti; Meiriza Djohari; Haiyul Fadhli
Borneo Journal of Pharmacy Vol. 5 No. 3 (2022): Borneo Journal of Pharmacy
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/bjop.v5i3.3692

Abstract

Uncaria cordata (Lour). Merr (akar kaik-kaik) is one of the medicinal plants used as antibacterial because it contains bioactive compounds that can inhibit the growth of microorganisms. The plant is one of the sources of endophyte fungal isolates that can be developed as an alternative to producing antibacterial compounds. This research aimed to isolate the endophytic fungus from the leaves of U. cordata and know the antibacterial activity against Propionibacterium acnes and Escherichia coli by disc diffusion. The Fungi that were isolated from the leaves of U. cordata were 17 isolates. The isolates were continued for antibacterial activity testing: IFED 1 (Nigrospora sp.), IFED 2 (Aspergillus sp.), IFED 3 (Fusarium sp.), and IFED 4, whose genus was unknown. The results obtained were fungal isolates IFED 1 to IFED 4 had activity in inhibiting the growth of P. acnes with moderate category (18.16 mm) and weak categories (6.21, 6.16, and 6.68 mm) and in E. coli with moderate category (14.56 mm) and weak categories (6.53, 6.71, and 7.23 mm). The results of One-Way ANOVA and Tukey's test showed a significant difference (p <0.05) between the diameter of the inhibition zone with the type of endophytic fungus supernatant isolated from the leaves of U. cordata. The best isolate of endophytic fungi inhibiting P. acnes and E. coli bacteria was IFED 1 (Nigrospora sp).
REVIEW: PHYSICAL CHARACTERISTICS, ANTIOXIDANT, ANTIBACTERIAL AND WOUND HEALING EFFECTS OF BASIL LEAVES IN SEVERAL TYPES OF PHARMACEUTICAL BASES Rodhia Ulfa; Wildan Khairi Muhtadi; Nesa Agistia; Haiyul Fadhli
Medical Sains : Jurnal Ilmiah Kefarmasian Vol 8 No 3 (2023)
Publisher : Sekolah Tinggi Farmasi Muhammadiyah Cirebon

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37874/ms.v8i3.855

Abstract

Topical preparations are dosage forms applied to the skin for local therapy. These topical preparations contain several types of bases that are used for drug formulations. This review aimed to determine the type of base that is effective and widely used in basil leaf preparations that function as antioxidants, antibacterial agents, and in wound healing. The research method is comparative, namely, reviewing research articles on formulations of basil leaf products with various concentrations of base types, hydrogels, emulgels, lotions, hydrocarbons, water solubility, absorption, water washing, M/A-type creams, and pastes. The recommended formulation is a gel base type that has physical characteristics, non-irritating properties, antioxidant activity, antibacterial activity, and wound healing. This review contained articles published in the last 10 years.  Keywords: basil leaves, base type, physical characteristics, basil leaves, pharmacological activity
Review Artikel: Tumbuhan Obat Mondokaki (Tabernaemontana divaricata (L). R.Br) Fadhli, Haiyul; Fadhila, Qonita Nur; Djohari, Meiriza; Ulfa, Rodhia
Farmaka Vol 21, No 3 (2023): Farmaka (November)
Publisher : Fakultas Farmasi, Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/farmaka.v21i3.49056

Abstract

Tanaman mondocaki (Tabernaemontana divaricata (L.R.Br.)) merupakan tanaman dalam famili Apocynaceae. Review artikel ini dibuat untuk memberikan informasi tentang kegunaan tanaman mondokaki dalam pengobatan herbal. Literatur online dan offline digunakan untuk ulasan artikel ini. Literatur online bersumber dari publikasi jurnal lokal dan internasional yang bersumber dari penyedia jurnal di internet. Literatur offline menggunakan buku atau e-book. Berdasarkan literatur yang diperoleh, tanaman ini telah digunakan secara tradisional untuk mengobati berbagai penyakit seperti patah tulang, demam, sakit kepala, dan sebagainya. Metabolit sekunder tanaman ini telah diisolasi dari daun, bunga dan batang. Bagian daunnya mengandung alkaloid indole staffinin, dimer alkaloid indole seperti conofylline dan conofylidine. Bunga tanaman ini mengandung amyrin acetate, lupeol, sitosterol, stigmasterol, flavon dan apigenin. Batangnya mengandung coronidine, heyneanin dan voacristin. Tumbuhan ini memiliki efek farmakologi seperti anti-inflamasi, anti-kanker, anti-diabetes, analgesik, antioksidan, antimikroba dan efek lainnya.
Ciplukan (Physalis angulata L.): Review Tanaman Liar yang Berpotensi Sebagai Tanaman Obat Fadhli, Haiyul; Ruska, Shinta Liana; Furi, Mustika; Suhery, Wira Noviana; Susanti, Emma; Nasution, Musyirna Rahmah
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 15 No 2 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v15i2.144

Abstract

Ciplukan (Physalis angulata L.) has been widely used as a traditional medicine in several countries and regions in Indonesia, such as to increase blood flow and relieve body aches, asthma, diabetes, chickenpox, cough medicine, fever, diarrhea, hypertension, and back pain. This article reviews the potential of ciplukan to overcome various health problems. The preparation of this review article uses references from research articles related to the results of phytochemical screening, the isolation of secondary metabolites, and biological activity tests (pharmacology) of Physalis angulata plants reported in the last 10 (ten) years. This plant contains many secondary metabolite compounds isolated from its roots, leaves, stems, and fruits, such as physalin, withanolide, and flavonoid glycoside compounds. Several studies have reported that this plant has biological and pharmacological activities such as antioxidants, toxicity, anticancer, anti-inflammatory, antidiabetic, antidiarrheal, antibacterial, antifibrotic, and anti-hypercholesterolemia.
UJI AKTIVITAS ANTIOKSIDAN DAN TABIR SURYA EKSTRAK ETANOL DAN FRAKSI DAUN TERAP (Artocarpus odoratissimus Blanco) Furi, Mustika; Feriansyah, Robby; Fadhli, Haiyul; Utami, Rahayu; Lestari, Putri
JFIOnline | Print ISSN 1412-1107 | e-ISSN 2355-696X Vol 15 No 2 (2023): Jurnal Farmasi Indonesia
Publisher : Pengurus Pusat Ikatan Apoteker Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35617/jfionline.v15i2.159

Abstract

Plants from genus Artocarpus are known containing phenolic and flavonoid compounds that have potential as antioxidant and sunscreen agent. Terap is one of species plant of Artocarpus genus, which has latin name Artocarpus odorratissimus Blanco. This present study aims to determine the antioxidant and sunscreen activity of ethanol extract and fractions of terap’s leaves. The evaluation was conducted by in vitro assay, which were the antioxidant activity was tested using the DPPH method by Microplate Reader and the sunscreen activity was analyzed using UV-Vis spectrophotometer. The results indicated that ethanol extract, ethylacetate and butanol fractions afforded very strong category of antioxidant activity with IC50 values ​​of 44.04; 42.9 and 36.49 µg/mL, respectively, while moderate activity gave by n-hexane fraction with IC50 value of 168.31 µg/mL. As for the sunscreen activity test, the most potential activity exhibited by the ethylacetate fraction at tested concentrations of 500; 250; 200; and 150 µg/mL demonstrated SPF values of 39.45; 37.36; 33.27 and 26.14, respectively; with ultra protection category as well as showed %Te and %Tp values of <1% which categorized as sunblock.
PEMANFAATAN LIMBAH KULIT BUAH NANAS (Ananas comosus (L) Merr.) SEBAGAI MINUMAN PENCERNAAN PROBIOTIK Fadhli, Haiyul; Suhery, Wira Noviana; Agustini, Tiara Tri; Ningsih, Yozi Fiedya
Jurnal Penelitian dan Pengabdian Kepada Masyarakat UNSIQ Vol 11 No 2 (2024): Mei
Publisher : Lembaga Penelitian, Penerbitan dan Pengabdian Masyarakat (LP3M) UNSIQ

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32699/ppkm.v11i2.6784

Abstract

Conventional fruit processing for food and beverage production often ignores the potential benefits of fruit peels, resulting in the presence of useless waste. Pineapple peel (Ananas comosus L. Merr) is one of the most underutilized by-products, even though it contains valuable compounds such as bromelain, flavonoids, tannins, oxalates, and phytates that have antibacterial and probiotic properties. The purpose of this community service is to provide education to increase the knowledge of the Kualu Nenas Village community about the utilization of pineapple peel waste as a prebiotic drink. The method used is counseling with colored brochure media and a demonstration of making probiotic drinks. The results obtained from 50 respondents were 48 (96%) respondents with low knowledge level, 1 (2%) respondent with sufficient knowledge level, and 1 (2%) respondent with high knowledge level. The bivariate test was carried out using the Wilcoxon method, where the test obtained the results of the p value = 0.000, which can be concluded that there is a difference or there is an effect of giving brochures on public knowledge because the p value <0.005.
UJI FITOKIMIA DAN POTENSI ANTIOKSIDAN DARI EKSTRAK KULIT KAYU GARUNGGANG Cratoxylum arborecens (Vahl) Blume: UJI FITOKIMIA DAN POTENSI ANTIOKSIDAN DARI EKSTRAK KULIT KAYU GARUNGGANG Cratoxylum arborecens (Vahl) Blume Haiyul Fadhli
JURNAL FARMASI GALENIKA Vol 6 No 2 (2019): Jurnal Farmasi Galenika Volume 6 No. 2
Publisher : Universitas Bhakti Kencana

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Gerunggang (Cratoxylum arborescens (Vahl.) Blume) is one of the plants from Hypericaceae that has benefits. From several studies that showed Hypericaceae has antioxidant activity and potential as a source of natural antioxidants. An investigation on the antioxidant activity of gerunggang extract has been done using 1-1-diphenyl-2-picrylhydrazyl (DPPH) method. The extract was obtained by macerating the stem barks of cratoxylum arborescens using n-hexane, ethyl acetate and methanol respectively. The antioxidant activity test was performed quantitative using microplate reader with ascorbic acid as a standard. The result showed that IC50 value of n-hexane extract, ethyl acetate extract and methanol extract of gerunggang sequentially 82.058 μg/mL ; 12 µg/mL and 8.335 µg/mL. methanol extract has the highest antioxidant activity that is 8.335 µg/mL.
Peningkatan Pemahaman Siswa Tentang Swamedikasi Diare Melalui Edukasi Interaktif Fadhli, Haiyul; Wulandari, Venny; Sandra Tsalsabila Ananto, Deswita; Putri Pratiwi, Amanda; Arif Arsaf, Mohammad
Jurnal Empathy Pengabdian Kepada Masyarakat Jurnal Empathy Pengabdian Kepada Masyarakat Volume 5 Nomor 2 Tahun 2024
Publisher : Poltekkes Kemenkes Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37341/jurnalempathy.v5i2.277

Abstract

Background: The practice of self-medication for diarrhea remains irrationally performed by the community, including students. The lack of health education in schools contributes to students' lack of knowledge about self-medication of diarrhea. The purpose of this activity is to improve students' understanding of diarrhea self-medication through an interactive educational approach. Methods: This community service utilized a descriptive observational method, incorporating a pretest and posttest approach. Interventions were conducted through interactive discussions and question-and-answer sessions. They are encouraging active student participation. Results: Before the intervention, only three students could correctly answer questions regarding self-medication for diarrhea. After interactive education, the level of understanding increased significantly to 80%. Conclusion: Interactive education has proven effective in enhancing students' knowledge of self-medication for diarrhea. This approach holds potential for sustainable implementation in school health education programs, aiming to raise students' awareness and understanding.
Meningkatkan potensi kreatif dan motorik halus anak usia dini dengan kolase bahan alam Fadhli, Haiyul; Fellysya, Nadya Safha; Alfayutia, Windi; Putri, Rusnita; Arsaf, Muhammad Arif
Jurnal Anugerah Vol 6 No 2 (2024): Jurnal Anugerah: Jurnal Pengabdian kepada Masyarakat Bidang Keguruan dan Ilmu Pen
Publisher : Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/anugerah.v6i2.7302

Abstract

Komponen utama dari pendidikan anak usia dini adalah pengembangan kreativitas dan keterampilan motorik halus, karena sifat-sifat ini memengaruhi kapasitas kognitif dan sosial pada masa depan. Melalui kegiatan kolase, program pengabdian ini bertujuan untuk meningkatkan kemampuan motorik halus dan kreativitas anak-anak di TK Permata Ibu dan RA Mutiara Hati. Kegiatan kolase dipilih karena memungkinkan eksplorasi bahan alam yang merangsang imajinasi dan keterampilan motorik halus. Peserta dalam pengabdian ini adalah 57 peserta didik berusia 4-6 tahun. Teknik pengumpulan data mencakup observasi yang dinilai berdasarkan ketepatan, koordinasi tangan-mata, dan kreativitas dalam menata bahan kolase dan analisis hasil kerapian dalam penempelan bahan alam pada kolase. Data dianalisis menggunakan teknik analisis deskriptif untuk mengevaluasi peningkatan keterampilan motorik halus dan kreativitas anak. Anak-anak dapat mengembangkan keterampilan koordinasi tangan-mata, ketepatan dalam menempel bahan, dan kreativitas saat menata kolase. Hasil ini menegaskan bahwa kegiatan kolase dapat menjadi metode pembelajaran efektif untuk pengembangan kreativitas dan motorik halus anak usia dini. Kegiatan ini juga menunjukkan potensi untuk diperluas dengan melibatkan variasi bahan alam yang lebih beragam.
Cytotoxic activity of isolate compounds from derendan (Lansium parasiticum (Osbeck) K.C. Sahni & Bennet) fruit peel Fadhli, Haiyul; Rahmayanı, Wıky; Allaya, Regina; Jumadila, Ikhsal Mukri; Fernando, Armon; Utami, Rahayu
JURNAL ILMU KEFARMASIAN INDONESIA Vol 22 No 1 (2024): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v22i1.1309

Abstract

Derendan (Lansium parasiticum (Osbeck) K.C. Sahni & Bennet) is a plant from the Meliaceae family that grows in the tropics, especially in Sumatra (Indonesia). It was reported that this plant has antimalarial, antimutagenic, and anticancer properties. This study aims to determine the cytotoxic activity of compounds isolated from the methanol extract of Lansium parasiticum bark. Extraction using maceration method with methanol solvent. Vacuum Liquid Chromatography (KVC) with 21 different eluent ratios (n-hexane : ethyl acetate and ethyl acetate ; methanol) was utilized for the fractionation. The result was 21 fractions. The washing technique was used to purify fraction 17. The obtained compound LPR17 with a melting point of 239-241ᵒC. Based on the UV spectrum, the wavelengths of the LPR17 compound were 277.0 nm and 205.0 nm. The FT-IR spectrum shows aliphatic OH, CH, C=O, C-H, and C-C functional groups. This compound reacts positively with the Liebermann-Burchard reagent. The compound obtained is a triterpenoid group. Cytotoxic test using BSLT method. LPR17 compounds provide very strong cytotoxic activity (LC50 = 67.15 g/mL).
Co-Authors Abdi Wira Septama Adel Zamri Adriani Susanty agistia, nesa Agustini, Tiara Tri Ainun Nurain Nurdin Ainun Nurain Nurdin Alfayutia, Windi Allaya, Regina Alpasiri, Ikhsan Mauludi Ananto, Deswita Sandra Tsalsabila Andika Bharada Rizky Soeharto Anggraeni, Ica Winanda Anggraini, Silvana Anita Lukman Apriko Jauwahir Arif Arsaf, Mohammad Armon Fernando Arsaf, Mohammad Arif Arsaf, Muhammad Arif Asraf, Muhammad Arif Azizah, Wahyu BENNI ISKANDAR Dachriyanus Devi Safitri Dewi, Erna Puspita Difa, Faradini Ramsanjami DINA FITRIYAH Dwi Winarsih Emrizal Enda Mora Erenda Yuneistya Erna Puspita Dewi Fadhila, Qonita Nur Fadillah, Ma’isyatul Fatma Sri Wahyuni Fatmalia, Anggun Fellysya, Nadya Safha Feriansyah, Robby Fina Aryani, Fina Fitriah, Dina Frasesa, Roscha Ulfa Furi, Mustika Ginta Rio Maranti Hazimah Hazimah, Hazimah Husnawati Husnawati Husnawati Ihsan Ikhtiarudin Iriani, Revy Islamia, Elmas Ghalis Nur Jasril Jasril Jumadila, Ikhsal Mukri Kamil, Marshal M. Khoiriah, Anisah Maqfiroh, Wirdarani Mardianti, Tengku Shella Maspat, Rinta Meiriza Djohari, Meiriza Melzi Octaviani Miftahul Jannah Mudia, Whulan Muhtadi, Wildan Khairi Musyirna Rahmah Nst Muti’ah, Try Hadirah Nadilla Alfitri Neni Frimayanti Ningsih, Yozi Fiedya Nofri Hendri Sandi Noveri Rahmawati Nur Fitria Rohmatul Ummah Nurul fadillah, Nurul Pedro Anugrah Aswan Pratiwi, Amanda Putri Pratiwi, Erniza Putra, Diova Yuswidia Putri Lestari Putri Lestari, Putri Putri Pratiwi, Amanda Putri, Hefriza Putri, Rusnita Putri, Sella Hilmalia Nur Al Rahayu Utami Rahayu Utami Rahayu Utami Utami Rahima Rahma Dona Rahma Dona, Rahma Rahmatunnur, Siti Rahmayanı, Wıky Rahmiwati Hilma Ricardo, Nadira Atiqah Rifani, Mhd Rizki Wulandari Robiatun Adawiyah Rodhia Ulfa Ronapadua Musyirna Rahmah Nasution Sahara dan Emma Susanti Ruska, Shinta Liana Sajja Wanda, Taqqia Sandra Tsalsabila Ananto, Deswita Sari, Rinita Septi Muharni Siregar, Lisa Andriyani Sitanggang, Sarah Dianora Sumbarita, Silvia Trihardiyanto, Agus Tyasakti Viryana Ulfa Frasesa, Roscha Veithzal Rivai Zainal Viryana, Tyasakti Wanda, Taqqia Sajja Winda Tria Safitri Winda Yusma Ameliah Windarti Windarti Wira Noviana, Wira Noviana Wulandari, Venny Yanwirasti Yanwirasti Yuneistya, Erenda Yuswidia Putra, Diova Zamri, Wiedya Alfitrya