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All Journal International Journal of Evaluation and Research in Education (IJERE) Jurnal Pendidikan Matematika Journal of Education and Learning (EduLearn) Pharmaciana: Jurnal Kefarmasian Jurnal Infinity AKSIOMA: Jurnal Program Studi Pendidikan Matematika Mutiara Medika: Jurnal Kedokteran dan Kesehatan Science and Technology Indonesia Union: Jurnal Ilmiah Pendidikan Matematika REiD (Research and Evaluation in Education) Jurnal Surya Medika Jurnal Berkala Kesehatan JPKMI (Jurnal Publikasi Kesehatan Masyarakat Indonesia) Journal of Mathematics and Mathematics Education (JMME) Procediamath Media Ilmu Kesehatan Theorems (The Original Research of Mathematics) Malikussaleh Journal of Mathematics Learning (MJML) SJME (Supremum Journal of Mathematics Education) Gammath : Jurnal Ilmiah Program Studi Pendidikan Matematika Jurnal Didactical Mathematics Jurnal Penelitian Pembelajaran Matematika Sekolah Jurnal Ners An-Nadaa: Jurnal Kesehatan Masyarakat Jurnal Educatio FKIP UNMA BERNAS: Jurnal Pengabdian Kepada Masyarakat Southeast Asian Mathematics Education Journal Community Empowerment Mosharafa: Jurnal Pendidikan Matematika Plusminus: Jurnal Pendidikan Matematika Jurnal Neuroanestesi Indonesia Makara Journal of Technology Progressive of Cognitive and Ability Journal of Research in Science and Mathematics Education INCOME: Indonesian Journal of Community Service and Engagement Indonesian journal of teaching and learning International Journal of Contemporary Studies in Education JNPM (Jurnal Nasional Pendidikan Matematika) International Journal of Mathematics and Mathematics Education (IJMME) Journal of Community Service (JCOS) Journal of Literature Language and Academic Studies (J-LLANS) JRAMathEdu (Journal of Research and Advances in Mathematics Education) Jurnal Infinity International Journal of Applied Learning and Research in Algebra International Journal of Geometry Research and Inventions in Education Jurnal Pendidikan MIPA Jurnal Pendidikan Progresif Mathematics Education Journal SJME (Supremum Journal of Mathematics Education) Eduma : Mathematics Education Learning and Teaching
Nia Kania
Universitas Majalengka, Indonesia
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Dentistry Economics, Econometrics & Finance Education Electrical & Electronics Engineering Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Library & Information Science Materials Science & Nanotechnology Mathematics Mechanical Engineering Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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The Potential of Ethanol Extract of Pasak Bumi Roots (Eurycoma longifolia Jack) as an Anti-Prostate Cancer In Vitro Against PC-3 Cells Kania, Nia; Rahman, Eka Yudha; Priyandoko, Didik; Sabrina, Adilah Hafizha Nur; Widowati, Wahyu; Azis, Rizal; Annaba, Aziz; Hadiprasetyo, Dhanar Septyawan; Alexandro, Garry
Science and Technology Indonesia Vol. 10 No. 2 (2025): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26554/sti.2025.10.2.452-466

Abstract

The prevalence of prostate cancer cases in men is expected to continue increase. In 2040, it is estimated that there will be 2.293.818 new cases and a 1.05% increase in the death rate due to prostate cancer. Eurycoma longifolia Jack roots extract (ELE) has potential as an alternative treatment. This study aims to analyze ELE potential as an anti-prostate cancer agent through in silico assay and in vitro assays on the prostate cancer cell line (PC-3). ELE compounds were docked against Casp-3, Casp-8, HAX-1, p27, and PTEN. In vitro assays on PC-3 cells were used, namely cell viability (WST-8), ROS levels; cell cycle; and cell apoptosis (flow cytometry), PC-3 cell senescence (μ-Galactosidase staining), Casp-3; Casp-8; HAX-1; p27; and PTEN gene expression (qRT-PCR). All proteins target were successfully docked with ELE compounds and presented binding interactions. ELE is known to reduce viability, intracellular ROS levels, live cells, necrosis, and reduce HAX-1 gene expression, and inhibit the cell cycle G0/G1 phase. ELE can also increase inhibition, senescence, late and early apoptosis, and Casp-3, Casp-8, p27, and PTEN gene expression. ELE 100 μg/mL is the most effective concentration. ELE has potential as an anti-prostate cancer agent through apoptosis, cell cycle, and antioxidant pathways
Acute oral toxicity test and determination of lethal dose (LD50) of Garcinia forbesii King leaf extract in wistar rats Rudiansyah, Mohammad; Rosida, Azma; Kania, Nia; Devi, Wivina Riza; Nirmalasari, Nila
Pharmaciana Vol. 15 No. 1 (2025): Pharmaciana
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/pharmaciana.v15i1.29616

Abstract

Garcinia forbesii King, an endemic plant from Sumatra and Kalimantan, is traditionally used for treating skin infections and inflammation. Its potential use as a raw material for medicines needs to be supported by safety tests. The purpose of this study is to assess the acute toxicity of its 70% leaf extract in male Wistar rats, evaluating clinical symptoms, body weight changes, organ indices, and the lethal dose (LD50). The study administered extract doses orally at 5 (G2), 50 (G3), 300 (G4), and 2,000 (G5) mg/kg BW, monitoring toxicity signs over 14 days. Symptoms such as piloerection, respiratory distress, and soft feces were noted. Significant weight loss was observed at doses of 2,000 mg/kg BW. There was no significant effect on the kidney index, but the liver and heart indices exhibited significantly lower changes compared to the control. The LD50 value was estimated to be between 2,000-5,000 mg/kg BW. Further studies are recommended to assess histopathological effects and identify harmful chemicals in the plant.
How to Learning Arithmetic Sequences with Project-Based Learning in Terrace Culture? Nurhikmayati, Iik; Kania, Nia
Mathematics Education Journal Vol. 15 No. 2 (2021): Jurnal Pendidikan Matematika
Publisher : Universitas Sriwijaya in collaboration with Indonesian Mathematical Society (IndoMS)

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

Integrating mathematics into local culture is a way to enhance students' interest in local wisdom. The concept of mathematics is explored to find out the existence of mathematics in society's culture which has not been seen so far. The Mathematical concept is used to explore the existence of mathematics in terrace culture on the Panyaweuyan terrace of Majalengka city. This study to describe the result of exploratory project-based learning of the Panyaweuyan terrace with this kind of exploratory research. The exploring of the relationship between the terrace culture of panyaweuyan and concept mathematics, especially in the concept of arithmetic sequences is analyzed and described through literature studies, observation, and interviews with 4 informants who are local farmers. The results that there is a relationship between the arithmetic sequence concept with the local culture of Panyaweuyan Majalengka city. The results of the study stated that each mound on each step on the Panyeweuyan terraces was formed through an arithmetic sequence formula. Farmers in Panyaweuyan terraces are naturally able to make terraces according to the arithmetic sequence formula without knowing the basics of mathematics. Therefore, the concept of mathematics is part of local culture which has an important role in preserving the nation's culture. DOI: https://doi.org/10.22342/jpm.15.2.13800.133-144
PENGEMBANGAN MODUL AJAR MATEMATIKA DENGAN MODEL PROBLEM BASED LEARNING UNTUK MENINGKATKAN KEMAMPUAN BERPIKIR KRITIS MATEMATIS Hariri, Dewi Damayanti; Nurhikmayati, Iik; Kania, Nia
JP2MS Vol 9 No 1 (2025): April
Publisher : Program Studi S1 Pendidikan Matematika FKIP Universitas Bengkulu

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/jp2ms.9.1.1-12

Abstract

Kemampuan berpikir kritis adalah kemampuan kognitif yang mendorong siswa untuk mempertimbangkan masalah secara kritis yang Dmembutuhkan kemampuan berpikir induktif termasuk mengidentifikasi hubungan, mengevaluasi situasi terbuka, mencari tahu sebab dan akibat, membuat deduksi, dan menghitung data yang relevan. Penelitian ini bertujuan untuk mengembangkan modul ajar berbasis Problem Based Learning (PBL) pada materi Sistem Persamaan Linear Tiga Variabel (SPLTV) untuk meningkatkan kemampuan berpikir kritis matematis siswa. Menggunakan metodologi Research and Development (R&D) dengan pendekatan ADDIE, modul ajar ini melalui tahap analisis, desain dan pengembangan. Instrumen penelitian terdiri dari lembar validasi oleh ahli media dan materi, serta kuesioner kepraktisan untuk guru dan siswa. Data dianalisis menggunakan skala Likert untuk mengukur validitas dan kepraktisan modul. Hasil penelitian menunjukkan bahwa modul ajar matematika dengan PBL yang dikembangkan telah memenuhi kriteria valid dan praktis ditinjau dari kemampuan berpikir kritis matematis. Keberhasilan penelitian ini didukung oleh pendekatan kontekstual yang meningkatkan keterlibatan siswa dalam pembelajaran. Dampak penelitian ini terhadap pembelajaran matematika adalah peningkatan pemahaman siswa terhadap materi SPLTV dan kemampuan berpikir kritis, yang penting untuk menghadapi tantangan dalam pendidikan abad ke-21.
Analisis Faktor Yang Berhubungan Dengan Kejadian Anemia Pada Remaja Putri SLTA Wilayah Kerja UPTD. Puskesmas Tamiang Layang Mardini, Heni; Sanyoto, Didik Dwi; Ringoringo, Harapan Parlindungan; Audhah, Nelly Al; Kania, Nia
An-Nadaa: Jurnal Kesehatan Masyarakat (e-Journal) Vol 12, No 1 (2025): AN-NADAA JURNAL KESEHATAN MASYARAKAT (JUNI)
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/ann.v12i1.14433

Abstract

Anemia adalah kondisi di mana jumlah sel darah merah menurun dan kadar hemoglobin kurang dari nilai normal. Wanita pada usia remaja adalah kelompok usia yang berisiko tinggi menderita anemia. Anemia tertinggi di Kabupaten Barito Timur di di wilayah kerja UPTD Puskesmas Tamiang Layang sebesar 61,46%. Mengetahui hubungan antara kejadian anemia pada remaja putri  di SLTA wilayah kerja UPTD Puskesmas Tamiang Layang Penelitian bersifat observasional analitik menggunakan pendekatan cross sectional dengan populasi 447 orang didapatkan 103 orang sebagai sampel menggunakan teknik purposive Sampling. Instrumen penelitian adalah kuesioner. Variabel terikat:anemia. Variabel bebas: pengetahuan, sikap, asupan suplemen zat besi, pendapatan orang tua, dan pendidikan ibu. Analisis bivariat menggunakan chi square dan multivariat menggunakan regresi logistik berganda Hasil penelitian menunjukkan terdapat hubungan antara Pengetahuan (p=0,000), sikap(p=0,000), Asupan Suplemen Zat Besi (p=0,000), Pendapatan  orang tua(p=0,003), dan pendidikan ibu (p=0,000). Variabel pengetahuan paling berhubungan dengan kejadian anemia pada remaja putri. (Exp(B)= 23,560). Pengetahuan, sikap, asupan suplemen zat besi, pendapatan orang tua, dan pendidikan ibu adalah variabel yang paling berhubungan dengan kejadian anemia. Kata Kunci : Anemia, Asupan suplemen zat besi, Pendapatan orang tua, Pengetahuan, Pendidikan Ibu, dan sikap
Analysis Of Factors Associated With Utilisation Of Health Services In Inpatients UPT. RSUD Kuala Kurun Perdias, Antonio; Noor, Zairin; Istiqomah, Ermina; Kania, Nia; Tri Febriana, Silvia Kristanti
An-Nadaa: Jurnal Kesehatan Masyarakat (e-Journal) Vol 12, No 1 (2025): AN-NADAA JURNAL KESEHATAN MASYARAKAT (JUNI)
Publisher : Universitas Islam Kalimantan Muhammad Arsyad Al Banjari Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31602/ann.v12i1.17812

Abstract

Utilisation of health services at UPT. RSUD Kuala Kurun in the last two years has decreased. Factors that influence the utilisation of health services include education level, accessibility, and facilities. To determine the relationship between education level, accessibility, and facilities with the utilisation of health services among inpatients at the Kuala Kurun Regional Hospital. This study used a cross sectional design. The research subjects consisted of 105 people at UPT Kuala Kurun Hospital. Data analysis chi square test and multiple logistic regression test. The results showed that the most dominant variables related to the utilisation of health services in inpatients of UPT. RSUD Kuala Kurun were accessibility (13,022), education level (6,690), and facilities (3,638). There is a relationship between the level of education, accessibility and facilities to the utilisation of health services in inpatients UPT. RSUD Kuala Kurun. The most dominant variable is accessibility.
Designing a Geometry Examination Framework to Evaluate Higher-Order Thinking Skills Kania, Nia; Nurhikmayati, Iik; Larsari, Vahid Norouzi
International Journal of Geometry Research and Inventions in Education Vol. 2 No. 01 (2025)
Publisher : EDUPEDIA Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56855/gradient.v2i02.1327

Abstract

This study aims to develop a valid, practical, and effective instrument for assessing higher-order thinking skills (HOTS) in junior high school mathematics. Employing a research and development (R&D) approach, the study adapts Mardapi's (2008) development model, which includes nine stages. However, this research focuses on the first seven stages, leaving the final implementation to teachers in schools. The instrument was tested on 40 students at SMPN 2 Rajagaluh, Majalengka Regency. The validity analysis demonstrated that all V values exceeded 0.3, indicating strong content validity. Reliability testing yielded a Cronbach's Alpha score of 0.52, suggesting moderate internal consistency. The findings revealed that students' HOTS performance remains suboptimal, highlighting the need for targeted instructional strategies. Strengthening HOTS can be achieved through structured practice with complex problem-solving tasks. This study provides a robust framework for educators to assess and enhance students’ critical thinking abilities in mathematics.
Analisis Faktor Risiko Penyebab Tidak Langsung Kejadian Stunting: Risk Factors Analysis of Indirect Causes of Stunting Incidents Azmiyannoor, Muhammad; Kania, Nia; Hartoyo, Edi
Jurnal Surya Medika (JSM) Vol. 11 No. 1 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.9765

Abstract

Stunting merupakan permasalahan gizi kronis dengan ciri anak memiliki perawakan pendek yang disebakan oleh penyebab langsung dan tidak langsung. Penelitian dilakukan untuk menganalisis hubungan antara faktor-faktor penyebab tidak langsung berupa ketahanan pangan, pola pemberian makan, akses air bersih, dan kepemilikan jamban layak dengan kejadian stunting melalui pendekatan tinjauan literatur. Data dikumpulkan dari berbagai artikel ilmiah yang relevan menggunakan metode pencarian sistematis melalui Google Scholar dengan kriteria inklusi dan eksklusi tertentu. Hasil analisis terhadap 22 artikel menunjukkan bahwa ketahanan pangan yang rendah, pola pemberian makan yang tidak sesuai, keterbatasan akses terhadap air bersih, serta kepemilikan jamban yang tidak layak berkontribusi terhadap meningkatnya risiko stunting pada balita. Sebagian besar studi menunjukkan adanya hubungan yang signifikan antara faktor-faktor tersebut dengan kejadian stunting, meskipun beberapa penelitian tidak menemukan hubungan yang bermakna. Kesimpulannya, faktor-faktor tidak langsung memiliki peran penting dalam kejadian stunting, sehingga diperlukan pendekatan komprehensif dalam pencegahan dan penanggulangan stunting dengan meningkatkan akses terhadap pangan bergizi, edukasi pola pemberian makan, serta perbaikan infrastruktur sanitasi dan air bersih.
Enhancing healthcare professionals’ capacity in early detection of prostate cancer Rahman, Eka Yudha; Panghiyangani, Roselina; Kania, Nia; Sutapa, Hendra; Yulizar, Deddy Rasyidan; Budiwinata, Winardi; Skripsiana, Nika Sterina; Rachman, M. Fathur; Fatharoni, Gusti Dicky; Fahdyanoor, Fahdyanoor
Community Empowerment Vol 10 No 5 (2025)
Publisher : Universitas Muhammadiyah Magelang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31603/ce.12241

Abstract

Prostate cancer is globally the second most common malignancy and the sixth leading cause of cancer-related death in men. The growing elderly population in Banjarbaru City, South Kalimantan, further elevates the risk of prostate cancer incidence in the region. Therefore, this community service initiative aimed to improve the knowledge and skills of healthcare professionals serving the elderly within the working area of the Banjarbaru City Health Office in early detection and prevention of prostate cancer. The activity was conducted as a comprehensive training involving 20 healthcare professionals, encompassing both theoretical and practical sessions. Training outcomes revealed a significant increase in participants' knowledge, evidenced by an average pre-test score of 55.91 which rose to an average post-test score of 84.35. Additionally, there was a noticeable improvement in healthcare professionals' skills in performing early detection and preventive measures for prostate cancer. Overall, this training successfully enhanced the capacity of healthcare professionals in Banjarbaru City in the early management of prostate cancer.
Phenomenological Hermeneutic Study on the Epistemological Obstacles of High School Students in Solving Combinatorics Problems Nopriana, Tri; Asnawati, Sri; Kania, Nia
Southeast Asian Mathematics Education Journal Vol 15, No 1 (2025)
Publisher : SEAMEO Regional Centre for QITEP in Mathematics

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.46517/seamej.v15i1.468

Abstract

This study employs a hermeneutic phenomenological approach to explore students' epistemological obstacles in solving permutation and combination problems, with the goal of supporting the development of more effective teaching materials. The research involved 24 12th-grade high school students (14 males and 10 females) and used qualitative methods. Data were collected through five diagnostic essay questions and semi-structured interviews to identify epistemological obstacles in combinatorics. Students’ written responses and interview transcripts were analyzed and interpreted to uncover the underlying obstacles. The findings revealed several epistemological obstacles: (1) students were unable to identify all possible answers from a given problem; (2) students could not differentiate between problems requiring the concept of permutation and those requiring the concept of combination; (3) students struggled to solve problems that differed from the example problems provided; and (4) challenges in formulating a complete solution when faced with multiple conditions, despite being able to calculate partial results. These insights suggest that teachers and future researchers should consider students' epistemological obstacles when designing instructional materials, particularly for topics in combinatorics such as permutations and combinations. Developing learning resources based on these findings may enhance conceptual understanding and problem-solving skills among students.
Co-Authors Aep Saepudin Aep Sunendar Agung Ary Wibowo, Agung Ary Agus Suhendar, Agus Akhmad Gazali Alexandro, Garry Amat Hidayat Anggraini, Farida Anggun Apriliani Angra Meta Ruswana Annaba, Aziz Anton Nasrullah, Anton Apriliani, Anggun Arcat Ariani, Risna Aulia Nisa Trisna Ihsani Azis, Rizal Azma Rosida, Azma Azmiyannoor, Muhammad Betty Kusumaningrum Bonyah, Ebenezer Budiwinata, Winardi Dadang Juandi Dadang Juandi Dede Eti Nurhasanah Devi, Wivina Riza Dewi Fitriyani Dian Ana Mutriqah Didi Suryadi Didik Priyandoko Ebenezer Bonyah Ebenezer Bonyah Edi Hartoyo Eka Yudha Rahman Eko Suhartono Elah Nurlaelah Elah Nurlaelah Elis Rosmawati Elsayed, Ebrahim E. Erik Santoso Erik Santoso Ermina Istiqomah, Ermina Esabilita, Monica Fahdyanoor, Fahdyanoor Fath, Tri Putra Nuur Fatharoni, Gusti Dicky Febriana Kristanti Ferit Gí¼rbí¼z Fitria Sulistyowati Fitriani, Cut Florence Kyaruzi Florence M. Kyaruzi Gürbüz, Ferit Hadiprasetyo, Dhanar Septyawan hanipah, Hani Harapan Parlindungan Ringoringo, Harapan Parlindungan Hardyan Sauqi Hariri, Dewi Damayanti Haryanti, Yuyun Dwi Hendriyanto, Agus Herawati , Herawati Hilda Mahmudah Huldani Huldani Ida Ayu Putu Sri Widnyani Iik Nurhikmayati Iik Nurhikmayati, Iik Ilham Muhammad Isma Nurhasanah Istiqamah, Ermina Istiqamah Iva Faridayanti Jajang Rahmatudin Jarnawi Afgani Dahlan Julia, Rida Khairunnisa Khairunnisa Krida Singgih Kuncoro Krida Singgih Kuncoro Kyaruzi, Florence Larsari, Vahid Norouzi Lilis Marina Angraini M. Arif Hakim M. Gilar Jatisunda Mahmudah, Hilda Mardini, Heni Melis Rosdiani Mijani Rahman, Mijani Mira Sagita Mohamad Gilar Jatisunda Mohammad Bakhriansyah Mohammad Rudiansyah Muhammad Abdan Shadiqi Muhammad Azam Muthia Elma Nelly Al Audhah Nila Nirmalasari, Nila Noor, M. Hafidhuddin Noor, Meitira Syahadatina Nunuy Ratnawulan Nunuy Ratnawulan Oski Illiandri Perdias, Antonio Poerwosusanta, Hery Pratama, Muhammad Noor Aditya Pratiwi, Amalia E. Rachman, M. Fathur Rahma, Aulia Rampun, Erdina L.A. Ratnawulan, Nunuy Rika Septianingsih Rismawati, Silvyra Rismayani Rismayani Roselina Panghiyangani Sabrina, Adilah Hafizha Nur Sanyoto, Didik Dwi Silvia Kristanti Tri Febriana Skripsiana, Nika Sterina Sri Asnawati, Sri Suci Trian Meliana Sudianto Sudianto Sudianto, Sudianto Suhana, Nono Sutapa, Hendra Tasya Indri Rangkuti Tri Nopriana, Tri Triawanti Triawanti Triawanti Umar, Nasir Vahid Norouzi Larsari Vici Suciawati WAHYU WIDOWATI Wibawa, Fayza Sandya Yasir Yasir Yaya S. Kusumah Yaya S. Kusumah Yeni dwi Kurino Yonanda, Devi Afriyuni Yulizar, Deddy Rasyidan Yusup Maulana Zaenal Arifin Zaenal Arifin Zaenal Arifin Zaenal Arifin Zaenal Arifin Zaenal Arifin Zainal Abidin Zairin Noor