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All Journal PHARMACON Jurnal Surya Medika Syntax Literate: Jurnal Ilmiah Indonesia Pharmacology and Clinical Pharmacy Research KACANEGARA Jurnal Pengabdian pada Masyarakat GUIDENA: Jurnal Ilmu Pendidikan, Psikologi, Bimbingan dan Konseling Martabe : Jurnal Pengabdian Kepada Masyarakat IJISTECH (International Journal Of Information System & Technology) PHARMACY: Jurnal Farmasi Indonesia (Pharmaceutical Journal of Indonesia) JIK- JURNAL ILMU KESEHATAN Journal of Education, Humaniora and Social Sciences (JEHSS) Jurnal Hukum Positum Jurnal Sehat Mandiri Jurnal Abdimas PHB : Jurnal Pengabdian Masyarakat Progresif Humanis Brainstorming Jurnal Dunia Farmasi Jurnal Pendidikan dan Konseling Jurnal Kesehatan Masyarakat Celebes Best Journal (Biology Education, Sains and Technology) Jurnal ABDINUS : Jurnal Pengabdian Nusantara Jurnal Riset Kefarmasian Indonesia HSG (Health Science Growth) Journal Lumbung Farmasi : Jurnal Ilmu Kefarmasian Jurnal Penelitian Farmasi dan Herbal IJISTECH Jurnal Ilmiah Wahana Pendidikan Jurnal EduHealth Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Jurnal Pemberdayaan dan Pendidikan Kesehatan Jurnal Farmasetis Journal of Sustainable Community Service Journal of Pharmaceutical and Sciences. JUKEJ: Jurnal Kesehatan Jompa Jurnal Kesehatan Cendikia Jenius Jurnal Sains dan Kesehatan Jurnal Bioteknologi & Biosains Indonesia (JBBI) Jurnal Bioteknologi & Biosains Indonesia Preventif : Jurnal Kesehatan Masyarakat Jurnal Abdimas Mahakam Journal of Pharmascience
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Faktor yang Mempengaruhi Penggunaan Obat Kategori Over the Counter pada Mahasiswa UNSIKA: Factors Affecting the Use of Over the Counter Drug Categories In UNSIKA Students Rahmi Indiani; Mally Ghinan Sholih; Indah Laily Hilmi
Jurnal Sains dan Kesehatan Vol. 5 No. 4 (2023): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v5i4.1364

Abstract

Survey conducted by the Statistics Indonesia in 2020 regarding self-medication, it was recorded that 88,28% people of West Java carried out self-medication, one of which was with over the counter drugs. The high use of this Over The Counter (OTC) category of drugs increases the possibility of abuse in terms of use. The purpose of this study is to identify the factors that influence the use of drugs in the OTC category and to test it againts Singaperbangsa Karawang University (UNSIKA) students. This research was conducted from January to March 2022 using a descriptive analytic design with a cross sectional approach. The instrument used is a questionnaire. The sampling technique used is the accidental sampling method with a sample consisting of 392 UNSIKA students who entered the inclusion criteria. The results of the univariate analysis shows that the majority of respondents have good knowledge, are influenced by product effectiveness and efficiency, have adequate information availability, believe in manufacturers, are influenced by usage preferences, and use drugs well. The results of the bivariate analysis using the Chi square method indicates that there is a relationship between knowledge, trust in manufacturers, and usage preferences for the use of drugs in the OTC category with a significance value of 0.001 (p 0.05). Keywords: OTC, drug use, self-medication, student Abstrak Survei Badan Pusat Statistik tahun 2020 tentang pengobatan mandiri menunjukkan 88,28% masyarakat Jawa Barat melakukan swamedikasi salah satunya dengan obat kategori over the counter. Tingginya penggunaan obat kategori Over The Counter (OTC) ini meningkatkan kemungkinan terjadinya penyalahgunaan dalam hal penggunaan obat. Tujuan penelitian ini adalah identifikasi faktor-faktor apa saja yang mempengaruhi penggunaan obat kategori OTC dan membuktikan faktor-faktor yang mempengaruhi penggunaan obat kategori OTC pada mahasiswa Universitas Singaperbangsa Karawang (UNSIKA). Penelitian ini dilakukan pada bulan Januari sampai Maret 2022 menggunakan desain deskriptif analitik dengan pendekatan cross sectional. Instrumen yang digunakan berupa kuesioner. Teknik pengambilan sampel menggunakan metode accidental sampling dengan sampel terdiri dari 392 mahasiswa UNSIKA yang masuk ke dalam kriteria inklusi. Hasil analisis univariat mayoritas responden berpengetahuan baik, dipengaruhi efektivitas dan efisiensi produk dengan baik, memiliki ketersediaan informasi yang memadai, percaya terhadap produsen, dipengaruhi preferensi pemakaian, dan menggunakan obat dengan baik. Hasil analisis bivariat menggunakan metode chi square terdapat hubungan antara pengetahuan, kepercayaan terhadap produsen, dan preferensi pemakaian terhadap penggunaan obat kategori OTC dengan nilai signifikansi 0,001 (p <0,05) dan tidak terdapat hubungan antara efektivitas dan efisiensi produk serta ketersediaan informasi terhadap penggunaan obat kategori over the counter dengan nilai signifikansi berturut-turut sebesar 0,911 dan 0,973 (p > 0,05). Kata Kunci: OTC, penggunaan obat, swamedikasi, mahasiswa
Literatur Review: Efektivitas Konseling Farmasis Terhadap Kepatuhan Minum Obat pada Diabetes Melitus Tipe 2: Literature Review: Effectiveness of Pharmacist Counseling on Compliance with Taking Medication in Diabetes Mellitus Type 2 Nurdin, Fitri Oktaviani; Hilmi, Indah Laily; Sudarjat, Hadi; Yulianti Surasa, Triana Maudy
Jurnal Surya Medika (JSM) Vol. 11 No. 1 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.9723

Abstract

Diabetes Melitus (DM) tipe 2 merupakan penyakit metabolik kronis yang memerlukan pengobatan seumur hidup. Salah satu faktor yang memengaruhi keberhasilan terapi DM adalah tingkat kepatuhan pasien terhadap pengobatan. Ketidakpatuhan ini sering kali disebabkan oleh kurangnya pemahaman pasien tentang pentingnya pengobatan jangka panjang. Tujuan: mengevaluasi efektivitas konseling farmasis dalam meningkatkan kepatuhan penggunaan obat pada pasien diabetes mellitus tipe 2. Metode yang digunakan adalah narrative review terhadap artikel yang membahas dampak konseling terhadap kepatuhan pasien. Hasil: Analisis 10 artikel memperlihatkan konseling oleh farmasis secara signifikan meningkatkan kepatuhan pengobatan, menurunkan kadar gula darah, serta memperbaiki hasil klinis secara keseluruhan. Kesimpulan: konseling farmasis merupakan intervensi yang efektif dalam meningkatkan kepatuhan pengobatan dan kontrol glukosa darah, yang berpotensi meningkatkan kualitas hidup pasien diabetes.
Analysis of the Side Effects of Long-Term Proton Pump Inhibitor (PPI) Use in Patients with Gastroesophageal Reflux Disease (GERD) Nurhafidah, Zahra; Hilmi, Indah Laily; Sudarjat, Hadi
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1628

Abstract

Background: Proton Pump Inhibitors (PPIs) are widely prescribed to manage gastrointestinal disorders, especially gastroesophageal reflux disease (GERD). However, long-term PPI use has been linked to serious side effects and potential complications. Objective: This study aims to analyze the side effects associated with prolonged PPI use in patients with GERD. Methods: A systematic review was conducted using Google Scholar and PubMed databases with relevant keywords. Article selection was carried out carefully based on inclusion and exclusion criteria to ensure the quality and relevance of the data. Additionally, a bibliometric analysis was performed to explore research trends related to the long-term use of PPIs. Results: The review found that prolonged PPI use is associated with various adverse effects, including an increased risk of dementia, progression of chronic kidney disease (CKD), gastric cancer, bone fractures, Frailty Syndrome, hypomagnesemia, iron deficiency, vitamin B12 deficiency, myocardial infarction, and esophageal cancer. The bibliometric analysis also indicated a growing trend of research focusing on the safety and complications of long-term PPI use. Conclusion: Long-term PPI therapy carries significant risks. Therefore, regular monitoring and appropriate discontinuation strategies are essential when using PPIs over extended periods to minimize potential harm.
Effectiveness of Clinical Pharmacy Interventions in Medication Adherence for Geriatric Patients: Literature Review Ilham, Febrian Dzikri; Hilmi, Indah Laily; Sudarjat, Hadi
Healthy Tadulako Journal (Jurnal Kesehatan Tadulako) Vol. 11 No. 2 (2025)
Publisher : Faculty of Medicine, Universitas Tadulako

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/htj.v11i2.1654

Abstract

Background: Medication adherence in geriatric patients is a major challenge as polypharmacy increases the risk of drug-related problems (DRPs). The role of clinical pharmacy is important in addressing these issues through evidence-based approaches. Objective: To review the effectiveness of various clinical pharmacy interventions in improving medication adherence in geriatric patients. Methods: This article used a systematic review of 13 literature selected from 934 articles based on inclusion criteria in the last 10 years, using PubMed and Google Scholar databases. The focus of the analysis included education, monitoring, and the use of tools such as pill cards and medication reminder charts. Results: Clinical pharmacy interventions, such as the use of Beers and STOPP/START criteria, counseling, and educational programs using tools, were shown to improve adherence in geriatric patients. Programs such as pill boxes increased adherence by 83.33%. However, some tools such as medication reminder charts had limited effectiveness. Conclusion: A collaborative approach, including patient and family education, monitoring, and clinical criteria-based therapy adjustments, is essential to improve medication adherence in geriatric patients, which directly improves their quality of life.
Literature Review: Pengaruh Efek Samping Obat Anti Tuberkulosis (OAT) Terhadap Kepatuhan Minum Obat Pasien Tuberkulosis di Indonesia: Literature Review: The Influence of Side Effect of Anti-Tuberculosis Drugs (Oats) on Drug Compliance of Tuberculosis Patients in Indonesia Hermawan, Deri; Hilmi, Indah Laily; Sudarjat, Hadi
Jurnal Surya Medika (JSM) Vol. 11 No. 2 (2025): Jurnal Surya Medika (JSM)
Publisher : Institute for Research and Community Services Universitas Muhammadiyah Palangkaraya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33084/jsm.v11i2.8554

Abstract

Agen infeksi yang menyebabkan Tuberkulosis (TB) masih menjadi salah satu masalah kesehatan terbesar di Indonesia adalah Mycobacterium tuberculosis. Faktor kunci dalam keberhasilan pengobatan tuberkulosis adalah komitmen pasien terhadap regimen terapi jangka panjang. Namun, kepatuhan pasien terhadap terapi sering kali sangat terhambat oleh adanya efek samping Obat Anti-Tuberkulosis (OAT). Tujuan penelitian ini untuk mengevaluasi dampak efek samping OAT terhadap kepatuhan pengobatan pada pasien tuberkulosis di Indonesia. Metode yang digunakan dalam pembuatan review artikel ini adalah literatur review dari sumber data sekunder Google Scholar dan Pubmed. Hasil penelitian ini menunjukkan efek samping Obat Anti-Tuberkulosis (OAT) yang paling sering terjadi adalah mual, muntah, nyeri sendi, gangguan pencernaan, dan perubahan warna pada urin berperan dalam kepatuhan minum obat pasien Tuberkulosis di Indonesia. Kesimpulan yang didapat, berdasarkan analisis terhadap 14 artikel, Semakin berat efek samping yang dialami, semakin rendah tingkat kepatuhan pasien terhadap pengobatan, sehingga diperlukan pemantauan terhadap pasien guna meningkatkan tingkat kepatuhan pengobatan Tuberkulosis di Indonesia.
DEVELOPMENT OF PLASMID-BASED FOR EXTERNAL CONTROL MATERIALS OF CYP2D6*10 (rs1065852) GENE PCR-BASED DETECTION Malau, Jekmal; Zahra, Aliya Azkia; Kasasiah, Ahsanal; Rahmasari, Ratika; Raekiansyah, Muhareva; Rohmah, Siti; Meilani, Nanda Diva; Septi, Annisa Frastica; Zahro, Aurora Fatimatuz; Annajla, Fathina; Hermosaningtyas, Anastasia Aliesa; Hilmi, Indah Laily
Jurnal Bioteknologi & Biosains Indonesia (JBBI) Vol. 10 No. 2 (2023)
Publisher : BRIN - Badan Riset dan Inovasi Nasional

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/jbbi.2023.2557

Abstract

Reliable clinical diagnosis of Single Nucleotide Polymorphisms (SNPs) is necessary for personalizing tamoxifen medication according to CYP2D6*10 genetic variations. Our research aimed to create a recombinant plasmid for external control material with a molecular size of 3812 bp. The recombinant plasmid was achieved by cloning an 838 bp gene insert of CYP2D6*10 rs1065852 into a 2974 bp pJET1.2 plasmid into Escherichia coli DH10B and selection on ampicillin agar medium. Isolated E. coli recombinants provided the plasmid molecules for analysis. Bi-directional sequencing and Real-Time PCR confirmed the presence of wild-type and mutant rs1065852 DNA fragments in the plasmid, namely homozygote CC and TT. The conclusion is that we have successfully introduced a novel recombinant plasmid developed by cloning the SNP rs1065852, which carries the 100C>T mutation, using pJET 1.2/blunt system, which could significantly enhance the accuracy of clinical SNP diagnostics for personalized medicine in breast cancer treatment.
Evaluasi Distribusi Produk Rantai Dingin pada Puskesmas di Kabupaten Karawang Komariah, Siti; Hilmi, Indah Laily; Ratnasari, Devi; Rachmawati, Ellin
JIK-JURNAL ILMU KESEHATAN Vol 6, No 2 (2022): JIK-Oktober Volume 6 Nomor 2 Tahun 2022
Publisher : UNIVERSITAS ALIFAH PADANG

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33757/jik.v6i2.537

Abstract

Menurut Badan Pengawas Obat dan Makanan No.9 tahun 2019 dalam setiap aspek dan rangkaian distribusi obat salah satunya pada produk rantai dingin. Produk rantai dingin merupakan obat yang labil, sensitif terhadap suhu perlu disimpan dalam lemari pendingin dengan suhu antara 2–8 C. Tujuan penelitian mengevalusi bagaimana operasional, personil/pelatihan dan bangunan/fasilitas, terhadap penerapan distribusi produk rantai dingin pada empat puskesmas di Kabupaten Karawang. Penelitian ini bersifat observasional  yang berbentuk deskriptif dengan pendekatan metode kualitatif. Pengambilan sampel dilakukan dengan menggunakan teknik purposive sampling. Semua kegiatan Alur distribusi pada puskesmas tersebut memiliki alur distribusi yang sama. Petugas penanggung jawab merupakan tenaga kesehatan yang telah mengikuti program pelatihan imunisasi, dari empat puskesmas 50 % masih belum memiliki bangunan dan ketidaksesuaian jarak/kondisi penyimapan dengan ketetapan standar. Kelengkapan alat penunjang dalam pengelolaan produk rantai dingin semua peralatan mematuhi seperangkat standar kinerja. Jadi, dari ke empat puskesmas yang berada di kabupaten karawang dengan presentase hasil nilai skala guttman yaitu 83,3 % efektif dalam pendistribusian, personil/petugas, pengelolaan produk rantai dingin vaksin dan juga setiap puskesmas dilengkapi oleh standar operasional prosedur. Pada puskemas untuk meningkatkan implementasi CDOB khususnya pengelolaan produk rantai dingin salah satunya pada aspek bangunan dan praktisi penanggung jawab.
Comparison of Varenicline’s Effectiveness with Nicotin Replacement Therapy (NRT) or A Combination of Both in Smoking Cessation: Literature Review Mahardika Urbaningrum, Lestari; Laily Hilmi, Indah
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (177.652 KB)

Abstract

Smoking is a cause of many chronic diseases such as lung cancer, oral cancer, to cardiovascular disease. Smoking addiction is caused by the nicotine in cigarettes. Thus Nicotine Replacement Therapy (NRT) was created as a substitute for nicotine consumption without smoking. While another drug that is widely prescribed is varenicline. However, varenicline is not yet available in Indonesia and the use of NRT is still very rare. Therefore, research is needed to compare the efficacy of the two. The research was conducted by studying the literature of international journals and obtained 12 journals that match the research title. As a result, varenicline monotherapy proved to be more effective than NRT or a combination of both.
The Dangerous Effects of Tramadol Abuse: Literature Review Prasetyo, Fajar; Indah Laily Hilmi
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (234.144 KB)

Abstract

Drug abuse is an act of using one or a combination of drugs in relatively high doses with the aim not for medication but to achieve a pleasure without regard to other aspects. Drug abuse can be motivated by several factors such as a weak personality, a high sense of curiosity, peer invitations, social problems and pressures, and the ease with which drugs can be obtained at low prices. One of the drugs that is often abused is tramadol. This is because tramadol can provide a euphoric effect. Without realizing it, tramadol abuse actually causes other, more dangerous effects. Therefore, writing this review article aims to provide an overview of other effects resulting from the abuse of tramadol drugs. The writing of this article review uses a systematic review method in which data is taken from national and international scientific articles or journals with a limitation of publication in the last 10 years. Articles obtained from searches using Google Scholar, PubMed, and Science Direct. From the results of the review, it is known that the misuse of tramadol drugs can be fatal because it can cause vomiting, seizures, sedation, and even death. Not only that, tramadol in high doses also affects fertility factors such as sperm defects and erectile dysfunction. Special attention is needed for cases of tramadol abuse because most of these activities are carried out by teenagers.
Literature Review The Effect Of Blood Supplements Tablet On Adolescent Girls In Anemia Alya Nafis; Indah Laily Hilmi
Jurnal EduHealth Vol. 13 No. 02 (2022): Jurnal eduHealth, Periode Oktober - December, 2022
Publisher : Sean Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (205.326 KB)

Abstract

According to data from Riset Kesehatan Dasar (Riskesdas) in 2018, the prevalence of anemia in Indonesia was 48.9%, with the highest prevalence of anemia at the age of 15-24 years and the least at the age of 45-54 years. Factors for the occurrence of iron nutritional anemia in adolescent girls include lack of education about iron nutritional anemia, unsupportive environmental factors, lack of attention to daily nutritional intake, and lack of implementation of preventive measures from the government by consuming blood-added tablets. This study uses the review article method with research data sources based on journal publications on the internet. Based on the results of the review article conducted, it can be concluded that the effect of giving blood-added tablets can increase hemoglobin (Hb) levels so as to avoid the incidence of anemia (Hb <12 mg/dL) and reduce the prevalence of anemia in Indonesia..
Co-Authors Adhwa'a Kaylla Adhwa'a Kaylla Affandhy Aditia Putra Tama Ahsanal Kasasiah Aisha K. Nur Aisiyah, Adella Aliya Azkia Zahra Alya Nafis Angga Prawira Kautsar Annajla, Fathina Annisa, Windy Aprida, Cantika Dewi Berliana Aryani, Ajeng Nita Audi Ichsani Ariwibowo Bunga Nur Annisa Cartas Cartas Cindhy Maulida Nurawaliah Dede Riyanto Devi Ratnasari Devi Ratnasari Deviana Farhani Dika Ramadhani Dinda Shafira Diniarti, Fuji Ayu Dytha Andri Deswati, Dytha Andri Ellin Rachmawati Ellin Rachmawati Fadya Laila Dzannuba Laila Dzannuba Fatharani, Adelia Firli Reisya Subekti Fitri Oktaviani Nurdin Fitri Otaviani Nurdin Fuji Ayu Diniarti Gun Gun Gumilar Gun Gun Gumilar Hadi Sudarjat Hajar Hartati Herdiana Verliani Herlaesa, Shofiatulfuadah Retnaningrum Hermawan, Deri Hermosaningtyas, Anastasia Aliesa Ibnu Mukti, Galih Ilham, Febrian Dzikri Imel Ramelia Hudaya Ineke Rossa Caroline Irene Virda Sakina Irvan Yoga Pardistya Irwansyah, Silvana Lestari Ita Novianti Izzati, Maulia Jahra Almas Shadrina Jahra Almas Shadrina Jaja Muhammad Zakaria Jasmine Rahma Saputri Jekmal Malau Jekmal Malau Lala Komala Sari Lely Sulfiani Saula Lestari, Sepiyani Ayu Maharani, Dhavina Mahardika Urbaningrum, Lestari Mally Ghinan Sholih Marisah Marisah Marsah Utami Maula, Kholida Atiyatul Meilani, Nanda Diva Mochammad Wahyudin Zarkasyi Muhammad Naufal Nurhadi Hidayat Muhammad Rizki Al Gibran Muhareva Raekiansyah Muini, Chantiara FM Mukarromah Dita Putri Munir Alinu Mulki MUTIARA ISKANDAR, PUTRI Nadia Andriani Nailuvar, Regita Nariyyah Fitriana Nico Nico Nisrina, Hasna Nurdin, Fitri Oktaviani Nurhafidah, Zahra Nurlaela Nurlaela Oktavianti, Alfina Piantara, Seia Piantara Prasetyo, Fajar Puteri Rahma Maharani Putria, Devy Kasih Rachmawati, Ellin Rahmasari, Ratika Rahmi Indian Rahmi Indiani Rahmi Zubaedah Rahmi Zubaidah Ratnasari, Devi Rima Putri Ramadhani Rizky Abdulah Salman Salman Salman Salman Salman Salman Salsabila, Isyana salsabilla, Diva rizqi Sekar Ayu Maharani Septi, Annisa Frastica Septiani, Dia Shalum Putriyani Sholih, Mally Ghinan Siti Komariah Siti Rohmah Sophy Wulandari Sophy Wulandari Sridevi Anggraini Sudarjat, Hadi Sulastri Sulastri Supryatno, Adi Triana Maudy Yulianti Surasa Tsani Arsy Mura Valensia, Rika Vina Luthfiana Hasna Wahyudin Wahyudin Wardani, Aulia Wildani Zakiyah Windari, Welly Wulandari, Yulia Eka Yuli Yuliani Yulianti Surasa, Triana Maudy Yuniar Fathil Ilmi Zahra Nurhafidah Zahra, Aliya Azkia Zahro, Aurora Fatimatuz