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All Journal Jurnal Entropi Sainstek AKADEMIKA Biology, Medicine, & Natural Product Chemistry Jurnal Penelitian Sains JURNAL PENDIDIKAN GLASSER Jurnal Pendidikan Kimia (JPKim) Indonesian Journal of Chemistry Indonesian Journal of Pure and Applied Chemistry Chemistry Indonesian Journal of Chemical Research Dalton : Jurnal Pendidikan Kimia dan Ilmu Kimia Jambura FIsh Processing Journal Jambura Journal of Educational Chemistry Jambura Journal of Chemistry Jurnal Riset Pendidikan Kimia (JRPK) Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Stannum : Jurnal Sains dan Terapan Kimia SPIN: Jurnal Kimia & Pendidikan Kimia Jurnal Kolaboratif Sains CHEDS: Journal of Chemistry, Education, and Science Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Pentagon: Jurnal Matematika dan Ilmu Pengetahuan Alam Damhil: Jurnal Pengabdian kepada Masyarakat Journal of Community Services on Multidisciplinary Sciences Jurnal Pendidikan Kimia, Fisika dan Biologi Konstanta : Jurnal Matematika dan Ilmu Pengelatuan Alam
Nurhayati Bialangi
Universitas Negeri Gorontalo
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Civil Engineering, Building, Construction & Architecture Computer Science & IT Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Industrial & Manufacturing Engineering Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Nursing Physics Public Health Other

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Deskripsi Kemampuan Pemecahan Masalah Siswa pada Materi Hidrolisis Garam Bialangi, Nurhayati; Paputungan, Fadilah Alawiya; Paputungan, Mardjan; Suleman, Nita; Arviani, Arviani; Kurniawati, Erga
Jambura Journal of Educational Chemistry Vol 5, No 1 (2023): February
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/jjec.v5i1.14863

Abstract

Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Instrument yang digunakan adalah tes esai pada materi hidrolisis garam. Sampel dalam penelitian ini adalah 40 orang siswa SMA Negeri 4 Gorontalo. Hasil penelitian menunjukkan bahwa hasil persentase rata-rata dari keseluruhan butir soal yaitu sebesar 45% termasuk kedalam kategori cukup. Kemampuan pemecahan masalah siswa pada tahap memahami masalah sebesar 53.50% termasuk kedalam kategori cukup. Kemampuan pemecahan siswa pada tahap merencanakan pemecahan masalah sebesar 50.75% termasuk kedalam kategori cukup. Kemampuan pemecahan masalah siswa pada tahap melaksanakan rencana penyelesaian sebesar 46.67% termasuk kedalam kategori cukup. Kemampuan pemecahan masalah siswa pada tahap memeriksa kembali jawaban yang diperoleh sebesar 24% termasuk kedalam kategori kurang.
Analisis Kemampuan Berpikir Kreatif Siswa pada Materi Sel Volta dan Sel Elektrolisis dengan Menggunakan Tes Open-Ended Problem Mohamad, Erni; Iyabu, Hendri; Wiwiyani, Wiwiyani; Sihaloho, Mangara; Bialangi, Nurhayati; Kilo, Akram La
Jambura Journal of Educational Chemistry Vol 5, No 2 (2023): August
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/jjec.v5i2.14492

Abstract

This study aims to determine students' creative thinking abilities in the topics of voltaic cells and electrolysis by using open-ended problem tests at SMA Negeri 4 Gorontalo, to understand teachers' responses to the administered open-ended problem tests, and to gauge students' responses to the administered open-ended problem tests. The research approach employed is descriptive qualitative. The subjects of this study were 62 twelfth-grade science students and 2 chemistry teachers at SMA Negeri 4 Gorontalo. The data utilized in the study consist of the results of students' creative thinking ability tests using open-ended problem tests, as well as the responses gathered from questionnaires regarding the test item model. The research findings reveal that students' creative thinking abilities in terms of fluency aspect are at 47.8% categorized as moderately creative, the flexibility aspect at 45.4% categorized as moderately creative, and the originality aspect at 31.9% categorized as less creative. The results from the teachers' questionnaire responses regarding the open-ended problem test model show a positive response rate of 80%, while the results from the students' questionnaire responses indicate a positive response rate of 61%.
Analisis Pemahaman Konsep Siswa pada Materi Stoikiometri Menggunakan Tes Diagnostik Lima Tingkat di SMA Negeri 4 Gorontalo Miftahul Nur; Nurhayati Bialangi; Julhim S. Tangio; Erni Mohamad; Erga Kurniawati; Astin Lukum
Konstanta : Jurnal Matematika dan Ilmu Pengetahuan Alam Vol. 2 No. 4 (2024): Desember : Jurnal Matematika dan Ilmu Pengetahuan Alam
Publisher : International Forum of Researchers and Lecturers

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59581/konstanta.v2i4.4393

Abstract

The principles of chemistry learning emphasize that students study chemical concept in a structure and detailed manner. Until now, chemistry lessons are still a big challenge for teachers, because students often experience difficulties when learning chemical concept such as the concept of stoichiometry. This study aims to determine the level of concept understanding and the percentage of students' concept understanding on stoichiometry material using a five tier diagnostic test. The method used in this research is descriptive qualitative. The results showed: (1) the average level of students' concept understanding is classified in the category of lack of knowledge (LK); (2) the average percentage of students who understand the concept (SC) is 13.0% and the sub-concept with the highest percentage of understanding the concept (SC) is Relative Molecular Mass which is 33.0%. Of the 15 questions tested, question number 1 has the highest percentage of understanding the concept (SC) of 33.0%, while for the other 14 questions the average student is classified in the category of lack of knowledge (LK). It can be concluded that students' concept understanding on stoichiometry material is still classified as very low criteria.
PENGARUH PENAMBAHAN KOAGULAN BIJI KELOR TERHADAP PENURUNAN KADAR LOGAM KROMIUM (Cr), MANGAN (Mn), DAN TIMBAL (Pb) MENGGUNAKAN ICP-OES (THE ADDITION EFFECT OF KELOR SEEDS COAGULANT ON THE DECREASING OF CHROMIUM (Cr), MANGANESE (Mn), AND LEAD (Pb) LEVELS USING ICP-OES) Susvira, Dian; Ramadhan, Muhammad Bagus; Susparini, Ninik Triayu; Situmeang, Boima; Widiyanto, Holisha; Bialangi, Nurhayati; Musa, Weny JA
Indonesian Journal of Pure and Applied Chemistry Vol 7, No 1 (2024)
Publisher : Tanjungpura University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.26418/indonesian.v7i1.63599

Abstract

Electroplating process has a negative effect in form metal ions waste. Today, industrial wastewater treatment widely using aluminum sulfate or alum as synthetic coagulants, although hazardous and expensive. This study was conducted to discover the activity of Moringa seeds (Moringa oleifera) as natural coagulants to substitute synthetic coagulants. Trapped metal ions detected by ICP-OES. The results showed that moringa seed coagulants could reduce 53% Cr, 64.56% Mn, and 92.89% Pb in the addition of 15 grams of moringa seed coagulants.
AKTIVITAS PENURUN KOLESTEROL DARI EKSTRAK N-HEKSANA DAUN BIDARA (ZIZIPHUS MAURITIANA) Lailatusholihah, Isna; Setyoko, Lintang Panji; Wijayanti, Sri; Situmeang, Boima; Musa, Weny JA; Bialangi, Nurhayati
CHEDS: Journal of Chemistry, Education, and Science Vol 7, No 2 (2023)
Publisher : Universitas Islam Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30743/cheds.v7i2.8398

Abstract

Kolesterol, lipid penting untuk proses metabolisme, memegang peran penting dalam tubuh manusia. Namun, kelebihan kolesterol berpotensi menghambat fungsi otak secara optimal. Penelitian ini berupaya untuk meneliti ekstrak daun bidara, menggunakan pelarut n-heksana, dengan tujuan khusus untuk menilai kemanjurannya dalam mengurangi kadar kolesterol. Analisis fitokimia daun bidara mengetahui adanya alkaloid, steroid, dan tanin. Khususnya, kandungan senyawa fenolik yang melekat pada daun bidara muncul sebagai kandidat yang menjanjikan sebagai agen anti kolesterol. Temuan empiris ini memperkuat kemanjuran ekstrak daun bidara, yang memanfaatkan pelarut n-heksana, dalam menurunkan kadar kolesterol sebesar 70,4023%.
Peningkatan Kesadaran Masyarakat terhadap Bahaya Penggunaan Zat Aditif dalam Makanan Bialangi, Nurhayati; Musa, Weny J.A; Kilo, Ahmad Kadir; Kurniawati, Erga; Thayban, Thayban
Damhil: Jurnal Pengabdian kepada Masyarakat Vol 2, No 2: December 2023
Publisher : Universitas Negeri Gorontalo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34312/damhil.v2i2.24442

Abstract

Education on the dangers of using food additives is an effort to enhance the public's understanding of the risks associated with consuming foods containing additives. The increased consumption of additives correlates with the rising intake of processed foods. The objective of this community engagement initiative is to raise awareness among the public regarding the potential hazards associated with the use of food additives. The methods employed include lecture-style presentations and discussions. The community gains an understanding of various types of additives commonly used in food, with an emphasis on their benefits, such as prolonging the shelf life of food. However, the education also highlights associated risks, including potential adverse effects on health like allergies, digestive disorders, and long-term effects that are not fully understood. The activities took place in the village of Hutadaa in Gorontalo Regency, with a total of 18 participants. The participants were enthusiastic, and increased knowledge was evident through the questions raised during the session.
IDENTIFIKASI TURUNAN ASAM KARBOKSILAT AKAR Acalypha indica SEBAGAI KANDIDAT INHIBITOR GFAT MELALUI LC-HRMS DAN STUDI IN SILICO Arviani; K. Salimi, Yuszda; Bialangi, Nurhayati; Chandra Lakasan, Ahmad; Nur Rahman, Zifran
Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan Vol 11 No 1 (2026): Jurnal Ilmiah Ibnu Sina
Publisher : Sekolah Tinggi Ilmu Kesehatan ISFI Banjarmasin

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36387/jiis.v11i1.2828

Abstract

Diabetes mellitus remains a major global health challenge, prompting the exploration of natural products as sources of safer antidiabetic agents. This study aimed to identify bioactive compounds from the roots of Acalypha indica and evaluate their potential as inhibitors of glutamine–fructose-6-phosphate amidotransferase (GFAT), an enzyme involved in glucose metabolism. Compound profiling was conducted using liquid chromatography–high resolution mass spectrometry (LC-HRMS), while the inhibitory potential against GFAT was assessed through in silico docking. This integrated approach has not been previously reported. Metabolite profiling using LC-HRMS tentatively identified thirteen carboxylic acid derivatives, including hydroxycinnamic acid, gluconic acid, trans-aconitic acid, and glucoheptonic acid. molecular docking analysis revealed strong binding affinities of several compounds toward GFAT.  Glucoheptonic acid exhibited the lowest binding energy (−8.0 kcal/mol), followed by xylaric acid A (−7.9 kcal/mol) and trans-aconitic acid (−7.5 kcal/mol). These compounds interacted with key active-site residues Gln421, Ser420, Ser422, and Lys675, suggesting a potential enzyme inhibition mechanism. In silico pharmacokinetic analysis indicated that 2-hexylpentanedioic acid exhibited favorable ADME properties, with high gastrointestinal absorption, no major inhibition of CYP450, and low predicted acute toxicity risk. These findings highlight Acalypha indica roots as a promising source of bioactive carboxylic acid derivatives, with glucoheptonic acid emerging as the most promising candidate for further in vitro evaluation as a GFAT inhibitor
Antioxidant and Antibacterial Properties of Methanol Extract of Gletang Flower (Tridax procumbens) Boima Situmeang; Weny JA Musa; Nurhayati Bialangi; Sriwijayanti Sriwijayanti; Holisha Widiyanto; Dian Susvira
Biology, Medicine, & Natural Product Chemistry Vol 14, No 2 (2025)
Publisher : Sunan Kalijaga State Islamic University & Society for Indonesian Biodiversity

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14421/biomedich.2025.142.1085-1090

Abstract

In a previous study, the methanol extract of Tridax procumbens flowers (commonly known as gletang) at high concentrations was reported to exhibit strong antibacterial activity against Streptococcus mutans and Enterococcus faecalis. This study aimed to examine the secondary metabolite content, antioxidant activity, and antibacterial activity of the methanol extract of gletang flowers. The antioxidant activity was evaluated using two methods, namely DPPH and ABTS assays. The antibacterial activity was assessed using the Kirby-Bauer method at concentrations of 1000, 5000, and 10000 ppm against Staphylococcus aureus, Escherichia coli, Streptococcus mutans, and Enterococcus faecalis. Phytochemical screening revealed that the methanol extract of gletang flowers contains phenolic compounds, flavonoids, alkaloids, and triterpenoids. The antioxidant activity tests showed very strong activity in both DPPH and ABTS assays, with IC50 values of 6.8478 ± 1.335 and 12.8608 ± 0.579 ppm, respectively. The antibacterial activity tests showed that the methanol extract of gletang flowers exhibited strong activity against E. faecalis at concentrations of 5000 and 10000 ppm, with inhibition zone diameters of 3.00 ± 0.14 and 3.20 ± 0.14 mm, respectively.
AKTIVITAS ANTIOKSIDAN HIDROLISAT PROTEIN TULANG IKAN SELAR BENTONG (Selar Crumenophthalmus) HASIL HIDROLISIS ENZIM PAPAIN Fitri Hadji; Deasy N. Botutihe; Najmah Najmah; Nurhayati Bialangi; Wiwin Rewini Kunusa
Jurnal Crystal : Publikasi Penelitian Kimia dan Terapannya Vol. 7 No. 2 (2025): Literasi Artikel Penelitian Kimia
Publisher : Program Studi Kimia, Fakultas MIPA, Universitas PGRI Banyuwangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36526/jc.v7i2.6186

Abstract

Ikan selar bentong (Selar crumenophthalmus) merupakan salah satu ikan pelagis kecil yang banyak terdapat di perairan Gorontalo dan memiliki nilai ekonomis penting. Hasil perikanan samping berupa tulang ikan masih jarang dimanfaatkan, meskipun kandungan proteinnya cukup tinggi dan berpotensi menghasilkan produk bernilai fungsional. Penelitian ini bertujuan untuk mengkarakterisasi hidrolisat protein tulang ikan selar bentong serta mengaktifkan aktivitas antioksidannya. Hidrolisis dilakukan menggunakan enzim papain dengan konsentrasi 2%, 4%, dan 6% selama 4 jam pada kondisi optimal. Parameter yang dianalisis meliputi kadar protein, derajat hidrolisis, uji kualitatif asam amino, serta aktivitas antioksidan menggunakan metode ABTS. Hasil penelitian menunjukkan bahwa kadar protein tulang ikan meningkat dari 10,47% pada kondisi mentah menjadi 33,19% pada konsentrasi enzim 2%, 35,08% pada konsentrasi 4%, dan 37,35% pada konsentrasi 6%. Nilai derajat hidrolisis juga meningkat dengan penambahan enzim, dengan nilai tertinggi 83,16% pada konsentrasi 6%. Aktivitas antioksidan terbaik ditunjukkan pada konsentrasi enzim 6% dengan nilai IC50 sebesar 0,98 mg/mL, mendekati vitamin C (0,12 mg/mL). Simpulan dari penelitian ini adalah hidrolisat protein tulang ikan selar bentong berpotensi sebagai sumber antioksidan alami yang dapat diterapkan dalam pengembangan fungsional pangan maupun suplemen kesehatan. Kata kunci : ikan selar bentong, protein hidrolisat, papain, antioksidan, ABTS
Co-Authors Agus Malik Ibrahim Ahmad Kadir Kilo Ahmad, Halid S. Akram La Kilo Anggraini Dj Usman Ari Widiantoro Ari Widiyantoro Arviani Arviani Arviani Astin Lukum Boima Ramses Situmeang Boima Situmeang Boima Situmeang Boima Situmeang Chandra Lakasan, Ahmad Deasy N. Botutihe Deasy Natalia Botutihe Dian Susvira Diky Kurniawan Djalil, Jhodi Pratama Djalil, Moh. Rifaldi Eka Puspita Sari Erga Kurniawati Erni Mohamad Faradin, Faradin Fauziah, Eka Donna Fitri Hadji giu, fitri ani Halalutu, Hamdan Halalutu, Hamdan Haleda, Padria Haris Munandar Hendri Iyabu Hidayatullah, Ryan Holisha Widiyanto Holisha Widiyanto Ibrahim, Agus Malik Ibrahim, Agus Malik Ishak Isa Isna Lailatusholihah Jafar La Kilo Jinanti, Nazwa Julhim S Tangio Julhim S Tangio Julhim S. Tangio Julinton Sianturi Jumarni Kamarudin K. Salimi, Yuszda Kupang, Sri Revayana La Alio La Alio La Ode Aman Lailatusholihah, Isna Lailatussholihah, Isna Laliyo, Lukman Lintang Panji Setyoko Lintong, Kristin Lisdawati N. Umar Lukman A. R. Laliyo M Amrin Sunardi Mangara Sihaloho Mardjan Paputungan Marsya Divya Olii Masrid Pikoli Meli A. Rasid Miftahul Nur Moh Adam Mustapa Mohamad Adam Mustapa Muhridja, Melisa Mulyadi, Agus Musa, Weni J.A Musa, Weny J.A. Mustafid, Afif Hidayatul Najmah Najmah Nani Yulianti Netty Ino Ischak Ngabito, Putri Amalia Nilda Apriyati Tengo Ninik Triayu Susparini, Ninik Triayu Nita Suleman Nona Wingti Posangi Nur Rafida Akub Nur Rahman, Zifran Nur Riska Apriana Nur, Dian Nurfadilah M. Kasim Nurkhaliq, Nurkhaliq Nurlaela Abd. Kadir Ode, Nur Mei Yulianty Olii, Marsya Divya Pakaya, Agustina H. Paputungan, Fadilah Alawiya Parulian, Boima Ramses Perry Zakaria R Tulie, Wina Zulviana Ramadhan, Muhammad Bagus Reski Rahmatia Idris Rifki Brahmono Idrus Risnayanti R Juramang Rustam I. Husain Sahami, Ulin Saiman Saiman Samosir, Andeston Sumandoli Saronom Silaban Setiyandani, Kurnia Indah Setyoko, Lintang Panji Situmeang, Boima Sri Wijayanti Sriwijayanti Sriwijayanti Sriwijayanti Sriwijayanti Stasya Anggriani Talib Suleman Duengo Sumarlin Soleman Susparini, Ninik Triayu Susvira, Dian Thayban, Thayban Wenny J A Musa Weny J.A Musa Weny J.A Musa Weny JA Musa Weny Musa Widiyanto, Holisha Widy Susanti Abdulkadir Wiwin Rewini Kunusa Wiwiyani, Wiwiyani Yayurulia Hadju Yuliana Retnowati Yusuf, Risciana Yuszda K Salimi Yuszda K. Salimi Yuzda K Salimi