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All Journal Mechatronics, Electrical Power, and Vehicular Technology JURNAL TEKNOLOGI LINGKUNGAN Abdimas Medical Journal of Indonesia CHEMPUBLISH JOURNAL Universa Medicina Jurnal Kreativitas PKM Jurnal Respirologi Indonesia Jurnal Respirasi (JR) Community Development Journal: Jurnal Pengabdian Masyarakat Jurnal Informa: Jurnal Penelitian dan Pengabdian Masyarakat Jurasik (Jurnal Riset Sistem Informasi dan Teknik Informatika) Jurnal Pendidikan Guru Jurnal Farmasi dan Sains Indonesia (JFSI) JOURNAL LA MEDIHEALTICO Jurnal Pengabdian Masyarakat (ABDIRA) Innovative: Journal Of Social Science Research Musyarakah: Journal of Sharia Economics (MJSE) Accounting Analysis Journal Jurnal Sains dan Kesehatan Jurnal Ilmiah Nusantara Research In Management and Accounting (RIMA) Toga Jurnal Keguruan dan Ilmu Pendidikan Preventif : Jurnal Kesehatan Masyarakat
Arif Santoso
Research Center for Electrical Power and Mechatronics, Indonesian Institute of Sciences, Komp. LIPI Bandung, Jl. Sangkuriang, Gd. 20. Lt. 2, Bandung 40135
Religion Aerospace Engineering Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Electrical & Electronics Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Veterinary Other

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Pengaruh Pemberian Terapi Komplementer Jinten Hitam (Nigella sativa) terhadap Kadar SGPT Pada Pasien Hipertensi di Desa Sodo Kecamatan Pakel: Effect of Black Cumin Compementary (Nigella sativa) on SGPT Levels Hypertensive Patiens at Sodo Village, Pakel District Khakim, Lukmanul; Santoso, Arif; Martha, Rahma Diyan; Huda, Choirul; Muadhifah, Afidatul
Jurnal Sains dan Kesehatan Vol. 6 No. 3 (2024): J. Sains Kes.
Publisher : Fakultas Farmasi, Universitas Mulawarman, Samarinda, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25026/jsk.v6i3.2174

Abstract

Hypertension is a disease that requires long-term medical therapy. Among the complications caused by hypertension is fatty liver. The aim of this research was to determine the effect of complementary administration of black cumin (nigella sativa) on SGPT levels. The experimental research method uses Randomized Controlled Trial (RCT). Randomization of samples used a random sampling method and patients with a diagnosis of hypertension were divided into two groups. The control group was given placebo therapy 2x2 capsules a day, while the treatment group was given black cumin capsule therapy 2x2 capsules a day. This research was carried out for 30 days by measuring SGPT levels on days 0 and 31. The results of sociodemographic data analysis show that hypertension sufferers are more likely to be in the age range 55-65 years, female gender, primary school education, work as a housewife, suffering < 2 years, the most common comorbidity is hypercholesterolemia, more often have no history of hypertension, more people consume medication but not routinely. Changes in SGPT levels in hypertensive patients in the control group showed an average decrease of 0.60 U/L P-value 0.280 and the treatment group showed an average decrease of 0.65 U/L P-value 0.719. The independent T-test between the control group and the treatment group showed that there was no significant difference in the effect of using black cumin with a P-value of 0.600. This shows that giving black cumin capsules is safe for use in the liver of hypertensive patients. Keywords:          Hypertension, SGPT levels, Black Cumin, Hepatoprotector   Abstrak Hipertensi penyakit yang membutuhkan terapi pengobatan dalam jangka panjang. Diantara komplikasi yang disebabkan oleh penyakit hipertensi adalah perlemakan hati. Tujuan dari penelitian ini untuk mengetahui bagaimana pengaruh pemberian  komplementer  jinten hitam (nigella sativa ) terhadap  kadar SGPT. Metode penelitian eksperimetal menggunakan Randomized Controlled Trial (RCT). Pengacakan sampel menggunakan metode sample random sampling dan pasien dengan diagnosis hipertensi dibagi mejadi dua kelompok. Kelompok kontrol diberi terapi plasebo 2x2 kapsul sehari, sedangkan kelompok perlakuan diberi terapi kapsul  jinten hitam 2x2 kapsul sehari. Penelitian ini dilakukan selama 30-hari  dengan mengukur kadar SGPT pada hari ke-0 dan dan ke-31. Hasil analisis data sosiodemografi penderita hipertensi lebih banyak pada rentang usia 55-65 tahun, jenis kelamin perempuan, pendidikan terakhir SD, pekerjaan sebagai IRT, lama menderita < 2 tahun, penyakit penyerta terbanyak hiperkolesterolemia, lebih banyak tidak terdapat riwayat hipertensi, lebih banyak mengkonsumsi obat namun tidak rutin. Perubahan kadar SGPT pasien hipertensi kelompok kontrol menunjukan nilai rata-rata penurunan 0,60 U/L P-value 0,280 dan kelompok perlakuan menunjukan nilai rata-rata penurunan 0,65 U/L  P-value 0,719. Independent T-test antara kelompok kontrol dan kelompok perlakuan menunjukan tidak ada perbedaan pengaruh penggunaan jinten hitam signifikan dengan nilai P-value 0,600. Hal ini menunjukan bahwa pemberian kapsul jinten hitam aman digunakan terhadap hati pasien hipertensi. Kata Kunci:         Hipertensi, kadar SGPT, Jinten Hitam, Hepatoprotetektor
Peran Perusahaan Jasa Tenaga Kerja Indonesia Dalam Meningkatkan Ekonomi Masyarakat Menurut Perspektif Ekonomi Syariah Rois, Adib Khusnul; Santoso, Arif; Syukroni, Azid; Candrakusuma, Muslih
Musyarakah: Journal of Sharia Economic (MJSE) Vol 4, No 2 (2024): October
Publisher : Universitas Muhammadiyah Ponorogo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24269/mjse.v4i2.8789

Abstract

Indonesian Employment Services Companies can play an important role in improving the community's economy, especially from a sharia economic perspective. From a sharia economic perspective, this is very important because investment in human resources is considered a better investment than investment in goods and capital. By improving the quality of the workforce, the Indonesian Employment Services Company can make a greater contribution in developing more productive economic sectors, such as the service and industrial sectors. By paying attention to these aspects, the Indonesian Employment Services Company can help build a more inclusive, fair and sustainable economy, which is in line with sharia economic goals. This research was conducted with the aim of, first. To find out the role of Private Indonesian Migrant Worker Placement Implementers in sending Indonesian Migrant Workers abroad which includes the recruitment process, provision, departure and working relationships with agents abroad. Second. To find out the role of the Indonesian Employment Services Company in improving the economy of the study community at the Mulia Laksana Sejahtera Limited Liability Company, Ponorogo Branch. The results of this research, first, are that Private Indonesian Worker Placement Implementers have an important role in providing employment opportunities through sending Indonesian Workers abroad. The Implementer of Private Indonesian Worker Placement is responsible for carrying out good recruitment, providing provision and training, ensuring safe and legal departure, as well as protecting and paying attention to the welfare of Indonesian Workers. Second, the mechanism for improving the community's economy through Indonesian workers can be carried out by prioritizing income and remittances for Indonesian workers obtained through work that is halal and in accordance with sharia principles. Returning Indonesian workers can strengthen the sharia economy with sharia businesses that will strengthen the halal sector and create jobs in accordance with sharia principles.
The Role of Genome-Wide Association Study in Pulmonary Disease Diagnostics: A Review in Medical Bioinformatics Andromeda, Rossalyn; Pratomo, Irandi Putra; Fauzi, Ahmad; Kinasih, Tutug; Prasenohadi, Prasenohadi; Santoso, Arif; Tokumo, Kentaro
Jurnal Respirasi Vol. 10 No. 1 (2024): January 2024
Publisher : Faculty of Medicine Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/jr.v10-I.1.2024.76-84

Abstract

Biomedical science, which initially required only conventional research in the laboratory, currently involves information technology and has created bioinformatics in its development. Bioinformatics, a branch of biology, quantitatively analyzes information within biological macromolecules using software. Contemporary applications of bioinformatics have advanced biotechnological, medical, and pharmaceutical practices. Among the established applications of bioinformatics is diagnosing lung diseases using the genome-wide association study (GWAS) technique. Owing to sequencing technology and rapid computational methods, this technique is applied to analyze the link between genes with essential traits in the population, thus mapping the target genes to diagnose and treat diseases. The lung diseases diagnosed using GWAS include the responsible locus in asthma, chronic obstructive pulmonary disease (COPD), and lung cancer. Moreover, it can identify the treatment for COPD and suggest a new locus in lung cancer. Advancing the current gene-mapping technology demands genotype and phenotype data to study disease-linked genomes. Currently, bioinformatics is barely known and receives little attention in Indonesia. However, it can grow rapidly through open-source basis data and cross-disciplinary collaboration.
Persistent Air Leak Anggita, Dwi; Wiriansya, Edward Pandu; Santoso, Arif; Putrawan, Harry Azka
Jurnal Respirologi Indonesia Vol 44 No 2 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i2.432

Abstract

In cases of pneumothorax in the chest tube, the presence of air in the pleural cavity that lasts more than 5 to 7 days can be suspected as a persistent air leak (PAL), especially if an increased amount of air is obtained accompanied by the appearance of bubbles in the water seal drainage (WSD) system. This is the most common complication after surgery (8–26%), although it can be primary spontaneous pneumothorax (PSP) (26%) or secondary spontaneous pneumothorax (SSP) (39%). One condition that often causes difficulties in PAL therapy is infection due to direct contact with the fistula. The presence of PAL is associated with higher morbidity and mortality, prolonged chest tube inserted, and longer hospitalization. Observations of air production in PAL are expected to occur spontaneously within 4 days, if the leak persists, pleurodesis is recommended. If it was possible, surgery is needed to close the leak. Bronchoscopy treatment is only recommended in special circumstances where surgery is contraindicated or the patient refuses the surgical procedure.
Indonesian Society of Respirology Position Paper on Lung Cancer Control in Indonesia Andarini, Sita; Santoso, Andintia Aisyah; Arfiansyah, Mochammad Aris; Syahruddin, Elisna; Zaini, Jamal; Putra, Andika Chandra; Kurniawan, Ferry Dwi; Ermayanti, Sabrina; Soeroso, Noni Novisari; Munir, Sri Melati; Infianto, Andreas; Setijadi, Ana Rima; Setyawan, Ungky Agus; Wulandari, Laksmi; Haryati, Haryati; Jasminarti, Ida Ayu; Hidayat, Moulid; Santoso, Arif
Jurnal Respirologi Indonesia Vol 44 No 4 (2024)
Publisher : Perhimpunan Dokter Paru Indonesia (PDPI)/The Indonesian Society of Respirology (ISR)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36497/jri.v44i4.884

Abstract

Lung cancer is a major health concern in Indonesia due to its increasing prevalence, late-stage diagnosis, younger population, and high mortality. Addressing this issue requires nationwide implementation of comprehensive lung cancer control, which includes risk reduction and prevention strategies, focusing on tobacco control and air pollution mitigation. Screening with low-dose computed tomography (LDCT) and early detection in symptomatic patients, along with TB screening programs and all non-communicable diseases, is strongly recommended to enhance early case findings, treatment effectiveness, and overall patient outcomes. A multidisciplinary team (MDT) approach is important to ensure accurate diagnosis and comprehensive care. Moreover, the integration of palliative care at the early stages of advanced lung cancer is vital, focusing on symptom management and enhancing the quality of life for patients. While national guidelines are available for the diagnosis and treatment of lung cancer, significant disparities in healthcare access remain across Indonesia. Thus, it is essential to improve universal health coverage and referral systems to guarantee equal access to lung cancer care for patients at all levels through advocacy and ease of access.
UPAYA PENINGKATAN PERILAKU PENCEGAHAN DAN PENGENDALIAN PENYAKIT DHF UNTUK MENDUKUNG PROGRAM KESMAS DI DESA TANGGUNGGUNUNG Nurjanah, Mutia Hariani; Kumalasari, Nurul Chamidah; Safitri, Yunita Diyah; Martha, Rahma Diyan; Santoso, Arif; Muadifah, Afidatul; Imanez, Ketzia Adrian
Community Development Journal : Jurnal Pengabdian Masyarakat Vol. 5 No. 5 (2024): Vol. 5 No. 5 Tahun 2024
Publisher : Universitas Pahlawan Tuanku Tambusai

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31004/cdj.v5i5.34405

Abstract

Dengue haemoragic fever (DHF) nama lain demam berdarah merupakan infeksi virus yang ditularkan melalui gigitan nyamuk Aedes albopictus dan Aedes aegypti. Demam berdarah telah meningkat secara signifikan dalam dekade terakhir seiring dengan pergerakan manusia, peningkatan populasi, dan terjadinya perubahan iklim. Di Indonesia, penyakit DHF mendapat perhatian serius dari seorang pakar kesehatan masyarakat, dimana beliau menjelaskan cara mencegah penularan dengan pendekatan yang efektif dan efisien. Tujuan diadakannya kegiatan kesehatan masyarakat ini ialah memberikan edukasi kepada masyarakat terkait pencegahan penyakit DHF yang disebabkan oleh gigitan nyamuk yang mengandung virus dengue. Hasil yang diperoleh dari kegitan ini adalah dengan cara menjaga lingkungan, menjaga imunitas, perilaku preventif dan pengendalian vector demam berdarah. Kesimpulan dari pengmas ini adalah adanya peningkatan pengetahuan dan pemahaman masyarakat desa Tanggunggunung yang baik dalam upaya mencegah penyakit DHF.
President Commissioner Attributes and Climate Change Disclosure: Evidence from Indonesian Banking Companies Susilowati, Nurdian; Mahmud, Amir; Santoso, Arif; Sari, Puji Novita; Lestari, Sari
Accounting Analysis Journal Vol. 13 No. 2 (2024)
Publisher : Universitas Negeri Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/aaj.v13i2.7836

Abstract

In recent years, there has been an increased demand for information regarding companies’ risk management efforts and opportunities related to climate change. The lack of concrete evidence about companies’ efforts to address the impacts of climate change highlights the importance of climate change disclosure. The purpose of this study is to examine the influence of the attributes of the president commissioners (gender, age, and nationality) on climate change disclosure. Method: The study focuses on listed entities within the banking sector from 2020 to 2022 using a quantitative research methodology. The purposive sampling technique was used to gather a sample size of 129 observations. The data was analyzed using Stata 16. Findings: The results indicate that companies with female president commissioners tend to disclose less about climate change, while age and foreign nationality positively impact disclosure. These findings align with the upper-echelon theory and have significant practical implications. They underscore the need for policymakers to consider the president commissioner’s characteristics when developing strategies to promote climate change disclosure, given the growing importance of sustainability concerns. The robustness checks on the regression results consistently support these findings. Novelty: The president commissioner plays a crucial role in determining the success of climate change disclosure. Previous studies have analyzed commissioners’ educational backgrounds, while other crucial traits for supporting climate change disclosure, such as gender, age, and nationality, still lack empirical evidence. Additionally, there is still little attention given to the banking industry.
Syndecan-4 levels in bronchoalveolar lavage fluid and serum in non-small cell lung cancer Abdul Azis, Asrul; Santoso, Arif; Djaharuddin, Irawaty; Iskandar, Harun; Ilyas, Muhammad; Lihawa, Nurjannah
Medical Journal of Indonesia Vol. 33 No. 2 (2024): June
Publisher : Faculty of Medicine Universitas Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.13181/mji.oa.247264

Abstract

BACKGROUND Lung cancer has the highest cancer-related mortality rate worldwide. Research has been conducted to improve early detection and markers of predictive value but only focused on the expression of syndecan-4 (SDC4) in serum. Studies in bronchoalveolar lavage (BAL) fluids of non-small cell lung cancer (NSCLC) patients are still limited. This study aimed to evaluate the clinical value of SDC4 in serum and BAL in NSCLC patients. METHODS Blood serum and BAL fluids were obtained from 44 patients with NSCLC and 41 non-cancer patients as the control. The level of SDC4 was measured. The relationships between SDC4 and clinicopathologic factors were also analyzed. RESULTS Serum SDC4 levels in NSCLC patients were significantly lower than the control group (p = 0.002). Furthermore, the disease stages and serum SDC4 levels had a negative correlation, which was lower in the advanced stage (IIIb/IV) than in the initial stage (I/II/IIIa) (p = 0.517). The same results were obtained from BAL fluids SDC4 levels, which were significantly lower in the advanced stage (IIIb/IV) than in the early stage (I/II/IIIa) (p = 0.007). CONCLUSIONS Serum SDC4 levels in NSCLC patients were lower than those of non-cancer patients. They also performed different results in disease stages. SDC4 could be a helpful biomarker in NSCLC.
Kadar 8-Oxo-7, 8-Dihydro-2’-Deoxyguanosine (8-Oxo-Dgsn) Dalam Urine Sebagai Biomarker Penuaan Pada Pasien Tb Paru Wijaya, Cathrine Meryani; Santoso, Arif; Hamid, Firdaus; As’ad, Suryani; Bukhari, Agussalim; Zainuddin, Alfian
Preventif : Jurnal Kesehatan Masyarakat Vol. 12 No. 2 (2021): Volume 12 No.2 (2021)
Publisher : Tadulako University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22487/preventif.v12i2.448

Abstract

Proses penuaan merupakan proses fisiologis yang tidak dapat dihindari. Pengukuran 8-oxo-dGsn dalam urin berpotensi sebagai cara baru untuk mengevaluasi proses penuaan dalam menentukan dan memperkirakan usia fisiologis. Penelitian ini betujuan untuk mengetahui kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada pasien tuberculosis paru. Penelitian ini menggunakan pendekatan case control yakni penderita TB paru sebagai kelompok kasus dan kelompok orang sehat sebagai control dengan jumlah sampel sebanyak 50 orang (25 orang kasus dan 25 orang kontrol). Data dianalisis dengan menggunakan SPSS 21.0 (SPSS, Inc. Chicago, IL) dengan tingkat kemaknaan α=0.05.Hasil penelitian menunjukkan bahwa Kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada kelompok kasus rata-rata 3.21±0.88. Kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan pada kelompok kontrol rata-rata 2.38±0.71. Ada korelasi positif antara umur dengan kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urin sebagai biomarker penuaan (p < 0,001), dimana semakin bertambah umur maka kadar 8-Hydroxy-deoxyguanosine (8-OHdG) semakin tinggi. Terdapat perbedaan yang bermakna (p:0.001) secara statistik kadar 8-Hydroxy-deoxyguanosine (8-OHdG) sebagai biomarker penuaan antara kelompok kasus dengan kelompok kontrol. Kesimpulan penelitian ini adalah Tuberculosis paru mempercepat proses penuaan yang ditandai dengan peningkatan kadar 8-Hydroxy-deoxyguanosine (8-OHdG) dalam urine sebagai biomarker penuaan.
Co-Authors Abdul Azis, Asrul Adib Khusnul Rois, Adib Khusnul Adnan, Endy Amir Mahmud Ana Rima Setijadi Anas Fadli Wijaya Andarini, Sita Andromeda, Rossalyn Anggit Dwi Hartanto, Anggit Dwi Anggita, Dwi Anwar Muqorobin Arfiansyah, Mochammad Aris Asy'hari, Mohammmad Alif As’ad, Suryani Bukhari, Agussalim Candrakusuma, Muslih Choirul Huda Diyan Martha , Rahma Djaharuddin, Irawaty Elisna Syahruddin Ema Utami Ermayanti, Sabrina Estiko Rijanto Fathoni, M. Faiz Fauzi Ahmad Muda Hamid, Firdaus Haryati Haryati Hendri Maja Saputra Hidayat, Moulid Ida Ayu Putu Sri Widnyani Imanez, Ketzia Adrian Infianto, Andreas Irandi Putra Pratomo IRFAN IDRIS Iskandar, Harun Jasminarti, Ida Ayu Joko Prayitno Susanto Kholifah, Siti Nurriyatul Kinasih, Tutug Kumalasari, Nurul Chamidah Kurniawan, Ferry Dwi Laksmi Wulandari Lihawa, Nurjannah Liong Boy Kurniawan, Liong Boy Lukmanul Khakim Lukni Maulana Martanty Aditya, Martanty MARTHA, RAHMA DIYAN Midriem Mirdanies Milenia Tasya, Syavira Muadhifah, Afidatul Muadifah, Afidatul Muhammad Ilyas Mulyamin, Winda Mustafa, Maulana Saggaf Nawa Suwedi Ngibad, Khoirul Ning Iriyanti Noni Novisari Soeroso Nurdian Susilowati Nurjanah, Mutia Hariani Nurjannah, Mutia Hariani Prasenohadi, Prasenohadi Pratiwi, Widya Wahyu Putra, Andika Chandra Putrawan, Harry Azka Putri, Amalia Eka Rahayu, Selvia Rahmawati, Rahmawati Ratu, Modestus Reba Anindyajati Pratama, Reba Anindyajati RIAN ANGGIA DESTIAWAN Riastus Nayanti Rizqi Andry Ardiansyah Roni Permana Saputra Safitri, Yunita Diyah Santoso, Andintia Aisyah Sari Lestari Sari, Puji Novita Sari, Trianita Setyawan, Ungky Agus Sri Melati Munir Sri Suwarni Sukma Aditya Sulastri Sulastri Syukroni, Azid Teguh Pudji Purwanto Tokumo, Kentaro Tri Rahardjo Sutardi Vikita Windarwati Vita Susanti Widaningsih, Yuyun Wijaya, Cathrine Meryani Wiriansya, Edward Pandu Wulandari, A. Ratna Yustisia, Ika Zaini, Jamal Zainuddin, Alfian