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PENYAKIT FAHR’S DENGAN KEJANG PADA PASIEN KARSINOMA TIROID: SEBUAH LAPORAN KASUS Setiawan, Iwan; Sulistyani, Sulistyani
Biomedika Vol 13, No 1 (2021): Biomedika Februari 2021
Publisher : Universitas Muhamadiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23917/biomedika.v13i1.11796

Abstract

ABSTRAKPenyakit Fahr’s adalah penyakit dengan gangguan neuropsikiatri yang ditandai dengan kalsifikasi di ganglia basalis bilateral dari hasil pemeriksaan pencitraan otak dan biasanya berhubungan dengan gangguan metabolisme fosfor dan kalsium. Artikel ini menyajikan kasus penyakit Fahr’s pada seorang wanita usia 56 tahun dengan karsinoma tiroid dan kejang. Selanjutnya, CT scan kepala menunjukkan adanya kalsifikasi  yang simetris bilateral pada ganglia basalis, dan otak kecil. Manifestasi klinis penyakit Fahr’s bervariasi tergantung usia, letak bagian otak yang mengalami kalsifikasi, dalam hal ini gejala yang dominan adalah jenis kejang berulang berupa bangkitan general tonic clonic. Kejang yang terjadi dalam hal ini bisa jadi akibat perubahan hormon tiroid atau akibat kalsifikasi di otak. Belum ada pengobatan khusus pada penyakit ini,.Gejala kejang yang terjadi mendapatkan terapi dengan sodium valproate dan terapi untuk gangguan perubahan hormon tiroidnya.Kata kunci: Penyakit Fahr’s, Karsinoma Tiroid, Kejang ABSTRAKFahr’s disease is a disease with neuropsychiatric disorder, characterized by bilateral basal ganglia calcification and usually associated with a phosphorus and calcium metabolism disorder. This paper presents a case of Fahr’s disease in a 56-year-old woman with carcinoma thyroid and seizures. Furthermore, CT showed bilateral symmetric basal ganglia and cerebellum calcifications. Clinical manifestations of Fahr’s disease vary depending on age, location of the part of the brain that is calcified, in this case the dominant symptom is recurrent seizures type of the general tonic clonic. Seizures that occur in this case can be resulted of thyroid hormone changes or brain calcification. There is no specific treatment for this disease. The seizures that occur got therapy with sodium valproate and therapy for disorders of thyroid hormone changes.Key words: Fahr’s Disease, Thyroid Carcinoma, WSeizure
Activity Antioxidant on Pigments of Bacterial Symbionts of Soft Coral From Jepara Sea Masduqi, Ahmad Fuad; Franyoto, Yuvianto Dwi; Kusmita, Lia; Muchlisin, Sakti; Widyananto, Prasetyo Abi; Sulistyani, Sulistyani; Wijayanti, Diah Permata
Indonesian Journal of Natural Pigments Vol 2 No 2 (2020): Agustus 2020
Publisher : Ma Chung Research Center for Photosynthetic Pigments

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33479/ijnp.2020.02.02.43

Abstract

Soft corals have been known to produce secondary metabolites, some of which may have anticancer, antifouling, antibacterial and antioxidants activity. It has been suggested that natural products from marine invertebrates have striking similarities to metabolites of their association microorganisms. Symbiont bacteria on soft coral can produce bioactive compounds that play an important role in chemical ecology and as a marine natural product. Marine bacteria associated with soft coral collected from Jepara were successfully isolated on medium ZoBell 2216E and screened to synthesize the pigment. This approach has allowed the use of this organism as an environmentally friendly alternative source of new natural pigment. This study found 25 bacterial isolates from 6 types of soft coral. Out of 25 bacterial isolates, only 3 bacterium, positively contains pigments. Four isolates, PCl 1, PS2 1, and PSa 2. Pigments analysis with UV spectrophotometric method showed the wavelength of pigments were in the range 300-600 nm. Genomic DNA was isolated from these colonies and nested PCR of the DNA was performed to amplify the 16S rDNA. Antioxidant activity was tested with the 1,1-diphenyl-2-picrylhydrazyl (DPPH) method. From the results of molecular identification by 16S rDNA method, it was shown that bacterium PCl 1, PS2 1, and PSa 2 was closely related to Pseudomonas stutzeri, Ponticoccus gilvus, Bacillus marisflavi with 99%, 99and 98% homology value. Antioxidant activity is as follows: PCl 1>PS2 1>PSA 2.
Adsorpsi Multilogam untuk Penurunan Kadar Cu, Fe, Ni dan Zn Menggunakan Arang Aktif Daun Pandan Laut Fillaeli, Annisa; Dwi Siswani, Endang; Kristianingrum, Susila; Sulistyani, Sulistyani; Delapril Pratiwi, Ajeng
Jurnal Sains Dasar Vol 8, No 2 (2019): October 2019
Publisher : Faculty of Mathematics and Natural Science, Universitas Negeri Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21831/jsd.v8i2.38788

Abstract

Penelitian ini bertujuan untuk mengetahui waktu kontak dan konsentrasi yang paling optimum pada adsorpsi arang aktif daun pandan laut teraktivasi NaOH 1% terhadap ion multilogam Cu2+, Fe3+, Ni2+ dan Zn2+ dan mengetahui efisiensi adsorpsi dari adsorben yang paling optimum terhadap ion multilogam Cu2+, Fe3+, Ni2+ dan Zn2+. Subjek dalam penelitian ini adalah arang aktif dari daun pandan laut teraktivasi NaOH 1% dan objek pada penelitian ini adalah efisiensi adsorpsi arang aktif daun pandan laut teraktivasi NaOH 1% terhadap ion multilogam Cu2+, Fe3+, Ni2+ dan Zn2+. Adsorpsi dilakukan dengan mengkondisikan variasi waktu kontak dan konsentrasi ion multilogam. Konsentrasi ion multilogam sebelum dan sesudah adsorpsi diukur dengan Atomic Absorption Spectrophotometer (AAS). Hasil penelitian menunjukkan bahwa waktu kontak optimum untuk adsorpsi ion multilogam Cu2+, Fe3+, Ni2+ dan Zn2+ sebesar 60 menit dan konsentrasi optimum untuk adsorpsi ion multilogam Cu2+, Fe3+, Ni2+ dan Zn2+ berturut-turut sebesar 100, 250, 75 dan 75 ppm dengan efisiensi adsorpsi sebesar 99,606 %, 98,871 %, 56,994 % dan 97,004 %. Kapasitas adsorpsi tertinggi karbon aktif daun pandan laut teraktivasi NaOH 1% terhadap ion-ion logam Cu2+, Fe3+, Ni2+ dan Zn2+ berturut-turut terjadi pada konsentrasi 250, 250, 125 dan 250 ppm dengan kapasitas adsorpsi sebesar 2,9358 mg/g, 3,7877 mg/g, 0,8299 mg/g dan 2,3397 mg/g.
Telemedicine in stroke patients during the COVID-19 pandemic: Literature Review Pradani, Indra; Sulistyani, Sulistyani
International Journal of Health Science and Technology Vol. 5 No. 2 (2023): November
Publisher : Universitas 'Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/ijhst.v5i2.3338

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The effectiveness of stroke therapy depends on speed, accuracy and a multidisciplinary approach. The era of the COVID-19 pandemic has caused a high risk of treatment for stroke patients. The application of telemedicine or telestroke that is good and focuses on quality is a possible alternative for stroke therapy during the COVID-19 pandemic. This study aims to determine the effectiveness of telemedicine in stroke patients during the COVID-19 pandemic. This study used a systematic review research design, namely by searching journal articles on Google Scholar, PubMed, and Research Gate databases, using keywords ("Telemedicine" OR "Tele stroke") AND ("stroke" OR "strokes" OR "cerebrovascular accident" OR "cerebral stroke") AND ("COVID 19" OR "COVID-19 Virus Disease" OR COVID19 OR "Coronavirus disease 2019").  Based on searching and searching for journal articles in 2019 - 2021, 131 journals were obtained from PubMed, 90 journals from ResearchGate, and 1000 journals from Google Scholar.  A total of 1221 journals were obtained, and 8 scientific articles fit the inclusion criteria. It can be concluded that the application of telemedicine in stroke patients during the COVID-19 pandemic has been implemented in various countries with evidence that it can reduce comorbidities, improve clinical outcomes, and reduce the recurrence of stroke patients. Telemedicine can be applied to stroke patients with clear diagnosis criteria, a multidisciplinary approach, and a complete infrastructure.
Determination of Decisions to Use E-Money Applications (QRIS) Priyombodo, Bony; Nurchayati, Nurchayati; Sulistyani, Sulistyani; Widayati, Tri
Research Horizon Vol. 4 No. 1 (2024): Research Horizon - February 2024
Publisher : LifeSciFi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54518/rh.4.1.2024.225

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In the era of digital industrial growth and industrial revolution 4.0, the banking sector is experiencing significant changes. This research aims to analyze the factors that influence the decision to use the e-money application (QRIS) by Bank Rakyat Indonesia KC Semarang Pandanaran customers. The factors considered are e-service quality, user experience, and usefulness. The population in this study were customers of Bank Rakyat Indonesia KC Semarang Pandanaran, with the sample size used in this study being 100 customers taken using a purposive sampling technique, with criteria customers who have used QRIS at least 2 times. The data source used is primary data, with data collection methods using questionnaires. The data analysis technique used in this research is multiple linear regression analysis. The research results show that partially, e-service quality, user experience, and usability have a positive and significant influence on usage decisions. customers. The significance results obtained indicate that the higher the e-service quality, the better the user experience, and the higher the usefulness, the decision to use customers will increase. The implication of these findings is the importance of paying attention to and improving these factors in an effort to improve usage decisions customers in using the e-money application (QRIS).
STUDENT LEARNING EXPERIENCE THROUGH MICROSOFT TEAMS DURING THE PANDEMIC ERA Mardhiyyah, Ana; Sulistyani, Sulistyani; Wicaksono, Agung; Khoiriyah, Khoiriyah
Premise: Journal of English Education and Applied Linguistics Vol 11, No 3 (2022): Premise Journal: e-ISSN 2442-482x, p-ISSN 2089-3345
Publisher : Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/pj.v11i3.5865

Abstract

Students learning experiences are affected by the spread of Covid-19 in cognitive, affective, and behavioral domains. This research investigates the university students' experience using the Microsoft Teams application in online learning during the Covid-19 Pandemic. The experience includes their perception, problems, and how they use Microsoft Teams daily. It is descriptive quantitative research under a case study. The participants were 97 university students consisting of 50 female and 47 male students spread over various universities. The data collection techniques were questionnaires and five open-ended questions. The questionnaires were analyzed using the Likert scale through SPSS (Statistical Package for the Social Sciences), while five open-ended questions were analyzed using the content analysis technique. The results showed that the students had a good experience using Microsoft Teams. They also have much improvement in English skills, especially in speaking skills. However, they needed help using Microsoft Teams, had unstable internet connections, and found it hard to improve their reading skills. Nonetheless, students hope that this application will continue to be used during online learning with some improvements so that learning using this application can take place more effectively and efficiently. This study implies that Microsoft Teams can support English skill development in an online learning environment.  
DEVELOPING STUDENTS’ CREATIVITY IN TEACHING TEYL SUBJECT DURING COVID-19 PANDEMIC Auraningrum, Zakia; Nurhajati, Diani; Sulistyani, Sulistyani
Premise: Journal of English Education and Applied Linguistics Vol 11, No 3 (2022): Premise Journal: e-ISSN 2442-482x, p-ISSN 2089-3345
Publisher : Universitas Muhammadiyah Metro

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24127/pj.v11i3.5866

Abstract

The COVID-19 pandemic has influenced the education world, especially teaching and learning. Students must be equipped with four skills to survive in the global competition of the 21st century, namely Collaboration, Critical Thinking, Creativity, and communication (4C). One of the essential skills is creativity. Teachers have to provide learning activities for students to develop their skills. As a result, teachers must adapt to the condition by selecting the appropriate strategies. One of the strategies which can be applied during the pandemic is Project Based Learning. This study aims to describe the process of developing creativity in the students using Project Based Learning in the Teaching English to Young Learners (TEYL) course and the student's responses towards the strategy applied by the lecturer. This study is qualitative; the data were collected by documentation, observation checklist, and interviews. The subjects are lecturers and students taking TEYL courses for the 2020/2021 academic year. This study found that the lecturer employed blended learning to implement the teaching and learning process. She assigned the students a project: learning activities for young learners in the form of a book chapter. Through creating the project in TEYL courses, the students could develop their creativity, especially in fluency, flexibility, originality, and elaboration.
Peningkatan Kemampuan Interaksi Sosial Anak Melalui Metode Bermain Peran Sulistyani, Sulistyani; Herawati, Herawati; Sudarti, Sudarti
Journal of Early Childhood and Character Education Vol 3, No 2 (2023)
Publisher : FITK UIN Walisongo Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21580/joecce.v3i2.17530

Abstract

Kemampuan interaksi sosial anak di kelompok A RA Fatih Al-Baariq Desa Jawa Tengah memiliki kecenderungan anak bermain sendiri, kurangnya anak dalam bergaul, tidak saling tegur sapa, masih jarang melakukan kontak mata saat bercakap - cakap, dan saat proses masih berpusat pada guru yang menyebabkan pembicaraan lebih banyak didominasi oleh guru. Tujuan penelitian adalah mengetahui kondisi objektif kemampuan interaksi sosial anak sebelum diterapkan metode bermain peran dan penerapan metode bermain peran dalam meningkatkan kemampuan interaksi sosial anak. Metode penelitian menggunakan tindakan kelas yang kolaboratif dengan bermain peran profesi. Subjek dalam penelitian berjumlah 23 anak. Hasil penelitian i adalah kemampuan interaksi sosial anak mengalami peningkatan pada setiap indikator diantaranya anak mampu menyapa, anak mampu berkomunikasi secara verbal, anak mampu meminta bantuan, anak mampu menyimak, anak mampu bertanya dan anak mampu bercakap-cakap. Rekomendasi yang diberikan meningkatkan interaksi sosial anak sebagai metode yang menarik, dan memotivasi dan melibatkan anak secara langsung .
Hubungan Kadar HbA1c dan Usia dengan Kejadian Neuropati Diabetik pada Pasien Diabetes Melitus Fikri, Elfin Ainul; Sulistyani, Sulistyani; Setiawan, Iwan; Puspitasari, Metana
Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal Vol 14 No 3 (2024): Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal: Juli 2024
Publisher : Sekolah Tinggi Ilmu Kesehatan Kendal

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32583/pskm.v14i3.1986

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Neuropati diabetik adalah rusaknya sistem saraf tepi yang disebabkan oleh pembuluh darah mikro yang rusak sehingga darah tidak bisa mengalir ke jaringan saraf. International Diabetes Federation memperkirakan 463ijuta orang dimseluruh dunia menderitaidiabetes melitus per tahun 2019. Kejadian diabetesnmelitus di Indonesia menempati peringkat ketujuh dunia dengan 10,7 juta kasus. Prevalensi neuropatimdiabetik padanpasien diabetesnmelitus mencapai 40,3%. Kejadian neuropati diabetik meningkatnseiring bertambahnyanusia pasienidiabetes melitus. Kejadian neuropati dapat diprediksi melalui kontrol glikemik yang ketat dengan memantau kadar HbA1c. Penelitian ini bertujuan untuk mengetahuinhubungan antara usia dannkadar HbA1c dengan kejadiannneuropati diabetiknpada pasien diabetes melitus. Penelitian ini menggunakan desain penelitian analitik observasional dengan pendekatan cross-sectional. Sampelnpada penelitiannini merupakan semua penderita diabetes melitus yang memiliki kriteria sesusai dengan yang diperlukan peneliti dengan jumlah sebanyak 65 sampel yang dipilih dengan menggunakan pendekatan total sampling. Neuropati diabetikndiukur dengan menggunakan tes monofilamen. Berdasarkan uji Chi-Square, hasil antara kadar Hb1Ac dengan neuropati diabetik pasien diabetes melitus didapatkan p-value =0,000. Sedangkan uji Chi-Square antara usia dengan neuropati diabetik pasien diabetes melitus didapatkan p-value =0,000. Terdapat hubungan yang signifikannantara HbA1c dan usia dengannkejadian neuropati diabetik pada pasien diabetesnmelitus di Puskesmas Gatak, Kabupaten Sukoharjo.
PENYULUHAN TENTANG KUALITAS TIDUR PADA MASA PANDEMI COVID-19 Sulistyani, Sulistyani
Jurnal Pengabdian Masyarakat Medika Vol 1. No. 2, September 2021
Publisher : Universitas Muhamamdiyah Surakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (239.784 KB) | DOI: 10.23917/jpmmedika.v1i2.367

Abstract

ABSTRAK Pandemi COVID-19 menimbulkan berbagai masalah kesehatan masyarakat di seluruh dunia, salah satunya adalah trauma psikis yang dapat mempengaruhi kualitas tidur. Kualitas tidur sulit untuk didefinisikan namun dapat diidentifikasi dengan istrumen penilaian PSQI Pittsburgh Sleep Quality Index). Kualitas tidur yang baik mempunyai peran penting dalam meningkatkan fungsi kognitif terutama retensi memori. Kualitas tidur malam yang buruk menyebabkan kantuk di siang hari dapat mempengaruhi kesehatan fisik dan kognitif pada pelajar atau mahasiswa siswa dan mempengaruhi nilai akademik. Tujuan penyuluhan ini adalah untuk meingkatkan pengetahuan tentang kualitas tidur yang baik. Hasil penyuluhan terdapat 60% gangguan tidur pada peserta penyuluhan dan terdapat peningkatan pengetahuan tentang kualitas tidur. Simpulan yang dapat diambil adalah penyuluhan dapat meningkatkan pengetahuan tentang kualitas tidur yang baik.   ABSTRACT The COVID-19 pandemic causes psychological trauma. It has an impact on sleep quality. PSQI (Pittsburgh Sleep Quality Index assessment instrument) is the instrument to identify sleep quality disorders. Good quality sleep can improve cognitive function, particularly memory retention. A poor night's sleep quality causes daytime sleepiness and affects physical, cognitive health, and academic grades. The purpose of the counseling is to increase knowledge about good sleep quality. There were 60% sleep disorders in counseling participants and an increase in knowledge about sleep quality. The conclusion is counseling can increase knowledge about good sleep quality.
Co-Authors Abd. Rasyid Syamsuri Adedhea, Marchita Agung Wicaksono Ahmad Fuad Masduqi Ahyansyah, Ahyansyah Aji, Mahendra Puji Permana Amalia, Riza Amandia Dewi Permana Shita Annisa Fillaeli Apay, Frengky Apriyanto, Arif Ariyanti, Rika Auraningrum, Zakia Azzah, Millenia Syafirah Yunita Bakhtiar Fahmi Fuadi Budianto, Pepi Damayanti, Elok Delapril Pratiwi, Ajeng Devi Usdiana Rosyidah Dewi, Endang Kusuma Diah Kurnia Mirawati Diah Permata Wijayanti Diani Nurhajati Diki Retno Yuliani, Diki Retno Dwi Siswani, Endang Faghfirlie, Faghfirlie Fauziah, Nida Faradisa Felle, Zeth Roberth Fikri, Elfin Ainul Fortuna, Tista Ayu Franyoto, Yuvianto Dwi Gentidatu, Sofietje Gunawan, Kadek Putra Dharma Hambarsari, Yetty Hamidah, Tasya Hamidi, Baarid Lukman Hapsari, Wanodya Hartini Sulistyandari, Hartini Herawati Herawati Ismanto, Deny Iwan Setiawan Khoiriyah Khoiriyah Korinus Suweni Krestianto, Indah Dwi Widyasari, Deny Puji Lestari, Nining Lia Kusmita Maharani, Suciana Manangsang, Frans Mandowen, Rospuana Mardhiyyah, Ana Marjuanah, Marjuanah Mawaddah, Sukma Mebri, Elisabeth Milyarona, Fitri Pranita Muchlisin, Sakti Mukadar, Lilis Afriyani Mulyani, Amelia Sri Mursid Raharjo Muspitha, Fitri Diah Mustofa , Dwi Hanif Nikita, Aulia Bea Nur Mahmudah Nurchayati Nurchayati Nurjazuli Nurjazuli Pongtiku, Sri Rejeki L. Prabaningtyas, Hanindya Riani Prabowo, Alifia Istiqomah Pradani, Indra Pradanti, Paskalia Prastyo Abi Widyananto Prayogi, Muhammad Dharma Prehanawan, Refian Putra Priyombodo, Bony Purba, Elen Purwandani Winarso, Septerina Purwita Sari, Purwita Puspitasari, Metana putra pradnyana, I made bramastya Ratnasari, Yuhanida Rayidah, Tasya Renatasari, Distya Ayu Retno Sintowati - Rini, Hanggana Sekar Rino Sardanto Riskiana, Shafira Yuni Rivan Danuaji Rophi, Kristiyani Herda Rumaseb, Ester Safitri, Aisyah Nur Saputri, Gafrila Fani Eka Sari, Nur Amalia Sarif, Nabil Nawal Setyo Nurwaini Sinta, Mutia Siti Soekiswati Sri Ngayomi Yudha Wastuti, Sri Ngayomi Subardjo Subardjo, Subardjo Sudarti Sudarti Supri Ahmadi, Supri Suriyani Suriyani, Suriyani Suroto Suroto Susila Kristianingrum Sutirtha, I Wayan Swastika, I Ketut Syahidah, Shofia Rif'atusy Tri Agustina, Tri Tri Widayati Utami , Anita Dwi Utari, Berlian Wahyuningtias, Merisa Wibowo, Mahadevi Cinantyan Yesi Franita Yusuf Alam Romadhon