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Analgesia For Dressing Changes In Burns: A Systematic Review Ramadan, Mohamad Rachadian; Wardhana, Aditya; Sugiarto, Adhrie
Jurnal Plastik Rekonstruksi Vol. 5 No. 1 (2018): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (352.367 KB) | DOI: 10.14228/jpr.v5i1.249

Abstract

Background: Intense and prolonged pain often caused by burn injuries. The greatest pain is mostly experienced during dressing changes to maintain healing and banish the infection. This review is conducted to assess the effectiveness and safety of different analgesia agents or methods for dressing changes in burn patients. Method: Searches of studies conducted from 4 electronic databases, using keywords “Analgesia”, “Dressing”, “Bandages”, “Changes” and “Burns”. We included randomized and quasi-randomized trials assessing and comparing the effects of different analgesia agents, analgesia methods for dressing changes in burns patients. We excluded trials reporting only pharmacokinetic and physiological outcomes, comparing drug dosages, with exception for those using different drugs in the same class. Result: Multiple databases search retrieved 144 studies. 17 trials are eligible involving 700 patients. Analgesia using pharmacological agents in 7 trials; 5 trials elaborating primary treatments and 2 trials as the adjunct treatment complementing the major analgesia. Two primary analgesia treatments were studying the role of patient-controlled analgesia (PCA), while 3 trials using caregiver delivered. Ten trials were observing the role of non-pharmacological analgesia. Conclusion: There was inadequate evidence from comparisons tested in randomized trials to confirm the dependent effectiveness of various techniques of analgesia, individual methods, or to assess the administration of different drug adjuncts for providing analgesia during dressing changes. Given the unresolved questions about the management of these conditions, we suggest that preference should be focused on the large scale, optionally, multi-center randomized observations of the primary methods.
Demographic Characteristic Of Burn Mortality And Its Relation To Tangential Excision At Burn Unit Of Cipto Mangunkusumo National General Hospital Wardhana, Aditya; Kurniasari, Dhita
Jurnal Plastik Rekonstruksi Vol. 5 No. 1 (2018): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (351.467 KB) | DOI: 10.14228/jpr.v5i1.253

Abstract

Background: Burn injury is considered as major problem because of high mortality and morbidity. One of the several managements to decrease the mortality rate is wound excision. This study aimed to describe the characteristics of burn mortality in our burn unit and its association with timing of tangential excision. Method: We collect data of burn patients who died in 2016 at Burn Unit of Cipto Mangunkusumo Hospital. We investigate the association of mortality and timing of tangential excision. The data were compared with other studies from online databases. Result: Thirty-four burn patients died at RSCM Burn Unit from January - December 2016. 13 patients underwent early tangential excision, the rest had delayed or no tangential excision. Only length of stay (LOS) has statistically significant result. The early tangential excision group has significantly longer median LOS (p=0.003) compared to delayed tangential excision. From five relevant studies, three studies had higher mortality in early tangential excision group compared to delay group but fewer complications and shorter LOS. Two studies reported a significant reduction in mortality in early tangential excision group while culture positive wounds were more frequent in the delay group. Conclusion: Mortality in our patients in early tangential excision group is fewer than the delayed one. The early tangential excision group has longer length of stay compared to delay tangential excision. Although there are pros and cons from the literature review, we suggest that early tangential excision should be done in burn patients.
Association Between Serum Albumin And The Success Of Fluid Resuscitation In Children Hospitalizen In Cipto Mangunkusumo Hospital Burn Center Dewi, Rismala; Kaltha, Karina; Wardhana, Aditya; Yanuarso, Piprim B.
Jurnal Plastik Rekonstruksi Vol. 5 No. 2 (2018): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (240.84 KB) | DOI: 10.14228/jpr.v5i2.259

Abstract

Background : Burn injury has a great impact on mortality and morbidity in children. Significant loss of albumin (hypoalbuminemia) in burn patient often leads to serious complications. However, it is still unclear whether serum albumin has a role in the success of fluid resuscitation in children with burn injury. Method : This is a retrospective cohort study based on medical record of children hospitalized with burn injury at Cipto Mangunkusumo Hospital Burn Centre from January 2012-March 2018. The subjects collected with the total sampling method. Result : Most burn injury happen because of scalds, and have grade 2 burn injury with PELOD score<10. Almost all subjects was succesfully resuscitated in the first 24 hour (95,1%). No association was found between the success of fluid resuscitation with either serum albumin [RR 1,175(95%CI 0,3-4,4) p=0,812], or with ureum, creatinin, lactate level, weight and the degree/extent of the burn injury. Conclusion: The success rate of fluid resuscitation in pediatric burn injury was quite high in Cipto Mangunkusumo Hospital Burn Centre. No association was found between serum albumin and the success of fluid resuscitation during the first 24 hour period. Keywords: albumin, burn, pediatric, resuscitation
Epidemiology And Mortality Of Burn Injury In Ciptomangunkusumo Hospital, Jakarta: A 5 Year Retrospective Study Wardhana, Aditya; Winarno, Gammaditya Adhibarata
Jurnal Plastik Rekonstruksi Vol. 6 No. 1 (2019): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jpr.v6i2.269

Abstract

Background : Burns is a significant cause of morbidity and mortality worldwide. Particularly in low- and middle-income countries (LMICs), burns account for an estimated 180.000 deaths every year. Burn-related mortality rates are exceptionally high in South-East Asia (11.6 deaths per 100 000 population per year) compare with much lower rates of 1.0 deaths per 100.000 people per year in high-income countries. This study aims to investigate the demographic data, etiology, and outcome of the patients treated in burn unit Ciptomangunkusumo Hospital, Jakarta, Indonesia. Method: This is a retrospective cross-sectional study, collecting epidemiologic data from the medical record through Electronic Health Record. A total of 709 patients admitted to burn unit between 2013-2017 were reviewed based on age, sex, total burn surface area (TBSA), burn grade, inhalation injury, etiology, length of stay, outcome, and payment method. Inclusion criteria are patients that were admitted to burn unit of Ciptomangunkusumo Hospital between 2013-2017, while there are no exclusion criteria in this study. Result : Admission of patients between 2013-2017 has inclined throughout the year, from 97 in 2013 to 166 in 2017. Average patient admission per year, reaching 141,8±26,761. Jakarta, and its suburb Bogor, Depok, Tangerang, and Bekasi, has dominated the proportion of referring hospital with 538(75.9%) The most amount of payment method is NHI (JKN/BPJS) with 534(75.3%) population. A total of 465 were male, and 244 were female, with a ratio of 1.9:1. The highest incidence in terms of age group is 16-35 years old (269, with the average age of patients, is 29±19. The highest incidence of burn injury is caused by a stove gas explosion with 253(35.7%), followed by flame 189(26.7%). There are 63 out of 709 patients with inhalation injury, where the incidence rate is 8.9%. Patients admitted to the Ciptomangunkusumo burn unit has an average length of stay of 15 days hospitalization. The most frequent population of extent, staying >14 days is 21-30% TBSA (88). The mortality rate in the Ciptomangunkusumo burn unit is 25.8% (183), with the highest number of death came from TBSA >40% (136). Conclusion: A total of 709 patients were admitted to the Ciptomangunkusumo burn unit in Jakarta, Indonesia, over 5 years, with an average of 141 patients per year and an increase of 171% from 2013 to 2017. Most patients were diagnosed with >40% TBSA and 2nd-3rd grade burn injury. An average of 15 days of hospitalization for patients leading up to 25.8% mortality rate, they are with septic shock as the most common condition causing death in the burn unit.
Epidemiology And Mortality Of Burn Injury In Ciptomangunkusumo Hospital, Jakarta: A 5 Year Retrospective Study Wardhana, Aditya; Winarno, Gammaditya Adhibarata
Jurnal Plastik Rekonstruksi Vol. 6 No. 1 (2019): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1162.132 KB) | DOI: 10.14228/jpr.v6i1.270

Abstract

Background : Burns is a significant cause of morbidity and mortality worldwide. Particularly in low- and middle-income countries (LMICs), burns account for an estimated 180.000 deaths every year. Burn-related mortality rates are exceptionally high in South-East Asia (11.6 deaths per 100 000 population per year) compare with much lower rates of 1.0 deaths per 100.000 people per year in high-income countries. This study aims to investigate the demographic data, etiology, and outcome of the patients treated in burn unit Ciptomangunkusumo Hospital, Jakarta, Indonesia. Method: This is a retrospective cross-sectional study, collecting epidemiologic data from the medical record through Electronic Health Record. A total of 709 patients admitted to burn unit between 2013-2017 were reviewed based on age, sex, total burn surface area (TBSA), burn grade, inhalation injury, etiology, length of stay, outcome, and payment method. Inclusion criteria are patients that were admitted to burn unit of Ciptomangunkusumo Hospital between 2013-2017, while there are no exclusion criteria in this study. Result : Admission of patients between 2013-2017 has inclined throughout the year, from 97 in 2013 to 166 in 2017. Average patient admission per year, reaching 141,8±26,761. Jakarta, and its suburb Bogor, Depok, Tangerang, and Bekasi, has dominated the proportion of referring hospital with 538(75.9%) The most amount of payment method is NHI (JKN/BPJS) with 534(75.3%) population. A total of 465 were male, and 244 were female, with a ratio of 1.9:1. The highest incidence in terms of age group is 16-35 years old (269, with the average age of patients, is 29±19. The highest incidence of burn injury is caused by a stove gas explosion with 253(35.7%), followed by flame 189(26.7%). There are 63 out of 709 patients with inhalation injury, where the incidence rate is 8.9%. Patients admitted to the Ciptomangunkusumo burn unit has an average length of stay of 15 days hospitalization. The most frequent population of extent, staying >14 days is 21-30% TBSA (88). The mortality rate in the Ciptomangunkusumo burn unit is 25.8% (183), with the highest number of death came from TBSA >40% (136). Conclusion: A total of 709 patients were admitted to the Ciptomangunkusumo burn unit in Jakarta, Indonesia, over 5 years, with an average of 141 patients per year and an increase of 171% from 2013 to 2017. Most patients were diagnosed with >40% TBSA and 2nd-3rd grade burn injury. An average of 15 days of hospitalization for patients leading up to 25.8% mortality rate, they are with septic shock as the most common condition causing death in the burn unit.
Tissue Engineering and Regenerative Medicine: A Review Wardhana, Aditya; Valeria, Michelle
Jurnal Plastik Rekonstruksi Vol. 7 No. 1 (2020): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (1264.186 KB) | DOI: 10.14228/jpr.v7i1.278

Abstract

Summary: The concept of tissue engineering has now been accounted for one of the most prospective answers to the growing needs of tissue and organ replacements. Many studies and researches are continuously done to achieve a paramount strategy in tissue engineering and regenerative medicine. This review emphasizes the concept, strategies, current application, and current challenges in tissue engineering. The strategy in tissue engineering has much improved and successfully applied in several reconstructive cases. Understanding of isolated cells’ behaviors, materials suitable for its’ scaffolds, in adjuncts with specific growth-inducing factors for each specific tissue or organ built is the key for successful tissue engineering. Ringkasan: Konsep tissue engineering merupakan salah satu jawaban yang paling diharapkan dapat memenuhi kebutuhan pengganti jaringan dan organ yang terus meningkat pada saat ini. Beragam studi dan penelitian secara terus-menerus dilakukan agar dapat memperoleh strategi terbaik dalam tissue engineering dan regenerative medicine. Artikel ini berfokus pada konsep, strategi, aplikasi terkini, dan tantangan di masa mendatang pada tissue engineering. Strategi tissue engineering telah banyak berkembangan dan berhasil diterapkan pada kasus-kasus rekonstruksi. Pemahaman mengenai perilaku sel, kecocokan material dengan scaffolds, serta faktor pendukung pertumbuhan untuk masing-masing jaringan atau organ spesifik yang akan diciptakan merupakan kunci keberhasian tissue engineering.
Antioxidants Reduce Tissue Necrosis in The Zone of Stasis: Review of Burn Wound Conversion Wardhana, Aditya; Halim, Jessica
Jurnal Plastik Rekonstruksi Vol. 7 No. 1 (2020): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (512.337 KB) | DOI: 10.14228/jpr.v7i1.292

Abstract

Summary: Severe burns are devastating condition identified by loss of hemodynamic stability and intravascular volume. Adequate fluid replacement, nutritional support, and immediate wound grafting can reduce the risk of infection and mortality. Oxidative stress was shown to have significant role in the burn wound conversion, which happens when the zone of stasis can’t be salvaged and progresses to necrosis. Decreasing the level of oxidative stress early may be fundamental in reducing burn injury progression into deeper tissue. Several animal studies have demonstrated the advance of antioxidant supplementation for burns outcomes. Approach to this salvageable burn tissue is a breakthrough for new directions in burn management. Antioxidant supplementations was proven to prevent burn conversion on the ischemic zone. Administering antioxidant post-burn is linked with less progression of burn depth and inflammatory cytokine release, which alleviates burn-related morbidity and mortality and improves patient’s quality of life. To date, no clinical trials have been done to reproduce similar outcomes of this ROS-scavenging therapy as successfully observed in murine models. Antioxidant supplementation is a promising treatment avenue to halt burn wound conversion following severe burns. Keywords: Burn wound, wound conversion, burn management, antioxidant
The Effect of Early Tangential Excision and Split Thickness Skin Graft in Reducing Length of Stay in Burns Patients in Jakarta Islamic Hospital Cempaka Putih Wardhana, Aditya; Winarno, Gammaditya Adhibarata; Tanjunga, Sanjaya Faisal; Augiani, A. S; Zidna, An’umillah Arini
Jurnal Plastik Rekonstruksi Vol. 8 No. 1 (2021): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v8i1.309

Abstract

Introduction: Early tangential excision (TE) and split-thickness skin graft (STSG) have increased the outcome in burn patients treated at specialized burn centers. This study was conducted to compare the length of stay (LOS) in burn patients undergoing early TE & STSG and delayed TE & STSG. Method: This is a retrospective cross-sectional study including 42 patients with varied burn degrees, and TBSA admitted to Jakarta Islamic Hospital Cempaka Putih (JIHCP) Burn Unit. Patients were assigned to two study groups, the early TE & STSG group including 32 patients and the delayed TE & STSG group including 10 patients. All data were collected from the medical record and compared between two study groups. Result: The mean of LOS in a group with early TE & STSG was shorter (9.81±6.41 days) than LOS in the delayed TE & STSG group (15.80±5.67 days). The data of LOS between these groups were compared using an independent T-test. The LOS in the early TE & STSG group was significantly shorter than the delayed TE & STSG group (p=0.012). Conclusion: In patients with burn injuries, early TE & STSG is associated with a shorter length of stay than the delayed TE & STSG. Our study indicates that early excision within five days after burn injury is optimal to reduce the length of stay in burn patients.
The Difference in TBSA Estimation Between Emergency Room and Burn Unit in Second Tier Hospital in Central Jakarta Wardhana, Aditya; Winarno, Gammaditya A.; Tanjunga, Sanjaya F.; Zidna, An’umillah Arini; Augiani, Amani S.
Jurnal Plastik Rekonstruksi Vol. 8 No. 1 (2021): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v8i1.310

Abstract

Introduction: Burn TBSA estimation is essential to administer fluid resuscitation. There are some methods, including Rule of 9 and Lund-Browder Chart. This study aims to identify the difference in TBSA estimation in Emergency Room & Burn Unit. Method: We conducted a retrospective cross-sectional study in design. The Inclusion criteria are patients admitted to the Jakarta Islamic Hospital Cempaka Putih (JIHCP) burn unit between April 2015-September 2018, acute patients who have complete demographic data, complete TBSA estimation in the emergency room (ER) and burn unit (BU). Exclusion criteria are patients who do not have complete demographical data and incomplete TBSA estimation between the emergency room and burn unit. The estimation of TBSA in the emergency room is done by General Practitioner, while in the burn unit is done by Plastic Surgeon. Result: Of all 160 patients admitted, 142 patients are eligible in the inclusion criteria.  Most of it was adult males with an average of 28.3 years old, suffering a grade II burn injury caused by scald. There is a higher mean of TBSA estimation in the Emergency room with 15.83 (SD 12.21) compared to the Burn Unit with 12.92 (SD 12.00). The maximum TBSA overestimation in ER reaches 24% TBSA than BU, while the minimum is 0.5%. The Maximum TBSA underestimation in ER reaches 20% TBSA than BU, while the minimum underestimation is also 0.5%. On average, ER overestimates about 6.7% TBSA and underestimates about 2.8% TBSA compared to BU. Conclusion: The emergency room tends to overestimate the TBSA, with an almost 3% difference in mean (p<0.05). There is an occurrence of a maximum 24% TBSA overestimation while averaging 6.7% TBSA.
Nutrition Therapy in Type 2 Diabetic Burn Patient Ramadhania, Dian Araminta; Wardhana, Aditya; Sinaga, Wina; Wulandari, Yohannessa; Daya, Mulianah; Octovia, Lily Indriani
Jurnal Plastik Rekonstruksi Vol. 8 No. 1 (2021): Jurnal Plastik Rekonstruksi
Publisher : Lingkar Studi Bedah Plastik Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14228/jprjournal.v8i1.314

Abstract

Summary: Severe burn patients experience pronounced metabolic changes that caused hyperglycemia. Other existing metabolic conditions such as diabetes mellitus may worsen this condition. Early, adequate, and personalized nutrition therapy may result in better glycemic control and prognosis.A 44-year-old male with severe burn injury involving 27,5% total body surface area (TBSA) and type 2 diabetes mellitus (T2DM) was given early and diabetes-specific nutrition therapy to meet the recommended energy and protein needs. Lower carbohydrate contents and higher mono-unsaturated fatty acids (MUFA) were components of diabetes-specific nutrition therapy. Desirable blood glucose levels, a positive trend of albumin levels, and reduced inflammatory markers were achieved while being given this nutrition therapy. Sepsis was not diagnosed in this patient. The patient was discharged from the hospital after an improvement in clinical condition. Hyperglycemia commonly occurs in critically ill patients, especially with pre-existing T2DM. The provision of prompt and personalized nutrition therapy will improve clinical outcomes.
Co-Authors Affandy Agusman Aris Agne Nabilah Agnelia, Revina Anisa Agusman Aris, Affandy Al Hazmi, Nadhil Alief Maulana Aldi Akbar Amalina Fitria, Nur Anisa Agnelia, Revina Arief, Ilham Arif Kuswanto Augiani, A. S Augiani, Amani S. Azhari, Nadya Dewi Bando, Nurjannah Budi Harto Budi Rustandi Kartawinata Cakranegara, Pandu Adi Christabella, Rininta Citra, Khansa Fairuz Cleopas Martin Rumende Dadang Sudrajat Daya, Mulianah desi kristanti, desi Dg. Mapata Dien, Siphora Dwikawardhana, Galih Santika Dyah Maharani E. Mudjaddid A. Siswanto Deddy N.W.Achadiono Hamzah Shatri Efendi Efendi Em Yunir, Em Erni Juwita Nelwan, Erni Juwita Faizah, Ana Farhana, Nadya Feroniasanti, Lauda Hafifah, Ariqah Nur Halim, Jessica Hartini Hartini Hartini Hartini, Hartini - Hendy Tannady Hernawan, Moch Arif Insani, Al Fajrin Irmia Kusumadewi Irzan Soepriyadi Joko Ariawan Kaltha, Karina Kameswari, Varra Awaliah Pinus Karimah, Benati Kautsar, Raisya Ayu Kispa, Tera Kristanty Marina Natalia N Kumalawati, July Kurniasari, Dhita Leonard Nainggolan Liem, Isabella Kurnia Lis Lesmini Listiya, Marcella Tirta Mahendra Fakhri Mahir Pradana Marcellus Simadibrata Maya Kasmita Melati Putri , Nandita Melvani, Belvana Putri Meutia Zakaria Miranda, Eliza Mohamad Rachadian Ramadan Mujadid, Fajar N, NORMIYATI Natasha, Bella Nisrina Kamila Normiyati Normiyati Novialdi . Noviandi Syarif , Akhmad Nuryana, Arief Octovia, Lily Indriani Oklia, Sheila Pelitahati, Puguh Piprim B. Yanuarso, Piprim B. Pratama, Aulya Rahman Putri Pratiwi, Intan Pudjiti, Dyah Juliana Pusponegoro, Erdina Hardiono D Putri, Nandita Melati Rachmawaty Rachmawaty Rachmawaty Raharjanti, Natalia Widiasih Rahmah Kusuma, Tyas Rahmawati Rahmawati Rahmawati, Nosita Ramadhania, Dian Araminta Rasyid, Nurhayati M Revi Sesario Revina Anisa Agnelia Ricky Aditya Rismala Dewi Rustam, Musfardi Salma Nurhaliza Sandhi, Afriyanti Sandora, Normalina Santosa, Arby Mauliddan Sapinah Sapinah Sari, Ade Risna Sari, Ayu Diandra Satyani, Metta Sesario, Revi Setiawan, Evania Setyowati, Tri Mulyani Soegeng Wahyoedi Sugiarto, Adhrie Sulaiman, Syarifuddin Suryaningsih, Lilik suryawan, ryan firdiansyah Suyuti, Rizal Syah Putra, Syah Syahputra Syahputra Syahputra, Syahputra Syarif, Akhmad Noviandi Syarifuddin Syarifuddin Tanjunga, Sanjaya F. Tanjunga, Sanjaya Faisal Tedjaatmadja, Chintya Tienni Mariana Simanjorang Tjhin Wiguna Valeria, Michelle Veronica, Raja Merlinda Wina Sinaga Winanda, Rizki Aniza Winarno, Gammaditya A. Winarno, Gammaditya Adhibarata Wulandari, Yohannessa Yahya, Muh. Zainuddin Iba Zeffan Daffa Fitra Haidar Zidna, An’umillah Arini