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PERBEDAAN PENGARUH PEMBERIAN MINYAK KELAPA SAWIT (Palm Oil) DAN MINYAK KELAPA MURNI (Virgin Coconut Oil) TERHADAP PERBAIKAN PROFIL LEMAK (KOLESTEROL) PADA TIKUS DENGAN DIET ATEROGENIK Kusumastuty, Inggita; Andarini, Sri; Anom Aswin, Anak Agung Gede
Jurnal Kedokteran Brawijaya Vol 22, No 3 (2006)
Publisher : Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (193.125 KB) | DOI: 10.21776/ub.jkb.2006.022.03.5

Abstract

Virgin Coconut Oil (VCO) is a kind of coconut oil that most of its contained is Medium Chain Fatty Acids (MCFA) and previous stdy showed that MCFA has an ability to prevent vascular desease. This experiment was done to  prove the ability of virgin coconut oil to reduce cholesteroltotal of rats with atherogenic diet compared with palm oil. This experiment was designed as true pre test post test experiment with control groups. The number of samples were 24 male wistar rats and they were separated into 4 treatment groups in  which each of them has 2 diet sections. The First section was done within 8 weeks, group A got normal diet, group B, Cand D got atherogenic diet with lard, after this section finished all of the groups got cholesterol pre test level. The next 4 weeks, in the second section treatment diet, group A got normal diet, group B got atherogenic diet with lard, group C gotatherogenic diet with palm oil and group D got atherogenic diet with virgin coconut oil, after the second section was over rat cholesterol levels were measured by enzymatic photometric test base on “CHO-PAP”. The results from One Way Anova which was continued to Tukey test showed that group B,C and D were homogenous, but they were different significantly againts group A on pre test with p(0.001) < 0.05.
EFEKTIFITAS ASUHAN GIZI TERHADAP KEPATUHAN ASUPAN NATRIUM DAN PROTEIN PADA PASIEN HIPERTENSI DENGAN GAGAL GINJAL KRONIK DI RSUD Dr. SAIFUL ANWAR MALANG Ningtyas, Ismi; Sudardjo, Meilany Purnamasari; Nafisah, Nabilahasna; Sukarlin, Sukarlin; Kusumastuty, Inggita
Majalah Kesehatan FKUB Vol 6, No 3 (2019): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (572.772 KB) | DOI: 10.21776/ub.majalahkesehatan.2019.006.03.5

Abstract

Asuhan gizi adalah kegiatan yang dilakukan oleh ahli gizi berupa pemberian diet dan edukasi/ konseling gizi serta kolaborasi dengan tenaga kesehatan lain yang dapat membantu dalam menunjang proses penyembuhan pasien. Asuhan gizi pada pasien hipertensi dengan gagal ginjal kronik di RSUD Dr. Saiful Anwar ini bertujuan untuk mengetahui apakah asuhan gizi yang diberikan efektif terhadap kepatuhan asupan natrium dan protein pada pasien hipertensi dengan gagal ginjal kronik. Desain penelitian ini adalah rancangan penelitian korelasional dengan jenis pendekatan cross-sectional pada 30 orang responden yang dipilih secara  purposive sampling. Data penelitian diperoleh melalui rekam medis pasien dan food record selama 3 hari. Analisis data dilakukan menggunakan uji Pearson (asupan protein) dan uji Spearman (asupan natrium). Hasil penelitian menunjukkan bahwa terdapat hubungan yang signifikan antara asuhan gizi yang diberikan dengan asupan protein pasien (p = 0,002). Tidak terdapat hubungan yang signifikan antara asuhan gizi yang diberikan dengan asupan natrium pasien (p = 0,943). Sebanyak 56,7% pasien memiliki output urin >60% asupan cairannya dan 40% memiliki output urin <60% asupan cairannya. Dapat disimpulkan bahwa asuhan gizi yang diberikan mempengaruhi asupan protein pasien, namun tidak pada asupan natrium. Keseimbangan cairan pasien dilihat dari output urin didapatkan sebagian besar lebih banyak dan atau lebih sedikit dari asupan cairannya. 
Anthropometry, Fatty Liver, Plasma Lipid, and Adipose Tissue on Rat Wistar Induced Low-Protein Diet Handayani, Dian; Kusumastuty, Inggita; Tritisari, Kanthi Permaningtyas; Ekawati, Laily; Galuh, Glaveria; Muniro, Lailatul; Satya, Lega; Supratiwi, Ratih Indah; Mahmudah, Anis
Journal of Tropical Life Science Vol 7, No 1 (2017)
Publisher : Journal of Tropical Life Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11594/jtls.07.01.08

Abstract

Protein energy malnutrition problem still exists in developing country. In fact, Indonesia has faced it as double burden of nutrition problems. This study aims to develop a standardized diet for developing protein energy malnutrition (PEM) on the rat to support nutrition research. Low-protein modified AIM-93M diet (LP) has been given to rats for 12 weeks intervention compared to normal protein diet (ND). Anthropometry, plasma lipid, fatty liver and the weight of adipose tissue have been analysed. The LP group showed a significantly lower body weight, body length and waist circumference (p < 0.05), a more fatty liver marker shown in LP compared to ND (p < 0.05). This study suggests that giving low protein modified AIN-M93 diet promotes protein energy malnutrition in the rat.
PENGARUH PEMBERIAN TEPUNG BUAH KESEMEK (Diospyros kaki var. Junggo) SECARA ORAL TERHADAP PEMBENTUKAN FOAM CELLS DI LAPISAN INTIMA AORTA TIKUS PUTIH (Rattus novergicus strain wistar) YANG DIBERI DIET ATEROGENIK Arfiani, Eva Putri; Julia, Arliek Rio; Kusumastuty, Inggita
Jurnal Nutrire Diaita (Ilmu Gizi) Vol 9, No 01 (2017): NUTRIRE DIAITA
Publisher : Lembaga Penerbitan Unversitas Esa Unggul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47007/nut.v9i01.1721

Abstract

Coronary Heart Disease (CVD) is the manifestation of atherosclerosis which is formed of foam cells formation. Beside of medicine, the alternative way to prevent CVD is by high soluble fiber food consumption such as persimmon fruit (Diospyros kaki var. Junggo). The aim of this experiment was to understand the effect of persimmon fruit toward the foam cells formation in the intima aorta layer of rat (Rattus novergicus strain wistar) with atherogenic diet. The experiment was conducted by using experimental laboratoric in vivo with True Experimental Design (Post Test-Only Control Group Design) about 12 weeks, using 5 male rats/group + 1 male rat for spare in each group, the age about 56120 days, and the weight about 100-200 g. The experimental rats were divided into 5 groups, i.e P0 (30.6 g normal diet), P1 (22.9 g atherogenic diet), P2 (22.4 g atherogenic diet + 1.2 g persimmon flour), P3 (21,9 g atherogenic diet + 2.4 g persimmon flour), and P4 (21.4 g atherogenic diet + 3,6 g persimmon flour). Calculation of foam cells was carried out using light microscop with 400x magnification in the area of intima aorta layer of rat. The experiment proved that persimmon flour intervention orally could reduce foam cells formation in the intima aorta layer of white rat with atherogenic diet.  Keywords: atherogenic diet, persimmon, soluble fiber, foam cells
The Effect of Nutritional Education with Leaflet and Diet Application on Nutritional Status Changes in Obese College Students Puspa, Diah; Handayani, Dian; Kusumastuty, Inggita
Unnes Journal of Public Health Vol 10 No 2 (2021): Unnes Journal of Public Health
Publisher : Universitas Negeri Semarang (UNNES) in cooperation with Association of Indonesian Public Health Experts (Ikatan Ahli Kesehatan Masyarakat Indonesia (IAKMI))

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15294/ujph.v10i2.43150

Abstract

Obesity is excessive body fat condition due to differences in energy consumption and expenditure. In Indonesia, the prevalence of obese women >18 years old is 32.9%. Interventions are performed with control eating and increased physical activity through an educational approach. A Leaflet is a print media containing some information, while my weight loss diet application is used by people that want to lose weight. Therefore, this study aims to determine the effect of nutritional education with leaflet and my weight loss diet application on nutritional status changes in obesity. True experimental design was used with pre-post test on female students divided into two groups in Universitas Brawijaya (n= 44) and selected by purposive sampling. Also, Independent-Samples T-Test and Mann Whitney analysis were conducted. The results showed a body mass index decrease in both media and no significant change related to BMI (p = 0.733). However, the decrease was more shown on the leaflet, where the body fat percentage had a significant change (p = 0.000). Hence, intervention using the leaflet is more effective on nutritional status changes related with BMI and body fat percentage in obese students.
HUBUNGAN ANTARA STATUS GIZI DENGAN LAMA RAWAT INAP PADA PASIEN DIABETES MELITUS TIPE 2 DI INSTALASI RAWAT INAP I ILMU PENYAKIT DALAM RSUD Dr. SAIFUL ANWAR MALANG Santoso, Savitri Pramesti; Desiana, Nur Rahma; Kusumastuty, Inggita; Restyani, Ida
Majalah Kesehatan FKUB Vol 8, No 1 (2021): Majalah Kesehatan
Publisher : Faculty of Medicine Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.majalahkesehatan.2021.008.01.5

Abstract

Salah satu permasalahan yang dihadapi oleh rumah sakit yaitu malnutrisi. Status gizi yang kurang pada pasien dapat memunculkan length of stay yang lebih lama daripada pasien yang memiliki kondisi status gizi baik. Penelitian ini bertujuan mengetahui hubungan antara status gizi dengan lama rawat inap pada pasien DM tipe 2 di  IRNA I RSUD Dr. Saiful Anwar Malang. Metode penelitian yaitu dengan cross- sectional menggunakan metode purposive sampling dan didapatkan sebanyak 30 responden Pengukuran status gizi dilakukan dengan menggunakan Indeks Massa Tubuh (IMT) dan Lingkar Lengan Atas (LILA). Hasil menunjukkan tidak ada hubungan yang signifikan antara status gizi dengan lama rawat (nilai p = 0,537). Disimpulkan bahwa tidak ada hubungan antara status gizi dengan lama rawat inap pasien DM Tipe 2 di IRNA I RSUD Dr Saiful Anwar Malang. 
High-Fat-High-Fructose Diet Decreases Hippocampal Neuron Number in Male Rats Inggita Kusumastuty; Frinny Sembiring; Sri Andarini; Dian Handayani
The Indonesian Biomedical Journal Vol 12, No 1 (2020)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v12i1.865

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BACKGROUND: Consumption of foods and drinks high in energy, fat, and/or sugar beyond the recommended quantities can cause obesity, which triggers the incidence of brain nerve cell death related to oxidative stress, high levels of tumor necrosis factor (TNF)-α and triglycerides, and low high-density lipoprotein (HDL) levels. Progressive nerve cell death causes decreasing cognitive performance. This study aims to prove that an American Institute of Nutrition committee in 1993 (AIN-93M) diet modified with high-fat-high-fructose (HFHF) can decrease the number of hippocampal neurons. A decrease in the number of hippocampal neurons indicates progressive nerve cell death.METHODS: An experimental study using a post-test control group design was carried out using male Sprague Dawley rats. Samples were selected using simple random sampling to divide them into two groups, Group I was AIN-93M-modified HFHF diet (n=14) and Group II was AIN-93M standard (n=16). The number of visible neurons was measured in the hippocampus area of Sprague Dawley rats’ brains, stained with haemotoxylin and eosin (H&E) and scanned under 400x magnification. Neurons were counted in 10 visual fields using the "Cell_Count" application.RESULTS: The data were analysed by Pearson’s correlation test using SPSS. The results show that rats in Group I had a greater weight gain and fewer neurons than those in the Group II (p=0.023, r=-0.413).CONCLUSION: The consumption of foods high in fat and fructose can cause an increase in nerve cell death, as shown by the decrease in the number of hippocampal neurons.KEYWORDS: brain nerve cells, high fat, high fructose, increased body weight
The Relationship Among Four Pillars of Diabetes Mellitus Management with Blood Glucose Levels and Nutritional Status in Middle-Aged Diabetic Adults Kanthi Permaningtyas Tritisari; Ayuningtyas Dian Ariestiningsih; Dian Handayani; Inggita Kusumastuty
Research Journal of Life Science Vol 5, No 1 (2018)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat, Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (389.582 KB) | DOI: 10.21776/ub.rjls.2018.005.01.3

Abstract

Controlling the blood sugar level of DM patients is an approach to suppress morbidity and mortality. This study aims to know the relationship of four pillars of DM management with blood glucose levels and nutritional status in patients with type 2 DM in East Java. This study is a cross-sectional study with a sample of middle-aged type 2 DM outpatients in 4 cities in East Java, Indonesia. Four pillars of management include education profile, food planning, physical exercise, and drug adherence. The statistical analysis used was Partial Least Square. The results of the study show that four pillars were not associated with fasting blood glucose (FBG) level and 2-hour PPG in the total number of respondents (p>0.005). Interestingly, dietary intake links to 2-Hour PPG in 40-50 years age group (p=0.000) and was associated with body mass index in the total number of respondents (p=0.000). Furthermore, education profile and medication also related to FBG in 40-50 years age group (p=0.000, p=0,003). In conclusion, the success of the four pillars in controlling DM is affected by age.  In 40-50 years age group, there is an influence of education profile and drug adherence on the level of FBG.
Kadar kolesistokinin laki-laki dewasa dengan konsumsi makanan siap saji khas Indonesia dan internasional Inggita Kusumastuty; Dian Handayani; Rizky Ayu Diella Calista
Jurnal Gizi Klinik Indonesia Vol 13, No 3 (2017): Januari
Publisher : Minat S2 Gizi dan Kesehatan, Prodi S2 IKM, FK-KMK UGM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijcn.17836

Abstract

Background: Fast food comes to a meal that is prepared fast and identically high in energy and fat contents since fast food is prepared using oil and fats. Excessive eating of fast food which is Indonesian typical fast foods and international fast foods will deliver obesity risk. Satiety and hunger are known as the two main keys to obesity prevention. Furthermore, Cholecystokinin (CCK) hormone is the one of bio-indicator that can indicate both satiety and hunger.Objective: The aim of this study is to determine the difference between CCK plasma level of Indonesian and international fast food.Method: A post-test only group design was done at 16 male adult subjects. This research measured CCK plasma of adult subjects with normal nutritional status whether consumed Indonesian typical fast foods and international fast foods. CCK plasma was measured by Enzyme-linked Immunosorbent Assay (ELISA) between 0-120 minutes.Results: Subjects who consumed Indonesian typical fast foods had significantly lower CCK plasma at 30,60 and 120 minutes measurement than that counterpart (p = 0.000).Conclusion: There is a different level of CCK after consuming Indonesian typical fast food and International fast food. 
Intervensi Edukasi Gizi dan Gaya Hidup terhadap Antropometri dan Faktor Resiko Sindrom Metabolik pada Dewasa Muda dengan Berat Badan Lebih dan Kegemukan Dian Handayani; Sri Andarini; Inggita Kusumastuty; Adelya Desi Kurniawati; Ilzamha Hadijh Rusda; Rahma Micho Widyanto; Eka Nanda Wulandar; Wahyu Alfyati Regina
Jurnal Abdimas Mahakam Vol. 3 No. 1 (2019): Januari
Publisher : Lembaga Penelitian dan Pengabdian Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (379.013 KB) | DOI: 10.24903/jam.v3i1.404

Abstract

Obesitas adalah peningkatan berat badan akibat asupan yang melampaui kebutuhan fisik dan skeletal yang ditandai dengan penimbunan lemak tubuh yang berlebih. Obesitas dapat meningkatkan resiko kematian. Selain hal tersebut, peningkatan indeks Massa Tubuh (IMT) berkaitan dengan tingginya tekanan darah dan terjadinya peningkatan total kolesterol menjadi salah satu faktor terjadinya resiko jantung koroner dan stroke. Kegiatan pengabdian masyarakat ini dilakukan kepada mahasiswa Jurusan Gizi Fakultas Kedokteran Universitas Brawijaya dengan tujuan memberikan pemahaman kepada mahasiwa terkait manfaat hidup sehat dengan berat badan ideal serta mencetak edukator obesitas pada mahasiswa. Metode yang digunakan adalah edukasi kepada mahasiswa terkait perubahan gaya hidup sehat serta pre dan post test dari intervensi. Hasil dari pengukuran antara parameter sebelum dan sesudah intervensi adalah terdapat perbedaan yang signifikan terhadap berat badan, IMT dan nilai VO2Max dan tidak ada perbedaan yang signifikan terhadap parameter % lemak total, % visceral fat, kadar kolesterol dan kadar glukosa darah puasa. Hal ini bisa disebabkan oleh banyak faktor seperti tingkat kepatuhan, peserta yang sedang sakit, usia dan lain-lain. Hasil kegiatan ini dapat memberi pemahaman kepada mahasiswa bahwa perubahan gaya hidup sehat dapat mempengaruhi berat badan, IMT dan nilai VO2Max dengan intervensi yang dilakukan seperti dalam kegiatan pengabdian masyarakat ini. Mahasiswa juga dapat mengetahui dinamika menjadi edukator dalam memberi edukasi kepada masyarakat umum.
Co-Authors Adelya Desi Kurniawati Adi Nugroho, Dwi Agus Putra Murdani Agustina, Mulya Alma Maghfirotun Innayah Amanda, Efina Anak Agung Gede Anom Aswin Anak Agung Gede Sugianthara Andanu Bima Saputra Anggun Faradhita Anggun Rindang Cempaka Anis Mahmudah Anis Mahmudah, Anis Arintya, Diandra Ariska, Hanisa Iis Ariyani, Anita Dwi Arliek Rio Julia, Arliek Rio Armetristi, Fannisa Asti Melani Astari Aulanni'am, Aulanni'am Ayuningtyas Dian Ariestiningsih Balqis, Rani Diana Barakatun Nisak Mohd Yusof Cahyaningrum, Aladhiana Calista, Rizky Ayu Diella Caressa, Dea Amanda Catur Saptaning Wilujeng Cempak, Anggun Rindang Chandra, Rico Budhiarta Damayanti, Fransiska Erna Della Martha Halimatussa’diah Desiana, Nur Rahma Desty Widyani, Desty DEWI ARIANI Dewi, Diva Regita Diah Ayu Puspitasari Dian Handayani Dian Handayani Dian Handayani Dian Handayani Dian Handayani Dian Handayani Dian Handayani Dian Handayani Eka Nanda Wulandar Eka Widyanti, Laras Ristati Ekawati, Laily Elsa Permata Sari Elvira Sari Dewi Emirani Falahia Etik Sulistyowati Eva Putri Arfiani Evi Tresnowati Fajar Ari Nugroho Febriani, Devi Frinny Sembiring Fuadiyah Nila Kurniasari Galuh, Glaveria Glaveria Galuh Haq, Nabila Ainul Harjoedi Adji Tjahjono Hermanto, Andrik Hidayanti, Alfiani Hidayat Sujuti Ilzamha Hadijh Rusda Intan Yusuf Habibie Irwan Hariadi, Irwan Ismail, Dina Dewi Sartika Lestari Ismi Ningtyas Iva Tsalissavrina Kanthi Permaningtyas Tritisari Kanthi Permaningtyas Tritisari Kanthi Permaningtyas Tritisari, Kanthi Permaningtyas Kawitantri, Orchidara Herning Kumboyono Kumboyono Kuncoro, Safiratuz Zahra ‘Aisy Kusumawati, Diana Kuswandari, Luh Shanti Laila, Nike Lailatul Muniro Laily Ekawati Laily Fandianty, Laily Latif, Atifa Nafia Hasantie Lega Satya Leni Budhi Harti, Leni Budhi Leny Budhi Harti Lestari, Intan Indah Lola Ayu Istifiani Malahayati, Huzaifah Maulia, Putri Hersya Muhammad Rivai Muladefi Choiriyah Munif, Badrul Muniro, Lailatul Nadhiya Aprilliani Sunarno Nafisah, Nabilahasna Nareswari, Andayu Nindy Sabrina Ningtyas, Ismi Nora Attamimi Oktania, Rizkyah Pamungkas, Akhmad Yanuar Fahmi Pekerti, Annisaa Catur Prasetyawan, Riyan Dwi Prasetyo Adi Puspa, Diah Putri, Dianita Setya Pradita Rahma Micho Widyanto Rahmawan, Fajri Andi Ratih Indah Supratiwi Restyani, Ida Retty Ratnawati Rizal, Ardian Rizky Ayu Diella Calista Roshanti, Dian Rosuli, Ahmad Rudiyanto Rudiyanto, Rudiyanto Rukia, Sera Salwa, Putri Santoso, Savitri Pramesti Satrianto, Anang Satya, Lega Setiawati, Sindi Shinta Anggraini, Shinta Silvy Kartika Rahayuningtyas Sofie Ayu Misrina, Sofie Ayu Sri Andarini Sri Andarini Sudardjo, Meilany Purnamasari Sukarlin, Sukarlin Suprapto, Ratih Paramita Supratiwi, Ratih Indah Supriyanto Supriyanto Suryanto Suryanto Titin Andri Wihastuti Toga, Erik Tri Hidayat Ulul Azmi Videlia, Videlia Wahyu Alfyati Regina Wibowo, Rizka Azhari Widya Rahmawati Yeni Intan Kusuma Dewi Affandy Yohanes Kristianto Zunita Puri Prihandini