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All Journal Journal of Food and Pharmaceutical Science Phi : Jurnal Pendidikan Fisika dan Terapan Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmiah Teknik Industri Pharmascience Artika Sistem : Jurnal Ilmu-Ilmu Teknik CIRCUIT: Jurnal Ilmiah Pendidikan Teknik Elektro JURNAL PENGABDI Jurnal Ilmu Fisika PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat JENIUS (Jurnal Ilmiah Manajemen Sumber Daya Manusia) TIN: TERAPAN INFORMATIKA NUSANTARA Atrat: Jurnal Seni Rupa Jurnal Ilmiah Wahana Pendidikan Sasambo Journal of Pharmacy J.Pelastek Style : Journal of Fashion Design Jurnal Salingka Abdimas Riset Informasi Kesehatan Jurnal Pendidikan Kesehatan (e-Journal) Blantika : Multidisciplinary Journal Journal of Food and Pharmaceutical Sciences Jurnal Akademika Kimia Jurnal Sains dan Kesehatan Jurnal Laboratorium Sains Terapan (Journal of Environmental Sustainability Management) Journal Pharmacy of Tanjungpura JPBD (Jurnal Penelitian Busana dan Desain) Dinamika Kerajinan dan Batik: Majalah Ilmiah Berita Biologi
Hadi Kurniawan, Hadi
Program Studi Teknik Industri Universitas Diponegoro
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Validation of Analytical Method for Determining Formaldehyde Levels in Imported Apples Sold in Pontianak City using UV–Vis Spectrophotometry Rizky, Gaudensius; Nugraha, Fajar; Kurniawan, Hadi
Journal of Food and Pharmaceutical Sciences Vol 14, No 2 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.23690

Abstract

The Indonesian government has implemented various efforts to protect food from biological, chemical, and physical contaminants that may endanger public health. Formaldehyde, an aqueous solution containing 37% formaldehyde, is commonly used as an antiseptic, disinfectant, and preservative for biological specimens. However, its misuse in food products, such as imported apples, remains a concern in Indonesia. This study aims to detect and measure formaldehyde levels in imported apples sold in Pontianak City by comparing peeled and unpeeled samples. Qualitative analysis was conducted using Schiff reagent color tests, while quantitative analysis employed UV-Vis spectrophotometry. The results showed the presence of formaldehyde in unpeeled imported apples, with concentrations ranging from 5.23–22.65 mg/kg (1.57–6.80 mg/serving). Meanwhile, peeled imported apples exhibited lower formaldehyde levels, ranging from 2.55–6.75 mg/kg (0.76–2.02 mg/serving) across six districts in Pontianak City. Statistical testing with the Independent Sample T-Test showed a significant distinction between peeled and unpeeled imported apples. Therefore, peeling imported apples prior to consumption may reduce potential exposure to formaldehyde. Consumers are advised to wash apples thoroughly under running water and purchase products from reliable sources to minimize the risk of contamination. Furthermore, strengthened regulatory monitoring and stricter enforcement against the illegal use of formaldehyde in food products are necessary to ensure consumer safety and protect public health.
Validation of Analytical Method for Determining Formaldehyde Levels in Imported Apples Sold in Pontianak City using UV–Vis Spectrophotometry Rizky, Gaudensius; Nugraha, Fajar; Kurniawan, Hadi
Journal of Food and Pharmaceutical Sciences Vol 14, No 2 (2026): J.Food.Pharm.Sci
Publisher : Integrated Research and Testing Laboratory (LPPT) Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/jfps.23690

Abstract

The Indonesian government has implemented various efforts to protect food from biological, chemical, and physical contaminants that may endanger public health. Formaldehyde, an aqueous solution containing 37% formaldehyde, is commonly used as an antiseptic, disinfectant, and preservative for biological specimens. However, its misuse in food products, such as imported apples, remains a concern in Indonesia. This study aims to detect and measure formaldehyde levels in imported apples sold in Pontianak City by comparing peeled and unpeeled samples. Qualitative analysis was conducted using Schiff reagent color tests, while quantitative analysis employed UV-Vis spectrophotometry. The results showed the presence of formaldehyde in unpeeled imported apples, with concentrations ranging from 5.23–22.65 mg/kg (1.57–6.80 mg/serving). Meanwhile, peeled imported apples exhibited lower formaldehyde levels, ranging from 2.55–6.75 mg/kg (0.76–2.02 mg/serving) across six districts in Pontianak City. Statistical testing with the Independent Sample T-Test showed a significant distinction between peeled and unpeeled imported apples. Therefore, peeling imported apples prior to consumption may reduce potential exposure to formaldehyde. Consumers are advised to wash apples thoroughly under running water and purchase products from reliable sources to minimize the risk of contamination. Furthermore, strengthened regulatory monitoring and stricter enforcement against the illegal use of formaldehyde in food products are necessary to ensure consumer safety and protect public health.
EVALUATION OF HEATED CHICKEN EGGSHELL POWDER AS ANTIBACTERIAL AGAINST ESBL (EXTENDED SPECTRUM BETA LACTAMASE) PRODUCING Escherichia coli: IN-VITRO AND IN-SILICO STUDIES Nugraha, Fajar; IH, Hariyanto; Kurniawan, Hadi; Nurbaeti, Siti Nani; Fajriaty, Inarah; Priady, Aldi
Berita Biologi Vol 25 No 1 (2026): Berita Biologi
Publisher : BRIN Publishing (Penerbit BRIN)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55981/berita_biologi.2026.13653

Abstract

Antimicrobial resistance (AMR) has become a critical global health concern, particularly with the increasing prevalence of Extended-Spectrum β-Lactamase (ESBL)-producing Escherichia coli. This study aimed to evaluate the antibacterial activity of heated chicken eggshell powder (HCEP) against ESBL-producing E. coli through both in-vitro and in-silico approaches. The In-silico molecular docking studies revealed that calcium diglyceroxide exhibited the strongest binding affinity toward dihydrofolate reductase –5.9 kcal/mol, suggesting disruption of folate metabolism as a potential antibacterial mechanism. Meanwhile, in vitro results demonstrated measurable antibacterial activity, with inhibition zones ranging from 6.90 to 12.36 mm and minimum inhibitory concentration (MIC) values of 1.421 µg/ml for non-ESBL and 2.842 µg/ml for producing-ESBL E. coli. The antibacterial effect was attributed to calcium oxide content, which generates reactive oxygen species (ROS) and induces a highly alkaline microenvironment. The correlation analysis showed a strong positive relationship between sample concentration and inhibition zone as antibacterial against E. coli producing-ESBL (r = 0.987). These suggest that increasing the concentration of the HCEP sample results in a larger inhibition zone. Overall, these findings highlight HCEP as a potential alternative antibacterial agent, particularly in topical applications, while also offering a sustainable approach to eggshell waste utilization.
Co-Authors Abbassyyah, Abbassyyah Ade, Putut Afani, Selly Alfisyahrin, Nur Alilatulbariza, Nailah Amalia, rizqika Ananda, Ersa Andang Firmansyah Andriayani Anjani, Ayu Paramitha Anshar, Teuku Apsanita, Wulan Ardila, Mutia Azra, Irfan Yumardi Badaria, Lailatul Dana Kurnia Syabana, Dana Kurnia Dianova, Dahlia Djuniwarti Djuniwarti, Djuniwarti Edwin Mirzachaerulsyah Eka Kartika Untari Erdatama, Fiqry Fajar Nugraha Fajjeri, Zul Fajriaty, Inarah Fauzan Romadlon Fauzi, Masyithah Fauzy, Rizal Nur Fitra, Annis Fortuna, Dhea Geraldin, Shely Jesica Goh, Sri Wahyuni Gunawan, Alvin Hakimulfaiq, Mohammad Aziz Haq, Hutama Abdillah Harahap, Muhammad R. Hari Anna Lastya Hariyanto IH Hasni, Ali Almurtadho Helmi, T. Ahmad Ilham, Nur Arifin Indri Kusharyanti Irhamni Irhamni Irhamni Irianti, Putriana Shalum Isnindar Isnindar Izzati, Alvi Karamigi, Iota Rias Karisa, Silvy Kartika, Dharsono Sony Khairunisa, Vera Khoerul Umam, Khoerul Kirom, Ikhwanul Kurniawati, Eka Lubis, Muhammad Taufan Rizka Luliana, Sri Luthfiyyah, Nabila Made Suandika MAHMUDI Masluh, Said Agil Al Maulana, Aditya Indra Mauliza, Nizar Maysitah, Maysitah Minto Basuki Mutiadiva, Utin Najini, Robby Nihayaturrofingah, Umi Nuraini, Nabila Nurmainah Nurmainah Nurmin Arianto, Nurmin Nursapni, Salma Olvi, Tea Gilda Dara Mula Pasaman, Ima Kristo Miatus Perkasa, Muhammad Rifki Podo Yuwono Priady, Aldi Putri, Syilvi K Rahim, Mutia Ramadhani, Wasiila Ratnasari, Della Rico Saputra Ridho Ananda Rindiawaty, Sri Nenden Rizky Kurniawan Rizky, Gaudensius Ropiqa, Meri RR. Ella Evrita Hestiandari Safitri, Siti Alya Saharman Gea Saifulloh, Khafiz Salam, Naufal Firdaus Abdus Sianjung, Mayesa Helena Nangdara siti hanisah Siti Nani Nurbaeti Sollehudin, Khosim Muhammad Stevia, Tessa Suptya, Irzha Putra Susanto, Amin Sutantio, Erian Suwaryo, Putra Agina Widyaswara Tanu, Yoga Thoyyiba, Azwa Tamara Varera, Reski Agus Venturini, Fernanda Aisya Wibowo, Farras Husna Widianto, Putri Anastacia Willy, Yosefa Winatha, Muhammad Dede Yuswar, Muhammad Akib Zahriah, Zahriah Zalianti, Alya Zaskia, Nayla