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LITERATURE REVIEW: TRAUMA KIMIA OKULAR DAN PENATALAKSAAANNYA Farid Hammadi; Rani Himayani; Putu Ristyaning Ayu Sangging
Jurnal Ilmu Kedokteran dan Kesehatan Vol 10, No 3 (2023): Volume 10 Nomor 3
Publisher : Prodi Kedokteran Fakultas Kedokteran Universitas Malahayati

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33024/jikk.v10i3.9460

Abstract

Trauma kimia mata merupakan suatu keadaan darurat pada mata yangmembutuhkan evaluasi dan perawatan yang segera dan intensif. Angka kejadiantrauma mata mencapai 55 juta kasus di seluruh dunia, dimana 1,6 juta kasusmengalami kebutaan, 2,3 juta kasus mengalami penurunan visus bilateral, dan 19juta kasus mengalami penurunan visus unilateral setiap tahunnya. Proporsi traumakimia mata mencapai 10–22% dari semua trauma. Metode yang dilakukan dalampenulisan literature review ini adalah menggunakan penelusuran elektronik melaluidatabase yaitu pubmeb, sciencedirect dan google scholar. Kata kunci yangdigunakan yaitu trauma kimia, okuli, dan tatalaksana. Strategi penelusuran yangdipakai pada penelitian ini merujuk pada kerangka SPIDER (Sample, Phenomenonof Interest, Design, Evaluation, Research Type). Prinsip tatalaksana pada cederakimia adalah irigasi sampai pH netral. Pada kasus cedera kimia, irigasi mata harussegera dilakukan dengan menggunakan cairan saline atau ringer laktat selama 30sampai 60 menit. Sepuluh menit setelah dilakukan irigasi, cek ulang pH dengankertas lakmus. Irigasi diteruskan hingga mencapai pH netral (pH 7,0-7,4). Jika pHnetral belum tercapai, konjungtiva forniks diswab dengan moistened cotton-tippedapplicator atau glass rod. Setelah irigasi, diberikan antibiotik profilaksis, siklopegikdan steroid tetes mata.
Perbedaan Pemberian Dosis Ekstrak Etanol Buah Adas terhadap Kadar Ureum dan Kreatinin Tikus Putih Jantan yang Diinduksi Parasetamol Nabila Shafira; Putu Ristyaning Ayu Sangging; Bagus Pratama
Jurnal Penelitian Perawat Profesional Vol 4 No 3 (2022): Agustus 2022, Jurnal Penelitian Perawat Profesional
Publisher : Global Health Science Group

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37287/jppp.v4i3.1082

Abstract

Gagal ginjal ditandai dengan meningkatnya kadar ureum dan kreatinin dalam darah. Kerusakan ginjal dapat diakibatkan oleh berbagai macam penyebab seperti infeksi, kehamilan, trauma maupun akibat efek samping obat. Gagal ginjal imbas obat merupakan salah satu penyebab tersering dari terjadinya kerusakan ginjal. Buah adas dipercaya memilki kandungan antioksidan flavonoid yang berfungsi sebagai nefroprotektor yang melindungi dari kerusakan ginjal akibat radikal bebas. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak etanol buah adas terhadap kadar ureum dan kreatinin pada tikus putih yang diinduksi parasetamol. Penelitian ini merupakan penelitian eksperimental dengan metode penelitian post-test only control group design menggunakkan 30 tikus putih galur yang dibagi dalam 5 kelompok yaitu kelompok K1 diberikan pakan standar, kelompok K2 yang diinduksi parasetamol dosis 750mg/kgBB selama 3 dari 10 hari. Pada kelompok perlakuan, tikus diinduksi parasetamol 750mg/kgBB dan diberi ekstrak etanol buah adas setiap hari dalam 10 hari dengan dosis 100mg/kgBB (P1), 200mg/kgBB (P2) dan 400mg/kgBB (P3). Pada analisis one way ANOVA terhadap kadar urea dan kreatinin didapatkan p < 0,05, sehingga disimpulkan bahwa terdapat perbedaan bermakna pada kelompok kontrol dan kelompok perlakuan. Terdapat adanya pengaruh pemberian ekstrak etanol buah adas terhadap kadar ureum dan kreatinin tikus putih jantan yang diinduksi parasetamol.
Article Review: Congenital Nasolacrimal Duct Obstruction With Massage Therapy of The Lacrimal Sac Farraz Kanya Syahra; Rani Himayani; Putu Ristyaning Ayu Sangging
Medula Vol 13 No 5 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i5.693

Abstract

Nasolacrimal duct obstruction is a disorder that is often found in children at the early age of birth. In most cases, the obstruction lies distal to the nasolacrimal duct as a result of a patent Hasner's valve. Epidemiological studies report that the prevalence of congenital nasolacrimal duct obstruction ranges from 5% to 20% in early childhood. Clinical manifestations that can occur as a result of this obstruction are in the form of epiphora or tears that don't drain properly resulting in accumulation and overflow of tears. In addition, symptoms that arise can be erythema on the periorbital skin, upper and lower eyelids due to irritation originating from reflex rubbing due to teardrops and discharge with inadequate drainage. This case can be given conservative therapy in the form of massage of the lacrimal sac which has been proven in many studies with favorable results. This therapy can be given in the absence of further complications such as mucocele or dacryocystitis. Massage therapy used since 1923 is the Crigler Technique. There is a new technique devised by a pediatric ophthalmologist, Philip, who provides new information based on his experience. This writing uses the article review method using several sources obtained from journals and books. This paper aims to determine the understanding and conservative management of congenital nasolacrimal duct obstruction so that the obstruction will disappear and prevent further complications.
Hubungan antara Kejadian Tuberkulosis Ekstra Paru dengan Kadar Limfosit dan Monosit di RSUD Dr. H. Abdul Moeloek Provinsi Lampung periode Januari 2018-Desember 2019 Raihanah Nabilah; Putu Ristyaning Ayu Sangging; Anggraeni Janar Wulan
Medula Vol 13 No 5 (2023): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i5.745

Abstract

Extra pulmonary tuberculosis (extra pulmonary TB) is a TB infection that attacks organs other than the lungs and is also a complication of TB. Adaptive immune response plays an important role in TB patients, one of which is the role of lymphocytes as antigen-antibody specificity and monocytes as phagocytosis of pathogens. The aim of this study was to determine the relationship between the incidence of extrapulmonary TB patients with lymphocyte and monocyte levels in RSUD dr. H. Abdul Moeloek Lampung Province. This research is a type of retrospective analytic observational study with a cross-sectional research design which was conducted in December 2020 levels in RSUD dr. H. Abdul Moeloek Lampung Province by looking at medical records for the period January 2018-December 2019. The sampling technique was consecutive sampling and calculated using the Slovin formula with a total sample of 103 patients. The analysis used is the chi square test. Central nervous system TB patients totaled 80 people who had lymphocytopenia 66 people (82.5%) and normal lymphocytes 14 people (17.5%), in TB lymphocytopenic patients there were 23 people who had lymphocytopenia 14 people (60.9%) and normal lymphocytes 9 people (39.1%). As for monocyte levels, there were 80 central nervous system TB patients with normal monocytes 50 people (62.5%) and monocytosis as many as 30 people (37.5%), in TB lymphadenitis patients there were 23 people with normal monocytes 12 people (52 .2%) and monocytosis in 11 people (47.8%). The results of the chi square test on lymphocyte levels with a value of p = 0.028 and monocyte levels with a value of p = 0.373, which means that there is a relationship between the incidence of extra pulmonary TB and lymphocyte levels and there is no relationship between the incidence of extra pulmonary TB and monocyte levels levels in RSUD dr. H. Abdul Moeloek Lampung Province.
Management of pterygium surgery: Limbal Conjunctival Autograft and Subconjunctival Amniotic Membrane Graft Reisyah Syahfira; Putu Ristyaning Ayu Sangging; Rani Himayani
Medula Vol 13 No 4.1 (2023): Medula - Edisi Spesial (Special Sense)
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i4.1.751

Abstract

Pterygium is one of the common ocular surface disorders. From two Greek words, the word "pterygium" has been derived: “pteryx” meaning wing and “pterygion” meaning fin. Usually, pterygium is asymptomatic apart from its appearance. Meanwhile, no special examination is needed to diagnose it, only a physical examination is needed using a slit lamp to diagnose this condition. A slit lamp for observing the eye using magnification and bright lighting. Medical treatment in modern times includes lubrication with artificial tear drops or decongestants to provide short-term comfort and a slight improvement in cosmetics. Topical NSAIDs, eye drop loteprednol, brings added comfort. Vasoconstrictive agents minimize redness and enhance the appearance and add antihistamines to the decongestant drops to help prevent the effect of histamine associated edema and itching. However, surgical treatment remains the preferred option. In patients with pterygium, the reasons for surgery are decreased vision due to visual axis encroachment, chronic pain, persistent inflammation, abnormal astigmatism, restrictive ocular motility, and cosmesis. Many surgical techniques have been used since past to present, though none is universally accepted because of variable recurrence rates. Some examples of surgery, namely the avulsion technique, Simple excision technique, The Bare Sclera Technique, Conjunctival Autograft, and Limbal Conjunctival Autotransplant (LCAT). However, combined between limbal conjunctival autograft with the adjunctive use of a prophylactic subconjunctival graft of the amniotic membrane can decrease the recurrence rate after surgery in an ethnically diverse population with a statistically higher risk for recurrence.
Pengaruh Tingkat Prokrastinasi Akademik dan Kecanduan Smartphone terhadap Prestasi Akademik pada Mahasiswa Aktif Program Studi Farmasi Universitas Lampung Pasca Pandemi Covid-19 Zayatri Nurul Jannaty; Oktafany Oktafany; Citra Yuliyanda Pardilawati; Putu Ristyaning Ayu Sangging
Jurnal Kedokteran Universitas Lampung Vol 7, No 1 (2023): JURNAL KEDOKTERAN UNIVERSITAS LAMPUNG
Publisher : Fakultas Kedokteran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.23960/jkunila71%p

Abstract

Pandemi Covid-19 pada tahun 2020 hingga 2022 banyak mengubah perilaku belajar mahasiswa. Dampaknya yaitu tingkat kecanduan smartphone naik akibat kebutuhan teknologi penunjang pendidikan yang meningkat, sehingga membuat penggunaan smartphone juga meningkat. Penggunaan smartphone di luar fungsi akademik berpengaruh terhadapmeningkatnya perilaku prokrastinasi akademik, yaitu penundaan pekerjaan dan tugas akademik. Penelitian terdahulu banyak yang telah membuktikan bahwa perilaku prokrastinasi akademik dan kecanduan smartphone memiliki keterkaitan dan mempengaruhi prestasi akademik mahasiswa. Penelitian ini bertujuan untuk mengetahui pengaruh tingkatprokrastinasi akademik dan kecanduan smartphone terhadap prestasi akademik pada mahasiswa aktif Program Studi Farmasi Universitas Lampung pasca pandemi Covid-19. Penelitian ini menggunakan pendekatan cross sectional dengan jumlah sampel penelitian sebanyak 209 responden. Alat ukur yang digunakan berupa Academic Procrastination Scale, Smartphone Addiction Scale-Short Version, dan data indeks prestasi kumulatif (IPK) dari situs akademik UniversitasLampung. Berdasarkan analisis korelasi dengan uji Rank Spearman, didapatkan bahwa tidak terdapat pengaruh bermakna antara prokrastinasi akademik dan prestasi akademik (p=0,997), serta tidak ditemukan pula pengaruh yang signifikan antara kecanduan smartphone dan prestasi akademik (p=0,137) pada mahasiswa aktif Program Studi Farmasi Universitas Lampung pasca pandemi Covid-19.  Kata Kunci: kecanduan smartphone, prestasi akademik, prokrastinasi akademik
Diagnosis dan Tatalaksana Trikiasis Keziah Tirtawijaya; Putu Ristyaning Ayu Sangging; Rani Himayani
Medula Vol 13 No 4.1 (2023): Medula - Edisi Spesial (Special Sense)
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i4.1.674

Abstract

Trichiasis is a condition in which the eyelashes are in the wrong position, facing back and rubbing against the cornea or conjunctiva. In trichiasis the eyelash follicles are normal, but the direction of their growth is abnormal. Some of the eyelashes or all of the eyelashes at the eyelid margin may be involved. Trichiasis can be classified into major and minor. Trichiasis is an acquired condition, not a congenital condition. Trichiasis affects the lower eyelids, but in certain cases, such as chemical burns of both eyelids and trachoma, the upper eyelids are more affected. The cause of trichiasis is often idiopathic, but chronic eyelid inflammation or an infection such as trachoma, herpes simplex or zoster, can be the cause. Trichiasis often occurs with other diseases such as trachoma, cicatricial pemphigoid, and other eyelid trauma. Trichiasis is complicated by corneal erosion and corneal ulcers. Trichiasis can cause eye irritation. Treatment of trichiasis is divided into operative and non-operative management. Treatment of trichiasis depends on the number of eyelashes involved. Treatment of trichiasis can be in the form of using contact lenses, removing eyelashes, or surgery. This paper uses the article review method using sources such as journals and books. The purpose of this writing is to know the definition, diagnosis, and management of trichiasis. The diagnosis of trichiasis can be established by anamnesis and physical examination. The management of trichiasis depends on the symptoms in the anamnesis and physical examination.
Hubungan Glaukoma dengan Hipertensi Muhammad Arsy Kamal Faadhil; Putu Ristyaning Ayu Sangging; Rani Himayani
Medula Vol 13 No 4.1 (2023): Medula - Edisi Spesial (Special Sense)
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i4.1.675

Abstract

Glaucoma is a group of progressive optic neuropathy characterized by degeneration of retinal ganglion cells and resulting changes in the optic nerve head. Glaucoma can be classified into 2 broad categories: open-angle glaucoma and angle-closure glaucoma. In patients with open-angle glaucoma, there is increased resistance to aqueous outflow through the trabecular meshwork. Conversely, access to drainage pathways is usually obstructed in patients with angle-closure glaucoma. Intraocular pressure can cause mechanical stress and strain on the posterior structures of the eye, especially the lamina cribrosa and the surrounding tissues.Acute open angle glaucomacan manifest itself with pain radiating from the eye, visual disturbances, conjunctival hyperemia, and occasionally nausea and vomiting with a tense, rock-hard globe. This is an ophthalmological emergency that requires immediate treatment to prevent severe eye damage and blindness. In contrast, open-angle glaucoma is usually asymptomatic until it reaches an advanced stage. If there are visual field defects, they are usually not located in the same part of the fields of the two eyes and are therefore well compensated for by binocular vision. Thus, people with open-angle glaucoma generally report no symptoms and many are completely unaware that they have the condition.Several epidemiological studies have reported that an increase in systemic blood pressure is associated with a small increase in intraocular pressure. Individuals with hypertension have a risk of about 1.2 times higher for developing open-angle glaucoma than individuals without hypertension followed by other risk factors, namely age over 40 years, and use of antihypertensive drugs. Patients over 40 years of age, especially those with a history of hypertension, are advised to undergo an eye examination.
Buta Senja: Hubungannya Dengan Asupan Vitamin A di Indonesia Evan Christian Christian; Putu Ristyaning Ayu Sangging; Rani Himayani
Medula Vol 13 No 4.1 (2023): Medula - Edisi Spesial (Special Sense)
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i4.1.679

Abstract

Night blindness is a disorder of the eyes where the eyes cannot function properly in low light or inadequate lighting conditions. This occurs due to dysfunction of the rod cells present in the retina of the eye. Rod cells play a crucial role in vision and are closely related to the availability of vitamin A in the body. Vitamin A is an essential micronutrient for the body and plays an active role in a person’s vision. Vitamin A works in conjunction with rhodopsin in the mechanism of vision. Vitamin A can produce rhodopsin and regulate vision mechanisms through several mechanisms, one of which is the conversion of the cis chain to trans. Vitamin A deficiency can disrupt a person’s vision. Research shows that there are still many children in the world and in Indoneisa who suffer from vitamin A deficiency. The WHO estimates that around 190 million children worldwide suffer from vitamin A deficiency. Studies in Central Java shows that Indonesia still experiences vitamin A deficiency, with about 60% of children having serum retinol levels below normal. Low serum retinol is indicator of a person’s vitamin A deficiency, The use of vitamin A supplements is important in preventing night blindness. Research shows that the use of additional vitamin A supplements can be done since infancy, by providing supplements to newly delivering mothers, so that the vitamin A supplements consumed by the mother can increase the retinol level in the colostrum of mother’s milk that will be consumed by the child.
Gambaran Umum dan Tata Laksana Kalazion Lintang Lestari Cahya Sawitri; Putu Ristyaning Ayu Sangging; Rani Himayani
Medula Vol 13 No 4.1 (2023): Medula - Edisi Spesial (Special Sense)
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v13i4.1.687

Abstract

Chalazion is the most common local inflammatory condition, accounting for 13.4% of all benign eyelid lesions, caused by obstruction of the meibomian glands in the upper or lower lid, either unilaterally or bilaterally. Chalazion is a chronic granulomatous inflammatory condition of the Meibomian glands which are responsible for producing meibum which can reduce tear evaporation and facilitate lubrication of the ocular surface. This situation is often associated with acne rosacea, atopy, seborrheic, and chronic blepharitis. The lesions are inflammatory nodules that form when the products of lipid breakdown enter the surrounding tissue and trigger a granulomatous inflammatory reaction. The nodule is not more than 1 cm in size, not hyperemic, not painful when pressed, not fluctuate, and pseudoptosis. Single hard textured nodule located deep in the upper or lower lid or tarsal. Management can be done through a conservative approach, antibiotics, and surgery. Conservative medical treatments include warm compresses, eyelid massage, eyelid scrubs, and eyelid cleansing with baby shampoo. Antibiotics are generally not indicated, unless the condition is associated with severe blepharitis or blepharitis due to rosacea. Persistent lesions require surgical intervention. Smaller lesions are treated by surgical curettage and dissection. Larger lesions require more extensive excision. Good sleeping habits, regular exercise, and fresh air are essential to promote healthy skin and Meibomian glands.
Co-Authors Adinda Husna Cahyana Agung Ikhssani Agustyas Tjiptaningrum Ahmad Duta Al-Ihya Alghani, Sulthan Rafi Almaina Puteri Jasmine Almaina Amira Nabila Andi Nafisah Angelica Philia Christy Anggraeni Janar Wulan Annisarahma, Lyvia Aprilia, Intan Rahma Ardian Reza Putra Arfa Salma Firnandya Ari Irawan Ari Irawan Ari Wahyuni Aulia Nur Fitriatsani Aurora Awindya Nareswari Azizah Nur Rahmah Bagus Pratama Brigitta Shinta dewi Carissa Aprilia Y Cholyviona W.S Handhayani Citra Yuliyanda Pardilawati Cut Karel Dithia Daffa Fahreiza Daffa Fahreiza Devina Hardianto Devira Fitriani Kamal Devya Aulia Dian Isti Angraini Dilla Syahra Noor Fitri Dzakwan Cedri Ketierteu Ellysa Angguman Putri Evan Christian Christian Fadila Gustiani Daraz Fadilah Alwiyah Faiq Razaan Razaan Farid Hammadi Faridi Pani Farraz Kanya Syahra Fayza Syachrani Fityah Zabrina Hidayat Ganesha Rahman Hakim Ghina Salsabila Fenty PNR Gusnirwan, Alief Hanifah Qollama Astrid Hanna Mutiara Hendri Busman Herlambang, Geri Indra Imtinan Khoirunnisa Indah Kurnia Putri Waruwu Indah Salsabila Indri Windarti Intanri Kurniati Isabela Irene Pangestu Jhons Fatriyadi Suwandi Julianti, Dinul Aliya Kalih, Abigael Ludwina Kamila Nastiti Karima, Nisa Keziah Tirtawijaya Khairun Nisa Kurnia Fithrananda Kurniawaty, Evi Laja, Rana Salsabila Putri Lintang Lestari Cahya Sawitri Mafalda Marzon Maria Devi Melni Armadani Mentari Putri Maharani Mira Yustika Mochamad Fauzan Dava Muhamad Zaidan Algifari Muhammad Ammar Naufal Muhammad Arsy Kamal Faadhil Muhammad Maulana Muhammad Rizki Akbar, Muhammad Rizki Mukhbita, Khalila Alya Mukhlis Imanto, Mukhlis Nabila Alsa Sagia Nabila Shafira Nabila Yoli Rahmadani Nadhia Wihelga Nahrassyiah Rahma Putri Ni Putu Sari Widiyani Noval Ramadirta Nurul Fadhilah Az-zahro Nurul Utami Oktafany Oktafany Oktoba, Zulpakor Pardilawati, Citra Yulianda Pardilawati, Citra Yuliyanda Prasetyo, Muhammad Purwono Qoriba, Fathan RA Genta Syakira Hatta Rachel Agustin Inggrid Zefanya Rafi Gutra Aslam rahmawati, selvi Rahmi Zuraida Raihanah Nabilah Rani Himayani Rani Himayani Rani Himayani Rasmi Zakiah Oktarlina Ratna Dewi Puspita Sari Regita Dwi M Reisyah Syahfira Rifka Putri Dewi Rika Lisiswanti Risti Graharti Rizqiani Astrid Nasution Rudiyanto, Waluyo Salsabila Haqya Kusuma Salshabilla, Annisa Sembiring, Dustin Delano Pranata Setiorini, Anggi Shiddiq, Muhammad Nasrullah Nur Shinta Nareswari, Shinta Simanungkalit, Jesica Natalia Sinulingga, Anselmus Libreya Siti Shafira Elfreda Suharmanto Suryani Agustina Daulay Susianti Susianti Sutarto Sutarto Sutyarso Sutyarso Syahrani Alya Murfi Syalwa Meutia Syiva Ulhayah Tamaulina Br Sembiring Tiasti, Jania Tri Umiana Soleha Tsurayya Fathma Zahra Yashila Rahimah Zahra, Siti Aqila Zayatri Nurul Jannaty Zheva Aprillia Yozevi