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Rizka Rizka, Rizka
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Journal : EDUNursing

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PENGARUH MAHKOTA DEWA (PHALERIA MACROCARPA) TERHADAP GLUKOSA DARAH MENCIT DIABETIK : LITERATUR REVIEW Rizka, Rizka; Khotimah, Khotimah
Jurnal EDUNursing Vol 4, No 1 (2020): April - Agustus
Publisher : Universitas Pesantren Tinggi Darul Ulum

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Abstract

Abstract Hyperglycemia that occurs in people with Diabetes Mellitus (DM) can have an impact on damage to small blood vessels, if in the long term it will cause neuropathy and disturbances in important organs in the body. Efforts that can be made to lower blood sugar levels in Diabetes Mellitus are by utilizing the crown of gods herbal plants, the alkaloid content in the crown of gods can reduce blood glucose by inhibiting glucose absorption in the intestine, increasing glucose transport in the blood, stimulating glycogen synthesis and inhibiting glucose synthesis. and increase glucose oxidation. The purpose of this study was to determine the effect of giving the crown of gods (Phaleria macrocarpa) on the blood glucose of diabetic mice. The research method was carried out by literature review by searching published journals online through the PubMed, ProQuest, Scholar and Sinta databases that met the inclusion and exclusion criteria. The results of the review of eleven reputable journals showed that the extract of the Dewa's Crown had a positive effect on reducing blood glucose levels. In the extract of the god's crown on the skin and flesh of the fruit, it contains saponins, flavonoids, alloxan compounds, and mineral or other compounds that can reduce glucose levels in the blood. Saponins and alloxans can reduce blood glucose levels by stimulating pancreatic ß cells so that insulin secretion increases and glucose decreases, and flavonoids are protective against damage to ß cells as insulin producers and can increase insulin sensitivity. Flavonoids are also helpful in regenerating islet cells of Langerhans. KeyWord : Phaleria Macrocarpa, Hiperglicemi, Diabetes Mellitus
Co-Authors Ab.Rahman, Rozanah Absori Absori Abubakar Abubakar Agam, Jumaegi Ahmad Sinala ahmad yani Aidul Fitriciada Azhari Almira, Sekar Diah Ayu Alsarandie, Fandi Amrullah, Muhammad Ilham Anwar Anwar Aprilia Aprilia, Aprilia Arfan, Fahmi Arief Budiono Arlina Arlina, Arlina Arwizet Arwizet, Arwizet Asep Mulyana Asia, Siti Nur Assegaf, S. Zulfikar Azhari, Aidul Fitricia Azizah, Isnaini Dina B.M.A.S. Anaconda Bangkara Baehaqi Bakhtiar, Arova Bangsawan, Moh Indra Bangsawan, Mohammad Indra Bashkara, Oktavian Teguh Berutu, Asro Hayati Chatarina Umbul Wahyuni Diana Setiawati Djoko Santoso Eny Purwandari Ervan Prasetyo Fadhilah, Anindia Faridy, Najihatul Finta Amalinda Firman Firman Ganadi, Yusse Putri Ghufron, Ahmad Gibran, Enrico Gibran, M Khalil hanifah hanifah Harun Harun Hayati Hayati Herdiansyah Herdiansyah Husaini Idrus M. Said Ifandri, Ifandri Ihsan Iksan, Muchammad Ilham, Ahmad Rowatul Imam Gunanjar Imron Marsyadi, Muhammad Afi Imron Rosyadi Indri Safitri, Indri Irwan Irwan Irwan Iskandar Isman, Isman Istani, Istani Junaidi Junaidi Kalsum Kalsum Kasiman, Kasiman Kelik Wardiono Khotimah Khotimah Lea Kristi Agustina Liwandika, Galang Lubis, Fitra Hidayat Lyandova, Vanka Lyandovy, Vanka M Bisri Mustofa M. Sholahuddin Manda, Darmawati Mansyur, Mauluddin Marjanah, Iramadya Dyah Marlina Marlina Mathius, Denny Mazmuloh, Hot Meilin Anggreyni Mohamad, Mohamad Mu'in, Fathul Muhamad Saleh Muhammad Idris Muhammad Junaidi Mutia, Ratna Nanang Prabowo, Gunarto Nasir Nasir Natsir, Fanda Indiana Novita Naufaldi, Muhammad Iqbal Nida, Syaima Niko Nuraini Nuraini Nurhayati , Nunik Oktafiana , Nadita Oktafiana, Nadita Padnadi, Wahyudi W. Prakoso, Bima Yuda Pramesti, Nadila Putri Prasetyo, Achmad Dzaki Putraloka, Arvico Qhoirunnisa Abdul Malik, Nur Fitri Rachmawati, Diana Widhi Rahmatun, Rahmatun Rahmi, Ince Ramdani Salam Reza Kurniawan Ridwan, Ridwan Rifai, M. Ikhsan Ririn Ririn Riska Riska Ritonga, Saprina Putri Utama Sa'diyah, Siti salamah salamah Salmande, Ali Saragih, Tuty Kurniawaty Sari, Septiana Novita Setyowati, Irlisa Sihombing, Andreas Pujian Simamora, Elisabet Ade Saputri Siti Hasanah Siti Khaulah, Siti Khaulah Siti Soekiswati Sudirman Sudirman Sulistiawati Sulistiawati Sulthanah, Sulthanah Sutanto, Vinnawaty Syamsuddin, Nurfiani Tama, Onnie Wira Toibah Umi Kalsum Tranh, Michel Lee Trias Hernanda Wardah Yuspin Warsa Warsa Waruwu, Petrus Wati, Ambar Winarti Winarti Wulandari Wulandari Yuli Setiowati Yunanto, Primadiyanti Yusup, Yusup