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All Journal International Journal of Public Health Science (IJPHS) Promotif: Jurnal Kesehatan Masyarakat Jurnal Kedokteran Anatomica (Anatomica Medical Journal) Majalah Farmaseutik Journal of Epidemiology and Public Health Indonesian Journal of Medicine Journal of Health Promotion and Behavior Oceana Biomedicina Journal INDONESIAN JOURNAL OF MEDICAL LABORATORY SCIENCE AND TECHNOLOGY JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Indonesian Journal of Global Health research AgriHealth: Journal of Agri-food, Nutrition and Public Health Maternal and Neonatal Health Journal: INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL Jurnal Impresi Indonesia Pediatric Sciences Journal Journal of Current Health Sciences AKSONA Asian Journal of Health Research CoMPHI Journal : Community Medicine and Public Health of Indonesia Journal Hang Tuah Medical Journal Prominentia Medical Journal Jurnal Adijaya Multidisiplin Journal of Pharmaceutical and Sciences. JPMP Surabaya Biomedical Journal Jurnal Kedokteran Meditek Jurnal Lentera Kesehatan Masyarakat (JLKM) Svāsthya: Trends in General Medicine and Public Health Journal of Medicine and Health Technology Surabaya Biomedical Journal
Ronald Pratama Adiwinoto
Universitas Hang Tuah
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Journal : hang tuah medical journal

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Hubungan Usia Dengan Kejadian Prolaps Uteri di Departemen Obstetri dan Ginekologi RSPAL dr. Ramelan surabaya KETUT EDY SUDIARTA; MOCHAMAD ALVIRIO NEDYA RIZKA; MUHAMMAD RIZAL; NANDA ABIGAIL; RONALD PRATAMA
HANG TUAH MEDICAL JOURNAL Vol 20 No 1 (2022): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

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Abstract

ABSTRACT BACKGROUND: Uterine prolapse is the descent of the cervix, uterus, and both adnexa from their normal position into the vagina. In general, the incidence of pelvic organ prolapse is 41-50% in women aged over 40 years and will increase with increasing life expectancy, and uterine prolaps is the second most common after cystourethrocele. The incidence of uterine prolapse patients is not known with certainty. Some studies report the incidence of uterine prolapse in the elderly, but there are also studies that report mostly at the age of 20-35 years. Therefore, we conducted a study to determine the relationship between age and uterine prolapse. METHODS: The study used a cross-sectional approach to determine the relationship between age and uterine prolapse in the Obstetrics-Gynecology ward at the Naval Center Hospital Dr. Ramelan Surabaya for the period 2019 to 2021. The data is presented in the form of tables and statistical tests using Q2-Square. CONCLUSION: In the period 2019-2021, there were 1797 cases of gynecological patients in the gynecology inpatient room and 63 cases (3.5%) of them were uterine prolapse. The highest incidence was in the age group 60-64 years with 27.0% (n=17) with distribution based on the level of uterine prolapse the most were grade 3-4 with n = 69.8% (n=44) and grade 1-2 prolapse with 30.2% (n=19). The youngest age is 35 years old and the oldest is 79 years old. Treatment of 63 cases of uterine prolapse 38 cases (60.3%) underwent surgery and 19 cases (39,7%) 9.7%) Keyword: uterine prolapse, pelvic organ, pelvic surgery, management.
Pengaruh Pemberian Ekstrak Spirulina platensis Terhadap Penurunan Kadar Serum SGPT Tikus Putih Jantan Galur Wistar yang Diinduksi Parasetamol Dosis Tinggi E.J.T, SIHNING; SAES, JOVITASARI ELVIANA PUTRI; ADIWINOTO, RONALD PRATAMA; NURDIANTO, HERU
Hang Tuah Medical Journal Vol 21 No 2 (2024): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v21i2.376

Abstract

Latar Belakang : Hepatotoksisitas akibat obat merupakan cedera hati yang dapat dipicu karena penggunaan parasetamol dosis tinggi. Metabolisme parasetamol menghasilkan metabolit reaktif NAPQI yang menciptakan kondisi stres oksidatif di hati. Spirulina platensis mengandung fikosianin yang berperan sebagai antioksidan sehingga mampu mengurangi pembentukan radikal bebas. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian ekstrak Spirulina platensis terhadap penurunan kadar SGPT tikus putih jantan galur Wistar yang diinduksi parasetamol dosis tinggi. Metode : Studi laboratorium eksperimental dengan desain post test only control group pada total 24 tikus yang dibagi kedalam 3 kelompok: (1) Kelompok K(-) diberi makanan standar selama 10 hari; (2) Kelompok K(+) diberi parasetamol dosis 1250mg/kgBB di hari kedelapan; (3) Kelompok perlakuan diberi ekstrak Spirulina platensis dosis 360mg/kgBB selama 10 hari serta diberi parasetamol dosis 1250mg/kgBB di hari kedelapan. Di hari kesepuluh ketiga kelompok diterminasi dan diambil sampel darah untuk pengukuran SGPT. Hasil Penelitian : Rerata SGPT pada kelompok K(-) 58,5 m/l, kelompok K(+) 84,8 m/l, dan kelompok perlakuan 70,7 m/l. Didapatkan perbedaan rerata kadar SGPT kelompok K(+) dan kelompok perlakuan pada p=0,082. Kesimpulan : Pemberian ekstrak alga hijau biru (Spirulina platensis) sebagai antioksidan dengan dosis 360mg/kgBB/hari selama 10 hari memperbaiki fungsi hepar khususnya dalam menurunkan kadar serum SGPT tikus putih jantan galur Wistar yang diinduksi parasetamol dosis tinggi dengan hasil signifikansi 0,082 (p>0,05). Kata Kunci: Spirulina platensis, Antioksidan, Serum glutamate pyruvate transaminase (SGPT), Rattus norvegicus
Perbandingan Efektivitas Platelet Rich Plasma VS Hypertonic Dextrose Prolotherapy terhadap Perbaikan Klinis Pasien Osteoartritis Genu POERWANTO, EKA; HENDRATA ERRY ANDISARI2; Rr. MUTIARA DEVANIA SAMARA QALBA; RONALD PRATAMA ADIWINOTO
Hang Tuah Medical Journal Vol 22 No 1 (2024): Hang Tuah Medical Journal
Publisher : Universitas Hang Tuah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30649/htmj.v22i1.639

Abstract

ABSTRACT Background: Knee osteoarthritis (OA) affects mainly older individuals, causing joint degeneration and decreased mobility. While current treatments include medications and surgery, regenerative therapies like Platelet Rich Plasma (PRP) and Hypertonic Dextrose Prolotherapy (HDP) offer promising alternatives. This study aims to compare the effectiveness of PRP and HDP injections in knee OA patients, providing insights into optimal treatment choices. Methods: This experimental analytical study involved two groups of participants. Group 1 (N=20) received PRP injections three times into both knees with four-week intervals. Group 2 (N=20) received HDP injections with 20% concentration into both knees with the same intervals. Numeric Rating Scale (NRS) and Western Ontario and McMaster University Arthritis Index (WOMAC) scores were assessed before and after injections to evaluate changes in pain, stiffness, and functional limitation. Results: Both PRP and HDP injections significantly reduced NRS scores, pain, stiffness, functional limitation, and total WOMAC scores. The reduction in pain, functional limitation, and total WOMAC scores was higher with HDP, while PRP was more effective in reducing stiffness. Mild pain during injection and knee swelling were reported by some participants, but no systemic complaints were noted, and all side effects resolved within a week. Conclusion: Both PRP and HDP injections are equally effective in reducing pain and stiffness and improving function in knee OA patients. These procedures offer promising, cost-effective, and easily administered therapies for knee OA, with HDP being a more cost-efficient option compared to PRP. Keywords: Osteoarthritis, regenerative therapy, comparison
Co-Authors Abdul Azis, Bima ADAM, OLIVIA MAHARDANI Adisyahputra, Vega Adnyana , I Made Dwi Mertha Agung Dwi Wahyu Widodo Agung Pranoto Agustin, Renny Al Hasan, Hafidz Ramadhan Alpha Fardah Athiyyah Amin, M. Shadiqul Angelica Kresnamurti ANNISA ULLYA RASYIDA Ariewibawa, Fariz Atiqi Arifin, Alief Qobidh Al Bashor Artha Budi Susila Duarsa Astrid Kusuma Avelline, Kendraadine Dheayu Baita, Etina Noor Biutifasari, Verna Brilliandinda Ichsasqia Sidqi Auliayahya Brilliant , Fahridho Ramadhana Cahya Yudha Laksmana Putra Cempakasari, Aulia da Cruz , Zito Viegas Devanda, Kasilda Pasha Dewi, I Gusti Ayu Ajeng Widia Kencana Dewindra Candra Puspita, Amalia Diah Utami, Prawesty Diana, Adawiyah Putri Diarnasa Zihara Safira, Lavenda Dinda Umardy, Fairuziah Distyvanya, Shakira Azzahra Dwinka Syafira Eljatin Dwitama Adiwinoto, Robert E.J.T, SIHNING Effendi, Muchiddin Andri Setyo Eka Fitriani Hafel Erina Yatmasari Ersanda Nurma Fathir Fadhilah, Yahdiyan Febri Endra Budi Setyawan Florentina Sustini Graciela, Anne Maria Hadi, Janto Poernomo Hadi, Rifqi Athaya Vinanta Hamdy, Irza Hasanal Hardiono Hardiono, Hardiono Hardjono, Ellen Angelique Haris, Ivana Angelica Hayati, Khofifah Bela Rachmanu Helda Dwiana Sari HENDRATA ERRY ANDISARI2 Herdiyantini, Mita Heru Nurdianto Hibatullah, Faiz Nur Hidajat, Boerhan Hutami, Firdha Yekti I Made Dwi Mertha Adnyana Izzah Al Nabilah Jongky Hendro Prajitno Kalada, Elisabeth Chelsea Uma Ketut Edy Sudiarta Kharizmatika Kurnia Cahya, Sekar Larassanti, Levina Lauwis, Keziah Queency Liliawanti Liza Yudistira Yusan Lutfian, Lutfian Made Ayu Mira Cyntia Dewi Made Peni Juliana Maliku Nurrochman Widandi Manata Wijaya Sasmita Martono, Alicia Stevina Maulana Muchammad Aunun Najib Maulana, Sidik Maylisca Theresia Mulya Diprasta, Made Medina, Nadra Odifa Meiriyanti Dhita Mentari Nata Kusuma Michael Bramantya Michelle Madeline Maydavania Miranda, Stefani MOCHAMAD ALVIRIO NEDYA RIZKA Muhammad Kalaznykov MUHAMMAD RIZAL Nadya Aisyah Sasqia Putri Nahdah, Jaudah NANDA ABIGAIL Nelya Rindayu, Dinnara Ni Luh Gede Sudaryati Norholila Nugraheni, Pramita Anindya Oki Nugraha Putra Oktavia, Reza Mardiana Ayu Peppy Nawangsasi Peter Gunawan Tandean Pikir, Rizqi Rokhmadhoni Poerwanto, Eka Pramita Anindya Nugraheni Pramudita Riwanti Prasasti, Vincentia Prasetya, Hanung Prasetyadi , Frans O.H. Prima Arundani Purmata, Andrew Theo William Chris Putra, Fabianus Yvan Marino Cahaya Putra, Oki Nugraha Putri, Fernita Naomi Putri, Ida Ayu Govinda Lazenobia De Sanjaya Putri, Jeanaya Hedya Alfara Putri, Jenniefer Clarissa Raharja, Febrila Tarisa Rahmadita, Annisa Putri Rahmawati, Tiara Rantika, Rheina Hasna Raza, Syed Meesam Renata Prameswari Retno Budiarti Retno Budiarti Riami Ristanti, Safira Roanna Gabrielle, Vania Robert Dwitama Adiwinoto Rokhmadhoni Pikir, Rizqi Rr. MUTIARA DEVANIA SAMARA QALBA Rusli, Christina S. Soedarsono Sadya Wendra SAES, JOVITASARI ELVIANA PUTRI Safira, Vita Sandy, Emy Noviana Santoso, Clara Cindy Ateng Saptono Putro Setyawan, Yuswanto Sianipar, Habel Ryan Annerico Soedarsono Soedarsono Soelistijo, Soebagijo Adi Sri Umijati STEFANUS DJONI HUSODO Sudiarta, Ketut Edy Sulistiawati Sulistiawati Sulistiawati Sulistiawati Sulistio, Timothy Sunur, Vincentius William Syahputri, Dewi Sylvia Rizki Tamam Jauhar Tasalina Yohana Parameswari Gustam Titong Sugihartono Ubaid, Angling Febriani Ariqoh Ulwani, Qulistan Balqis UNTARI, NI KOMANG SRI DEWI Usman Hadi Utami , Prawesty Diah Utami, Rina Mega Vivien Earlyanti, Callista Wahyu Prasasti Mutiadesi Wahyu Prasasti Mutiadesi Widati Fatmaningrum Widjajanto , Hendra Wijaya, Jennifer Wijaya, Rike Andy Wijayaningrum, Lena Zeeva, Evane Jovanie Zenjaya, Kellyn Trycia Zunnahri, Salsabila Qurrotul Aini