Article Per Year (5 Year)
p-Index From 2021 - 2026
5.696
P-Index
This Author published in this journals
All Journal Jurnal Kedokteran dan Kesehatan : Publikasi Ilmiah Fakultas Kedokteran Universitas Sriwijaya Jurnal Kesehatan Andalas Jurnal Penelitian Kesehatan Suara Forikes Syntax Literate: Jurnal Ilmiah Indonesia Jurnal Kesehatan Komunitas Majalah Kedokteran Andalas Majalah Patologi Indonesia Health and Medical Journal JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga International Journal of Nasopharyngeal Carcinoma Andalas obstetrics and gynecology journal Science Midwifery Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Ilmu Kesehatan Indonesia (JIKSI) Indonesian Journal of Cancer The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Jurnal Riset Ilmiah
Aswiyanti Asri
Departement Of Patology Anatomi, Faculty Of Medicine, Universitas Andalas, Padang
Humanities Biochemistry, Genetics & Molecular Biology Computer Science & IT Dentistry Economics, Econometrics & Finance Education Environmental Science Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Public Health Social Sciences Veterinary Other

Published : 68 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 68 Documents
Search

 3   4   5   6   7 
KARAKTERISTIK KLINIKOPATOLOGI KARSINOMA SERVIKS DI RUMAH SAKIT DR. M. DJAMIL PADANG  PERIODE 2018 – 2021 Fedrivia, Rannia; Asri, Aswiyanti; Elfi, Eka Fithra; Muhammad, Syamel; Mulyani, Henny; Nofita, Eka
SINERGI : Jurnal Riset Ilmiah Vol. 2 No. 5 (2025): SINERGI : Jurnal Riset Ilmiah, Mei 2025
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v2i5.1206

Abstract

Cervical carcinoma is a malignant tumor of cervical epithelial cells which is more than 90% caused by the human papillomavirus. Clinicopathology factors in cervical carcinoma such as age, history of parity, history of sexual intercourse, history of clinical manifestations, histopathology type and degree of differentiation are known to affect the prognosis. This study aims to determine the clinicopathological characteristics of cervical carcinoma at Dr. M. Djamil Hospital Padang in 2018-2021. This research is a descriptive research with the number of samples, 108 patients with confirmed cervical carcinoma. Research was conducted from March 2022 to March 2023 at the Laboratory of Anatomical Pathology, Dr. M. Djamil Padang. The results found that majority of cervical carcinoma patients is ≥45 years old (74,1%) with all patients are married (100%). The clinical manifestation that most patients complained about was vaginal bleeding 99.1% and 91,7% patients of cervical carcinoma were multiparity. The most common histopathological type of cervical carcinoma is squamous cell carcinoma (77.8%) and the highest degree of differentiation is moderate (47.2%). The cervical carcinoma patients at the Laboratory of Anatomical Pathology Dr. M. Djamil Hospital in 2018-2021 were found in the early elderly age group and are in advanced stage so it is necessary to carry out early detection and prevention of cervical carcinoma.
Penatalaksanaan Adenoma Pleomorfik Septum Nasal Danuwirya, Muhammad Reko; Rahman, Sukri; Asri, Aswiyanti
Jurnal Otorinolaringologi Kepala dan Leher Indonesia Vol. 2 No. 1 (2023)
Publisher : Fakultas Kedokteran Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jokli.v2i1.18

Abstract

Pendahuluan: Tumor kelenjar liur minor pada sinonasal relatif jarang, dilaporkan hanya 4% sampai 8% dari semua tumor sinonasal. Adenoma Pleomorfik adalah tumor jinak campuran yang terdiri dari komponen sel epitel, mioepitel dan mesenkim yang tersusun dalam beberapa variasi komponen. Diagnosis tumor ini dapat ditegakkan dengan anamnesis, pemeriksaan fisik, pemeriksaan penunjang dan pemeriksaan histopatologi. Penatalaksanaan kasus adenoma pleomorfik adalah dengan eksisi per endoskopi serta perlu dilakukan follow up untuk mendeteksi kekambuhan dan kemungkinan transformasi menjadi keganasan. Laporan kasus: Dilaporkan seorang pasien perempuan umur 46 tahun dengan hidung tersumbat sebelah kiri sejak 2 bulan sebelum masuk rumah sakit. Pada pasien ini dilakukan eksisi per endoskopi dan diikuti dengan pemeriksaan histopatologi sebagai penatalaksanaan dan konfirmasi diagnosis. Kesimpulan: Tumor jinak di kavum nasal dapat berupa adenoma pleomorfik. Penatalaksanaan eksisi per endoskopi pada adenoma pleomorfik kavum nasal yang berasal dari septum memberikan hasil yang memuaskan.
The Correlation of P16 Expression with Degree of Differentiation and Tumor Stage in Cervical Squamous Cell Carcinoma (CSCC) Sari, Nova Fenita; Nizar, RZ; Asri, Aswiyanti
Majalah Patologi Indonesia Vol. 32 No. 3, September 2023
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v32i3.653

Abstract

Background Cervical squamous cell carcinoma (CSCC) represents 70-80% of all cervical cancer cases. This cancer ranks 4th most common death cause due to malignancy in women. Cervical SCC patients were found at an older age and were detected at an advanced stage. High risk human papillomavirus (HPV) infection is main cause of SCC. Protein cyclin-dependent kinase inhibitor 2A also called p16 is a well-known tumor suppressor protein involved in cell cycle regulation, senescence, apoptosis, cell invasion and angiogenesis. This p16 protein can be used as surrogate marker for HPV infection. From several previous studies, there were differences between p16 expression relationship with differentiation degree and cervical SCC tumor stage results. Relationship research between p16 expression and differentiation degree and tumor stage of cervical SCC patients has never been conducted in West Sumatra. Methods This research was retrospective observational cross-sectional study with 35 cervical SCC cases that have been diagnosed at Anatomical Pathology Laboratory, RSUP Dr. M. Djamil Padang period January 2018-December 2019. Samples were obtained by simple random sampling from paraffin blocks derived from tumor tissue. The histopathological slide was reassessed to assess differentiation degree and tumor stage data were obtained from the patient's medical record. p16 expression in tumor cells was seen by immunohistochemical examination. To determine the correlation, bivariate statistical analysis was performed using the chi-square test with significance p<0.05 level. Results p16 high expression was found in 22 cases, tended to be higher in degree of well differentiation (40.9%) and moderate differentiation (50.0%) and was higher at an advanced stage (90.9%). Statistically, there is no correlation between p16 expression and differentiation degree with p value=0.138. There was no correlation between p16 expression and tumor stage with p value=0.337. Conclusions This study concluded that p16 expression was not associated with differentiation degree and tumor stage in cervical SCC.
Hubungan Ekspresi E-cadherin dengan Derajat Histopatologik dan Tumor Budding pada Karsinoma Endometrium Jenis Endometrioid Pemuda, Haris; Asri, Aswiyanti; Zuryati Nizar, Rachmadijah; Yetti, Husna
Majalah Patologi Indonesia Vol 31. No. 3, September 2022
Publisher : Perhimpunan Dokter Spesialis Patologi Anatomik Indonesia (PDSPA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55816/mpi.v31i3.515

Abstract

BackgroundEndometrial carcinoma is the fourth most common malignancy among women worldwide with increasing incidence and death rate every year. One of the types of endometrial carcinoma is endometrioid carcinoma, originated from atypical hyperplasia and develop into carcinoma. Lack of intercellular cohesiveness in the epithelial tumors such as endometrioid carcinoma occur due to lack of expression of E-cadherin. It can also causetumor invasion and metastatic through the epithelial-mesenchymal transition (EMT) process. Tumor differentiation and tumor budding are presumed to be histopathologic representations due to lack of cohesiveness and the occurrence of the EMT process so that these two things need to be related with the expression of E-cadherin on tumor cells.MethodsAn observational study was conducted using a cross-sectional approach with 46 cases of endometrioid endometrial carcinoma.Samples were obtained from 4 Anatomical Pathology Laboratories in West Sumatra during 2016-2019 in the form of paraffin blocks and HE slides that obtained from hysterectomy surgery. Reevaluation of tumor grade and tumor budding in HE slides was performed. E-cadherin expression in tumor cells was seen by immunohistochemical staining. Bivariate statistical analysis was performed using Fisher's Exact test and the results were considered significant if the p value was <0.05.ResultsSpecimens with negative E-cadherin expression were more common in grade 2 tumors (41.7%) and grade 3 tumors (50.0%) and in specimes with positive tumor budding (91.7%). Statistical analysis revealed a significant correlation between E-cadherin expression with tumor grade (p=0.000) and tumor budding (p=0.000).ConclusionExpression of E-cadherin has a significant correlation with the tumor grade and tumor budding in endometrioid endometrial carcinoma.
Lack of Significant Association between Stromal Tumor-Infiltrating Lymphocytes (TILs) and 2014 FIGO Stage in Epithelial Ovarian Cancer: A Cross-Sectional Study Putri, Amanda; Asri, Aswiyanti; Antonius, Puja Agung
JUXTA: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga Vol. 17 No. 1 (2026): Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Publisher : Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/juxta.V17I12026.84-89

Abstract

Highlights: Understanding the relationship between TIL infiltration and tumor stage could refine prognostic models and guide targeted therapies. Tumor-infiltrating lymphocytes density is considered an essential immune marker in ovarian cancer, but this study did not demonstrate a significant association with FIGO staging.   Abstract Introduction: Ovarian cancer is the fifth most common cancer among females. Prognostic factors such as stage and tumor-infiltrating lymphocytes (TILs) may influence outcomes. This study aimed to analyze the relationship between stromal TIL density and 2014 International Federation of Gynecology and Obstetrics (FIGO) staging in epithelial ovarian cancer. Methods: This cross-sectional analytical study included 44 cases (n=44) of epithelial ovarian cancer diagnosed at the Laboratory of Anatomical Pathology, Dr. M. Djamil General Hospital, Padang, Indonesia, in 2021–2022, selected using consecutive sampling. Stromal TIL density was evaluated on hematoxylin and eosin (HE) slides according to the International TILs Working Group guidelines and categorized as low (≤10%) or high (>10%). 2014 FIGO staging was obtained from medical records. Statistical analysis was performed using the International Business Machines Corporation (IBM) Statistical Package for the Social Sciences (SPSS) version 26, with Chi-square or Fisher’s exact test, and p<0.05 was considered significant. Results: Early-stage disease (stage I-II) comprised 25 cases (56.8%), of which 12 cases (48%) had low TIL density, and 13 cases (52%) had high TIL density. Advanced-stage disease (stage III-IV) comprised 19 cases (43.2%), of which 13 (68.4%) showed low TIL density, and 6 (31.6%) showed high TIL density. Chi-square analysis showed no significant association between TIL density and FIGO stage (p=0.295). Conclusion: No significant relationship was found between stromal TIL density and 2014 FIGO staging in epithelial ovarian cancer. Further research with larger cohorts and detailed TIL subtypes may clarify their prognostic relevance.
Hubungan Overekspresi HER2 dengan Status Reseptor Hormonal Kanker Payudara Di RSUP Dr. M. Djamil Padang Tahun 2017-2021 Aldestra, Yudha; Yenita; Khambri , Daan; Asri, Aswiyanti; Rustam, Rony; Anggraini, Fika Tri
Jurnal Ilmu Kesehatan Indonesia Vol. 7 No. 1 (2026): Maret 2026
Publisher : Fakultas Kedokteran, Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jikesi.v7i1.1519

Abstract

Latar Belakang: Overekspresi HER2 terjadi pada sekitar 10-15% kanker payudara dan cenderung mempunyai prognosis yang buruk. Reseptor hormonal terdiri dari reseptor estrogen dan reseptor progesteron. Hubungan overekspresi dari HER2 dan reseptor hormonal digunakan untuk menilai prognostik dan prediktif pada kanker payudara. Objektif: Penelitian ini bertujuan untuk mengetahui hubunngan overekspresi HER2 dengan status reseptor hormonal kanker payudara di RSUP Dr. M. Djamil Padang tahun 2017 – 2021 Metode: Penelitian ini adalah studi analitik retrospektif dengan pendekatan cross-sectional untuk mengetahui hubungan antara overekspresi HER2 dengan reseptor hormonal di RSUP Dr. M Djamil tahun 2017 – 2021. Hasil: Berdasarkan uji Chi-Square menunjukkan terdapat hubungan antara overekspresi HER2 dengan reseptor hormonal kanker payudara (p<0,05). Kesimpulan: Terdapat hubungan antara overekspresi HER2 dengan reseptor hormonal kanker payudara.
Clinicopathological Characteristics of Hepatocellular Carcinoma at a Tertiary Hospital: A Retrospective Study Rasfa, Rum Affida; Hilbertina, Noza; Asri, Aswiyanti; -, Yenita; Devianti, Loli
The Indonesian Journal of Gastroenterology, Hepatology, and Digestive Endoscopy Vol 27, No 1 (2026): VOLUME 27, NUMBER 1, April, 2026
Publisher : The Indonesian Society for Digestive Endoscopy

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24871/271202637-44

Abstract

Background: Hepatocellular carcinoma (HCC) is the sixth most common cancer globally and shows significant regional variations in clinicopathological characteristics. Limited data exist on HCC patterns in Indonesia, particularly in West Sumatra. This study aimed to characterize the clinicopathological features of HCC at Dr. M. Djamil Hospital, Padang, from 2021to2024.Methods: A descriptive retrospective study was conducted using medical records and histopathological re-evaluation of 46 HCC cases. Specimens were examined for demographic data, tumor characteristics, histopathological subtypes according to the WHO 2019 classification, differentiation grade, lymphovascular invasion, and background liver pathology.Results: The median age was 56 years, with male predominance (60.9%). Most specimens were resection specimens (60.9%) with tumor size ≥4 cm in 47.8% of cases and single nodules in 52.1%. Clear cell (39.1%) and macrotrabecular massive (37.0%) were the predominant subtypes, contrasting with global data showing NOS predominance. Most tumors were moderately differentiated (63.0%), with lymphovascular invasion present in 65.2% and cirrhotic background in 58.7% of casesConclusion: HCC in West Sumatra demonstrates distinct histopathological patterns, with a predominance of clear cell and macrotrabecular massive subtypes and high rates of lymphovascular invasion. These finding suggest histopathological features associated with aggressive tumor behavior (particularly macrotrabecular massive subtype and lymphovascular invasion), although no clinical outcome or survival analysis was performed.
PENGARUH PEMBERIAN PARE (MOMORDICA CHARANTIA) TERHADAP PERUBAHAN HISTOPATOLOGIS PADA USUS TIKUS YANG TERINFEKSI ESCHERICHIA COLI Putri, Sabrina Herfika; Tofrizal, Alimuddin; Sy, Elmatris; Asri, Aswiyanti; Rita, Rauza Sukma; Putra, Syandrez Prima
SINERGI : Jurnal Riset Ilmiah Vol. 3 No. 4 (2026): SINERGI : Jurnal Riset Ilmiah, April 2026
Publisher : Lembaga Pendidikan dan Penelitian Manggala Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62335/sinergi.v3i4.2469

Abstract

Bitter melon (Momordica charantia) has been empirically proven for antimicrobial properties that can be used as an alternative medicine, while the changes that occur in Escherichia coli-infected mouse intestine after administering bitter melon have not been widely studied. The aim of this study was to determine the effect of Momordica charantia administration on histopathology of intestine of E. coli infected mice. This research was post-test control randomized group study involving 20 mice’s small intestine paraffin blocks which were divided into 4 groups consisted of control and different dosage of bitter melon juice, observed subsequently under a microscope to measure the of the small intestine lining and assess inflammation using modified Barthel Mandja scoring. This study found significant changes the height of mucosa and villi of mice small intestine after administration of 100 grams of bitter melon juice and the muscle layer and crypts after administration of 200 grams of bitter melon juice. The Barthel Manja score showed decrease of inflammation degree among P2 group, while increased inflammation degree found in P3 group. It can be concluded that administration of bitter melon juice has the potential to improve the intestinal histopathology of mice infected with Escherichia coli.
Co-Authors -, Yenita Adrial Adrial Adrial Adrial Afriani - Afriani Afriani, Nita Aisyah Elliyanti Alan Mustaqim Aldestra, Yudha Almurdi Almurdi Andi Friadi Anggrainy, Fenty Antonius, Puja Agung Arifuddin Arifuddin Aristya Rahadiyan Budi Arni Amir Arnofyan, Budi Pratama Asril Zahari Asril Zahari Bestari Jaka Budiman Bobby Indra Utama Daan Khambri Danuwirya, Muhammad Reko Deddy Saputra Desi Aliefia Dessy Arisanti Devianti, Loli Dia Rofinda, Zelly Dia Dian Pertiwi Dini Andri Utami Dutia Gestin Dutia Gestin Edison Eka Fithra Elfi, Eka Fithra Eka Nofita Elmatris Sy Endrinaldi Endrinaldi Endrinaldi Etriyel Myh Febriyanti, Rizka Fedrivia, Rannia Fika Tri Anggraini Ginting, Desi Scorpinasari Hafni Bachtiar Hardian, Sonny Hardisman Hasmiwati Hasnaini Hasnaini Henny Mulyani henny Mulyani Hera Novianti Hera Novianti Hera Novianti Hera Novianti Hera Novianti, Hermafasya, Ayu Octarin Hirowati Ali Histawara Subroto Husna Yetti Husnil Kadri iftahillah - iftahillah Iwani Rahmah Rambe Julizar Julizar Kamelia, Muthia Karmia, Hudila Rifa Khambri , Daan Kusumardani, Dini Laila Isra Laila Isrona liana, nana Lismawati Rasyd Malinda Meinapuri Mayorita, Pamelia Meta Zulyati Oktora Miftah Irramah Mohamad Reza Muflikal Hamdi Muhamad Febry Muthia Kamelia Nabilla Mahyenda Nadhira Isza Qushoyyi Nadia Oktarina Nana Liana Nana Liana Nana Liana Nita Afriani Nizar, RZ Nova Fenita Sari Noverial Noverial Novianti, Hera Noza Hilbertina, Noza Nuzulia Irawati Oktora, Meta Zulyati Pamelia Mayorita Pemuda, Haris putri, amanda Putri, Rizqy Nurfathonah Putri, Sabrina Herfika R Zuryati Nizar R. Zuryati Nizar Rachmadijah Zuryati Nizar Rahmani Welan Rahmi Ramadhani Randi Septiah Hendri Rauza Sukma Rita Resti Aulia Fitri Rizka Fitria Husni Rosfita Rasyid Rum Affida Rasfa Rustam, Rony RZ Nizar RZ Nizar Salmiah Agus Salmiah Agus Salmiah Agus Salsabila Muslim Salsabilla Firdaus Sari, Nova Fenita Sari, Rini Purnama Selly Alinta Syukri Shofi Faiza sondang - nora Sorayya A'dilah Putri Suci Rahmadhani Sukri Rahman Susanto Winarko Syamel Muhammad Syandrez Prima Putra Teddy Kurniawan Tofrizal Tofrizal, Alimuddin Tuti Lismayarni Utami, Dini Andri Valencia Valencia Valencia Valencia Valencia, Valencia Vashti Resti Putri Firdaus Wirsma Arif Harahap Yanwirasti . Yenita . Yenita Afriyeni Yessy Setiawati Yessy Setiawati Yuastika Puspita Sari Yulistini, Yulistini Zuryati Nizar, Rachmadijah