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All Journal Pendidikan Biologi Prosiding Seminar Biologi Bioedukasi Bio-Pedagogi : Jurnal Pembelajaran Biologi EDUSAINS Prosiding Pendidikan Sains Jurnal Pendidikan Biologi Indonesia Jurnal Inovasi Pendidikan IPA Journal of Tropical Biodiversity and Biotechnology Edu Sains: Jurnal Pendidikan Sains dan Matematika Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan Jurnal Pendidikan Biologi AKSIOLOGIYA : Jurnal Pengabdian Kepada Masyarakat Jurnal Penelitian Pendidikan IPA (JPPIPA) INKUIRI : Jurnal Pendidikan IPA Biosfer: Jurnal Pendidikan Biologi Jurnal PAJAR (Pendidikan dan Pengajaran) KONSTAN - JURNAL FISIKA DAN PENDIDIKAN FISIKA Bioedukasi: Jurnal Pendidikan Biologi Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Jurnal Ilmu Peternakan dan Veteriner Tropis (Journal of Tropical Animal and Veterinary Sciences) Nusantara Science and Technology Proceedings Bioscientist : Jurnal Ilmiah Biologi Integrated Science Education Journal Proceeding Biology Education Conference Journal of Research in Instructional CITIZEN: Jurnal Ilmiah Mulitidisiplin Indonesia Journal of Educational Sciences Molekul: Jurnal Ilmiah Kimia Jurnal Inspirasi Peternakan Habitat: Jurnal Ilmiah Ilmu Hewani dan Peternakan
Meti Indrowati
Biology Education, Faculty Of Teacher Training And Education, Universitas Sebelas Maret, Indonesia
Religion Agriculture, Biological Sciences & Forestry Humanities Astronomy Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Decision Sciences, Operations Research & Management Earth & Planetary Sciences Economics, Econometrics & Finance Education Energy Engineering Environmental Science Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Materials Science & Nanotechnology Mathematics Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

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Antioxidant, Anti-Aging and Antibacterial Activity from Dewa Leaves Ethanolic Extract (Gynura japonica (Thunb.) Juel) Fatmawati, Umi; Zienitha, Anggie Meilinda; Anggraini, Meisi; Rosita, Lisa; Indrowati, Meti; Harlita, Harlita; Santosa, Slamet; Permatasari, Vera; Primahana, Gian; Yati, Indri; Prastya, Muhamad Eka
Molekul Vol 20 No 2 (2025)
Publisher : Universitas Jenderal Soedirman

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20884/1.jm.2025.20.2.13792

Abstract

ABSTRACT. Due to their phytochemical constituents, Dewa leaves (Gynura japonica (Thunb.) Juel.) are often used in traditional medicinal herbs. However, in vitro and in vivo of antioxidative and anti-aging studies of Dewa leaves on yeast as a eukaryotic cell model have not been widely carried out. This study aims to determine the antioxidant, anti-aging, and antibacterial activities derived from G. japonica leaves extract. Extraction was conducted using 70% and 96% ethanol solvents, total phenolic content (TPC) was assayed using Folin-Ciocalteu method, flavonoid contents (TFC) was assayed using aluminum chloride method, antioxidant activity was tested using DPPH (1,1-diphenyl-2-picrylhydrazyl) and ABTS (2,2-azinobis-3-Ethylbenzothiazoline)-6-sulfonic acid) radicals. Subsequently, an anti-aging activity test was performed on the yeast Saccharomyces cerevisiae as a model organism following antibacterial activity. The antibacterial activity test was carried out using well diffusion agar, and the Minimal Inhibitory Concentration (MIC) was determined using the microplate method. We obtained that G. japonica leaves extracted from 70% and 96% methanol solvents, have TPC of 13.14 and 22.11 mg GAE/gr extract, and TFC of 8.04 and 14.09 mg QE/gr extract, respectively. As for DPPH and ABTS antioxidant activity, D70 showed the best activity with IC50 values of 1411.36±56.35 µg/mL and 2516.10±18.77 µg/mL, respectively. The anti-aging test showed that both 70% and 96% ethanol extracts were able to maintain the yeast cell viability under H2O2 oxidative stress. Further, 70% and 96% ethanol extract also showed antibacterial activity at the best value against Staphylococcus aureus with a MIC value of 390.62 µg/mL, it means that Gynura leaves extract has a potency as antibacterial agent. The results of this study indicate that the ethanol extract of G. japonica leaves can be developed for further investigation as an antioxidant and antibacterial therapeutic agent. Keywords: Anti-aging, antibacterial, antioxidant, Gynura japonica, Saccharomyces cerevisiae
Pemberdayaan masyarakat melalui pembuatan produk sabun handmade dan masker wajah organik di Mipitan Mojosongo Surakarta Fatmawati, Umi; Harlita, Harlita; Indrowati, Meti; Sari, Dewi Puspita; Santosa, Slamet
Aksiologiya: Jurnal Pengabdian Kepada Masyarakat Vol 7 No 4 (2023): November
Publisher : Universitas Muhammadiyah Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30651/aks.v7i4.10469

Abstract

Penggunaan sabun cuci tangan meningkat pesat di masa pandemi COVID-19. Masyarakat disarankan untuk sering mencuci tangan dengan sabun agar bakteri dan virus yang menempel di tangan mati dan tidak menginfeksi tubuh. Berdasarkan hal tersebut maka diadakan kegiatan pelatihan pembuatan sabun bagi warga di desa Mipitan Mojosongo Surakarta. Kegiatan ini bertujuan untuk melatih masyarakat agar terampil membuat sabun handmade yang murah, aman dan berkualitas yang tidak kalah dengan sabun produksi pabrik. Kegiatan ini dilakukan dalam tiga tahap yaitu sosialisasi praktik pembuatan sabun, pelatihan pembuatan sabun, dan evaluasi kegiatan. Pelatihan dilakukan secara offline dengan tetap memperhatikan protokol kesehatan yang ketat. Produk sabun yang dikembangkan adalah sabun batang dengan aromaterapi, sabun cair antiseptik dan sabun cuci piring berbahan dasar minyak goreng bekas. Selain itu, tim P2M juga membekali warga dengan keterampilan membuat produk masker wajah organik untuk kesehatan dan perawatan kulit. Hasil evaluasi dari kegiatan ini adalah sebanyak 90% anggota masyarakat yang mengikuti kegiatan pelatihan menyatakan bahwa pelatihan pembuatan sabun handmade dan masker organik sangat bermanfaat dan tertarik untuk mengembangkan produk di pasar komersial.
ARGUMENTATION SKILLS AND SELF-REGULATION OF STUDENTS USING PROBLEM BASED LEARNING COMBINED WITH DEBATES BASED ON SOCIOSCIENTIFIC ISSUES ON ENVIRONMENTAL CHANGE MATERIAL Widyastuti, Anie Yuni; Harlita, Harlita; Indrowati, Meti
EDUSAINS Vol. 16 No. 1 (2024): EDUSAINS
Publisher : Faculty of Education and Teacher Training, UIN (State Islamic University) Syarif Hidayatul

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15408/es.v16i1.34823

Abstract

Lack of self-confidence and self-monitoring to think, act and communicate scientifically are related to argumentation skills. This study aimed to determine differences: (1) students' argumentation skills, (2) students' self-regulation, (3) argumentation skills and students' self-regulation using Problem Based Learning (PBL) combined with debates based on Socio-scientific issues (SSI) on environmental change material. The method used is a quasi-experiment with a posttest only control group design. The population in this study was class X SMA N 2 Karanganyar 2022/2023, and the sample used was class XE2 and class XE7. The sample technique used is cluster random sampling. Collecting data on argumentation skills uses a test, while collecting data on self-regulation uses a questionnaire. The data analysis technique used the t test and teh manova test. It was concluded that there were significant differences: (1) students' argumentation skills, (2) students' self-regulation, (3) argumentation skills and students' self-regulation using Problem Based Learning (PBL) combined with debates based on Socio-scientific issues (SSI) on environmental change material. The research results can be used as a reference related to PBL learning, debate method, argumentation skills and students’ self-regulation abilities
Teknik perbanyakan tanaman buah dan tanaman hias secara vegetatif untuk meningkatkan pendapatan masyarakat di era pandemi Fatmawati, Umi; Harlita, Harlita; Indrowati, Meti; Sari, Dewi Puspita; Santosa, Slamet
Jurnal Inovasi Hasil Pengabdian Masyarakat (JIPEMAS) Vol 5 No 1 (2022)
Publisher : University of Islam Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33474/jipemas.v5i1.13726

Abstract

Di masa pandemi saat ini, animo masyarakat mengenai budidaya tanaman buah dan tanaman hias meningkat tajam. Selain untuk menyalurkan hobi, budidaya tanaman buah dan tanaman hias juga dapat meningkatkan pendapatan masyarakat dengan memasarkan produk ke pasar. Harga per pot tanaman buah dan tanaman hias melonjak di masa pandemi, dan juga permintaan pasar yang cukup tinggi. Tujuan dari kegiatan ini adalah memberikan pengetahuan dan keterampilan teknik budidaya tanaman buah dan tanaman hias secara vegetatif seperti stek, cangkok, menyambung/grafting dan tunas kepada mitra dan memberikan informasi mengenai prospek bisnis dan strategi pemasaran tanaman buah dan tanaman hias di Kampung Mipitan Mojosongo Surakarta. Selain itu juga dilakukan pendampingan pemasaran produk tanaman hias dan tanaman buah yang dikembangkan secara vegetatif. Metode yang dilakukan adalah dengan sosialisasi, workshop/pelatihan, dan monitoring. Beberapa jenis tanaman buah yang dikembangkan secara vegetatif adalah tanaman jeruk, jambu air, belimbing dan mangga dengan cara cangkok dan stek. Sedangkan tanaman hias yang diperbanyak secara vegetatif adalah tanaman yang memiliki nilai ekonomi tinggi seperti aglaonema, euphorbia, dan anggrek. Hasil kegiatan ini sebanyak 90% orang peserta menyatakan bahwa pelatihan perbanyakan tanaman memberi manfaat dan pengetahuan untuk membudidayakan tanaman buah dan hias serta mengembangkannya menjadi prospek wirausaha.
Molecular Docking of Gamma Amino Butyric Acid GABA on Rattus Norvegicus B-receptor as Antidiabetic Indrowati, Meti; Harlita; Fatmawati, Umi; Ariyanto, Joko; Retnaningtyas, Estu
Jurnal Penelitian Pendidikan IPA Vol 10 No 7 (2024): July
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v10i7.8044

Abstract

Earlier research reported that GABA had a correlation with diabetes in processes of glucose homeostasis. This study aims to identify the validity of B-receptor Rattus norvegicus as GABA protein target, modeling the structure and knowing the binding affinity between GABA and B-receptor Rattus norvegicus through molecular docking.   The research was carried out using in-silico method.  The interaction of GABA with the target protein was determined using SuperPred, followed by modeling the protein target using SwissadMe. Ramachandran Plot and Errat Procheck are used to determine the validity of the protein target. Molecular docking was determined using Pyrx and PyMol. The results showed that GABA binding to the B- receptor Rattus norvegicus has biological activity as glucose oxidase inhibitor and antidiabetic.  The conclusion are: B-receptor Rattus norvegicus is a valid protein target for binding to GABA; there are four 3-dimensional models of B-receptor Rattus norvegicus and the best model has 98.43% sequence identity; the binding affinity of GABA (ligand) on B-receptor Rattus norvegicus from the best model is -3.4 kcal/mol energy, 1.773 RMSD lower bound, and 1.81 RMSD upper bound. It is suggested that this research might be used as an empirical basis to further investigate GABA as antidiabetic.
A Deep Learning–Based Electronic Module for Global Warming: An Analysis of Validity and Readability to Support Critical Thinking Skills Razak, Ziyana Walidah; Muzzazinah, Muzzazinah; Indrowati, Meti
Integrated Science Education Journal Vol 7 No 1 (2026): January
Publisher : Cahaya Ilmu Cendekia Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37251/isej.v7i1.2480

Abstract

Purpose of the study: This study aims to analyze the validity and readability of a deep learning–based electronic module (e-module) designed to improve students’ critical thinking skills on global warming material. Methodology: The research employed a Research and Development (R&D) approach using the ADDIE model, consisting of analysis, design, development, implementation, and evaluation stages. The developed e-module integrates deep learning principles—mindful, meaningful, and joyful learning—into a Google Sites platform and is enriched with multimedia elements, including videos, animations, interactive worksheets, Padlet, and a carbon footprint calculator. The validity of the e-module was evaluated by six experts, including media experts, subject matter experts, and linguists, using Aiken’s V formula. Main Findings: The results showed that all validation aspects achieved Aiken’s V values ranging from 0.83 to 1.00, exceeding the minimum validity threshold (V > 0.78), indicating that the e-module is highly valid. Readability testing involved ten junior high school students and two science teachers and was analyzed using percentage-based criteria. The readability scores ranged from 88% to 100%, categorized as excellent across content, format, presentation, and language aspects. These findings indicate that the deep learning–based e-module is not only valid but also highly readable and user-friendly. Novelty/Originality of this study: The developed e-module has strong potential to be implemented as an innovative digital teaching material to support science learning and foster students’ critical thinking skills, particularly in addressing contextual and global environmental issues such as global warming.
Validity Analysis of Guided Inquiry-based E-Module for Learning Hydrostatic Pressure Siti Muslikatin; Bowo Sugiharto; Meti Indrowati
Jurnal Penelitian Pendidikan IPA Vol 11 No 8 (2025): August
Publisher : Postgraduate, University of Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29303/jppipa.v11i8.11648

Abstract

This study aims to analyze the level of validity of the guided inquiry-based e-module on the material of liquid pressure as a teaching material that supports the active involvement of students in the learning process. The research method used is the research and development method (R&D) with a development model that refers to the 4D model (Define, Design, Develop, and Disseminate), limited to the development stage. The validity assessment instrument is ini the form of a validation sheet filled out by four experts, consisting of material experts, media experts, and learning experts. The aspects assessed include the appropriateness of the content, language, presentation and graphics. The validation results show that the developed e-module obtained an average score of 91% from media experts, 89% from material experts, 94% from language experts, and 92% from learning experts. Based on the research results of media experts material experts, and learning experts, it can be concluded that the guided inquiry-based e-module with an average rating of 92% is in the “very valid” category, making it suitable for use as a teaching material in science learning, especially on the topic of liquid pressure. These findings indicate that the guided inquiry-based e-module can be an innovative in improving the quality of science learning in junior high schools.
Comparison of the Growth and Development of Green Spinach (Amaranthus hybridus L.) under Soil Conditions from the Java and Kalimantan Regions Shafira, Riannisa'a; Hastuari, Fitria Alfiyah; Andayani, Anindya Aulya; Role, Rofina Mbale; Indrowati, Meti
Bioscientist : Jurnal Ilmiah Biologi Vol. 14 No. 1 (2026): March
Publisher : Department of Biology Education, FSTT, Mandalika University of Education, Indonesia.

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33394/bioscientist.v14i1.19533

Abstract

This study aimed to compare the growth of green spinach (Amaranthus hybridus L.) cultivated in two different soil types originating from Java and Kalimantan, and to examine the effect of soil pH on plant height. The experiment was conducted over a 21-day period (3–24 November 2025) using a comparative experimental design with a total of eight samples, consisting of four plants in each treatment group. The parameters observed included soil pH, plant height, number of leaves, leaf width, and leaf color. Environmental variables—such as light intensity, water volume, pot size, and seed quantity—were controlled to ensure consistent experimental conditions. The data were analyzed using statistical assumption tests, including the Shapiro–Wilk normality test and Levene’s homogeneity test, followed by linear regression analysis and analysis of covariance (ANCOVA). The results indicated that the data were normally distributed (p = 0.328) and homogeneous (p = 0.575). Regression analysis showed that soil pH had a significant effect on plant height (p = 0.026), whereas soil type did not have a significant effect after controlling for soil pH (ANCOVA, p = 0.089). The mean difference in plant height between soils from Java and Kalimantan was 2.90 cm; however, this difference was not statistically significant. These findings suggest that the growth of green spinach—particularly plant height—is more strongly influenced by environmental factors, especially soil pH, than by differences in soil origin.
Analysis of Initial Profiles of Students' Creative Thinking Skills in Biology Learning Widiyaningsih, Tutut; Adi Prayitno, Baskoro; Indrowati, Meti
Citizen : Jurnal Ilmiah Multidisiplin Indonesia Vol. 6 (2026): SPECIAL ISSUE: Sustainable Innovation at the Intersection of Economics, Technology, L
Publisher : DAS Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53866/jimi.v6i1.1251

Abstract

This study aims to analyze the initial profile of high school students' creative thinking skills in biology learning. The research is descriptive quantitative research using an open-ended test method. The subjects of this study were tenth-grade high school students. The results of the analysis show that the average creative thinking skills of high school students is 37.85%, which is classified as not creative. Specifically, the lowest percentages were found in the aspects of originality, elaboration, and flexibility, while the aspect of fluency showed relatively higher achievements. The conclusion of this study is that the profile of students' creative thinking skills in biology learning is low. These findings indicate that the dominance of convergent learning through closed questions and student passivity in class are factors that inhibit the development of divergent thinking potential. Therefore, it is necessary to apply active learning models and use more exploratory evaluation instruments to stimulate students' ability to produce unique, flexible, and in-depth ideas.
Co-Authors A.A. Ketut Agung Cahyawan W Abrari Nur Aan Ilmi Achrudin Achrudin Adhi Nurcholis Ali, Lalu Usman Alvi Rosyidi Alvi Rosyidi Amalia Ulfa Andayani, Anindya Aulya Andinawati Dwita Karina Anggita Widya Nugroho Anggraini, Meisi Anggun Nopitasari Annisa Nur Khasanah Baehaqi Baskoro Adi P Baskoro Adi Prayitno Baskoro Adi Prayitno Bowo Sugiharto Bowo Sugiharto Bowo Sugiharto Bowo Sugiharto Bowo Sugiharto Budi Hartanto C. J. SOEGIHARDJO C.J. SOEGIHARDJO Cindyana Putri Puspita Hapsari Dedy Setiyawan Dewi Puspita Sari Dewi Puspita Sari Dewi Puspita Sari Dewi Puspita Sari Dewi Puspita Sari Dian Rizki Kusuma Amalia Diska Evi Liana Diska Evi Liana Dwi Oetomo Dwi Oetomo DWITO PURNOMO Dwito Purnomo Eni Rahayu ESTU RETNANINGTYAS N Fatiha, Alifia Ninta Feni Andriani Fitriyana Rachmah G. Bramintha Pakartiar Hantyan Galih Tri Rukmana Harlita Harlita Harlita Harlita Harlita Harlita Harlita Harlita Harlita Hastuari, Fitria Alfiyah Heru Nurcahyo Heru Nurcahyo Ihda Nuria Afidah Ika Lailatus Sangadah Irfana Fauziah Irsyadah, Naeli Joko Ariyanto Joko Ariyanto Joko Ariyanto Joko Aryanto KUMAYA AGUSTINA Kusnia Patmawati Kusumawardani, Kusumawardani Laksmi, Monika Lintang Lilis Eka Herdiana Lilis Eka Herdiana Malvin Prima Soyoga Maridi - - Maridi Maridi Maridi Maridi MARIDI MARIDI MASRUROH, ROILA DEWI Muhamad Yutam Soleh Murni Ramli Muzayyinah Muzayyinah Muzayyinah Muzayyinah Muzayyinah Muzayyinah Muzazzinah, Muzazzinah Muzzazinah Muzzazinah Muzzazinah Muzzazinah Muzzazinah Nanang Riyadi Nurmiyati - - Nurmiyati Nurmiyati Nurmiyati Nurmiyati Nurul Faiqoh Nurul Qomariyah Nurzahra, Vakha Yulia PANDU HARYO WIBOWO Pandu Haryo Wibowo Permatasari, Vera Pramudita, Ayu Prastya, Muhamad Eka Primahana, Gian PUGUH KARYANTO Puguh Karyanto Puguh Karyanto Rahayu Rahayu Rahayu Rahayu RARAS IKA YULIANTI RARAS IKA YULIANTI Rarastoeti Pratiwi Ratna Dewi Kusumawati Razak, Ziyana Walidah Resi, Damasus Nosi RIEZKY MAYA PROBOSARI Riezky Maya Probosari Rika Dian Kurniawati Role, Rofina Mbale Roro Putri Nur Azmi Saputra Wijaya Rosita, Lisa Rumiyati, Rumiyati Sajidan Sajidan Sajidan Sajidan Sarwanto Sarwanto Septiyanto, Arifin Setyawati Handayani Shafira, Riannisa'a Siti Muslikatin SITI NURJANAH Siti Nurjanah Slamet Santosa Slamet Santosa Slamet Santosa Slamet Santosa Slamet Santosa Slamet Santosa Sri Dwiastuti Sri Lestari Sri Martina Wiraswati Sri Septianti Suciati Suciati Suciati Sudarisman Suciati Sudarisman Sulastri - - Suranto Suranto Susanto, Mardomo Sutarno Taufik Widhiyantoro Dwi Saputro TJAHJADI PURWOKO TJAHJADI PURWOKO Tuti Rahayu Ulfa, Amalia Umi Fatmawati Umi Fatmawati Umi Fatmawati UMI FATMAWATI Vita Anggun Cahyani Wahyu Kodrat Listianthy Widha Sunarno Widha Sunarno Widiyaningsih, Tutut Widyastuti, Anie Yuni yati, indri Yudi Rinanto Yunita Rahmawati Zienitha, Anggie Meilinda