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All Journal Majalah Kedokteran Bandung Medula Juke Jurnal Ilmu Kedokteran dan Kesehatan Review of Primary Care Practice and Education (Kajian Praktik dan Pendidikan Layanan Primer) JK Unila (Jurnal Kedokteran Universitas Lampung) Jurnal Anestesi: Jurnal Ilmu Kesehatan dan Kedokteran Jurnal Riset Ilmu Kesehatan Umum dan Farmasi JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia JPM (Jurnal Pengabdian Masyarakat) Ruwa Jurai Jurnal Agromedicine Unila: Jurnal Kesehatan dan Agromedicine
Intanri Kurniati
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Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Education Environmental Science Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences

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Journal : Medula

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Nutrional Management in Chronic Kidney Disease Patients: Manajemen Gizi pada Pasien Chronic Kidney Disease (CKD) Al Farisi, Ahmad Fathin; Kurniati, Intanri; Hadibrata, Exsa
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.982

Abstract

Chronic Kidney Disease (CKD) is kidney function disorder for >3 months. CKD is also a concern because of its relatively high prevalence and is one of the most common causes of death in Indonesia. A number of treatments that can be carried out in CKD patients depend on the symptoms, comorbidities, and complications in the patient. Management of CKD patients can be medical, operative, to conservative. Assessment of nutritional status is also a concern in patients with CKD because it is not uncommon for a decrease in nutritional status to occur. CKD patients undergoing dialysis treatment are more prone to experience protein-energy wasting (PEW). There are a number of nutritional therapies that can be performed on CKD patients, namely a low-protein diet, regulation of energy intake, oral supplementation, and IPPN/IPAA
Manajemen Terapi Acute Kidney Injury (AKI) Suherman, Auriva Renasha; Kurniati, Intanri; Hadibrata, Exsa
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.983

Abstract

Acute Kidney Injury (AKI) is a syndrome characterized by decreased urine production and increased serum creatinine. AKI is a complication in 10 to 15% of patients in hospital and the incidence of AKI in the Intensive Care Unit (ICU) is 20 to 50%. AKI has 3 stages and based on etiology it is divided into 3, namely pre-renal, renal, and post-renal. AKI can be a complication of disease and can cause complications up to end-stage kidney disease. Biomarkers of AKI are not only a guide in diagnosis, but also a guide in the management of AKI. Prevention and management of AKI needs to be carried out in patients. Several AKI treatments that can be carried out include the administration of isotonic crystalloid, Hydroxerthylstarch, vasopressors, diuretics, vasodilators, GF intervention, glycemic control, and nutritional support.
Diagnosis And Treatment of Testicular Torsion Hilmi, Tamadar; Kurniati, Intanri; Hadibrata, Exsa
Medula Vol 14 No 3 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.987

Abstract

Testicular torsion is an urgent medical condition that occurs when one or both testicles experience rotation or reversal in the scrotum, thereby disrupting blood flow to the testicles. Testicular torsion usually occurs in young male patients (<25 years). If this occurs it can cause rapid testicular ischemia. Furthermore, if ischemia is not treated immediately, it can threaten the safety of the testicles and affect men's reproduction and quality of life. This disease causes 10% to 15% of acute scrotal disease in children, and causes an orchiectomy rate of 42% in boys undergoing testicular torsion surgery. This article discusses testicular torsion, including definition, symptoms, diagnosis, and management. Testicular torsion is characterized by complaints of pain, swelling and/or tenderness in the scrotum, loss of cremaster reflex, Deming's sign and Angell's sign. Apart from that, we will also discuss early detection techniques for testicular torsion, such as physical examination and ultrasound, which are very important for diagnosing this condition quickly. Testicular viability decreases significantly 6 hours after the onset of symptoms therefore early diagnosis is key. Immediate treatment with manual detorsion or surgery is necessary to restore blood flow to the testicle affected by torsion. Delay in action can cause permanent damage to the testicular tissue. Since testicular torsion is a very time-sensitive diagnosis, it may also be subject to many medicolegal challenges.
The CORRELATION BETWEEN NEUTROPHIL LYMPHOCYTE RATIO WITH DEATH IN CORONAVIRUS DISEASE 2019 PATIENTS AT RSUD DR. H. ABDUL MOELOEK LAMPUNG PROVINCE Tibar, Fifi Nurliza Aini; Kurniati, Intanri; Rahmawati, Selvi
Medula Vol 14 No 7 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i7.1052

Abstract

World Health Organization (WHO) declared Coronavirus Disease 2019 (COVID-19) a pandemic as of March 9, 2020. Data as of October 8, 2021 recorded a total positive case of COVID-19 in Lampung Province were 49,304 cases with 3,790 deaths. Disease progression in COVID-19 patients was determined based on the results of laboratory tests. Several studies reported that the value of Neutrophil Lymphocytes Ratio (NLR) was strongly associated with clinical worsening and even death in COVID-19 patients. This study was purposed to determine the relationship between NLR with death in COVID-19 patients. This study was an observational analytic study with a cross sectional design. The sample was medical record data taken from 44 COVID-19 patients who survived and 44 COVID-19 patients who died in March 2020 - September 2021 at Dr. RSUD. H. Abdul Moeloek Lampung Province. The sample was selected using purposive sampling technique. Statistical analysis was performed by univariate and bivariate analysis. The result of the bivariate analysis with chi quare test showed the p value was 0.000 (p<0.5), which indicated that there were a relationship between NLR with death in COVID-19 patients at RSUD Dr. H. Abdul Moeloek Lampung Province. There were a statistically significant relationship between NLR with death in COVID-19 patients at RSUD Dr. H. Abdul Moeloek Lampung Province. 
Characteristics of Thyroid Carcinoma Patients at Dr. H. Abdul Moeloek Hospital for the Period of January 2023 – August 2024 Qurani, Istiqomatul; Septiani, Linda; Kurniati, Intanri; Windarti, Indri
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1333

Abstract

Thyroid carcinoma is the most common cancer found in the endocrine system that arises from thyroid parenchymal cells.  Its prevalence has increased over the past few decades with a mortality rate of 0.5% per 100,000 cases. The incidence of thyroid carcinoma in 2020 ranks 7th in the world as the 9th most frequent incidence occurs from all types of cancer. Objective: This study aims to determine the characteristics of thyroid carcinoma patients at Dr. H. Abdul Moeloek Regional General Hospital for the period of January 2023 – August 2024. Method: This study used a descriptive observational design and Total Sampling technique with a data source in the form of secondary data on medical records from 82 thyroid carcinoma patients at the Dr. H. Abdul Moeloek Regional General Hospital for the period January 2023 to August 2024.  Results: In this study, thyroid carcinoma patients were mostly female, with an age group in the range of 41-60 years. The most common type of thyroid carcinoma is papillary carcinoma and the least common type is anaplastic carcinoma. Conclusion: In this study, the characteristics of thyroid carcinoma patients were obtained based on gender, age group, and type of histopathological diagnosis.
Rasio Platelet dan Sel Darah Putih: Implikasinya dalam Patofisiologi Stroke Azhar, Hafidz Sirojudhin; Kurniati, Intanri; Pramesona, Bayu Anggileo; Utama, Winda Trijayanthi
Medula Vol 14 No 9 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i9.1454

Abstract

Acute ischemic stroke is a leading cause of morbidity and mortality worldwide, significantly impacting patients' quality of life and healthcare systems. Understanding prognostic factors that predict clinical outcomes in acute ischemic stroke patients is crucial, especially with the rising prevalence of risk factors such as hypertension, diabetes, and dyslipidemia. Recent studies have focused on hematological biomarkers, particularly the platelet-to-white blood cell ratio (PWR), which reflects the interaction between immune system components and hemostasis. This literature review examines the prognostic value of PWR in acute ischemic stroke, correlating higher PWR with better clinical outcomes measured by the National Institute of Health Stroke Scale (NIHSS). Lower PWR values have been associated with increased mortality risk within 90 days post-stroke. The dynamics of PWR provide insights into the body's response to ischemia and inflammation, highlighting its potential as a valuable prognostic marker. While PWR shows promise as a prognostic tool, limitations such as individual variability in inflammatory response, timing of measurement, and lack of standardization must be considered. Further research is needed to explore PWR's potential across diverse populations and address existing limitations to enhance its clinical application in managing acute ischemic stroke.
Potensi Ekstrak Kulit Nanas (Ananas comosus) Sebagai Antimikroba Sinaga, Herman Fransiskus; Apriliana, Ety; Septiani, Linda; Kurniati, Intanri
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1427

Abstract

Pineapple is one of the traditional plants that may be used as an alternative treatment to reduce pathogenic microbes. Its content is rich in chlorine, iodine, phenol and the enzyme bromelain which functions to stop microbial growth. This research aims to determine the potential of pineapple peel extract (Ananas comosus) as antimicrobe agents. This research uses a literature review study method, namely by using research articles obtained through a literature search process related to the potential use of pineapple peel extract on microbe from 2015 to 2025. Pineapple peel extract contains the main compounds, namely flavonoids, polyphenols, bromelain and saponins. This content causes pineapple skin extract (Ananas comosus) to have an effect on microbes.
Tinjauan Pustaka: Pengaruh Hipertensi Kronis pada Ibu Hamil terhadap Kejadian Preeklampsia Putri, Morica Angellia Shyama; Kurniati, Intanri; Putri, Giska Tri; Kurniawati, Evi
Medula Vol 15 No 1 (2025): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v15i1.1458

Abstract

Chronic hypertension in pregnant women is a medical condition that can significantly affect maternal and fetal health. Chronic hypertension is defined as high blood pressure that has been present before pregnancy or diagnosed before 20 weeks of gestation. Risk factors that affect this condition include older maternal age, obesity, family history of hypertension, and an unhealthy lifestyle. The pathophysiology of chronic hypertension that progresses to preeclampsia involves endothelial dysfunction, which causes vasoconstriction and decreased placental perfusion, leading to placental hypoxia and increased oxidative stress, which further triggers activation of systemic inflammatory pathways causing damage to target organs such as the kidneys (proteinuria) and liver (elevated liver enzymes). The prevalence of chronic hypertension in pregnant women in Indonesia is quite high. According to data from the Lampung Provincial Health Office in 2018, hypertension in pregnancy caused 15.16% of maternal deaths. In addition, data from Riskesdas 2018 shows that the prevalence of hypertension in pregnant women in Indonesia is 6.18%, with the highest prevalence in West Java Province at 10.57%. The purpose of this article is to provide a better understanding of the effect of chronic hypertension in pregnant women on the incidence of preeclampsia. This article will discuss the association of chronic hypertension with the risk and underlying mechanisms of preeclampsia.
Pengaruh HbA1c Terhadap Profil Lipid pada Pasien Diabetes Melitus Tipe 2 Suci, Maghfirly Juniarti Eka; Tjiptaningrum, Agustyas; Setiawan, Gigih; Kurniati, Intanri
Medula Vol 14 No 8 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i8.1263

Abstract

Diabetes Mellitus (DM) is characterized by a state of hyperglycemia due to insulin resistance, decreased insulin production, or both of these conditions which are classified into metabolic diseases. When checking the condition of type 2 DM, HbA1c can be checked as an indicator. High and uncontrolled HbA1c levels will cause disturbances in lipid profiles such as increased triglycerides, LDL, total cholesterol, and decreased HDL. The purpose of this study is to determine whether or not there is an effect of HbA1c on lipid profiles in type 2 DM patients. This method uses scientific publication search media such as Google Scholar, Pubmed, and old medical scientific journals using the keywords “lipid profile, HbA1c, type 2 diabetes mellitus, and dyslipidemia” obtained 15,700 articles and scientific journals. In patients with type 2 diabetes mellitus, glycemic control can be determined by HbA1c examination, high HbA1c levels are associated with disruption of lipid profile levels. The results of the study discuss the effect of HbA1c levels on lipid profiles in patients with type 2 diabetes and determine the relationship between the two.
Hubungan Protein Urin dengan Berat Jenis Urin pada Pasien Nefropati Diabetik Putri, Najwa Naraniya; Kurniati, Intanri; Yuningrum, Hesti; Susianti
Medula Vol 14 No 12 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i12.1273

Abstract

Diabetic nephropathy is one of the main causes of end-stage renal failure or End Stage Renal Disease (ESRD) in patients with type 2 diabetes. Diabetic nephropathy is defined as the presence of albumin or protein of more than 30 mg/day in urine on two examinations within a period of 3-6 months, as well as a decrease in the glomerular filtration rate. Urinalysis examination using the dipstick method is carried out for certain indications or suspicions of complications of diabetes mellitus, one of which is diabetic nephropathy. Dipstick examination can detect protein, pH, glucose, specific gravity, ketones, urobilinogen, nitrite, blood, bilirubin, and leukocyte esterase. The specific gravity of urine depends on the concentration of glucose, urea, and protein particles in the solution. Therefore, the purpose of this study was to determine the relationship between protein in urine and specific gravity in patients with diabetic nephropathy. Observational analytical research was conducted with a cross-sectional approach. This study was conducted at the Medical Records Installation of Dr. H. Abdul Moeloek Hospital. The population of this study was diabetic nephropathy patients treated at Dr. H. Abdul Moeloek Hospital in January-December 2023. The sampling technique used the total sampling technique so that 49 samples were obtained that met the inclusion and exclusion criteria. The data obtained were analyzed using the Spearman correlation test. The results showed a correlation coefficient (r) of 0.589 and a significance p-value = 0.000. There is a relationship between urine protein and urine specific gravity in diabetic nephropathy patients.
Co-Authors Ade Yonata Ade Yonata, Ade Afifah, Ighra Agustya Tjiptaningrum Agustyas Tjiptaningrum Agustyas Tjiptaningrum Al Farisi, Ahmad Fathin Al Ghifari, Ghaza Ahmad Alyssa Fairudz Shiba Andriani, Silvia Angelia, Tisa Anggraeni Janar Wulan Anggraeni Janar Wulan, Anggraeni Janar Aprilia, Sandrina Audy Ardika, Okta Besti Arif Yudho Prabowo Arisqan, Ferdian Syukri Armadani, Melni Audah, Kholis A. Azhar, Hafidz Sirojudhin Baehaqi Bagus Pratama Bayu Anggileo Pramesona Chanief Hassan Widjaja Chicy WIdya Morfi Dalillah, Fathian Nur Damayanti, Putri Deborah Natasha Dewi Nur Fiana Dian Isti Angraini Diana Mayasari Ety Apriliana Evi Kurniawati Evi Kurniawati, Evi Fadhlurrahman, Fadhlurrahman Febilla Naili Alfalah Ferry Mulyadi Fidha Ramayani Giska Tri Putri Hadibrata, Exsa Helmi Ismunandar Hendri Busman Hilmi, Tamadar Indah Salsabila Indri Windarti Intan Kusumaningtyas Iswandi Darwis Jausal, Anisa Nuraisa Jhons Fatriyadi Suwandi Jonathan Rivaldo Gultom Kamila Salsabila Karima, Nisa Kenos Stefanus Khairun Nisa Kurniawaty, Evi Maharani, Denisa Marcellia, Selvi Muhammad Ricky Ramadhian Muhammad Yusran Muhartono Muhartono Nasution, Salwa Salsabila Ni Made Shanti Novita Carolia Nurrahma, Alya Nabila Nurul Utami Oktadoni Saputra Putri, Morica Angellia Shyama Putri, Najwa Naraniya Putu Ristyaning Ayu Qurani, Istiqomatul rahmawati, selvi Rana Noor Fakhira Siregar Rani Himayani Ratna Dewi Puspita Sari Ratna, Maya Ganda Rengganis Wardani, Dyah Wulan Sumekar Reni Zuraida Risal Wintoko Risti Graharti Rizki Hanriko Rizky Agung Purnomo Roro Rukmi Windi Perdani, Roro Rukmi Salsabila, Kamila Sangging, Putu Ristyaning Ayu Septia Eva Lusina Septiani, Linda Setiawan, Gigih Sinaga, Herman Fransiskus Siti Maharani Suci, Maghfirly Juniarti Eka Suharmanto Suherman, Auriva Renasha Susianti Susianti, Susianti Syazili Mustofa TA Larasati Tibar, Fifi Nurliza Aini Tutik Ernawati Utari Gita Mutiara Vira Katya Aurelia Winda Trijayanthi Utama, Winda Trijayanthi Worocahyo, Avis Meyvika Wulan, Anggraini Janar Yuningrum, Hesti