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ANTI-INFLAMMATORY EFFECT OF LEAF ETHANOL EXTRACT OF CAT'S KUMIZE (Orthosiphon stamineus Benth) IN MALE WHITE RATS OF WISTAR STRAINS Meyana Marbun; Dian Permata Nasution; Beta Hanindiya; Mustaruddin; Yulia Delfahedah; Arsiaty
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 3 (2021): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v3i.244

Abstract

The cat's whiskers plant is empirically used by the community for the treatment of gout and rheumatism. This research was conducted with the aim of knowing the anti-inflammatory power of cat's kumis (Orthosihon stamineus Benth) leaf extract. This study was a quasi-experimental study with a one-way completely randomized design. Kumis Kucing leaf extract was extracted using 70% ethanol. A total of 25 male wistar rats aged 2-3 months, weighing 150-200g were divided into 5 groups. Each group was treated orally with distilled water (negative control), diclofenac sodium 2.25 mg/kg BW (positive control). Kumis leaf ethanol extract tested at doses of 123, 245 and 490 mg/kgBB. Treatment 1 hour before the feet of rats were inflamed with 1% sublantar carrageenin. Measurements of the rat's foot volume were carried out every 0.5 hours for 6.5 hours. The obtained average edema volume curve is used to calculate AUC (Area Under The Curve) and the obtained AUC is used to calculate DAI (Anti-Inflammatory Power). The AUC and DAI data were tested statistically with one way Anava and followed by LSD with a 95% confidence level. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded 33.11%; 52.64% and 64.12% respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively. The results showed that the ethanol extract of Kumis Kucing leaves had an anti-inflammatory effect on male white rats of the Wistar strain. Kumis Kucing ethanol extract at doses of 123, 245 and 490 mg/kg BW yielded percent anti-inflammatory properties of 33.11%; 52.64% and 64.12%, respectively.
UTILIZATION OF TURMERIC RHIZOME EXTRACT (Curcuma domestica v.) AS A DYE IN HAIR DYE PREPARATIONS Meyana Marbun; Arsiaty Sumule; Yulia Delfahedah; Muharti Sanjaya; Dilla Sastia Mara
International Conference on Health Science, Green Economics, Educational Review and Technology Vol. 4 (2022): International Conference on Health Science, Green Economics, Educational Review and T
Publisher : Universitas Efarina

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.54443/ihert.v4i.246

Abstract

Hair coloring preparations are cosmetic preparations used in hair cosmetology to color hair, either to restore the original hair color or another color. Turmeric rhizome contains alkaloids, flavanoid tannins and essential oils. The purpose of this study was to determine the chemical compounds contained in turmeric rhizome, to make turmeric rhizome change the color of gray hair. Hair dye preparation is made with a formula consisting of a concentration of turmeric extract rhizome, namely 20%. This research method is experimental by using maceration method. Physical evaluation carried out included homogeneity test, irritation test, color stability test against sun exposure, color stability test against washing. The results of this study indicate that turmeric rhizome extract can affect the color of the gray hair obtained. The stability test against washing can last for 5 times washing, the stability test against sunlight shows that the hair turns darker than before.
Co-Authors Adrian K Tarigan Afriyanti Sihombing Alijah, Alijah Amanda Sahfitri Amanda Sahfitri Andreas Andreas Anggraini, Sry Apriana, Lina Arsiaty Arsiaty Arsiaty Arsiaty Sumule Arsiaty Sumule Arthauly Gracia Sinaga Astri Ulina Saragih Beta Hanindiya Beta Hanindiya Boas Nicoyono Pasaribu Br Barus, Rovina Br Saragih, Jumadiah Wardati Caroline Tambunan, Bionitha Deswidya Hutauruk Deswidya S Hutauruk Devi Yuliani Luming Dian Permata Nasution Dian Permata Nasution Dilla Sastia Mara Dilla Sastia Mara Dilla Sastri Mara Dilla Sastri Mara Diyah Ayu Anggriani Eka Saudur Renaldi Sihombing Eka Saudur Sihombing Elsida Aritonang Emi Sugesti Emi Sugesti Emi Sugesti, Emi Fairu, Nur Love Suci Febiola, Marcellyn Febiola, Marcelyn Febriani, Winda Friani, Sri Rahma Fricilia, Dini Ginting, Cici Pratiwi Habeahan, Emika Yesi Haloho, Elia Hekdin Marsius Sipayung Hendri Kurniawan Herawati, Noni Ida Widiawati, Ida Indri Nurhabibah Irwandi Isma Oktadiana Ismi Noer Fadilah Ismi Noer Farida Ismi Noer Farida Jesita Pratiwi Siagian Juliana Siboro Jumadiah Wardati Jumadiah Wardati Br Saragih Keysha Iszmi Erhan Keysha Iszmi Erhan Lestari, Vika Ayu Lily, Cut Marbun, Lilis Oktavia Marolop Parlindungan Napitu Marolop. P. Napitu Marsius Sipayung, Hekdin Maswan Daulay Muharti Sanjaya Muharti Sanjaya Muliati Muliati Muliti Muliti Mustaruddin Mustaruddin Mustaruddin Nababan, Octavian Nababan, Octavian A. Nikmatul Khasanah Novida Ariani Nur Masdalifah Nurdian, Rubi Nurun Nisa Octavian Ashindo Nababan Oktadiana, Isma Oktafiana Manurung Purba, Desi Marliani Putri Handayani Ria Lusi Utami Riada Pasaribu Riada Pasaribu Romauli Pakpahan Romauli Sihaloho Salim Efendi Salim Efendi, Salim Samosir, Wilson Santy Widya Purba Saputri, Agnes Saputri, Retno Esti Sari, Awanda Fusvita Setianto, Rony Shofian Syarifuddin Siagian, Jesita Pratiwi Sijabat, Yulia Wandani Sipayung, Hekdin Situmorang, Dorlan Sondang Sidabutar Sri Rahma Friani Sri Rahma Friani Sri Wahyuni Tarigan Srirahma Friani Sumule, Arsiaty Sumule, Arsiyati Syahfitri, Latifah Tambunan, Morina Tiara Tampubolon, Reni Oktavia Tarigan, Adrian K Taufik Hidayat Thowilla, Lailan Titin Wahyu Toberni S. Situmorang Tri Sanjaya Ummi Umayyah Wilson Samosir Wilson Samosir Wilson Samosir Yeni Trisna Purba Yolanda Yolanda, Yolanda Yulia Delfahedah Yulia Delfahedah Yunda Pita Sari Simbolon Zendrato, Ferawati