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All Journal Jurnal Biologi Tropis Window of Health : Jurnal Kesehatan Journal Syifa Sciences and Clinical Research (JSSCR) AMALIAH: JURNAL PENGABDIAN KEPADA MASYARAKAT Jurnal Dunia Farmasi Jurnal Ilmiah Manusia dan Kesehatan PREPOTIF : Jurnal Kesehatan Masyarakat Jurnal Aisyah : Jurnal Ilmu Kesehatan Journal of Pharmaceutical and Health Research International Journal Of Science, Technology & Management (IJSTM) Indonesian Journal of Chemical Science and Technology Jurnal Kesehatan Tambusai Jurnal Farmasi dan Sains Indonesia (JFSI) Jurnal Buana Farma Indonesian Journal of Pharmaceutical Education JUKESHUM: Jurnal Pengabdian Masyarakat FORTE JOURNAL Jurnal Farmanesia Journal of Health and Medical Science International Journal of Health and Pharmaceutical (IJHP) Student Scientific Creativity Journal Cross-border Jurnal Pengabdian West Science FARMASAINKES Nusantara Scientific Medical Research Journal Usada Nusantara: Jurnal Kesehatan Tradisional Jurnal Ilmu Kesehatan dan Gizi Journal of Pharmaceutical and Sciences. Scientica: Jurnal Ilmiah Sains dan Teknologi FASKES : Jurnal Farmasi, Kesehatan, dan Sains Medic Nutricia : Jurnal Ilmu Kesehatan Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Indonesian Journal of Science and Pharmacy Jurnal Bakti Nusantara Jurnal Sains dan Kesehatan As-Salam: Journal Islamic Social Sciences And Humanities
Gabena Indrayani Dalimunthe
Program Studi Farmasi, Fakultas Farmasi, Universitas Muslim Nusantara Al-Washliyah, Medan, Indonesia
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Formulasi eyeshadow kombinasi umbi bit (Beta vulgaris L.) dan rimpang kunyit (Curcuma longa L.) dalam perbandingan ekstrak dan nanoekstrak Sihotang, Laura Indah Restu; Dalimunthe, Gabena Indrayani; Lubis , Minda Sari; Yuniarti, Rafita
Journal of Pharmaceutical and Sciences JPS Volume 7 Nomor 4 (2024)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v7i4.723

Abstract

Eyeshadow is an eye cosmetic that contains coloring agents to color effects and change the appearance. Some eyeshadow products use synthetic dyes that have a negative impact, so it is important to use safe dyes such as beetroot to produce a red color and turmeric rhizome to produce a yellow color. Turmeric rhizome yellow color. Nanoparticle-based cosmetics have advantages and can penetrate cell walls more effectively. This study aims to determine whether beetroot and turmeric rhizome extracts meet the requirements of nano extracts. Nano extracts determine the color difference at each concentration in the extracts and nano extracts as colorants for eyeshadow preparations, and choose the color of the extracts and nano extracts in eyeshadow preparations with certain concentrations that can meet the physical quality and favored by panels. This research method is True Experimental, and the research design used is a post-test-only control group design. The research design used was a post-test-only control group design. Independent variables are variations in the concentration of the combination of extracts and nano extracts of beetroot and turmeric rhizomes and eyeshadow formulations of various concentrations. Turmeric rhizome and eyeshadow formulations of multiple concentrations. The dependent variables are simplicity characteristics, phytochemical screening, particle uniformity characteristics, nano extract, and various tests. Nano extracts and various physical quality inspection tests of eyeshadow. The results showed that the beetroot and turmeric rhizome extracts met the requirements of nanoextracts with a particle size of beetroot 261 nm and turmeric rhizome 203 nm. Eyeshadow preparations containing a combination of beetroot and turmeric rhizomes in extracts and nano extracts have different colors: F1 is pink, F2 is light brown, F3 is Salem peach, F4 is peach pink, F5 is brown, and F6 is Salem pink. All eyeshadow preparation formulas meet the physical quality requirements, and F5 and F6 are the most preferred formulas for volunteers because they provide attractive colors.
Formulasi sediaan patch dari ekstrak etanol daun laban (Vitex pinnata L.) sebagai antiinflamasi Rahmi , Ulfa; Dalimunthe, Gabena Indrayani; Yuniarti , Rafita; Rani , Zulmai
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.749

Abstract

Laban leaves (Vitex pinnata L.) contain flavonoids, saponins, tannins, and steroids, which have anti-inflammatory potential. This research aims to formulate laban leaves into an anti-inflammatory patch preparation for the back skin of mice induced by 3% carrageenan. Laban leaf simplicia was extracted using the maceration method using 96% ethanol, and patch preparations were made with varying extract concentrations of 5, 7.5, and 10%. The patch preparation is tested organoleptic, pH, weight uniformity, patch thickness, patch moisture, patch crease resistance, and irritation. The anti-inflammatory activity of the patch preparation was analyzed using the inflammatory associate edema method, namely measuring the anti-inflammatory effect using a caliper and 25 test animals, which were divided into 5 groups, namely negative control, positive control, and treatment group with a concentration of 5; 7.5; and 10% with 5 individuals each. The results of several tests that have been carried out are analyzed using the one-way ANOVA program. The results show the anti-inflammatory activity of laban leaves. There was no difference in the percentage of edema inhibition data on the back skin of mice between treatment groups. This shows that the anti-inflammatory patch preparation of Laban leaf extract (Vitex pinnata L.) has anti-inflammatory activity. The formula that provides the most potent anti-inflammatory activity is a patch preparation with an extract concentration of 10%. With an edema inhibition percentage of 59%. 
Formulasi orally disintegrating tablet dari serbuk kembang kol (Brassica oleracea var. botrytis L.) dengan variasi konsentrasi sari tapai sebagai disintegrant Lestari, Sri Indah; Dalimunthe, Gabena Indrayani; Lubis, Minda Sari; Nasution, Haris Munandar
Journal of Pharmaceutical and Sciences JPS Volume 8 Nomor 1 (2025)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v8i1.773

Abstract

Cauliflower (Brassica oleracea var. botrytis L.) has a nutritional content consisting of calcium, magnesium, potassium, phosphorus, and low saturated fat. It has vitamin C, which helps increase body immunity. Orally Disintegrating Tablet preparations can dissolve quickly when placed on the tongue, formulated for ease of use of drugs for patients who have difficulty swallowing. Therefore, disintegrants are very important in ODT preparations. Tapai extract has a sweet, slightly sour taste and disintegrates immediately when placed on the tongue. This research aimed to determine whether cauliflower powder with tapai extract disintegrants can be formulated into ODT preparations and which formulation is the best.  This research included characterization of simplicia, making pre-formulation by mixing all ingredients, evaluating pre-formulation, and tablet printing by direct compression method. Then, the tablet evaluation was carried out. The disintegrant was tapai extract with 5%, 7.5%, and 10% concentrations. Data were analyzed using the One Way ANOVA method. The results of the formulation evaluation, the flow time test obtained <10 seconds, which is easy to flow; the angle of repose test obtained 26˚, the category is very good; and the compressibility test obtained 18-20%, which is quite good. The results of the tablet evaluation in the organoleptic test obtained round tablets, sweet taste, brownish-white color, and distinctive odor. The weight uniformity test on all formulas did not have any deviating weights; the size uniformity test met the requirements, the hardness test obtained 1-3 kg, the friability test obtained 0.4-0.7%, the petri dish disintegration time test obtained 44.07-52.48 seconds, and the mouth disintegration time test obtained 53.07-57.78 seconds and the wetting time test obtained 53.21-54.87 seconds. The best formula is formula 3, with a 10% tapai extract concentration.
Co-Authors Adani, Bazlina Adela Octi Dwiyani Adli Nuzula Rahmah Agustina, Meri Ahmad darwis Alma Dhita Shafira Anny Sartika Daulay Anugrah, Bayu Arianti, Sellin Arina Ashar, Diya Asparyzha, Rhyzha Aulia Fitri, Aulia Aulia, Meisyah Bambang Hermanto Basaniah Basaniah Chairina Milda Chandra, Putra Cindy Marlina Tambunan Claudy Friesta Melanie Cut Erika Maulydya D Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang Debi Meilani Dena, Mutia Dewa, Fasca Dikki Miswanda Dina Sri Novita Dina Veranika Dinda Sari Utami Dison Silalahi, Alistraja Emmy Wiriandini Fadhilah M, Ihsan Fadillah, Nike Fathur Rahman Febiyani, Rica Fithri Pulungan, Ainil Fitri Febriani Fitri, Raissa Ginting, Ovalina Sylvia Br. Girsang, Raflika Azwanda Gita Dwi Puspa Fadillah Hamda, Haikal Handayani, Riska Haris Munandar Nasution Hasibuan , Fika Miah Sasmitha Hendraputra, Hardy Handoko Heru Adha Prayogo Humairah, Dwina Angelina Husna, Miftahul husna, nadiatul Ilmi Widya Sari Isnaria, Vita Jurida, Wike Juwita, Sukma Karlina Butar Butar Kartika, Dinda Dwi Khairil Pahmi Khairunnisa , Ardina Kiki Rawitri Latifah Sahara Pulungan Lestari, Amanda Putri Lestari, Seri Lestari, Sri Indah Linda, Rosa Lisa Amalia Lubis, Minda Sari M. Arya Wiguna Madani Sirait maghfirah, Suci Mambang, D Elysa Putri Mambang, Elysa Putri Misna Rosalinda Hutabarat Muhammad Amin Nasution Muhammad Ricky Ramadhian Muhammad Tegar Tri Rizky Mutiara Rahmah Nasution, M. Pandapotan Nasution, Nur Sahadah Nasution, Shamila Sufi Aulia Nasution, Vevi Sarah Nia Novranda Pertiwi Nindya Indah Damayanti Ningtias, Anggitha Niswa, Khairun Novita Sari, Helsa Nur Asia, Nur Nur, Hijrotun Nuraisyah Nurfadilla, Kiki Nurliansyah, Nurliansyah Nurmala, Dewi Nurul Haliza Lubis Nurul Hidayah Nurul Salsa Abya Ritonga Olita, Apen Peri , Peri Peri, Peri Puteri, Cut Intan Annisa Rafita Yuliarti Rafita Yuniarti Rafita Yuniarti Rahma Dona Rahma Maulidia Fitri Rahmi , Ulfa Rambe, Robiatun Rambe, Sitiapsah Rangkuti, Cindy Rahayu Rawitri, Kiki Riani, Nur Aslin Ricky Andi Syahputra Ricky Andi Syahputra Ridwan Taher Lubis Ridwanto Ridwanto Rima Marwarni Rina Azhari Risnayanti Ritonga, Oktavia Riza Syafira Robiatun Rambe Rosalinda Mahdalena Sinaga Rosalinda Mahdalena Sinaga sahrianti, Hikmah Samosir, Anzly Hasian Samran, Samran Saragih, Aqilah Mutmainnah Sari Lubis , Minda Sari Lubis, Winda Sari, Syilvi Rinda Sartika Daulay, Anny Savika, Anggraini Selvicahyani, Selvicahyani Shinta Mida Ariani Harahap Sihotang, Laura Indah Restu Silvia Sinaga, Rosalinda Mahdalena Siregar, Hikmatussabaria Siti Anisa Siti Anisa Sitinjak, Iyustri Ririn Situmorang, Lusi Grasia Sri Mulia Ningsih Siregar Sri Wahyuni Sri Wahyuni Sulaiman Riadi Sulwiyatul K Sani Syahputri, Maulida Syarifah Aulia Syarifah Mauliza Tasya Ardana Ummu Safura Sirait Wardah Tulail Nadila Widya Sari Winda Aulia Yayuk Putri Rahayu Yayuk Putri Rahayu Yuli Apriani Br.Lubis Yuni Sartika Yuniarti , Rafita Yuniarti, Rafita Yuniarti, Rapita Zahara, Anisa Zahira Ahmad, Madani Ziza Putri Aisyia Fauzi Zulmai Rani