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Evaluation of the Antihyperuricemia Activity of Bajakah Tampala Stem Ethanol Extract (Spatholobus littoralis Hassk.) in Male White Mice (Mus musculus) Nurul Hidayah; Gabena Indrayani Dalimunthe
NSMRJ: Nusantara Scientific Medical Research Journal Vol. 1 No. 1 (2022): NSMRJ: Nusantara Scientific Medical Research Journal
Publisher : Nusantara Scientific Medical

Show Abstract | Download Original | Original Source | Check in Google Scholar | Full PDF (517.883 KB) | DOI: 10.58549/nsmrj.v1i1.28

Abstract

Hyperuricemia is elevated blood uric acid. Blood uric acid can harm health. Allopurinol can lower uric acid, but it has harmful side effects. The community has treated various diseases with Bajakah stems. This study examined Bajakah Tampala stem ethanol extract secondary metabolites and antihyperuricemia activity. This research identified the bajakah tampala stem plant (Spatholobus littoralis Hassk.), manufactured simplicia, characterized simplicia, phytochemically screened, prepared the ethanol extract, and tested its antihyperuricemia activity against male white mice (Mus musculus). The simplicia and Bajakah tampala stem ethanol extract contained flavonoids, tannins, steroids/triterpenoids, alkaloids, and saponins. At 400 mg/kgBB (3.88 mg/dl), the bajakah tampala stem ethanol extract reduces uric acid at the 6th hour, similar to allopurinol at 10 mg/kgBB (3.46 mg/dl).
PEMANFAATAN SARI LIDAH BUAYA (Aloe vera (L.) Burm.f.) DALAM SEDIAAN HARD CANDY M. Arya Wiguna; Minda Sari Lubis; Gabena Indrayani Dalimunhe; Rafita Yuliarti
Cross-border Vol. 6 No. 2 (2023): JULI-DESEMBER
Publisher : Lembaga Penelitian Dan Pengabdian Masyarakat Institut Agama Islam Sultan Muhammad Syafiuddin Sambas Kalimantan Barat

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

One of the medicinal plants that have medicinal properties is aloe vera. The development of the use of aloe vera as a food and beverage ingredient is related to the chemical composition of aloe vera which is very good for body health. One of the utilization efforts is to extract or take the juice and process it into hard candy. Hard candy (candy) is a form of processed food from heating a mixture of sugar and fruit juice or food additives to give flavor. The purpose of this study was to formulate hard candy with aloe vera juice as the main ingredient by varying the concentration of aloe vera juice in order to get a good formula in terms of taste and physical evaluation of hard candy.is Hard candy made using the oven pan. The research method used is experimental research. This study used aloe vera juice as a sample, and it was formulated into a hard candy preparation and evaluated including organoleptic tests, hardness tests, soluble time tests, tests, ash content tests, water content tests, pH tests and tests of preference level ( hedonic test) by respondents and then the results are presented descriptively. The results showed that aloe vera juice was formulated into hard candy preparations with a concentration variation of 2.5%; 5%; 10; provide an attractive shape, taste and hardness are quite good, have a pH of 5-6 and meet the requirements of water content with a coefficient of variation of 0.91%; 0.87%; and 0.89% ash content 0.99%; 0.99% and 0.99%. The results of the preference level test show that formula 1 is the best formula that is widely preferred with variations in the content of aloe vera juice. Variations in aloe vera juice content have an influence on the level of liking.
Analisis kadar vitamin C pada buah naga putih (Hylocereus undatus) dan buah naga merah (hylocereus polyrhizus) dengan perbandingan metode spektrofotometri uv dan titrasi iodimetri Claudy Friesta Melanie; Gabena Indrayani Dalimunthe; Ridwanto; Fathur Rahman
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.216

Abstract

Dragon fruit is natural source of antioxidants. We can consume not only dragon fruit flesh, but the skin is also very beneficial for health, in reality it is only considered as waste that has not been used properly. This study aims to analyze the levels of vitamin C in white dragon fruit and red dragon fruit with a comparison of uv spectrophotometry and iodimetric titration methods. The stages of the research included extracting from dragon fruit, screening phytochemicals, testing levels of vitamin C using iodimetric titration, testing levels of vitamins using UV spectrophotometry. The results showed that red dragon fruit contains alkaloids, flavonoids, saponins, tannins, triterpenoids and glycosides, while white dragon fruit contains alkaloids, flavonoids, saponins and steroids. Determination of vitamin C levels by iodimetric titration method on red dragon fruit skin was 9.240 ± 3.029 mg, on red dragon fruit flesh was 11.587 ± 1.893 mg and vitamin C levels on white dragon fruit skin was 9.827 ± 3.933 mg, on white dragon fruit flesh was 13.347 ± 3.143 mg in 100 gram sample. While the spectrophotometric method obtained vitamin C levels in white dragon fruit flesh, namely 332.93 mg/100g, in red dragon fruit flesh, 24.99 mg/100g, while red dragon fruit skin, which was 16.59 mg/100g, in white dragon fruit skin, namely 10.47 mg/100g.
EFEKTIVITAS ANTIBAKTERI EKSTRAK ETIL ASETAT DAUN GAMAL (Gliricidia sepium (Jacq.) Kunth) TERHADAP BAKTERI Propionibacterium acnes dan Escherichia coli Dina Veranika; D. Elysa Putri Mambang; Gabena Indrayani Dalimunthe; Rafita Yuniarti
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 3 No. 1 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v3i1.2373

Abstract

Daun gamal (Gliricidia sepium (Jacq.) Kunth) mengandung senyawa fenolik dan metabolit sekunder yang memiliki efek antibakteri. Tujuan dari penelitian ini adalah untuk mengetahui metabolit sekunder yang terdapat pada serbuk simplisia dan ekstrak etil asetat daun gamal, serta mengkaji potensi antibakteri ekstrak tersebut terhadap bakteri Propionibacterium acnes dan Escherichia coli. Teknik yang digunakan adalah teknik eksperimental yang meliputi preparasi sampel, pemeriksaan makroskopis, pemeriksaan mikroskopis, karakteristik sampel, skrining fitokimia, pembuatan ekstrak, dan pengujian efektivitas antibakteri dengan metode difusi cakram. Data dari pengukuran diameter daya hambat dianalisis secara statistik dengan Uji ANOVA, dilanjutkan dengan uji Kruskal-Wallis dan uji Duncan. Hasil pemeriksaan makroskopis menunjukkan daun berwarna hijau tua, lonjong, pangkal membulat, ujung runcing, panjang 7–9 cm dan lebar 3–4 cm. Hasil pemeriksaan mikroskopis serbuk simplisia menunjukkan kristal kalsium oksalat berbentuk prisma, rambut penutup uniseluler dan stomata anisositik. Hasil karakteristik simplisia menunjukkan kadar air 8%, kadar sari larut air 29,78%, kadar sari larut etanol 19,9%, kadar abu total 3,9%, dan kadar abu tidak larut asam 1,4%. Skrining fitokimia positif adanya alkaloid, flavonoid, tanin, saponin, steroid, dan glikosida. Hasil uji efektivitas antibakteri ekstrak etil asetat menunjukkan bahwa konsentrasi ekstrak 70%, 80%, 90%, dan 100% merupakan konsentrasi yang efektif menghambat pertumbuhan bakteri Propionibacterium acnes, dan konsentrasi 80%, 90%, dan 100% merupakan konsentrasi yang efektif menghambat pertumbuhan bakteri Escherichia coli, dengan nilai signifikansi p=0,006 (p<0,05). Berdasarkan hasil penelitian disimpulkan bahwa ekstrak etil asetat daun gamal memiliki aktivitas antibakteri pada bakteri Propionibacterium acnes dan Escherichia coli.
ISOLASI AMILOPEKTIN DARI PATI JAGUNG (Zea Mays L) YANG BERPOTENSI SEBAGAI FILM COATED PADA TABLET Siti Anisa; Gabena Indrayani Dalimunthe; Minda Sari Lubis; Rafita Yuniarti
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 3 No. 1 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v3i1.2377

Abstract

Pati yaitu polisakarida yang termasuk karbohidrat yang terkandung dalam sel-sel tanaman. Pati mengandung amilosa dan amilopektin, dimana amilopektin dapat digunakan sebagai salah satu bahan dasar pembuatan film coated atau pelapis permukaan seperti tablet. Tujuan penelitian ini adalah untuk mengisolasi amilopektin dari pati jagung (Zea Mays L) berdasarkan karakteristiknya dan melalui uji iodin dan melihat dari gugus yang dihasilkan dengan menggunakan spektrofotometer IR. Berdasarkan dari hasil organoleptiknya yaitu berbentuk serbuk, berwarna putih dan tidak berbau sesuai syarat SNI 3451:2011, kadar abu total 0,9% masih memenuhi syarat MMI edisi VI, hasil uji iodin berwarna merah violet dan hasil analisis gugus menggunakan FTIR terdapat tiga gugus fungsi utama yang merupakan karakteristik dari amilopektin yaitu C-H, O-H dan C=O. Kesimpulannya serbuk yang dihasilkan merupakan serbuk amilopektin yang diisolasi dari pati jagung.
PERBANDINGAN DAYA HAMBAT TERHADAP PERTUMBUHAN BAKTERI Staphylococcus epidermidis ANTARA SERBUK SIMPLISISA KULIT DAUN & DAGING DAUN LIDAH BUAYA (Aloe vera(L.)Burm.f) Alma Dhita Shafira; Minda Sari Lubis; Gabena Indrayani Dalimunthe; D. Elysa Putri Mambang
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 3 No. 1 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v3i1.2379

Abstract

Bakteri Staphylococcus epidermidis merupakan satu dari tiga spesies bakteri gram positi Staphylococcus yang sering dijumpai. Staphylococcus epidermidis adalah flora normal pada kulit, saluran napas, dan saluran cerna manusia. Salah satu tanaman yang memiliki daya hambat terhadap pertumbuhan bakteri yaitu tanaman lidah buaya (Aloe vera L.)Burm.f Penelitian ini bertujuan untuk mengetahui perbandingan daya hambat antara serbuk simplisia kulit daun dan daging daun lidah buaya terhadap pertumbuhan bakteri Staphylococcus epidermidis. Metode penelitian ini adalah metode eksperimental, dengan melakukanerbandingan daya hambat terhadap pertumbuhan bakteri Staphylococcus epidermidis antara serbuk simplisia kulit daun dan daging daun lidah buaya (Aloe vera (L.)Burm.f.,. Data yang diperoleh dianalisis secara deskriptif kualitatif berupa diameter zona hambat. enelitian ini menggunakan rancangan penelitian deskriptif kualitatif yang bersifat memaparkan, menguraikan serta untuk mendapatkan gambaran daya hambat serbuk simplisia kulit daun dan daging daun lidah buaya terhadap bakteri Staphylococcus epidermidis. Hasil yang diperoleh menunjukkan bahwa serbuk simplisia kulit daun lidah buaya pada konsentrasi 6,25%, 12,5%, 25%, dan 50% termasuk kategori resistant (lemah). Begitu juga serbuk simplisia daging daun lidah buaya pada konsentrasi 6,25%, 12,5%, 25%, dan 50% termasuk kategori resistant (lemah) dan serbuk simplisia keseluruhan bagian daun lidah buaya pada konsentrasi 6,25%, 12,5%, 25% juga termasuk kategori resistant (lemah) sedangkan konsentrasi 50% termasuk kategori intermediate (sedang). Dapat disimpulkan bahwa serbuk simplisia kulit daun, daging daun serta kombinasi kulit dan daging daun lidah buaya memiliki daya hambat terhadap pertumbuhan bakteri Staphylococcus epidermidis dan hanya sampel kombinasi kulit dan daging daun lidah buaya dengan konsentrasi 50% yang memiliki daya hambat terbesar.
ISOLASI AMILOPEKTIN DARI PATI KULIT PISANG RAJA (Musa paradisiaca L) YANG BERPOTENSI SEBAGAI FILM COATED TABLET Adela Octi Dwiyani; Gabena Indrayani Dalimunthe; Minda Sari Lubis; Rafita Yuniarti
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 3 No. 1 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v3i1.2380

Abstract

Pati merupakan polisakarida yang jumlahnya melimpah pada sel-sel tanaman. Pati mengandung amilosa dan amilopektin, dimana amilopektin dapat digunakan sebagai salah satu bahan dasar pembuatan film coated atau pelapis permukaan seperti tablet. Tujuan penelitian ini adalah untuk mengisolasi amilopektin dari pati kulit pisang raja (Musa paradisiaca L.) berdasarkan karakteristiknya dan melalui uji iodin dan melihat dari gugus yang dihasilkan dengan menggunakan spektrofotometer IR. Berdasarkan dari hasil rendemen yang didapatkan berdasarkan perhitungan perbandingan antara berat pati dengan berat kulit pisang segar yaitu 3.33%. Setelah dilakukannya perhitungan persen rendemen isolasi amilopektin dengan cara membandingkan antara berat tepung amilopektin dengan berat pati, maka didapatkan hasil rendemen 72.67%. Hasil organoleptiknya yaitu berbentuk serbuk, berwarna coklat dan tidak berbau sesuai syarat SNI 3451:2011, kadar abu total 3% masih memenuhi syarat MMI edisi III dengan hasil dari ketiga pengulangan yaitu 1.4%, 1.2%, dan 1.3%, hasil uji iodin berwarna merah violet dan hasil analisis gugus menggunakan FTIR terdapat tiga gugus fungsi utama yang merupakan karakteristik dari amilopektin yaitu C-H, O-H dan C=O. Kesimpulannya serbuk yang dihasilkan merupakan serbuk amilopektin yang diisolasi dari pati kulit pisang raja.
Skrining fitokimia, formulasi dan uji mutu fisik nanoserum ekstrak bonggol nanas (Ananas comosus (L.) Merr) Rahma Maulidia Fitri; Minda Sari Lubis; Gabena Indrayani Dalimunthe; Rafita Yuniarti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.207

Abstract

Nanoserum is a slightly viscous transparent or semi-transparent preparation whose particle size is smaller than conventional serum. The purpose of this study was to find out that pineapple hump extract contains secondary metabolites, has physical quality and has a good level of stability in the form of nanoserum. The method used in this research is experimental, the sample used is pineapple hump. The data collected is in the form of quantitative and qualitative. The results showed that pineapple hump extract contains secondary metabolites of alkaloids, flavonoids, tannins, saponins, steroids, glycosides. Organoleptic test all formulas have a clear and transparent color. In the particle size and polydispersibility index tests (F0), (F1), (F2), (F3), all formulas showing particle size and polydispersibility index met the requirements of <1000 nm and polydispersibility index <0.5. Percent transmittance test (F0), (F1), (F2), (F3), all formulas have clear and transparent visual appearance according to the requirements of 90%-100%. There was no change in the stability level of nanoserum in the organoleptic test, the particle size test and the polydispersibility index (F0), (F1), (F2), (F3). There is a change in particle size and polydispersibility index afterCyling test, however, it is still categorized as good because it is in the range of quality requirements, namely <1000 nm and the polydispersibility index <0.5.
Sediaan krim ekstrak jeruk nipis (Citrus aurantifolia S.) Sebagai Obat luka sayat pada mencit jantan (Mus musculus) Madani Sirait; Gabena Indrayani Dalimunthe; Minda Sari Lubis; D. Elysa Putri Mambang
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.235

Abstract

Indonesia is a country that is rich in plant diversity. One of them is lime, which is used as a traditional wound medicine. Lime contains essential oil compounds, flavonoids, saponins, tannins, alkaloids, citric acid, amino acids, vitamin B1, and vitamin C. Based on previous research, flavonoids, tannins, and saponins can heal wounds. Making simplicia using an oven at 50oC  and characterizing simplicia Extraction using the maceration method with 96% ethanol is then concentrated using a rotary evaporator. Orientation on the preparation of the cream was carried out until a good cream texture was found, and a cream preparation test was carried out to comply with the requirements in the literature. The test animals used were 24 male mice, which were divided into six treatment groups. The first group was treated with betadine, the second group was treated with cream without extract, the third group was treated with 2 grams of extract cream, the fourth group was treated with 3 grams of extract cream, the fifth group was treated with 4 grams of extract cream, and the sixth group was untreated. Each group was given a 10-mm wound. Based on the treatment carried out for 14 days, the best formulation was a 4-gram lime extract cream, and the wound healed on day 9, which was the same as the comparison used, namely betadine.
Skrining Fitokimia, Formulasi, dan Karakteristik Fisik Sediaan Soothing Gel Daging Daun Lidah Buaya (Aloe vera (L.) Burm.f.) Rosalinda Mahdalena Sinaga; Minda Sari Lubis; Gabena Indrayani Dalimunthe; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.274

Abstract

The content of aloe vera (Aloe vera (L.) Burm.f.) can make the skin not dry quickly and feel moisturised. Soothing gel is a preparation that works effectively to restore skin moisture, provide comfort and a cooling effect on red and irritated skin so that the skin condition returns to normal and prevents skin dryness. The study aimed to determine the various secondary metabolites in aloe vera leaf flesh, to determine differences in concentrations of aloe vera leaf flesh in soothing gel preparations on the physical characteristics of the practices and to determine material changes before and after stability tests were carried out using the cycling test method. The research method was used experimental, with the independent variables varying the aloe vera leaf flesh concentration 0% (blank), 1%, 2%, and 3%, and the dependent variable secondary metabolites and physical characteristics. The sample preparation method is wet sorting, and other methods used are phytochemical screening, viscometry, and cycling tests. The results of the phytochemical screening showed that aloe vera leaf flesh contains secondary metabolites of flavonoids, glycosides, tannins, saponins, and steroids. The results of the soothing gel formulation with variations in the aloe vera leaf flesh concentration of 0%, 1%, 2%, and 3% showed differences in colour, distinctive aroma, consistency, spreadability, adhesion, pH, and viscosity that met the requirements. The stability test results using the cycling test method showed physical changes in consistency, spreadability, adhesion, pH, and viscosity. However, these changes still met the requirements for good gel preparation according to SNI 16-4399-1996.
Co-Authors Adani, Bazlina Adela Octi Dwiyani Adli Nuzula Rahmah Agustina, Meri Ahmad darwis Alma Dhita Shafira Anny Sartika Daulay Anugrah, Bayu Arianti, Sellin Arina Ashar, Diya Asparyzha, Rhyzha Aulia Fitri, Aulia Aulia, Meisyah Bambang Hermanto Basaniah Basaniah Chairina Milda Chandra, Putra Cindy Marlina Tambunan Claudy Friesta Melanie Cut Erika Maulydya D Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang Debi Meilani Dena, Mutia Dewa, Fasca Dikki Miswanda Dina Sri Novita Dina Veranika Dinda Sari Utami Dison Silalahi, Alistraja Emmy Wiriandini Fadhilah M, Ihsan Fadillah, Nike Fathur Rahman Febiyani, Rica Fithri Pulungan, Ainil Fitri Febriani Fitri, Raissa Ginting, Ovalina Sylvia Br. Girsang, Raflika Azwanda Gita Dwi Puspa Fadillah Hamda, Haikal Handayani, Riska Haris Munandar Nasution Hasibuan , Fika Miah Sasmitha Hendraputra, Hardy Handoko Heru Adha Prayogo Humairah, Dwina Angelina Husna, Miftahul husna, nadiatul Ilmi Widya Sari Isnaria, Vita Jurida, Wike Juwita, Sukma Karlina Butar Butar Kartika, Dinda Dwi Khairil Pahmi Khairunnisa , Ardina Kiki Rawitri Latifah Sahara Pulungan Lestari, Amanda Putri Lestari, Seri Lestari, Sri Indah Linda, Rosa Lisa Amalia Lubis, Minda Sari M. Arya Wiguna Madani Sirait maghfirah, Suci Mambang, D Elysa Putri Mambang, Elysa Putri Misna Rosalinda Hutabarat Muhammad Amin Nasution Muhammad Ricky Ramadhian Muhammad Tegar Tri Rizky Mutiara Rahmah Nasution, M. Pandapotan Nasution, Nur Sahadah Nasution, Shamila Sufi Aulia Nasution, Vevi Sarah Nia Novranda Pertiwi Nindya Indah Damayanti Ningtias, Anggitha Niswa, Khairun Novita Sari, Helsa Nur Asia, Nur Nur, Hijrotun Nuraisyah Nurfadilla, Kiki Nurliansyah, Nurliansyah Nurmala, Dewi Nurul Haliza Lubis Nurul Hidayah Nurul Salsa Abya Ritonga Olita, Apen Peri , Peri Peri, Peri Puteri, Cut Intan Annisa Rafita Yuliarti Rafita Yuniarti Rafita Yuniarti Rahma Dona Rahma Maulidia Fitri Rahmi , Ulfa Rambe, Robiatun Rambe, Sitiapsah Rangkuti, Cindy Rahayu Rawitri, Kiki Riani, Nur Aslin Ricky Andi Syahputra Ricky Andi Syahputra Ridwan Taher Lubis Ridwanto Ridwanto Rima Marwarni Rina Azhari Risnayanti Ritonga, Oktavia Riza Syafira Robiatun Rambe Rosalinda Mahdalena Sinaga Rosalinda Mahdalena Sinaga sahrianti, Hikmah Samosir, Anzly Hasian Samran, Samran Saragih, Aqilah Mutmainnah Sari Lubis , Minda Sari Lubis, Winda Sari, Syilvi Rinda Sartika Daulay, Anny Savika, Anggraini Selvicahyani, Selvicahyani Shinta Mida Ariani Harahap Sihotang, Laura Indah Restu Silvia Sinaga, Rosalinda Mahdalena Siregar, Hikmatussabaria Siti Anisa Siti Anisa Sitinjak, Iyustri Ririn Situmorang, Lusi Grasia Sri Mulia Ningsih Siregar Sri Wahyuni Sri Wahyuni Sulaiman Riadi Sulwiyatul K Sani Syahputri, Maulida Syarifah Aulia Syarifah Mauliza Tasya Ardana Ummu Safura Sirait Wardah Tulail Nadila Widya Sari Winda Aulia Yayuk Putri Rahayu Yayuk Putri Rahayu Yuli Apriani Br.Lubis Yuni Sartika Yuniarti , Rafita Yuniarti, Rafita Yuniarti, Rapita Zahara, Anisa Zahira Ahmad, Madani Ziza Putri Aisyia Fauzi Zulmai Rani