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Optimizing Monkeypox Detection Using Advanced Class Imbalance Handling Methods: Smote, Smote-Enn, Smote-Tomek, Borderline-Smote Rizki, Fahlul; Widowati, Widowati; Widodo, Catur Edi
Journal of Applied Data Sciences Vol 7, No 2: May 2026
Publisher : Bright Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47738/jads.v7i2.1286

Abstract

Monkeypox is a zoonotic viral disease with increasing global concern due to its rapid spread and potential public health impact. Accurate and timely detection is crucial, yet the development of machine learning-based detection systems is often challenged by class imbalance in clinical datasets, leading to biased predictions towards majority classes. This study systematically evaluates the effectiveness of various class imbalance handling techniques, including SMOTE, Borderline-SMOTE, SMOTE-ENN, and SMOTE-Tomek, on the performance of ensemble learning algorithms, specifically Random Forest and Gradient Boosting, for monkeypox detection. Using a dataset of 25,000 synthetic patient records with 11 clinical features, models were trained and validated through stratified 5-fold cross-validation. Performance metrics including accuracy, precision, recall, F1-score, and Area Under the Curve (AUC), along with ROC analysis, were employed to assess the impact of each augmentation method. Results indicate that hybrid methods, particularly SMOTE-ENN, significantly improve recall and F1-score, improving the detection of clinically important monkeypox-positive cases while maintaining adequate discriminative ability. Standard SMOTE and SMOTE-Tomek provide stable performance across metrics, whereas Borderline-SMOTE shows lower recall despite high precision. These findings highlight the importance of selecting appropriate class imbalance handling strategies tailored to the clinical objective, emphasizing sensitivity in detecting positive monkeypox cases. The study provides practical guidance for implementing reliable and robust machine learning models in early monkeypox detection, contributing to improved clinical decision-making and public health interventions.
Co-Authors Abbyasha, Raihan Bagas Agnes Quartina Pudjiastuti Agustino, Muchammad Alfiana, Shinta Nur Alighiri, Dante Ana Arifatus Sa'diyah Anti, Ajeng Rusti Aprianto, Desta Putra Apriyanti, Kristin Apriyanto, Bejo Ardiyanti, Oktavia Aris Sugiharto Artdhana, Bayu Asih, Dwi Putri Asnah Asnah Astutik, Endang Puji Atika Atika Ayudyana Suyudi, Godeliva Azis, Moh. Ivan Azizah, Shefia Nur Baharuddin, Moch. Ilham Bambang Sugiantoro Bhakti Wardoyo Putro, Die BIRU, SIRILUS MARIO Budiman, Husein Arief Cahya, Utik Tri Wulan Catur Edi Widodo David Kaluge Depi, Karisma Desy Rufaidah, Desy Die Bhakti Wardoyo Putro Dipo Aldila Eka Triyana Eko Rini Indrayatie Fadhlan, Rijaldi Fajar Nugraha Farida, Syarifah Ida Godeliva Ayudyana Suyudi Gunevo, Pilipus Haq, M. Nashirul Harahap, Adhina Rizkillah Hariadi Darmawan, Hariadi Heliany, Ina Hendro Hendro, Hendro Hidayati Karamina Husodo, Martanto Setyo I Made Indra I Made Indra Agastya Irliana Faiqotul Himmah Jaspis, Yakobus Jupriyati, Jupriyati Karlina, Dira Karsinah - Kartono , Khairani, Keysha Kusumaningtias, Berliana Gita Kusumo Nugraheni, Dinar Mutiara Listiyani, Laily Rochmawati Mahendra, Agus Margareta Rahayuningsih Nugroho Edi K Maria Krisnawati Maryana, Lilis Ma’mun, Saeul Meilia, Shinta Indah Mohamad Aldi Renaldi Muhamad Soleh Mukhlis Mukhlis Murti , Ghanesya Hari Nana Kariada Trimartuti Nana Supriyana Nariah, Nariah Nikken Prima Puspita Nikmatul Khoiriyah Nikmatul Khoiriyah Noorvy, Dian Norma, Chandra Nugroho, Fiska Maulidian Nurfida, Ulifah Nurhidayati Nurhidayati Nurmasitah, Sita Oktavia, Angeline Permatasari, Tiara Adinda Praharto, YB. Prajanto Wahyu Adi, Prajanto Wahyu Pratama, Muhammad Aldhi Primadona Puspita, Dila Puspita, Oktaviabi Windra Puspito, Agung Nugroho Putri, Ferentika Noftrianda Putri, Laila Listiani Rahmawati, Aisyah Putri Ratih, Inayah Swasti Ratna Herdiana Redemtus Heru Tjahjana Reku, Efraim Umbu Riadin, Diana Rina Fiati Rina Rachmawati Rizki, Fahlul Rizkuna, Risang Dakah Roudlotus Sholikhah Sadiyah, Ana Arifatus safiih, Abdul Rahman SALMI, IRMA NURUL Samsudi . Saputra, Rafael Leo Satriyo Adhy Sa’diyah, Ana Arifatus Selvy Nugraheny, Ria Senus, Teofano Anglaka Setianingrum, Winda Setiawan, Kevin Ishak Tri Sholikhah, Anggun Prawati Maratu Sholikhah, Roudlotus Sholikhah Sihotang, Muhenri Slamet Aji Pamungkas Sri Endah Wahyuningsih Subianto, Edwin Suhudi, Suhudi Sunyoto Sunyoto Suryoto Suryoto Sutrisno, Sutrisno Suwarti Suwarti Suyudi, Godeliva Ayudyana Titik Ekowati Triyana, Eka Utis Sutisna Utomo, Styo Budi Wandah Wibawanto Wardoyo Putro, Die Bhakti WATI, LIA Widya Hary Cahyati Wilujeng, Retno Windra Puspita, Oktaviani Wiranti Wiranti Y. A. Triana Ohoiwutun, Y. A. Triana Y.A. Triana Ohoiwutun, Y.A. Triana Y.D. Sumanto Yumna, Qonitah Yusuf, Ade