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All Journal e-GIGI Jurnal Kedokteran Brawijaya Indonesian Journal of Cancer Chemoprevention Jurnal Kesehatan Andalas JIMKesmas (Jurnal Ilmiah Mahasiswa Kesehatan Masyarakat) The Indonesian Biomedical Journal Sari Pediatri Paediatrica Indonesiana Jurnal Gizi Klinik Indonesia Jurnal Kesehatan Medika Saintika B-Dent, Jurnal Kedokteran Gigi Universitas Baiturrahmah Acta Biochimica Indonesiana Jurnal Hilirisasi IPTEKS (JHI) Buletin Ilmiah Nagari Membangun Oto Rhino Laryngologica Indonesiana Majalah Kedokteran Andalas Jurnal Biomedika dan Kesehatan Syntax Idea Jurnal Pengabdian kepada Masyarakat Nusantara Jurnal Ilmu Kesehatan Indonesia (JIKSI) Jurnal Riset Rumpun Ilmu Kedokteran (JURRIKE) Jurnal Otorinolaringologi Kepala dan Leher Indonesia (JOKLI) Vitalitas Medis : Jurnal Kesehatan Dan Kedokteran Jurnal Sains, Teknologi dan Kesehatan
Eti Yerizel
Fakultas Kedokteran Universitas Andalas
Aerospace Engineering Agriculture, Biological Sciences & Forestry Humanities Automotive Engineering Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Computer Science & IT Decision Sciences, Operations Research & Management Dentistry Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Materials Science & Nanotechnology Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Journal : The Indonesian Biomedical Journal

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Comparison of Transforming Growth Factor-Beta 1 Concentration in Preeclampsia and Normal Pregnancy Women Yusrawati Yusrawati; Dyka Aidina; Eti Yerizel
The Indonesian Biomedical Journal Vol 9, No 1 (2017)
Publisher : The Prodia Education and Research Institute (PERI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18585/inabj.v9i1.310

Abstract

BACKGROUND: According to the theory of endothelial dysfunction, the pathogenesis of preeclampsia is associated with the imbalance of angiogenic and anti-angiogenic factors. Transforming growth factor-beta 1 (TGF-β1) has also proposed as a proangiogenic factor that influences preeclampsia. This study was conducted to compare a mean difference of TGF-β1 between preeclampsia and normal pregnancy.METHODS: This study was an observational crosssectional study with 25 subjects of pregnant women with preeclampsia and 25 subjects of normotensive pregnant women. The study was conducted in Dr. Reksodiwiryo Hospital, Bhayangkara Hospital, and Dr. Rasidin Hospital in Padang, Indonesia from October 2015 to January 2016. For the determination of TGF-β1 concentration, peripheral Abstract venous blood samples were taken. The blood samples were analyzed by enzyme-linked immunosorbent assay (ELISA) in Biomedical Laboratory, Faculty of Medicine, Andalas University. The mean difference was statically analyzed by independent samples T-test.RESULTS: The mean difference of TGF-β1 was lower in preeclampsia group than normal pregnancy group (2.02±0.99 ng/mL vs. 3.24±2.67 ng/mL; p<0.05).CONCLUSION: The TGF-β1 concentration was lower in pregnant women with preeclampsia. Thus, it may have a role as a marker in preeclampsia.KEYWORDS: preeclampsia, normal pregnancy, transforming growth factor-beta1, TGF-β1
Co-Authors Ade Asyari Afriwardi Afriwardi Aga Pratama Ahmad Syukri Harahap Aisyah Elliyanti Al Hafiz Al Hafiz Al Ichram Novialdi, Rayhan Aljassri, Resti Karunia Amelin, Fitrisia Andani Eka Putra Angga Putra Perdana Anjelina Puspita Sari Ariani Zaltin Okvenda Arina Widya Murni Arni Amir Ashrifurrahman, Ashrifurrahman Asti Marian Sari Aumas Pabuti Bramadi Arya Caesar Rayhand Arrafif Nasution Cimi Ilmiawati, Cimi Daan Khambri Debby Apri Grecwin Deddy Saputra Desmawati Desmawati Dessy Arisanty Desy Arisanti Desy Arisanti Dezi Ilham Dia Rofinda, Zelly Dia Dian Pertiwi Dian Pertiwi Dina Arfiani Rusjdi Dyka Aidina Ebill Fuji Edison Effy Huriyati Efrida Efrida Ega Purnamasari Eka Agustia Rini Eka Agustria Rini Eliza Anas Elizabeth Bahar Elmatris Sy Endah Puji Septisetyani, Endah Puji Eva Chundrayetti Eva Decroli F, Annisa Maida Fadil Oenzil Fauziah, Dita Firdawati, Firdawati Fitri Zahara Fitriyana Fitriyana Gusti Revilla Hafni Bachtiar Hafni Bachtiar Hafni Bachtiar Hirowati Ali Hudila Rifa Karmia Husnil Kadri Irwan Ismawati Ismawati Janra, Muhammad Nazri Karmia, Hudila Rifa Karolin Trisnawelda Kastian, Ria Fajarwati Lili Irawati Maliza, Rita Masrul Masrul Syafri Meilisa Rahmawati Meiza Nerawati Mizwar Mizwar Muhamad Gerry Fadilla Muhammad Idris Nadhifah Salsabila Nadila Andam Astari Netti Meilani Simanjuntak Netti Suharti, Netti Niki Astria Nila Kasuma Nila Kusuma Nita Afriani Nofrita Nofrita Novialdi . Nurhajjah, Sitti Nursal Asbiran Okvenda, Ariani Zaltin Pratama Elisa, Tasya Putri Pratita Jati Permatasari Putra Santoso Putri, Athifa Alya Rahma Putri Idaman Rahmadian, Rizki Rahmatina B Herman Rahmatini . Rahmawati, Meilisa Rauza Sukma Rita Raveinal Rayhan Al Ichram Novialdi Reny Jayusfani Revivo Rinda Pratama Rizki Rahmadian Ronaldi Noor Rudy Afriant Sabar Hutabarat Saptino Miro Saptino Miro, Saptino Sari, Asti Marian Silvy Dioni Simanjuntak, Netti Meilani Sinurat, Arthauly Yopita Siti Nurhajjah Sukri Rahman Syahid MP, Miskah Indah Tiara Dwi Pratiwi Tofrizal Tofrizal, Alimuddin Utami, Refi Amalia Vella Paraditha Wilson Novarino Yanwirasti Yanwirasti Yaswir, Rita Yerizel, Almurdi Yerizel, Raveinal Yesi Mustika Sari Yulia Iriani, Yulia Yulistini, Yulistini Yusrawati Yusrawati Yusri Dianne Jurnalis Yustini Alioes Zelly Dia Rofinda Zulfadli Syahrul, Muhammad Zulkarnain Edward ZURAIDA ZURAIDA