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All Journal Journal Pharmaceutical Science and Application (JPSA) Jurnal Administrasi Kesehatan Indonesia Jurnal Farmasi Klinik Indonesia Mutiara Medika: Jurnal Kedokteran dan Kesehatan INDONESIAN JOURNAL OF PHARMACY Pharmascience JURNAL FARMASI DAN ILMU KEFARMASIAN INDONESIA Jurnal Surya Medika JURNAL MANAJEMEN DAN PELAYANAN FARMASI (Journal of Management and Pharmacy Practice) Majalah Farmaseutik Pharmasipha JSFK (Jurnal Sains Farmasi & Klinis) Jurnal Farmasi Indonesia Indonesian Journal of Global Health research Jurnal Farmasi Sains dan Praktis JURNAL FARMASI DAN KESEHATAN INDONESIA Academic Hospital Journal Indonesian Journal of Biomedicine and Clinical Sciences Indonesian Journal of Pharmacology and Therapy
Chairun Wiedyaningsih
Fakultas Farmasi Universitas Gadjah Mada
Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Dentistry Education Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Materials Science & Nanotechnology Medicine & Pharmacology Neuroscience Nursing Public Health Other

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The role of family caregivers in medication adherence of elderly in Asian setting: a scoping review Wiedyaningsih, Chairun; Widyakusuma, Niken Nur; Sri Suryawati
Indonesian Journal of Pharmacology and Therapy Vol 4 No 2 (2023)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.8379

Abstract

Family caregivers for elderly play a very important role in implementing drug adherence, especially in Asian countries. Various determinants of medication adherence included caregivers as family support. Although the relationship between family support is not always significant, understanding the factors of family caregivers on medication adherence is important, especially when improving adherence in Asian countries. The following scoping review was conducted to provide an overview of caregivers, and its relationship to medication adherence in Asian settings. PRISMA-ScR guideline and checklist was used for the search process and to guide reporting. Review selection and characterization were performed by reviewers independently. In total, 22 papers were included in the review, published from 2011 to 2021. The studies varied in terms of purpose, methodology, and detail of reporting. Family caregiver is an important determinant of medication adherence, especially for areas where extended family culture is still strong, such as in Asia. Understanding the local culture, aspects of family burden and economic, as well as the role of the health profession, especially pharmacists in health services are needed to improve adherence. Therefore, further research with quality methods is needed.
The effect of zinc and probiotics supplements in children under 5 years old with diarrhea Zhaqila, Qhifani; Ruspandi, Sugeng; Wiedyaningsih, Chairun
Indonesian Journal of Pharmacology and Therapy Vol 5 No 2 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.10289

Abstract

The 2020 Indonesian Health Profile states that diarrhea is an endemic disease that has the potential to cause extraordinary events. Diarrhea is still one of the contributors to death in Indonesia, especially in children under 5 years old. This study aimed to evaluate the use of zinc and probiotic supplementation on the length of stay (LoS) of patients under 5 years old with diarrhea. It was an observational study using medical records of patients under 5 years old with diarrhea at the Academic Hospital, UGM Yogyakarta in the period of 2021 to 2022. Patient characteristics, including use and medications such as zinc supplementation and probiotics, as well as clinical outcomes including LoS were obtained from 100 medical records. Data were analyzed using chi square from Microsoft Excel 365 & Statistical Program for Social Science (SPSS) with a 95% confidence level (p<0.05). The majority of patients were male (61%) with age range 12-23 mo (47%), 3-4 times frequency of diarrhea (69%), dehydration mild-moderate (89%), and acute diarrhea (96%). The treatment of diarrhea was antidiarrheal (44.81%), fluid rehydration (32.55%), and antibiotics (22.64%). Most patients left the hospital in an improved condition and were allowed to go home (92%). There is a significant relationship between the use of zinc, probiotics, and a combination of zinc and probiotics on LoS.
The use of antihypertension in hypertension patients with chronic kidney failure at the Universitas Gadjah Mada (UGM) Academic Hospital, Yogyakarta Wijaya, Syifa Indi; Ryshang Bathari, Anggraini Citra; Wiedyaningsih, Chairun
Indonesian Journal of Pharmacology and Therapy Vol 5 No 1 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.10453

Abstract

According to the 2018 Indonesian Basic Health Research data, the prevalence of hypertension in the Yogyakarta Special Region (11.0%) is higher than the national average of 8.8%. Hypertension with chronic kidney failure is currently a prevalent and increasing issue. This study aimed to investigate the pattern and rationality of antihypertensive use in hypertension patients with chronic kidney failure (CKF) participating in the National Health Insurance (Jaminan Kesehatan Nasional/JKN) program at Universitas Gadjah Mada (UGM) Academic Hospital period of 2020 to 2022. The study was conducted using quantitative descriptive non-experimental methods. Data collection was carried out retrospectively through medical records of patients diagnosed with hypertension with CKF (ICD I12.0). Samples were selected using purposive techniques and analyzed by comparing the suitability of drug selection with standard hypertension therapy with CKF based on JNC 8 and NKF-K/DOQI, including the rationality of their use. A total of 68 patients over the age of 18 were used as samples. The The majority of drug groupsresults showed that a combination of 2 drugs is more dominant (52.9%) compared to monotherapy (29.4%) and a combination of 3 drugs (17.6%). The majority of drug groups used were angiotensin receptor blockers (ARBs), especially candesartan (45%). ARB and calcium channel blockers (CCB), especially candesartan+amlodipin (50%), and ARB +CCB+diuretic, especially andesartan +amlodipine + furosemide (33%).. The rationality of drug use showed that 66.2% in the right indications, 89.7% the right drugs, 100% in the right patients and 85% the right doses. Therefore, health workers still need to make efforts to encourage rational drug use.
Comparison ondansetron and domperidon as antiemetic for gastroenteritis in children: a review Siregar, Mardiana; Wiedyaningsih, Chairun; Mutiara, Rina
Indonesian Journal of Pharmacology and Therapy Vol 5 No 2 (2024)
Publisher : Faculty of Medicine, Public Health, and Nursing Universitas Gadjah Mada and Indonesian Pharmacologist Association or Ikatan Farmakologi Indonesia (IKAFARI)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/ijpther.11716

Abstract

Gastroenteritis (GE) is the leading cause of vomiting in children. It is the main reason children admitted into emergency departments (EDs). Vomiting can cause fluid loss therefore oral rehydration solution (ORT) is recommended as supportive care for mild to moderate dehydration. Antiemetic therapy for GE is not fully recommended by any management guidelines. However, in some studies, antiemetics including ondansetron and domperidone are used in vomiting-related GE. This review aimed to compare ondansetron and domperidone for the treatment of GE in children. The article search was performed to identify relevant publications using PubMed database PubMed. PRISMA flow diagram was used as protocol during the article screening process. Eight
Hubungan Dukungan Sosial dengan Kepatuhan Pengobatan Antiretroviral (ARV) pada Pasien HIV-AIDS di Kabupaten Sleman Syam AP, Andi Riska; Widayati, Anna Wahyuni; Wiedyaningsih, Chairun
Majalah Farmaseutik Vol 21, No 4 (2025): in press
Publisher : Faculty of Pharmacy, Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/farmaseutik.v21i4.94695

Abstract

Human Immunodeficiency Virus (HIV)/Acquired Immunodeficiency Syndromes (AIDS) merupakan masalah kesehatan dunia. World Health Organization (WHO) sebagai sektor kesehatan global telah menetapkan tujuan untuk mengurangi infeksi HIV tahun 2022-2030. Indonesia sendiri berupaya untuk mencapai Ending AIDS pada tahun 2030 sebagai bentuk komitmen bersama negara-negara lain di dunia. Ada beberapa kendala utama dalam meningkatkan kepatuhan pengobatan antiretroviral (ARV). Salah satunya faktor dukungan sosial. Penelitian ini bertujuan untuk mengidentifikasi hubungan antara dukungan sosial dengan kepatuhan pegobatan Antiretroviral (ARV) pada pasien HIV-AIDS. Jenis penelitian ini merupakan analitik observasional dengan desain studi cross sectional. Teknik pengumpulan sampel secara non probability sampling menggunakan metode convenience sampling dengan jumlah sampel 86 responden. Analisis data menggunakan perangkat lunak SPSS. Hasil penelitian menunjukkan dukungan sosial secara kuantitatif diperoleh 48,8% responden mendapat dukungan sosial tinggi, dan 51,2% mendapat dukungan sosial rendah, sedangkan dukungan sosial secara kualitatif diperoleh 64% responden merasa puas dan 36% merasa tidak puas. Kepatuhan pengobatan diperoleh 46,5% responden memiliki kepatuhan minum obat yang tinggi, dan 53,5% responden memiliki kepatuhan minum obat yang rendah. Jadi, tidak ada hubungan yang signifikan antara dukungan sosial secara kuantitatif dan kualitatif terhadap kepatuhan pengobatan Antiretroviral (ARV) pada pasien HIV-AIDS di Kabupaten Sleman.
Co-Authors A.A. Ketut Agung Cahyawan W Abdillah Mursyid Akuba, Jusnita Amna, Shily Rahmatika Anna Wahyuni Widayanti Ardiningtyas, Bondan Ardiyatul I. Kelana Ari Dwidayati As'hari, Yanuar Azni, Meicella Bai Athur Ridwan Bella Anggelina Dewa Ayu Putu Satrya Dewi Dewi, Mahmud Carica Ekasari, Marlita Putri Endang Yuniarti Fadilla, Andi Fakhriya, Dina Faluti, Dimas Rizki Ferina Septiani Damanik Fita Rahmawati Fita Rahmawati Ginanti Putri, Ni Putu Vyra Gunawan Pamudji Widodo Haris, Restu Nur Hasanah Harnita Harnita Hasina, Raisya Heni Lutfiyati Heni Lutfiyati, Heni I Dewa Putu Pramantara Indriastuti Cahyaningsih, Indriastuti Iwan Yuwindry Khrisna Heryanti Febti Kurniasar Kiki Yuli Handayani Kristanti, Nugraheni Dwiari Kukihi, Farha Elein Kurniawati, Fivy Lubis, Muammar Mahdiyani, Ulfah Malina, Rachma Marhenta, Yogi Bhakti Meicella Azni Melia Eka Rosita Muh Irham Bakhtiar Mulyagustina Mulyagustina Mulyagustina, Mulyagustina Mursyid, Abdillah Mursyida Ulfa Nanang Munif Yasin Nanang Munif Yasin Nanang Munif Yasin Nananng Munif Yasin Nia Primayani Niken Nur Widyakusuma Nita Trinovitasari Nugraheni Dwiari Kristanti Nur Aini Budiyanti Nur Hamida Nurul Mardiati Nurul Mardiati Nurul Mardiati Oetari . Pramuji Eko Wardani Pratama, I Dewa Putu Probosuseno Probosuseno Probosuseno Probosuseno, Probosuseno Putra, Juniawan Akbar Karisma Rachma Malina Rahmadani . Raisya Hasina Renni Simorangkir Restu Nur Hasanah Haris Ria Widyaswari Rina Mutiara Rina Mutiara, Rina Ruspandi, Sugeng Ryshang Bathari, Anggraini Citra Sampurno Sampurno Sampurno Sampurno Sampurno Sampurno Saskiya, Pingki Arum Satibi Satibi Satibi Satibi Satibi Satibi Setiabudi, I Dewa Putu Pramantara Simanullang, Raymon Siregar, Mardiana Sri Suryawati Sumarni Sumarni Sumarni Sumarni Susi Ari Kristina Susi Ari Kristina Susi Ari Kristina Susi Ari Kristina Susi Ari Kristina Susi Ari Kristina Susi Ari Kristina Syam AP, Andi Riska Taufiqurohman Titami, Arina Tri Murti Andayani Tri Murti Andayani Ulfah Mahdiyani Wa Ode Masrida Wahidah, Pujiastuti Wahyudi, Aiffian Farhan Wanggol, Agata Christi Febriani Warastuti . Widayanti, MPH., Apt., Ph.D., Anna Wahyuni Widayati, Anna Wahyuni Widyasari, Leiren Garda Wijaya, Syifa Indi Yatminto, Eko Yogi Bhakti Marhenta Yulia Citra Yuwindry, Iwan Zhaqila, Qhifani