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All Journal Journal of Marine Research INDONESIAN JOURNAL OF PHARMACY Jurnal Kimia Riset Jurnal Farmasi Sains dan Komunitas Jurnal Surya Medika Adi Widya : Jurnal Pengabdian Masyarakat Majalah Farmaseutik JPSCR : Journal of Pharmaceutical Science and Clinical Research Jurnal Farmasi Indonesia JFIOnline Jurnal Mandala Pharmacon Indonesia Cendekia Journal of Pharmacy Science Midwifery Budimas : Jurnal Pengabdian Masyarakat Avicenna : Journal of Health Research Jurnal Farmasi Jurnal Farmasi dan Sains Indonesia (JFSI) Journal of Fundamental and Applied Pharmaceutical Science Jurnal Pengabdian kepada Masyarakat Open Access Indonesian Journal of Medical Reviews Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi dan Kesehatan East Asian Journal of Multidisciplinary Research (EAJMR) Medical Sains : Jurnal Ilmiah Kefarmasian Formosa Journal of Multidisciplinary Research (FJMR) Jurnal Farmasi Sains dan Praktis Journal of Halal Science and Research Riset Informasi Kesehatan Journal of Health Management and Pharmacy Exploration (JOHMPE) Parapemikir Jurnal Ilmiah Farmasi Borneo Journal of Pharmacy Medical Sains : Jurnal Ilmiah Kefarmasian
Ilham Kuncahyo, Ilham
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Journal : Journal of Halal Science and Research

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Optimization of naringenin sunscreen cream formula using the simplex lattice design method Kartikasari, Ayu Lifia Nur; Wibowo, Anisa Devi Kharisma; Kuncahyo, Ilham
Journal of Halal Science and Research Vol. 4 No. 2 (2023): September
Publisher : Universitas Ahmad Dahlan

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.12928/jhsr.v4i2.7172

Abstract

Naringenin is a pure isolate belonging to a group of flavonoid compounds with pharmacological effects such as anti-inflammatory, anticancer, antiatherogenic, antifibrogenic, and antioxidant properties. The purpose of this study was to determine the effect of variations in the combination of emulator tween 80 and span 80 on physical quality and stability in naringenin sunscreen preparations, obtain the optimum formula composition from emulsifying agents, and activity of naringenin sunscreen cream preparations in terms of their SPF values. The study used Design Expert 7.1.5 software to design the simplex lattice design method. Each formula was tested for the physical properties of the cream to determine dispersal adhesion for 4 weeks. Naringenin sunscreen cream with a combination of emulsifier tween 80 and span 80 in various concentrations gives a significant difference in the physical quality consisting of the parameters of spreadability, adhesion, and viscosity. The optimum formula for naringenin sunscreen cream obtained the proportion of 9% Tween 80 and 5% span 80. Keywords: Naringenin, Simplex Lattice Design, SPF, Sunscreen.
Co-Authors Adam Ferdian Sigit Pratama Afif Afghohani, Afif Alfiana, Ina Ana Indrayati Ana Indriyati Anisa Devi Kharisma Wibowo Argoto Mahayana Ayuk Armadani , Valentina Bimo Putranto Candra, Dhimas Tiya Chaesti Setyo Hastuti Chatarina Umbul Wahyuni Dewi, Fitri Jaya Santi Utami Dian Marlina Dian Puspitasari Efrilia, Erin ELISABETH APRILIA Endang Diyah Ikasari Endang Dyah Ikasari Ghani Nurfiana Fadma Sari Gunawan, Lucia Sincu Hafizah, Dila Auli Hutami, Shabrina Nindya Ibnu Pratikto Ismi Rahmawati Iswandi Iswandi Kartikasari, Ayu Lifia Nur Kiki Puspitasary Kusumawati, Mulyaningtyas Ayu M Muchalal M. Andi Chandra M. Andi Chandra M. Henityo Agung As'adi Mahardira Dewantara Mahayana, Argoto Mamik Ponco Rahayu Mardiyono Mardiyono, . Mointi, Sella Septiyani Muhammad Dzakwan Muhammad Dzakwan Nicolay Wening Audrey Noval Noval Nugroho, Muhammad Agung Nur Hidayati Nur Hidayati Nuraini Harmastuti Octavia Krisma O Opstaria saptarini Prasasti, Anin Pudiastuti RSP Putri, Hana Maylinda Putri, Sukma Oktafiani Rakhmi Hidayati Reslely Harjanti Resmi, Juniar Kalpika Rini Prastiwi Rizqi Fitria Yanuar Roosma Hatmayana Rudhi Pribadi Saifullah, T.N Sari, Putri Rovita Septiawan Adi Nugroho Sesilia Putri Nandita Setyaningrum, Dewi Anggraheni setyawan, Ferdinta D Siti Aisiyah Siti Aisiyah Soebiyanto Soebiyanto, Soebiyanto Sugiyarmasto Sugiyarmasto, Sugiyarmasto Suhartinah Suhartinah, Suhartinah Sukarno Sumardiyono Sumardiyono Sumardiyono Sunardi Sunardi Sunardi Supriyadi Supriyadi Supriyadi Supriyadi Syafira Nabillah Syaiful Choiri T. N. Saifullah Sulaiman T.N. Saifullah Sulaiman T.N. Saifullah Sulaiman Taena, Adriani Teuku Nanda Saifullah Sulaiman Titik Sunarni Titik Sunarni TN Saifullah Sulaiman, TN Saifullah Turdiyanto, Totok Valentina Ayuk Armadani Vivin Nopiyanti Waluyo Budi Atmoko, Waluyo Budi Wijayanti, Ifa Rizki Wiwin Herdwiani Wulandari, RR Sri Yudanti, Gendis Purno Yudi Rinanto Yuliana, Sinta Zahra, Iklila