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All Journal Indonesian Journal of Pharmaceutical Science and Technology Jurnal Ilmu Kefarmasian Indonesia Pharmacoscript Science Midwifery Warta Pengabdian Andalas: Jurnal Ilmiah Pengembangan Dan Penerapan Ipteks Jurnal Abdimas Kartika Wijayakusuma Medical Sains : Jurnal Ilmiah Kefarmasian Public Health and Safety International Journal (PHASIJ) Sciences of Pharmacy Jurnal Farmasi Indonesia Jurnal An-Najat: Jurnal Ilmu Farmasi dan Kesehatan Ardhi: Jurnal Pengabdian dalam Negri Jurnal Kesehatan Bakti Tunas Husada Obat: Jurnal Riset Ilmu Farmasi dan Kesehatan Medical Sains : Jurnal Ilmiah Kefarmasian Ekspresi: Publikasi Kegiatan Pengabdian Indonesia International Journal of Health and Medicine Jurnal Farmasi Galenika Indonesian Journal of Jamu Sasambo: Jurnal Abdimas (Journal of Community Service)
Jajang Japar Sodik
Faculty Of Pharmacy, Universitas Bhakti Kencana
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Chemistry Computer Science & IT Dentistry Education Engineering Health Professions Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health Social Sciences Veterinary Other

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Bersama Desa Mangunarga: Membangun Perilaku Hidup Bersih dan Sehat untuk Kehidupan Sejahtera Mamay Maulana Sobandi; Yakobus Lau De Yung Sinaga; Roganda Situmorang; Isviyanti Isviyanti; Jajang Japar Sodik
Ekspresi : Publikasi Kegiatan Pengabdian Indonesia Vol. 1 No. 3 (2024): Publikasi Kegiatan Pengabdian Indonesia
Publisher : Asosiasi Seni Desain dan Komunikasi Visual Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62383/ekspresi.v1i3.213

Abstract

Waste management remains a major challenge in Indonesia, particularly concerning marine plastic waste and the increase in hazardous waste (B3). The lack of understanding and limited facilities such as TPS-3R and waste banks further exacerbate the situation. In response, we conducted a community service program in Mangunarga Village, Sumedang, West Java, aimed at raising awareness and improving waste management practices. This program included educational workshops and equipping waste processing facilities. The results showed a significant increase in community understanding and behavior related to waste management, with awareness rising from 16.5% to 97.2%, and proper waste sorting practices increasing from 8.2% to 96.3%. The success of this program underscores the importance of community-based approaches and supportive infrastructure in addressing environmental challenges at the local level.
UJI IN-SILICO SENYAWA TURUNAN KURKUMINOID SEBAGAI INHIBITOR BRUTON TYROSINE KINASE PADA LEUKIMIA LIMFOSITIK KRONIS Mulki Irpani, Abdul; Ilham Bintang, Muhamad; Putriyanti, Al-fira; Adinda, Deistha; Japar Sodik, Jajang
Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu-ilmu Keperawatan, Analis Kesehatan dan Farmasi Vol. 25 No. 1 (2025): Jurnal Kesehatan Bakti Tunas Husada Volume 25 Nomor 1 Tahun 2025
Publisher : LPPM Universitas Bakti Tunas Husada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36465/jkbth.v25i1.1496

Abstract

Leukemia is a blood cancer that occurs due to abnormal blood cell growth, especially white blood cells in the bone marrow. Research shows that curcumin is proven to be effective in inhibiting the activity of the NF-κB transcription factor which is often involved in the proliferation of cancer cells. This study aims to determine the potential of natural curcuminoid compounds against specific blood cancers, namely chronic lymphocytic leukemia. Through in-silico testing of curcuminoid derivative compounds against the Bruton Tyrosine Kinase protein target which plays a role in the pathophysiological process of chronic lymphocytic leukemia. The results of docking the test ligand molecule on the Tyrosine-protein kinase BTK enzyme, the native ligand has the lowest binding energy value (ΔG) of -12.04 kcal/mol with an inhibition constant (KI) of 1.49 nM. As a comparison drug, imatinib showed ΔG -11.05 kcal/mol with a KI of 7.88 nM. Test ligands s02, s05, and s08. Ligand s02 showed a ΔG of -9.43 kcal/mol with a KI of 123.19 nM, while s05 had a ΔG of -9.09 kcal/mol with a KI of 218.10 nM. Meanwhile, s08 recorded a ΔG of -9.33 kcal/mol and a KI of 143.83 nM. Although the affinity values of the three test ligands were lower than those of the natural ligands, they had the potential to bind to the target enzyme. Based on the interaction analysis, it was seen that s05 had the potential for competitive inhibition, while s02 and s08 showed lower interaction stability compared to imatinib. This indicates that s05 has the greatest potential as a potential inhibitor of the BTK enzyme compared to other test ligands.
Edukasi Kesehatan dan Pemanfaatan Herbal untuk Pencegahan dan Pengelolaan Hipertensi di Kabupaten Bandung Patonah Patonah; Aris Suhardiman; Lia Marliani; Purwaniati Purwaniati; Mamay M Sobandi; Jajang Japar Sodik
Sasambo: Jurnal Abdimas (Journal of Community Service) Vol. 6 No. 4 (2024): November
Publisher : Lembaga Penelitian dan Pemberdayaan Masyarakat (LITPAM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/sasambo.v6i4.2128

Abstract

Program pengabdian masyarakat ini berfokus pada edukasi kesehatan dan pemanfaatan herbal untuk pencegahan dan pengelolaan hipertensi di Kabupaten Bandung. Program ini dirancang untuk mengatasi tingginya prevalensi hipertensi melalui pendekatan promotif dan preventif. Kegiatan edukasi meliputi seminar kesehatan interaktif, demonstrasi praktis penggunaan herbal, serta skrining kesehatan yang mencakup pengukuran tekanan darah, glukosa, kolesterol, dan asam urat. Hasilnya menunjukkan peningkatan signifikan dalam pengetahuan masyarakat, di mana persentase peserta dengan pemahaman memadai tentang hipertensi meningkat dari 19% menjadi 72%. Selain itu, peserta mulai menerapkan perilaku hidup sehat, seperti mengurangi konsumsi garam dan meningkatkan aktivitas fisik. Pengenalan herbal seperti jahe, kunyit, dan seledri memberikan alternatif strategi pengendalian tekanan darah yang mengintegrasikan kearifan lokal dengan ilmu pengetahuan modern. Inisiatif ini menunjukkan efektivitas intervensi berbasis komunitas secara holistik dalam meningkatkan hasil kesehatan masyarakat dan pentingnya program edukasi kesehatan yang berkelanjutan. Health Education and Herbal Utilization for Hypertension Prevention and Management in Bandung Regency This community service program focused on health education and herbal utilization for the prevention and management of hypertension in Bandung Regency. The program was designed to address the high prevalence of hypertension through promotive and preventive approaches. Activities included interactive health seminars, practical demonstrations on herbal utilization, and health screenings for blood pressure, glucose, cholesterol, and uric acid levels. The results showed a significant improvement in community knowledge, with the percentage of participants with adequate understanding of hypertension increasing from 19% to 72%. Additionally, participants adopted healthier behaviors, such as reducing salt intake and increasing physical activity. The introduction of herbal remedies, including ginger, turmeric, and celery, offered alternative strategies for blood pressure control, integrating local wisdom with modern science. This initiative demonstrated the effectiveness of holistic community-based interventions in improving public health outcomes and underscored the importance of sustainable health education programs.
Hipertensi dalam Kehamilan dan Risiko Stunting Intervensi Sosialisasi Kesehatan untuk Mencegah Stunting di Masa Depan Muhamad Reza Pahlevi; Dadang Juanda; Nita Selifiana; Ika Kurnia Sukmawati; Widhya Aligita; Deni Iskandar; Jajang Japar Sodik
Sasambo: Jurnal Abdimas (Journal of Community Service) Vol. 6 No. 4 (2024): November
Publisher : Lembaga Penelitian dan Pemberdayaan Masyarakat (LITPAM)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36312/sasambo.v6i4.2231

Abstract

Pengabdian masyarakat ini bertujuan untuk meningkatkan kesadaran mengenai hubungan antara hipertensi pada kehamilan dan risiko stunting melalui intervensi edukasi kesehatan. Dengan pendekatan kuasi-eksperimen, program ini melibatkan evaluasi pre-test dan post-test dengan 30 wanita dewasa di Desa Serang Mekar, Kecamatan Ciparay, Kabupaten Bandung. Partisipan dipilih secara purposif berdasarkan persetujuan dan kondisi kesehatan. Hasil menunjukkan peningkatan signifikan dalam pengetahuan, dengan pemahaman mengenai kaitan hipertensi dan stunting naik dari 43,3% pada pre-test menjadi 100% pada post-test. Pengukuran tekanan darah sebelum dan sesudah sesi edukasi juga menunjukkan perbaikan, yang mengindikasikan dampak positif program edukasi terhadap kesadaran dan praktik kesehatan. Pengabdian ini merekomendasikan edukasi kesehatan berkelanjutan yang fokus pada pengelolaan hipertensi selama kehamilan, terutama di daerah pedesaan. Inisiatif berbasis komunitas dengan melibatkan kader kesehatan lokal dapat meningkatkan keberlanjutan program dan membantu menurunkan prevalensi stunting di Indonesia. Hypertension in Pregnancy and the Risk of Stunting: Health Education Intervention to Prevent Future Stunting This community service aimed to raise awareness about the link between hypertension in pregnancy and the risk of stunting through health education interventions. Using a quasi-experimental approach, the program involved pre-test and post-test evaluations with 30 adult women in Desa Serang Mekar, Kecamatan Ciparay, Kabupaten Bandung. Participants were purposively selected based on consent and health status.Results showed a significant increase in participants’ knowledge, with recognition of the link between hypertension and stunting rising from 43.3% in the pre-test to 100% in the post-test. Blood pressure measurements before and after the sessions also improved, indicating a positive impact of the education program on health awareness and practices. This community service recommends ongoing health education focused on managing hypertension during pregnancy, particularly in rural areas. Community-based initiatives involving local health cadres can enhance the program’s sustainability and help reduce stunting prevalence in Indonesia
Utilization of TOGA to Reduce the Risk of Hypertension in Cibiru Wetan Village Jajang Japar Sodik; Fenti Fatmawati; Mia Nisrina Anbar Fatin; Wempi Budiana
Warta Pengabdian Andalas Vol 32 No 1 (2025)
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat (LPPM) Universitas Andalas

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/jwa.32.1.55-60.2025

Abstract

Community service activities in Cibiru Wetan Village, Bandung Regency have been carried out by lecturers and students of the Faculty of Pharmacy, Bhakti Kencana University (BKU) with partners, namely PKK Cibiru Wetan and Cibiru Wetan Health Center. Activities carried out in November include health screening (blood pressure, blood sugar, uric acid and total cholesterol checks), education on hypertension and the benefits of TOGA, training in processing medicinal plants such as ginger, Kaempferia galanga, and Curcuma into ready-to-consume herbal products, distribution of booklets on practical guidelines for the use of TOGA. This activity involves BKU lecturers from various expertise groups such as Pharmacology & Clinical Pharmacy; Pharmacy and Pharmaceutical Technology; General Pharmacy and Pharmacists; Pharmaceutical Biology.
Evaluation of antipsychotic utilization among outpatient schizoprenia patients at the mental health facility in West Java Sutrisno, Entris; Selifiana, Nita; Sodik, Jajang Japar; Fajarrini, Uvika Nurul
JURNAL ILMU KEFARMASIAN INDONESIA Vol 23 No 1 (2025): JIFI
Publisher : Faculty of Pharmacy, Universitas Pancasila

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35814/jifi.v23i1.1632

Abstract

Rational use of drugs aims to give therapy according to patient’s clinical needs. Based on Ni komang's research (2021) there are still inaccuracies in the use of antipsychotic drugs. The purpose of this study was to determine the evaluation of the use of Antipsychotics based on the parameters of right indications, drugs, dosage, and frequency in outpatient schizophrenia patients at the West Java Provincial Mental Hospital. The study used a method with descriptive presentation of data and retrospective data collection. Data obtained period October-December 2022 from 130 patients, this study evaluated the use of Antipsychotics with the parameters of right indications, drugs, dosage, and frequency then the data will be analyzed based on the criteria for drug use from Pharmacotherapy A Pathophysiologic Approach 11th and PIONAS. The results of the study on the use of Antipsychotics in schizophrenic patients at the Java Provincial Mental Hospital based on Pharmacotherapy A Pathophysiologic Approach 11th and PIONAS obtained the right indications as much as (100%), the right drugs (100%), the right dose (98%), and the right frequency (98%).
Evaluation of Antibiotic Use in Inpatient and Outpatient Diabetic Ulcer Patients at a Government Hospital in Bandung Sutrisno, Entris; Anggriani, Ani; Sodik, Jajang Japar
Sciences of Pharmacy Volume 4 Issue 2
Publisher : ETFLIN Publishing House

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58920/sciphar0402318

Abstract

Diabetic foot ulcers are caused by neuropathy and/or peripheral arterial disease in patients with type 2 diabetes mellitus. These infections are commonly treated with empirical antibiotics. However, excessive or inappropriate antibiotic use may lead to resistance and poor treatment outcomes. This study aimed to evaluate antibiotic prescribing patterns, rationality, and potential drug interactions in diabetic ulcer patients at a government hospital in Bandung from January to December 2023. A retrospective observational design was used to analyze medical records of 63 patients. The most frequently used single antibiotics were ceftriaxone (51%), cefixime (20%), and ceftizoxime (17%), while the most common combination therapy was ceftizoxime + metronidazole (24%). Evaluation of antibiotic rationality showed 100% appropriate indication, 90.48% appropriate drug selection, and 98.41% appropriate dosage. Despite this, 33.33% of prescriptions had potential drug interactions with commonly co-prescribed medications. These findings indicate generally rational antibiotic use with areas for improvement in drug selection and interaction management. The study highlights the importance of continuous monitoring and rational prescribing to prevent antimicrobial resistance and ensure patient safety.
Hubungan Tingkat Kepatuhan Pengobatan Antidiabetes Terhadap Kualitas Hidup Pasien Diabetes Melitus Tipe 2 Rawat Jalan di Salah Satu Rumah Sakit di Kabupaten Bandung Priyadi, Akhmad; Japar Sodik, Jajang; Maulana Sobandi, Mamay; Siti Nurfitria, Rizki; Sabarudin, Cecep; Riyadi, Imam
Public Health and Safety International Journal Vol. 5 No. 01 (2025): Public Health and Safety International Journal (PHASIJ)
Publisher : YCMM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55642/phasij.v5i01.988

Abstract

Diabetes Melitus tipe 2 merupakan penyakit metabolisme kronik, yang tidak dapat disembuhkan namun hanya dapat dikontrol dengan terapi farmakologi dan non farmakologi, Jika manajemen kesehatan tidak dilakukan dengan baik maka dapat menyebabkan komplikasi dan mempengaruhi kualitas hidup penderita. Tujuan penelitian ini untuk mengetahui hubungan kepatuhan minum obat dengan kualitas hidup pasien diabetes melitus tipe 2 di salah satu Rumah Sakit di Kabupaten Bandung. Penelitian ini menggunakan metode observasional analitik dengan desain cross sectional yang diambil secara Non-probability sampling. Pengambilan data dilakukan pada bulan Maret – April 2024 terhadap 95 responden diabetes melitus tipe 2. menggunakan kuesioner MMAS-8 (Eight-item Morisky Medication Adherence Scale) dan EQ-5D-5L (Euro-Quality of Life-5 Dimension-5 level). Hasil menunjukkan pasien diabetes melitus tipe 2 memiliki tingkat kepatuhan minum obat sedang (44,2%) dan kualitas hidup tinggi (62,1%). Terdapat hubungan signifikan yang kuat dan searah antara kepatuhan minum obat antidiabetes dan kualitas hidup pasien Diabetes melitus tipe 2 rawat jalan disalah satu Rumah Sakit di Kabupaten Bandung dengan nilai p 0,000 (p < 0,05) dengan tingkatan koefisien korelasi cukup kuat.
Analisis Faktor yang Mempengaruhi Kualitas Hidup pada Pasien Penderita Kanker Payudara di Rumah Sakit Priyadi, Akhmad; Japar Sodik, Jajang; Maulana Sobandi, Mamay; Saidah Mutmainah, Siti; Sabarudin, Cecep; Aqila Fadia, Andira
Public Health and Safety International Journal Vol. 5 No. 01 (2025): Public Health and Safety International Journal (PHASIJ)
Publisher : YCMM

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.55642/phasij.v5i01.997

Abstract

Breast cancer ranks top of all types of cancer experienced by women with an average prevalence of 56.5 per 100,000 female populations in the world. In Indonesia, less than 68,858 cases (16.6%) of a total of 396,914 cases were recorded and more than 22,000 cases ended in death. (Sung et al., 2021). The life of a patient diagnosed with breast cancer will experience many changes in their physical and psychological condition, which will then affect the quality of life of the patient and will be a long-term problem if not treated. Individuals with good quality of life will have physical and mental health, which will enable them to live socially in society according to their role. T The research was conducted quantitatively using cross sectional designs. The sample was used by 75 respondents who met the inclusion criteria of the population at the Hospital. The dependent variable is the quality of life of breast cancer patients, while the independent variables are age, marital status, lifestyle, body mass index, and stage of cancer. Data is collected using EORTC QLQ-C30 questionnaire, which are then analyzed by validating SPSS with an ordinal regression test. The results of the study showed that there was no influence between age (p=0.891), lifestyle (p =0.247), body mass index (p_0.294), and stage of cancer (p−0.268). Whereas for marital status(p=0,000) there was influence on the quality of life of patients with breast cancer.
Therapeutic Synergy of Combination of Kaempferia galanga and Zingiber officinale Extracts on Hyperuricemia-Induced Arterial Stiffness Hasimun, Patonah; Muzaki, Yoga Adi Restu; Sodik, Jajang Japar; Sukmawati, Ika Kurnia; Kusriani, Herni
Indonesian Journal of Pharmaceutical Science and Technology Vol 12 (2025): Vol. 12 Suppl. 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i0.59175

Abstract

Hyperuricemia, characterized by high uric acid levels, is associated with an elevated risk of cardiovascular diseases. Xanthine oxidoreductase (XOR), an enzyme central to uric acid generation, is implicated in oxidative stress and diminished vascular function. It has become a focal point for potential therapeutic interventions. This investigation aimed to assess the influence of combined ethanol extracts of Kaempferia galanga L. and Zingiber officinale (KGZE) on xanthine oxidase activity and arterial rigidity in hyperuricemic rat models. Furthermore, the research sought to explore these extracts' potential in managing hyperuricemia and its associated vascular disorders. Hyperuricemia was established in Wistar rats by administering potassium oxonate at 4.5 mg/kg via injection. A total of 25 rats were divided into five groups: a normal control group receiving 0.5% CMC, a positive control group with hyperuricemia, a reference group treated with allopurinol (1.8 mg/kgBW), and two experimental groups receiving KGZE at doses of 50 mg/kgBW and 100 mg/kgBW. All rats consumed 25% fructose in their drinking water for 28 days. This study measured uric acid levels and arterial stiffness, revealing that KGZE significantly reduced uric acid levels and improved arterial stiffness, indicating its potential as an XOR inhibitor.
Co-Authors Adinda, Deistha Afief, Arief R. Afria Hilda Restu Agustin, Ia Nurfauziah Ajeng Pramesti Akhamad Priyadi Anbar Fatin, Mia Nisrina Ani Anggriani, Ani Aqila Fadia, Andira Arif Rubianto Aris Suhardiman Asep Kamal Sahroni Astira Kosmawati Budiana, Wempi Dadang Juanda Deden Indra Dinata Deni Iskandar Destia Tresna Prima Elvira Najwa Zain Nabawi Fajarrini, Uvika Nurul Fatmawati, Eva Fatmawati, Fenti Fenti Fatmawati Fenti Fatmawati Garnadi Jafar, Garnadi Hasimun, Patonah Helen Fitri Novianti Hilda Restu, Afria Hilman Mulyana, Hilman Ida Lisni Ika Kurnia Sukmawati Ilham Bintang, Muhamad Irfani, Abdul Mulki Isviyanti Isviyanti Lia Marliani M. Ramadhan, Saputro Maharani, Ilmi Intan Mamay M Sobandi Mamay Maulana Sobandi Marita Kaniawati Maulana Sobandi, Mamay Mia Nisrina A Mia Nisrina Anbar Fatin Muhamad Reza Pahlevi Muhamad Reza, Pahlevi Mulki Irpani, Abdul Muzaki, Yoga Adi Restu Nita Selifiana Patonah, Patonah Pratama, Reza Priyadi, Akhmad Purwaniati, Purwaniati Putriyanti, Al-fira Ratu Fania Aprilyanti Reza Pratama Reza, Pratama Riyadi, Imam Roganda Situmorang Roni, Asep Rusi Rismawanti Ruswanti, Seffi Sabarudin, Cecep Saidah Mutmainah, Siti Sanggo, Merylance Stefany Selifiana , Nita Selifiana, Nita Siti Nurfitria, Rizki Siti Pandanwangi TW Sukmawati, ika kurnia Sumbara Sumbara Sutrisno, Entris Wahyudi, Fikri Mourly Wahyudin Wempi Budiana Wempi Budiana Widhya Aligita Yakobus Lau De Yung Sinaga Yani Mulyani Yuli Astuti Zaelani, Diki Zaelani, Diki Ziska, Rahma Zuniarto, Ahmad Azrul