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PERBANDINGAN DAYA HAMBAT TERHADAP PERTUMBUHAN BAKTERI Staphylococcus epidermidis ANTARA SERBUK SIMPLISISA KULIT DAUN & DAGING DAUN LIDAH BUAYA (Aloe vera(L.)Burm.f) Alma Dhita Shafira; Minda Sari Lubis; Gabena Indrayani Dalimunthe; D. Elysa Putri Mambang
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 3 No. 1 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v3i1.2379

Abstract

Bakteri Staphylococcus epidermidis merupakan satu dari tiga spesies bakteri gram positi Staphylococcus yang sering dijumpai. Staphylococcus epidermidis adalah flora normal pada kulit, saluran napas, dan saluran cerna manusia. Salah satu tanaman yang memiliki daya hambat terhadap pertumbuhan bakteri yaitu tanaman lidah buaya (Aloe vera L.)Burm.f Penelitian ini bertujuan untuk mengetahui perbandingan daya hambat antara serbuk simplisia kulit daun dan daging daun lidah buaya terhadap pertumbuhan bakteri Staphylococcus epidermidis. Metode penelitian ini adalah metode eksperimental, dengan melakukanerbandingan daya hambat terhadap pertumbuhan bakteri Staphylococcus epidermidis antara serbuk simplisia kulit daun dan daging daun lidah buaya (Aloe vera (L.)Burm.f.,. Data yang diperoleh dianalisis secara deskriptif kualitatif berupa diameter zona hambat. enelitian ini menggunakan rancangan penelitian deskriptif kualitatif yang bersifat memaparkan, menguraikan serta untuk mendapatkan gambaran daya hambat serbuk simplisia kulit daun dan daging daun lidah buaya terhadap bakteri Staphylococcus epidermidis. Hasil yang diperoleh menunjukkan bahwa serbuk simplisia kulit daun lidah buaya pada konsentrasi 6,25%, 12,5%, 25%, dan 50% termasuk kategori resistant (lemah). Begitu juga serbuk simplisia daging daun lidah buaya pada konsentrasi 6,25%, 12,5%, 25%, dan 50% termasuk kategori resistant (lemah) dan serbuk simplisia keseluruhan bagian daun lidah buaya pada konsentrasi 6,25%, 12,5%, 25% juga termasuk kategori resistant (lemah) sedangkan konsentrasi 50% termasuk kategori intermediate (sedang). Dapat disimpulkan bahwa serbuk simplisia kulit daun, daging daun serta kombinasi kulit dan daging daun lidah buaya memiliki daya hambat terhadap pertumbuhan bakteri Staphylococcus epidermidis dan hanya sampel kombinasi kulit dan daging daun lidah buaya dengan konsentrasi 50% yang memiliki daya hambat terbesar.
ISOLASI AMILOPEKTIN DARI PATI KULIT PISANG RAJA (Musa paradisiaca L) YANG BERPOTENSI SEBAGAI FILM COATED TABLET Adela Octi Dwiyani; Gabena Indrayani Dalimunthe; Minda Sari Lubis; Rafita Yuniarti
FARMASAINKES: JURNAL FARMASI, SAINS, dan KESEHATAN Vol. 3 No. 1 (2023): FARMASAINKES: JURNAL FARMASI, SAINS dan KESEHATAN
Publisher : Fakultas Farmasi Universitas Muslim Nusantara Al Washliyah

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32696/farmasainkes.v3i1.2380

Abstract

Pati merupakan polisakarida yang jumlahnya melimpah pada sel-sel tanaman. Pati mengandung amilosa dan amilopektin, dimana amilopektin dapat digunakan sebagai salah satu bahan dasar pembuatan film coated atau pelapis permukaan seperti tablet. Tujuan penelitian ini adalah untuk mengisolasi amilopektin dari pati kulit pisang raja (Musa paradisiaca L.) berdasarkan karakteristiknya dan melalui uji iodin dan melihat dari gugus yang dihasilkan dengan menggunakan spektrofotometer IR. Berdasarkan dari hasil rendemen yang didapatkan berdasarkan perhitungan perbandingan antara berat pati dengan berat kulit pisang segar yaitu 3.33%. Setelah dilakukannya perhitungan persen rendemen isolasi amilopektin dengan cara membandingkan antara berat tepung amilopektin dengan berat pati, maka didapatkan hasil rendemen 72.67%. Hasil organoleptiknya yaitu berbentuk serbuk, berwarna coklat dan tidak berbau sesuai syarat SNI 3451:2011, kadar abu total 3% masih memenuhi syarat MMI edisi III dengan hasil dari ketiga pengulangan yaitu 1.4%, 1.2%, dan 1.3%, hasil uji iodin berwarna merah violet dan hasil analisis gugus menggunakan FTIR terdapat tiga gugus fungsi utama yang merupakan karakteristik dari amilopektin yaitu C-H, O-H dan C=O. Kesimpulannya serbuk yang dihasilkan merupakan serbuk amilopektin yang diisolasi dari pati kulit pisang raja.
Skrining fitokimia, formulasi dan uji mutu fisik nanoserum ekstrak bonggol nanas (Ananas comosus (L.) Merr) Rahma Maulidia Fitri; Minda Sari Lubis; Gabena Indrayani Dalimunthe; Rafita Yuniarti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 3 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i3.207

Abstract

Nanoserum is a slightly viscous transparent or semi-transparent preparation whose particle size is smaller than conventional serum. The purpose of this study was to find out that pineapple hump extract contains secondary metabolites, has physical quality and has a good level of stability in the form of nanoserum. The method used in this research is experimental, the sample used is pineapple hump. The data collected is in the form of quantitative and qualitative. The results showed that pineapple hump extract contains secondary metabolites of alkaloids, flavonoids, tannins, saponins, steroids, glycosides. Organoleptic test all formulas have a clear and transparent color. In the particle size and polydispersibility index tests (F0), (F1), (F2), (F3), all formulas showing particle size and polydispersibility index met the requirements of <1000 nm and polydispersibility index <0.5. Percent transmittance test (F0), (F1), (F2), (F3), all formulas have clear and transparent visual appearance according to the requirements of 90%-100%. There was no change in the stability level of nanoserum in the organoleptic test, the particle size test and the polydispersibility index (F0), (F1), (F2), (F3). There is a change in particle size and polydispersibility index afterCyling test, however, it is still categorized as good because it is in the range of quality requirements, namely <1000 nm and the polydispersibility index <0.5.
Uji aktivitas antibakteri fraksi n-heksana dan etil asetat daun kecombrang (Etlingera elatior) terhadap Staphylococcus aureus dan Escherichia coli Alfi Wahyudi Nasution; Haris Munandar Nasution; Minda Sari Lubis; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.228

Abstract

Infectious diseases caused by microorganisms are diseases that are commonly found in society. The therapy used to treat infections today by administering antibiotics. However, many cases of bacterial resistance to antibiotics are caused by the irrational use of antibiotics, so is necessary to develop alternatives to antibiotics derived from plants. glycosides that can function as antimicrobials. This study aims to determine the activity of the n-hexane and ethyl acetate fractions from kecombrang leaves against Staphylococcus aureus and Escherichia coli. This research was conducted experimentally, the independent variables consisted of the ethanol extract of kecombrang leaves, n hexane and ethyl acetate fractions. The dependent variable consisted of simplicia characteristic test, kecombrang leaf phytochemical screening, antibacterial activity test of kecombrang leaf fraction against S.aureus and E.coli. Antibacterial test using n-hexane and ethyl acetate fractions made with concentrations of 10%, 30%, 50% and 70%. the positive control used the antibiotic chloramphenicol and the negative control used DMSO, and the method used was agar diffusion using paper discs.The results of the antibacterial test showed that kecombrang leaves had an inhibitory effect on Staphylococcus aureus and Escherichia coli bacteria. The inhibition power of the ethyl acetate fraction was stronger than n hexane. The strongest inhibition was found in the ethyl acetate fraction with a concentration of 30.50 and 70% against Staphylococcus aureus, namely 10.9 mm, 12.6 mm and 14.15 mm. whereas in Escherichia coli bacteria, namely 10.5 mm, 12.3 mm. and 13.9mm. and based on the CLSI inhibition zone category, 2020, the concentration fraction of 70% is in the intermediate category, concentrations of 50, 30, and 10% are in the resistant category. While the positive control is categorized as sensitive to both bacteria.  
Uji aktivitas antibakteri formulasi sediaan sabun padat transparan ekstrak daun belimbing wuluh (Averrhoa bilimbi L.) terhadap bakteri Cutibacterium acnes Siti Aisyah Jamil; Yayuk Putri Rahayu; Minda Sari Lubis; Haris Munandar Nasution
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.234

Abstract

Acne is a skin disease that begins with an increase in sebum production which is exacerbated by an attack by the Cutibacterium acnes bacteria. Currently, there are many anti-acne preparations, one of which is in the form of soap, but only a few contain natural herbs. One plant that has an active substance or agent that has the potential to prevent and treat acne leaves belimbing wuluh (Averrhoa bililmbi L.) with its antibacterial properties. Besides having the potential to prevent and treat acne, this plant is also very easy to find in Indonesia. This research was conducted to see whether starfruit leaf extract could be formulated as soap preparation and whether it had antibacterial properties against Cutibacterium acnes. The research method for fresh starfruit leaves was made into Simplicia and extracted using 96% ethanol, phytochemical screening was carried out on fresh starfruit leaves and extracts. Transparent solid soap formulation with belimbing wuluh leaf extract with concentrations of 2.5%, 5%, and 7.5%. Evaluation preparations included physical quality tests, pH tests, foam height and stability tests, skin moisture tests, irritation tests, Panelist preference tests, and antibacterial activity against Cutibacterium acnes. The results and conclusions show that fresh starfruit leaves and extracts contain compounds belonging to class alkaloids, flavonoids, saponins, tannins, steroids/triterpenoids, and glycosides. Belimbing wuluh leaf extract can be formulated into transparent solid soap preparation, has a distinctive aroma extract, is homogeneous, pH 9-11, with spreadability 26-29mm. Antibacterial activity included the insensitive category at all concentrations. The panelist's preferred formula was preparation with a concentration of 2.5%
Sediaan krim ekstrak jeruk nipis (Citrus aurantifolia S.) Sebagai Obat luka sayat pada mencit jantan (Mus musculus) Madani Sirait; Gabena Indrayani Dalimunthe; Minda Sari Lubis; D. Elysa Putri Mambang
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.235

Abstract

Indonesia is a country that is rich in plant diversity. One of them is lime, which is used as a traditional wound medicine. Lime contains essential oil compounds, flavonoids, saponins, tannins, alkaloids, citric acid, amino acids, vitamin B1, and vitamin C. Based on previous research, flavonoids, tannins, and saponins can heal wounds. Making simplicia using an oven at 50oC  and characterizing simplicia Extraction using the maceration method with 96% ethanol is then concentrated using a rotary evaporator. Orientation on the preparation of the cream was carried out until a good cream texture was found, and a cream preparation test was carried out to comply with the requirements in the literature. The test animals used were 24 male mice, which were divided into six treatment groups. The first group was treated with betadine, the second group was treated with cream without extract, the third group was treated with 2 grams of extract cream, the fourth group was treated with 3 grams of extract cream, the fifth group was treated with 4 grams of extract cream, and the sixth group was untreated. Each group was given a 10-mm wound. Based on the treatment carried out for 14 days, the best formulation was a 4-gram lime extract cream, and the wound healed on day 9, which was the same as the comparison used, namely betadine.
Skrining Fitokimia, Formulasi, dan Karakteristik Fisik Sediaan Soothing Gel Daging Daun Lidah Buaya (Aloe vera (L.) Burm.f.) Rosalinda Mahdalena Sinaga; Minda Sari Lubis; Gabena Indrayani Dalimunthe; Yayuk Putri Rahayu
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.274

Abstract

The content of aloe vera (Aloe vera (L.) Burm.f.) can make the skin not dry quickly and feel moisturised. Soothing gel is a preparation that works effectively to restore skin moisture, provide comfort and a cooling effect on red and irritated skin so that the skin condition returns to normal and prevents skin dryness. The study aimed to determine the various secondary metabolites in aloe vera leaf flesh, to determine differences in concentrations of aloe vera leaf flesh in soothing gel preparations on the physical characteristics of the practices and to determine material changes before and after stability tests were carried out using the cycling test method. The research method was used experimental, with the independent variables varying the aloe vera leaf flesh concentration 0% (blank), 1%, 2%, and 3%, and the dependent variable secondary metabolites and physical characteristics. The sample preparation method is wet sorting, and other methods used are phytochemical screening, viscometry, and cycling tests. The results of the phytochemical screening showed that aloe vera leaf flesh contains secondary metabolites of flavonoids, glycosides, tannins, saponins, and steroids. The results of the soothing gel formulation with variations in the aloe vera leaf flesh concentration of 0%, 1%, 2%, and 3% showed differences in colour, distinctive aroma, consistency, spreadability, adhesion, pH, and viscosity that met the requirements. The stability test results using the cycling test method showed physical changes in consistency, spreadability, adhesion, pH, and viscosity. However, these changes still met the requirements for good gel preparation according to SNI 16-4399-1996.
Pembuatan mikrokristalin selulosa dari ubi jalar (Ipomoea batatas (L.) Lamk.) dengan Avicel PH 102 sebagai pembanding dan evaluasi mutu fisik Shinta Mida Ariani Harahap; Gabena Indrayani Dalimunthe; Minda Sari Lubis; Rafita Yuniarti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.297

Abstract

Microcrystalline cellulose is an excipient used in the manufacture of directly felt tablets, namely as a filler, binder, and crushing agent and can be isolated from fibrous plants. One of the abundant fibrous plants in Indonesia is sweet potato (Ipomoea batatas L.). The main chemical composition of sweet potatoes includes carbohydrates, namely dietary fibre (hemicellulose, cellulose), starch, and several types of sugar. The objective of this research was to make microcrystalline cellulose from sweet potato (Ipomoea batatas L.) and see the comparison of physical quality evaluation of microcrystalline cellulose results from sweet potato (Ipomoea batatas L.) with Avicel PH 102. This research used the hydrolysis method of HCl 2.5 N acid by heating at a temperature of 105ºC for 10-15 minutes with the ratio of alpha-cellulose and acid used is (1: 20). Then, evaluated the physical quality of microcrystalline cellulose from sweet potatoes by organoleptic tests, identification, pH determination, solubility of substances in water and drying loss. The results of this research show that sweet potato cellulose can be used as microcrystalline cellulose, namely with the results of a physical quality evaluation that meets the requirements when compared to Avicel PH 102; each includes organoleptic where both are in powder form, do not have the same smell and taste, but there are differences in colour where Avicel PH 102 is white. In contrast, microcrystalline sweet potato cellulose is yellowish-white. On identification, both produce violet blue; pH 5.2 and pH 6.5; solubility of substances in water 0.2% and 0.1%; drying shrinkage of 0.71% and 2.53%; And in the starch test, both did not produce a violet-blue solution.
Pembuatan mikrokristalin selulosa dari wortel (Daucus carota L.) dengan avicel PH 102 sebagai pembanding dan evaluasi mutu fisik Chairina Milda; Gabena Indrayani Dalimunthe; Minda Sari Lubis; Rafita Yuniarti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.298

Abstract

Carrots (Daucus carota L.) are vegetable types of annuals because they only produce once and then die. Carrot tubers are reddish-yellow due to the high content of carotene. Microcrystalline cellulose is one of the excipients (additives) in tablet preparations, namely as a filler, which is considered a binding agent because it can increase the compactness ability of tablets from compression mixtures. Microcrystalline cellulose comes from natural resources containing lignocellulose fibers such as wood and non-wood. One of the abundant fibrous plants in Indonesia is carrots (Daucus carota L.). The main chemical composition of carrots includes carbohydrates, namely dietary fiber (hemicellulose, cellulose), starch, and several types of sugar. This research aimed to determine whether carrot cellulose (Daucus carota L.) can be made into microcrystalline cellulose and compare the physical quality of carrot cellulose microcrystalline results with Avicel PH 102. Microcrystalline cellulose is made by a delignification process using 15% NaOH, followed by a bleaching process using 3.5% NaOCl, and then continued with a hydrolysis process with HCl 2.5N. Then, microcrystalline cellulose is carried out a physical quality evaluation, which includes organoleptic, identification, pH, solubility of substances in water, shrinkage of dryers, and starch. The results of the research showed that carrots can be made into microcrystalline cellulose, namely with the results of physical quality evaluation compared to Avicel PH 102, organoleptic powder, odorless, tasteless, and yellowish white (microcrystalline cellulose) and white (Avicel PH 102); identification, each of which produces a blue-violet color; pH 5.67 and 6.5; the solubility of substances in water is 0.1% each; drying shrinkage 4.70% and 2.53%; and starch, respectively not formed violet blue solution.
Efektivitas penyembuhan luka bakar menggunakan salep ekstrak etanol daun ciplukan (Physalis angulata L.) pada kelinci Cindy Marlina Tambunan; Gabena Indrayani Dalimunthe; Minda Sari Lubis; Rafita Yuniarti
Journal of Pharmaceutical and Sciences JPS Volume 6 Nomor 4 (2023)
Publisher : Fakultas Farmasi Universitas Tjut Nyak Dhien

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36490/journal-jps.com.v6i4.300

Abstract

Indonesian people have long used plants as medicine and for health maintenance, which is inherited from generation to generation. One plant that can be used in traditional medicine is the ciplukan plant (Physalis angulata L.), which is a small plant that can grow anywhere. It turns out not only has a unique taste but is also beneficial for health; ciplukan can be used to treat flu and sore throat, whooping cough, bronchitis, mumps, ulcers, and also Ayan or epilepsy. Empirically, the use of ciplukan plants functions as a cure for smallpox, which has been used by the community by bathing. Smallpox is shaped like a blistered burn and will be shaped like an ulcer. So, researchers are interested in developing in the form of ointment because it is more effective to use and can be taken anywhere. This research was conducted to determine that ethanol extract of ciplukan leaves can be formulated on the basis of absorbent ointment and to determine the healing effect of burns in rabbits from the preparation of ethanol extract ointment of ciplukan leaves (Physalis angulata L.). Ciplukan leaf extract is made from simplicial ciplukan leaves by maceration method and then tested for the effectiveness of healing burns on rabbits using ointment. The ointment is made in 4 formulations, namely F0, F1 (10%), F2 (15%), and F3 (20%) using white Vaseline as the ointment base. Evaluation of ointment preparations includes physical stability (shape, smell and colour, homogeneity, pH, dispersion, adhesion and viscosity. All formulas of ointment preparations are good in storage. In ointment preparations in the homogeneity test, all formulas are homogeneous. In pH inspection, dispersion, adhesion and viscosity all meet requirements according to predetermined or established standards. Ciplukan leaf extract can be formulated into an ointment dosage form. Ointment preparations with a high concentration are most effective in healing burns in rabbits.
Co-Authors A'dilah, Nur Adani, Bazlina Adela Octi Dwiyani Adjelie, Tiara Afifah, Puan Ibni Alfi Wahyudi Nasution Alma Dhita Shafira Amaliana, Amaliana Andjelie, Tiara Anggraini, Dea Puspa Anny Sartika Daulay Anugrah, Bayu Ariandi Arianti, Sellin Arina Aulia Fitri, Aulia Aulia, Meisyah Ayuningrum, Annisa Bambang Hermanto Bilal, Mohd. Chairina Milda Cindy Marlina Tambunan Cut Dian Mala Luthfia D Elysa Putri Mambang D. Elysa Putri Mambang D. Elysa Putri Mambang D.Elysa Putri Mambang Dama Yanti, Fradilla Debi Meilani Dena, Mutia Denni Bahari Dewa, Fasca Dewi, Sri Harti Dikki Miswanda Dinda Sari Utami Efendi, Tania Tiara Ellyza, Chella Emmy Wiriandini Fauziah Zain Fithri Pulungan, Ainil Fitri Febriani Fitri, Nurul Fitri, Raissa Gabena Indrayani Dalimunthe Haris Munandar Nasution Hasibuan , Fika Miah Sasmitha Hendraputra, Hardy Handoko Heru Adha Prayogo Husna, Miftahul Hutagalung , Septi Ratna Cempaka Hutagalung, Riris Br Hutagalung, Victor H Ika Fitriani Indah Nasution Inna Myesha Junia Fitri Hayani Juwita, Sukma Karismawati Karlina Butar Butar Khoyrill Muttiin Kiki Rawitri Krisna Juniharta Napitupulu Lestari, Seri Lestari, Sri Indah Linda, Rosa Lisda Mayanti Lubis, Asira Lubis, Nadya Frestika Lubis, Nurazizah Lubis, Zulkifli Ismail M. Arya Wiguna Madani Sirait maghfirah, Suci Mambang, D Elysa Putri Matondang , Fikriyah Hafni Maulana Putri, Yasinta Metami Sihombing, Juliana Meutia, Cut Meylisa Pratami Br Sinaga Miftahul Jannah Milwani Harahap Miranza, Nona Misna Rosalinda Hutabarat Muhammad Amin Nasution Muhammad Tegar Tri Rizky Nadia Salsabilla Nasri Nasri, Nasri Nasution , Muhammad Amin Nasution, M Pandapotan Nasution, M. Pandapotan Nasution, Vevi Sarah Nia Novranda Pertiwi Ningtias, Anggitha Novi Yuliandari Novita Sari, Helsa Novriani Putri Santia Nur Asia, Nur Nuratika, Eli Nurfadilla, Kiki Nurul Salsa Abya Ritonga Nurwijayanti Oktavia, Zela Pulungan, Anili Fithri Purba , Intan Sabila Putri Purba, Juvantri Fablo Puspita, Dinda Dila Puteri, Cut Intan Annisa Putri , Adilla Putri Rahayu, Yayuk Rafita Yuliarti Rahma Maulidia Fitri Rahmi, Sofia Ramadhan , Yusril Rambe, Sitiapsah Rapita Yuniarti Rati , Yuliandini Rezky , Deswita Ina Riani, Nur Aslin Ridwan Taher Lubis Ridwanto Ridwanto Rifqi, M. Ainur Rinda Sari, Syilvi Ritonga , Nur Sakina Ritonga , Septi Ani Ritonga, Oktavia Rkt, Chairunnisa Rohmah, Roihanah Rosalinda Mahdalena Sinaga Rosalinda Mahdalena Sinaga Safitri , Nurhaliza Sagita Marina Simatupang Sandika, M Teguh Sari, Syilvi Rinda Satri Situmorang, Rati Savika, Anggraini Selvicahyani, Selvicahyani Shinta Mida Ariani Harahap Sihotang, Laura Indah Restu silalahi, zahra salsabila Sinaga, Rosalinda Mahdalena Sindi, Sindi Siregar , Misbah Siregar , Runisya Maugin Utami Siregar, Hikmatussabaria Siregar, Rina Paramitha Siti Aisyah Jamil Siti Anisa Sitinjak, Iyustri Ririn Slamet Indarjo Sri Harti Sri Mulia Ningsih Siregar Sri Murni Sri Ria Ranti Sri Wahyuni Sri Wahyuni Sulwiyatul K Sani Supiyani, Supiyani Surendro, Yasmeen Nazhifah Amani Syafa Nadira Ashiilah Syafira, Nona Syafirna, Nada Tia Nazilla Titin Agustina Trisha Wulan Erja Ulmi, M Rayhan Ummu Safura Sirait Vera Estefania Kaban Vera Kristiana Wan Dian Safina Widya, Rizka Wilda Septia Winda Aulia Yadi, Hervi Yayuk Putri Rahayu Yayuk Putri Rahayu Yayuk Yuliana Yuni Sartika Yuniarti , Rafita Yuniarti, Rafita Yuniarti, Rapita Zahara, Fitria Siti Zahira Ahmad, Madani Zannah , Muhamad Ziza Putri Aisyia Fauzi Zulhij, Fizrya Zulmai Rani