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All Journal Biotropika Jurnal Sain Peternakan Indonesia Jurnal Biologi Tropis Jurnal Pengabdian Magister Pendidikan IPA JITPI : Jurnal Ilmu Dan Teknologi Peternakan Indonesia (Indonesian Journal of Animal Science and Technology) Jurnal Gema Ngabdi Best Journal (Biology Education, Sains and Technology) Buletin Peternakan Tropis (Bulletin of Tropical Animal Science) JAGO TOLIS : Jurnal Agrokompleks Tolis Tarjih Tropical Livestock Journal Jurnal Kolaboratif Sains CELEBES Agricultural Jurnal Pepadu JAS (Journal of Animal Science) Al-Aqlu : Jurnal Matematika, Teknik dan Sains Al-Qalbu: Jurnal Pendidikan, Sosial dan Sains Environmental and Agriculture Management International Journal of Food Sciences and Nutrition Innovations
Septian, I Gede Nano
Universitas 45 Mataram
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Cichorium intybus as a Functional Food: Bioactive Compounds and Antidiabetic Potential Amalyadi, Rezki; Karni, Ine; Aminurrahman, Aminurrahman; Septian, I Gede Nano
International Journal of Food Sciences and Nutrition Innovations Vol. 1 No. 2 (2025): International Journal of Food Sciences and Nutrition Innovations (December)
Publisher : CV. Media Inti Teknologi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58723/ijfsni.v1i2.62

Abstract

Background of study: Cichorium intybus L., or chicory, is a nutrient-dense plant that has traditionally been used as a forage crop and vegetable. It is now gaining attention for its bioactive compounds, which have therapeutic potential, particularly for managing type 2 diabetes mellitus.Aims and scope of paper: This systematic review examines the nutritional composition and phytochemical profile of chicory, as well as its antidiabetic mechanisms, to highlight its potential role in the prevention and management of diabetes as a functional food.Methods: A systematic literature review was conducted in accordance with PRISMA guidelines. Peer-reviewed articles published between 2019 and 2022 were identified using the databases Scopus, PubMed, and Web of Science. The eligible studies focused on chicory’s bioactive compounds and their metabolic effects. Data extraction and quality appraisal were performed using a standardized CASP checklist, and thematic synthesis was applied.Result: 36 studies were included. Chicory was found to be rich in inulin, phenolic acids (e.g., chicoric acid and caffeic acid), flavonoids (e.g., luteolin and quercetin), and sesquiterpene lactones. These compounds improve insulin sensitivity, inhibit carbohydrate-digesting enzymes, regulate lipid metabolism, and protect pancreatic beta cells via antioxidant and anti-inflammatory pathways. Chicory-derived ingredients are used in prebiotic formulations, functional foods, and animal feeds.Conclusion: Chicory has significant antidiabetic potential through multiple target mechanisms. However, the current evidence is primarily preclinical with few human trials. Standardized clinical studies are needed to validate its efficacy and determine the optimal dosage and long-term safety. Due to its accessibility and versatility, chicory is a promising functional food for supporting metabolic health and sustainable nutrition.
Co-Authors Al Gifari, Zaid amalia pratiwi, eva Aminurrahman Aminurrahman, Aminurrahman Anjani, Hikmah Rara Aryani Rahmawati Ashari, M. Azhary Noersidiq Baeti, Husnul Budi Indarsih Budi Indarsih, Budi Budi Satriya, I Nyoman Bulkaini (Bulkaini) Danial, Wahyu Denianto Yoga Sativa Dewi, Nurul Afriani Djoko Kisworo Dohi, Muhammad Dwi Kusuma Purnamasari, Dwi Kusuma Fadielah, Basri Fahrullah Fahrullah Fahrullah, Fahrullah Febrian Kusuma Atmanegara Fiarani, Mesil Fitriyan Fadjar Suryadi, Muh. Aidil Gifari, Zaid Al Haerunnisa Haerunnisa, Haerunnisa Hasma Hasma Hermansyah Hermansyah I Nyoman Sukartha Jaya Ihsan, Makbul Ikhwan Firhamsah Ine Karni Ine Karni Irwan Faezan Jaya, I Nyoman Sukartha Jufri, Afifah Farida Juliasis Mayagi Junia Ayu Ninggrum, ⁠Vidia Karni, Ine Khairil Anwar Kotta, Raismin Kurniawati Kurniawati Kurniawati Kurniawati lailatun nurjanah, luluk Made Sriasih, Made Mohammad Hasil Tamzil Muh. Aidil Fitriyan Fadjar Suryadi Muhamad Ali Muhammad Amin Muhsinin, Muhammad Musanip Musanip, Musanip Ni Ketut Dewi Haryani Ni Ketut Dewi Haryani, Ni Ketut Dewi Noersidiq, Azhari Novita Hidayatun Nufus Nurjanah, Luluk lailatun Oscar Yanuarianto, Oscar Pertiwi, Eva Amalia Poerwoto, Happy Putra, Ryan Aryadin Raismin Kotta Rezki Amalyadi Rina Andriati, Rina Rosyidi, Muhammad Subhan Bahruddin Sadia, I Nyoman Saedi, M. Ridwam Saedi, M. Ridwan Salahuddin Salahuddin Sativa, Denianto Yoga Suhardiani, Roro Agustien Suhardiani, Rr. Agustien Sukarne Sukarne Sulaiman Ngongu Depamede Sumadiasa , I Wayan Lanus Sumahiradewi, Luh Gede Suryadi, Muh. Aodil Fitriyan Fadjar Tamzil, Moh Hasil Tapaul Rozi Taqiuddin, Moh Umrah Umrah Unsunnidhal, Lalu Vebera Maslami Wandira, Ica Ayu Widiastuti, Lusia Komala Wiryawan, Ketut Gede Yulianto, Wahid Zaid Al Gifari