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Hubungan Frekuensi Harian Mencuci Wajah dan Pemakaian Sabun Wajah Anti Akne Dengan Derajat Keparahan Akne Vulgaris pada Remaja Putri di SMAN 10 Bandar Lampung Annisa Adietya Pratama; Dwi Indria Anggraini; Syazili Mustofa
MAJORITY Vol 10 No 1 (2021): MAJORITY
Publisher : Majority

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Abstract

Acne vulgaris is a skin problem that often occurs in teenager. Some factors that can cause acne vulgaris include genetic, hormonal, infection, trauma, and diet. The degree of acne is divided into mild, moderate, and severe degrees. Washing face is a prevention or treatment of acne vulgaris, it should be noted the use of the type of face wash and the frequency of facial washing with the incidence of acne vulgaris. Purpose of this research is to find out the relationship of daily frequency facial washing and use of anti acne face wash to the severity of acne vulgaris in teenage girl at SMAN 10 Bandar Lampung. This research used analytic observational method with cross sectional approach. The sample of the research is 89 respondents and using purposive sampling method. The result of univariate analysis was 56,2% of respondents use anti acne face wash and 57,3% of respondents wash their faces ≥ 3 times a day. The result of bivariate analysis showed some variables had a correlation with with the severity of acne vulgaris is the use of anti acne face wash (p value 0,016). Meanwhile, some variables had no correlation with the severity of acne vulgaris witch is the frequency of daily facial washing (p value 0,582). The conclusion is there was relationship between the use of anti acne face wash and the severity of acne vulgaris and there was no relationship between daily frequency facial washing with the severity of acne vulgaris
Prevalensi Kolonisasi Bakteri Methicillin-Resistant Staphylococcus aureus (MRSA) di Ruang Intensive Care Unit (ICU) Rumah Sakit Umum Daerah Abdul Moeloek Bandar Lampung Hasril Mulya Budiman; Tri Umiana Soleha; Efrida Warganegara; Dwi Indria Anggraini
MAJORITY Vol 9 No 1 (2020): MAJORITY
Publisher : Majority

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Abstract

Methicillin-Resistant Staphylococcus aureus (MRSA) is a bacterium Staphylococcus aureus which has a resistance to methicillin and some beta-lactam antibiotics. MRSA can colonize as normal flora in some parts of the human body, such as the nose, skin, hands, perineum, and other parts of the body. Intensive Care Unit (ICU) is the high risk areas for MRSA transmission. The purpose of this study was to determine the prevalence of MRSA in ICU of Regional General Hospital Abdul Moeloek Bandar Lampung. The method used in this study was cross sectional. The primary data used in this research were obtained by collecting a nasal and hand swab of patients treated in the ICU at one time and then identify the MRSA bacteria in laboratory to determine its prevalence. The results of bacterial identification on the nose and hand specimen showed 15 out of 40 samples tested positive for MRSA (37.50%). The results of the identification of bacteria MRSA shows the prevalence of MRSA colonization of the nose specimen at 17.50%, hand amounted to 32.50%, and which are both positive at 12.50%. Based on the research that has been done, it can be concluded there is a prevalence of colonization of the MRSA bacteria in ICU of Regional General Hospital Bandar Lampung Abdul Moeloek is 37.50%.
Faktor-Faktor yang Mempengaruhi Derajat Kecacatan Kusta Fauziani, Andra Nabila; Anggraini, Dwi Indria; Hanriko, Rizki; Sibero, Hendra Tarigan
Medula Vol 14 No 1 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i1.936

Abstract

Morbus Hansen, also known as leprosy, is an infectious disease that is chronic or chronic. This disease is caused by the acid-fast bacillus (BTA) Mycobacterium leprae which is obligate intracellular. This disease can attack various body systems, including the peripheral nervous system, skin, mucosa, upper respiratory tract, reticuloendothelial system, eyes, muscles and bones. Based on WHO data for 2021, globally there were 133,781 cases of leprosy, with Indonesia ranking third highest in the world with 10,976 new cases after India and Brazil. Leprosy that is not treated properly can cause disability. There are two types of disability in leprosy, namely primary and secondary disability. Primary disability is caused directly by the Mycobacterium leprae bacteria, while secondary disability is a disorder that arises because the primary disability is not treated properly. The level of disability in leprosy is classified based on symptoms of damage to the eyes, hands and feet with levels 0, 1 and 2. Factors that influence the degree of disability in leprosy are grouped into demographic factors, internal factors and external factors. Demographic factors include age, gender, socio-economic status, occupation, and education level. Internal factors include the type of leprosy, length of suffering, number of nerves affected, and leprosy reaction. External factors include compliance with taking medication, delays in treatment, and self-care.
Faktor-faktor yang Mempengaruhi Keberhasilan Terapi Pasien Kusta Sagia, Nabilla Alsa; Anggraini, Dwi Indria; Wulan, Anggraeni Janar; Sibero, Hendra Tarigan
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.937

Abstract

Leprosy is a chronic granulomatous infectious disease caused by the obligate intracellular bacterium Mycobacterium leprae (M. leprae). This disease comes from the Latin word "lepros" which means scale. M. Leprae bacteria enter the human body through 2 main routes, namely through the skin and the upper respiratory tract. Leprosy bacilli enter the human body through direct contact with the skin or nasal mucosa originating from droplets. Bacteria from droplets will survive for 2 days in a dry environment, even up to 10 days in a humid environment and low temperatures. The success of therapy for Morbus Hansen patients is expressed by RFT (Release from Treatment). RFT can be stated after the dose is fulfilled without having to undergo laboratory examination. PB (paucibacillary) patients who have received 6 doses (blister) of treatment within 6-9 months are declared RFT, without having to undergo a laboratory examination. MB (multibacillary) patients who have received 12 doses (blister) of MDT treatment within 12-18 months are declared RFT, without having to undergo a laboratory examination. The factors that play a role in the success of therapy for leprosy patients are age, gender, education, employment, knowledge, compliance with taking medication, and family support.
Anatomi dan Fisiologi Ginjal: Tinjauan Pustaka Alwiyah, Fadilah; Rudiyanto, Waluyo; Anggraini, Dwi Indria; Windarti, Indri
Medula Vol 14 No 2 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i2.977

Abstract

The kidneys are retroperitoneal organs located at the top on both sides of the III lumbar vertebra and attached directly to the abdominal or ventral wall of the M. psoas major and M. quadratus lumborum. The kidneys function to regulate the amount and concentration of ECF electrolytes and maintain nerve and muscle excitability, activating vitamin D which is important for calcium absorption in the digestive tract and producing erythropoietin which is a hormone to stimulate the bone marrow to form red blood cells. The main function of the kidneys is to filter and excrete metabolic waste products in the urine so that administration of toxic compounds or irritating compounds can cause degenerative changes such as fatty degeneration to necrosis of the kidneys. Disorders of the kidneys can disrupt kidney function. Chronic Kidney Disease (CKD) sufferers have several complications such as overhydration, hyperkalemia, metabolic acidosis, mineral and bone disorders, hypertension, anemia and dyslipidemia. The most common etiologies of CKD in adult patients are diabetes mellitus and hypertension. In children, the most common primary cause of PGTA is congenital abnormalities of the kidneys and urinary tract (such as obstructive uropathy, vesicoureteral reflux, renal dysplasia). Indonesian Nephrology Association (PERNEFRI) in 2006, which found that the prevalence of Chronic Kidney Disease (CKD) was 12.5%. Meanwhile, data according to the 2019 Health Insurance Administration (BPJS) shows that there were 1.93 million cases of kidney failure and 1.79 million cases in 2020. With this data, the author is interested in discussing the kidneys in more depth.
Hubungan Usia, Jenis Kelamin, Dan Pekerjaan Dengan Kejadian Dermatofitosis di Rumah Sakit Umum Daerah Dr. H. Abdul Moeloek Provinsi Lampung Periode 2017- 2021 Graceciela, Yohana Eva; Anggraini, Dwi Indria; Himayani, Rani; Sibero, Hendra Tarigan
Medula Vol 14 No 6 (2024): Medula
Publisher : CV. Jasa Sukses Abadi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53089/medula.v14i6.1097

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Dermatophytosis is a dermatophyte fungal infection that attacks keratinized tissues. This disease can be caused by various internal and external factors. The internal risk factors causing dermatophytosis include age, gender, and occupation. In addition to that, this study aimed at determining the relationship between age, gender, and occupation toward dermatophytosis cases. This study used an analytical observational design with a cross-sectional approach. The sample in this study consisted of 114 patients with dermatophytosis sourced from the secondary data in the form of medical records. The research data were conducted by using total sampling technique in RSUD Dr. H. Abdul Moeloek Lampung Province. The recorded data included the patients’ age, gender, occupational, and diagnosis. Then, the data were analysed using chi-square test presented in tabular form. The results showed that the majority of dermatophytosis patients were adults, female, and employees who worked in government/private institutions. The results of the chi-square test showed a significant value for the age variable (p = 0.035) and the gender variable (p = 0.041), while for the work variable there was no significant relationship (p = 0.615). There is a significant relationship between age and gender with the dermatophytosis cases and there is no significant relationship between occupation and the dermatophytosis cases.
Transforming clinical clerkship processes with integrated information systems Septama, Hery Dian; Hakim, Lukmanul; Muhammad, Meizano Ardhi; Rahmayani, Fidha; Anggraini, Dwi Indria; Lania, Siska; Bestak, Robert
International Journal of Electrical and Computer Engineering (IJECE) Vol 14, No 3: June 2024
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijece.v14i3.pp3036-3044

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There are still many manual administrative processes involved in clinical clerkships. However, digital technologies and software solutions can significantly improve medical education. This paper aims to utilize extreme programming (XP) as a methodology for developing the information system. A total of 23 user stories have been planned for completion. The priority of each requirement stated in the user stories is determined using the MoSCoW prioritization technique. The results indicate that the software successfully passed all tests among the 23 black box testing scenarios. Developing an integrated information system to streamline clinical clerkships has been successfully achieved. The user experience questionnaire (UEQ) is utilized to gather the perspectives of hospital management and medical faculty members regarding the information system. The average scores for each category are as follows: 1.93 for attractiveness, 2.04 for perspicuity, 2.20 for efficiency, 2.06 for dependability, 2.14 for stimulation, and 1.85 for novelty. Therefore, it can be concluded that all existing user experience scales exhibit an outstanding degree of user satisfaction.
Tatalaksana Oral Non-Antimikroba Pada Pasien Akne Vulgaris Ayu Wulandari; Dwi Indria Anggraini
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 8 No 2 (2020): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 8.2 Edisi Maret - Agus
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v8i2.117

Abstract

Introduction: Acne vulgaris (acne) is a non-infectious skin condition that is very common and often comes in dermatological practice. Because acne often appears chronic and can last for years, safe and effective long-term therapy is needed. Given the increasingly frequent antibiotic-resistant bacteria and the severity of the consequences if there is resistance, dermatologists are needed to maximize the use of non-antimicrobial therapy when treating patients with acne. Objective: To find out which oral non-antibiotic drugs can be used for acne vulgaris therapy Method: The article was prepared using the literature review method, involving 32 literature sourced from books and journals. Results: The emergence and potential transfer of antibiotic resistance in skin microorganisms is of current concern in treatment especially in the context of dermatology where long-term treatment with antibiotics. Remarkably, non-antibiotic therapy in the form of isotretinoin - non-antimicrobial retinoids is effective in reducing or eradicating anaerobic Propionibacterium acnes that is causally involved in the pathogenesis of the Acne vulgaris complex. Discussion: In this review of the literature we present data on the effects of the proper use of non-antimicrobial therapy for acne. There are various topical and oral treatment options that can be used gradually according to the severity and therapeutic response of the patient. Non-antimicrobial treatments can be very good at controlling acne, especially when used as maintenance therapy. While antibiotics have a role in the treatment of acne, they should not be used as monotherapy, and the use of old antibiotics is not recommended. Conclusion: Some drugs whose hormonal mechanism can be oral non-antimicrobial drugs in the treatment of acne vulgaris Keywords: Acne, Antibiotics, Isotretinoin, Spironolactone, Subantimicrobial
Terapi Imunologi Pada Melanoma Muhamad Addin Syakir; Dwi Indria Anggraini
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 8 No 2 (2020): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 8.2 Edisi Maret - Agus
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v8i2.118

Abstract

Introductions: Immunotherapy for cancer is used based on the principle of the disease that the immune system is able to produce an immune response to tumor cells. Treatment is currently available for selective melanoma patients based on the response rate of the disease. Objectives: To determine the management of melanoma using immunology. Methods: This article was compiled using the literature review method, using 32 sources derived from journals and books. Results: Interferon-? was approved for the treatment of adjuvant stage III melanoma with increased survival rate. New and more innovative approaches are needed with increasing therapeutic effects. The prognosis of patients with metastatic melanoma in the world has changed dramatically since the presence of an immune checkpoint inhibitor. Discussions: Ipilimumab, which targets the cytotoxic T lymphocyte-associated protein 4 (CTLA-4) protein is the first agent that exists. Furthermore, nivolumab and pembrolizumab that bind to programmed death protein 1 (PD-1) proteins have been shown to be more effective and lower in toxicity than ipilimumab. The combination of nivolumab or pembrolizumab with ipilimumab has resulted in increased response rates and patient survival rate results. This literature review will explore important clinical trial data that have led to the use of this immunotherapy agent in the world and some clinical trial results currently reported for new combination therapies. Conclusions: At present immunology therapy for melanoma management can be applied. Keywords: Chemotherapy, immunotherapy, management, melanoma
Penggunaan Ester Asam Fumarat Oral Dalam Pengobatan Kasus Dermatologi Elina Rahma; Dwi Indria Anggraini
JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Vol 8 No 2 (2020): JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia Volume 8.2 Edisi Maret - Agus
Publisher : BAPIN-ISMKI (Badan Analisis Pengembangan Ilmiah Nasional - Ikatan Senat Mahasiswa Kedokteran Indonesia)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.53366/jimki.v8i2.138

Abstract

Introduction: Oral fumaric esters acid (FAE) are interesting compounds in the field of dermatology. FAE works on skin cells and cytokine tissue. So far only a mixture of dimethylfumarate (DMF) and monoethylfumarate (MEF) has been approved for oral treatment of moderate to severe plaque psoriasis. Objective: To determine the use of oral fumaric acid esters (FAE) in the treatment of dermatology Method: The article was prepared using the literature review method, involving 34 literature sourced from books and journals. Results: DMF appears to be a major active component. It is important to emphasize the difference between fumaric acid and fumaric acid esters. Fumaric acid formulations are available as health supplements and are often marketed as natural alternative medicines for treating psoriasis. However, it is poorly absorbed by the intestine and excreted through urine without having any therapeutic effect. Discussion: Although the mode of action of FAE and its mechanism of action in psoriasis therapy is still unclear, the evidence shows that it has nothing to do with the Krebs cycle and the main active compound DMF. There is evidence that FAE is not only effective and safe in psoriasis but also non-granulomatous infectious diseases like annulare granulomas, necrobiosis lipoidica, and sarcoidosis. In vitro and animal studies show some activity in malignant melanoma as well. Conclusion: Oral fumaric acid (FAE) esters are widely used in some dermatology cases. Keywords: Dermatology, fumaric acid, psoriasis, sarcoidosis
Co-Authors Agustyas Tjiptaningrum Agustyas Tjiptaningrum Ahmad Fauzi Ahmad Sirajudin Alfi Yasmina Alwiyah, Fadilah Amira Zhafira Analia Analia Anggraeni Janar Wulan, Anggraeni Janar Annisa Adietya Pratama Annisa Cahyani Ayu Wulandari AYU WULANDARI Betta Kurniawan, Betta Dhipayasa Adirinarso Dian Isti Angraini Efrida Warganegara Elina Rahma Elina Rahma Emantis Rosa Erna Kristin Ety Apriliana Fauzi Ahmad Muda Fauziani, Andra Nabila Febe Sintia Kristiani Fitria Saftarina Graceciela, Yohana Eva Guntur Sulistyo Hakim, Lukmanul Hanna Mutiara, Hanna Hasril Mulya Budiman Helmi Ismunandar Hendra Tarigan Sibero Hendra Tarigan Sibero Hendra Tarigan Subero Hery Dian Septama Indri Windarti Isti Angraini, Dian iwan Dwiprahasto Jarir At Thobari Jhons Fatriyadi Suwandi Justiani, Andinni Aurellia Karima, Nisa Karimah, Nisa Kartika, Juspeni Kurniawaty, Evi Lania, Siska M. Fauzan Abdillah Rasyid M. Fitra Wardhana M. Syafei Hamzah Mayasari, Diana Muhamad Addin Syakir Muhamad Addin Syakir Muhammad Rafi Eka Putra Muhammad Syafei Hamzah Muhammad Yusran Muhammad Yusran Muhammad, Meizano Ardhi Mukhlis Imanto, Mukhlis Nisa Karimah Novita Carolia Pairulsyah Pairulsyah Piesta Prima Beta Pairul Putra, I Wayan Ardana Rahmatika, Achisna Rahmayani, Fidha Rani Himayani Rasmi Zakiah Oktarlina Rizki Hanriko Robert Bestak Rodiani Rodiani Rodiani, Rodiani Roro Rukmi Windi Perdani, Roro Rukmi Rudiyanto, Waluyo Sagia, Nabilla Alsa Sari, Mahala Ramah Silitonga, Yona Arisena Magdalena Suharmanto Suharmanto Syahrul Hamidi Nasution Syazili Mustofa Tri Umiana Soleha Tri Umiana Soleha Umniya Umniya Yisran, Muhammad Yulisna Yulisna Yustisya Khoirunnisa Zetira, Zihan